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. Yanwirasti
S3 Biomedik Ilmu Kedokteran Pascasarjana Universitas Andalas
Health Professions Medicine & Pharmacology

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Aktivitas Senyawa Isolasi Daun Surian terhadap Disfungsi Sel Endotel Hiperkholesterolemia Suhatri, .; Yanwirasti, .; Dachriyanus, .; Ellyza, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 2 (2012)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.529 KB)

Abstract

The protective effects of isolated compounds of ethylacetate fraction of surian's leaf (Toona sureni BL Merr) towards endothelial cell dysfunction on hypercholesterolemia have been investigated. Hypercholesterolemia was induced by atherogenic cocktail for the duration of 60 days. The protective effect was determined by Endothelia Derivate Relaxing Factor 9EDRF/NO) concentration. The result showed that isolated compounds oe ethyl acetate fraction of surian's leaf was able to protect the endothelia cell damage in hypercholesterolemia that can be seenn by increasing the bioavailability of NO serum (P<0.05).Keywords : flavonoid, cocktail, hypercholesterol and nitrogen mono oxide (EDRF)
Aktivitas Senyawa Isolasi Daun Surian terhadap Disfungsi