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Studi Kasus : Pengetahuan dan Persepsi Masyarakat Tentang Vaksin Covid-19 Teti Sutriati Tuloli; Nur Rasdianah; Nur Ain Thomas; Madania Madania; Devie Ariany Daud
Journal Syifa Sciences and Clinical Research Vol 4, No 3 (2022): Volume 4 Edisi 3 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i3.15930

Abstract

The Covid-19 vaccine is still often rejected by the public, especially those who are in places with a lack of information. This affects the public knowledge and perception of the Covid-19 Vaccine. The objective of this study is to determine the level of public knowledge and perception about the Covid-19 Vaccine and to determine the correlation between the characteristics of public and perception of the Covid-19 vaccine and the correlation between the level of public knowledge and perception about the Covid-19 Vaccine. This research is observational research with a quantitative descriptive research design using a cross-sectional approach. The findings indicate that the knowledge level of the people in Tuladenggi Village about the Covid-19 Vaccine in the low category is 22%, medium category is 46%, and high category is 33%. On the other hand, the perception of people in Tuladenggi Village about Covid-19 Vaccine in the negative category is 21%, the neutral category is 25%, and the positive category is 55%. Some of the respondents' characteristics, namely Age, Occupation, Education, Marital Status, Disease History, Vaccination Status, Vaccine Type, and Symptoms, have a significant correlation with perception, with a p-value lower than 0.005. In contrast, Gender and Religion do not have a significant correlation with perception, with a value, higher than 0.005. The correlation between the level of public knowledge about vaccine and perception obtains p-value of 0.000 (p0.05).
Perbedaan Pengetahuan dan Sikap Masyarakat Terhadap Pemberian Booklet dan Video Dagusibu Antibiotik Madania Madania; Nur Rasdianah; Nur Ain Thomas; Faramita Hiola; Sri Nur'ain E. Ahmad
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.15547

Abstract

Inappropriate use of antibiotics is common in the world, both in the community and in the hospital environment, which can lead to antibiotic resistance. The purpose of this study was to determine the knowledge and attitudes of the community before and after being given the booklet and video of dagusibu antibiotics and to determine the differences and influence of community knowledge and attitudes towards the administration of the booklet and video of the dagusibu antibiotic in Lopo Village, Batudaa Pantai Sub-District, Gorontalo Regency. This research applied a quasi-experimental design with the provision of booklets and videos before and after being given education. The number of samples was 74 which were taken using non-probability sampling technique. Research data were analyzed using Wilcoxon test and Man-Whitney test. The results showed that most of the community's knowledge before being given education was still in the sufficient category (57% booklet and 62% video), and the community's attitude was in the negative category (73% booklet and 84% percent video). Meanwhile, after being given education, the community's knowledge had increased to a good category (72% booklet and 86% videos), and community's attitudes had increased to a positive category (93% booklets and videos 98%) as well. Therefore, it can be concluded that there was a significant effect on increasing knowledge and attitude after being given booklets and videos (P0.1), and there was no significant difference between giving booklets and videos on increasing community’s knowledge and attitudes (P0.1).
Variasi Konsentrasi Bahan Pengikat Dari Pati Biji Durian (Durio Zibethinus)Terhadap Mutu Fisik Pada Formulasi Tablet Hisap Vitamin C Nur Ain Thomas; Fika Nuzul Ramadhani; Juliyanti Akuba; Ariani H. Hutuba
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.4317

Abstract

Starch of durian (Durio Zibethinus) seed is an accessible potential material to be utilized as binding agent in tablet. This study attempts to discover the influence of starch concentrate of durian seed in different percentages, i.e., 20%, 25%, and 30%, as binding agent towards the physical quality (by conducting tests i.e. weight uniformity test, hardness test, friability test, dissolution test, and organoleptic evaluation) towards vitamin C lozenges tablet formulation. Three formulae with different durian seed concentrate variation of F1 (20%), F2 (25%), and F3 (30%) were applied during the formulation of vitamin C lozenges. The result indicates that F2 and F3 formulae fulfilled all the test conducted, while the F1 formula only passed the weight uniformity test, taste response test, and organoleptic test. Based on the results of the study, F3 fulfilled all evaluations carried out, namely F3 4.07 kg hardness test, 0.30% friability test, 443.3 seconds dissolution test. F2 hardness test 3.79 kg, fragility test 0.34% solubility test 402 seconds. F1 hardness test 3.17 kg, fragility test 1.33%, soluble time test, 302.3 seconds. the conclusion obtained from the ANOVA-One way test is that there is a significant disintegration time difference of all formulas and continued by the Post-Hoct test to see the comparison of each formula with a confidence level (95%).
Edukasi Penggunaan Obat Antidiabetes di Bulan Ramadhan pada Masyarakat Desa Buata Kecamatan Botupingge Widy Susanti Abdulkadir; Nur Ain Thomas; Dizky Ramadani Putri Papeo
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 1 (2022): Vol 1 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (909.881 KB) | DOI: 10.3731/phar.soc.v1i1.14039

Abstract

Permasalahan utama pasien Diabetes Melitus (DM) adalah kepatuhan dalam minum obat dalam jangka Panjang. Pasien diabetes melitus yang mendapat terapi obat antidiabetes oral yang dapat menjalankan ibadah puasa di bulan Ramadhan harus mengikuti aturan baru minum obat, sehingga perlu diberikan informasi mengenai aturan minum obat yang tepat. Pemberian informasi melalui penyebaran brosur merupakan salah satu cara yang paling efektif untuk memperkenalkan aturan pemberian obat yang benar. Kegiatan tersebut berlokasi di Desa Buata, Kecamatan Botupingge, Kabupaten Bone Bolango. Hasil dari kegiatan ini, penderita diabetes melitus lebih siap menghadapi Ramadhan dengan aturan baru minum obat anti diabetes.
Edukasi dan Inovasi Keripik Bayam Sehat sebagai Alternatif Pangan Ibu Hamil Pencegah Anemia Nur Ain Thomas; Endah Nurrohwinta Djuwarno; Susanti Pakaya
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 3 (2022): Vol 1 Edisi 3 (2022)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (589.561 KB) | DOI: 10.3731/phar.soc.v1i3.18630

Abstract

Anemia   pada   ibu   hamil   berdampak   buruk   bagi   ibu   maupun   janin. Kemungkinan dampak buruk  terhadap ibu hamil yaitu proses persalinan yang membutuhkan waktu lama dan mengakibatkan perdarahan serta syok akibat kontraksi. Dampak buruk pada janin yaitu terjadinya    prematur, bayi lahir berat  badan rendah, kecacatan bahkan kematian bayi. Pengabdian ini bertujuan untuk  menghasilkan  produk  inovasi  yang  dapat  membantu  mengatasi  masalah anemia pada ibu hamil berupa pembuatan keripik bayam sehat. Pembuatan keripik bayam ini bertujuan untuk meningkatkan minat ibu hamil dalam mengkonsumsi sayuran yang kaya gizi dan dapat mencegah anemia disaat hamil. Kegiatan pengabdian kepada masyarakat ini bertujuan agar dapat mencegah kejadian anemia pada ibu hamil pada umumnya dan mencegah stunting pada anak pada khususnya. Pengabdian ini dilakukan dengan cara memberikan edukasi langsung mengenai pentingnya menghindari anemia disaat hamil pada ibu di saat posyandu ibu hamil dan membagikan keripik bayam sehat pada ibu hamil yang hadir. Pemberian edukasi dan pembagian keripik bayam pada masyarakat desa Bongohulawa khususnya ibu hamil mendapatkan respon yang baik karena sebagian besar masyarakat memiliki atensi yang tinggi melalui pertanyaan dan sangat menyukai produk olahan keripik bayam. Pengabdian ini memberikan manfaat yang besar bagi masyarakat desa agar mendapatkan pengetahuan mengenai manfaaat menghindari keadaan anemia disaat hamil dan memberikan informasi terkait produk olahan keripik bayam sehat.
Isolasi, Karakterisasi, dan Uji Antioksidan Fungi Endofit dari Tanaman Batang Kunyit (Curcuma domestica Val.,) Mahdalena Sy. Pakaya; Nur Ain Thomas; Hamsidar Hasan; Ariani H. Hutuba; Grasela Mbae
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.20341

Abstract

Endophytic fungi live in mutualistic symbiosis and can produce secondary metabolites similar to their host. This research aims to isolate, characterize, and test the antioxidant activity of secondary metabolites from turmeric stems. This research is experimental research where the method used for endophytic fungi isolation is the direct planting method, and antioxidant activity is tested using qualitative and quantitative methods with DPPH (1.1-diphenyl-2-picylhydrazyl). One fungal isolate was obtained with the fungal isolate code (BK). Based on macroscopic and microscopic characterization, the BK fungal isolate indicates the Deuteromycota class's characteristics. The qualitative antioxidant test results indicate that the fraction of BK endophytic fungal isolate indicates antioxidant activity, indicated by the yellow color against a purple background on the TLC plate observed under visible light. The respective ICso values for the ethyl acetate and n-hexane fractions were 52.989 µg/ml and 89.725 µg/ml, categorized as strong antioxidants. The methanol fraction had an ICso value of 119.02 µg/ml, categorized as moderate, while the pure supernatant fraction had an ICso value of 156.86 µg/ml, categorized as weak antioxidant activity.
Uji Penyembuhan Luka Bakar Gel Enzim Bromelin Menggunakan Carbopol 940 Secara In Vivo Nur Ain Thomas; Muhammad Taupik; Endah Nurrohwinta Djuwarno; Dizky Ramadani Putri Papeo; Nabila Novreini Djunaidi
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.20364

Abstract

Bromelain is a proteolytic enzyme or natural protease found in tissues, including the stem, fruit, and leaves of pineapple (Ananas comosus var. comosus) and other plant species of the Bromeliaceae family. Bromelain is known as an efficient debdriding agent because it is beneficial in  burn healing and tissue regeneration. This research aims to determine the effectiveness of bromelain enzyme for burns wounds in rabbits (Oryctolagus cuniculus). This research began with the optimization of carbopol 940 base preparations with variations in concentration, namely Formula 1 (F1) for 0,5%, Formula 2 (F2) for 1%, and Formula 3 (F3) for 1,5%. The evaluation of the gel formulation includes an organoleptic test, homogeneity test, pH test, viscosity test, adhesive force test, and spreadability test. The evaluation result indicates the base concentration in Formula 1 (F1) at 0,5% has met the requirements for a gel preparation. Formula 1 (F1) for 0,5, then combined with varying concentration of bromelain, namely Formula 1A (0,1%), Formula 1B (0,5%), and Formula 1C (1%). The gel formulation wa re-evaluated, including an organoleptic test, homogeneity test, pH test, viscosity test, adhesion test, spreadability test, irritation test, and in vivo test. In vivo effectiveness testing and irritation testing were conducted on five treatment groups, namely a positive control group (Bioplacenton®), Formula 1A (0,1%), Formula 1B (0,5%), Formula 1C (1%), and a group without treatment, then observed for 15 days. The observation data were processed using the One Way ANOVA test. Based on the results of the irritation test, Formula 1A (0,1%). Formula 1B (0,5%) and Formula 1C (1%) did not cause skin irritation. In the in vivo test, Formula 1C (1%) indicated the fastest recovery compared to other treatment groups, as evidenced by the decrease in wound diameter and visual observation, where the wound had started to close completely on day 15 of observation.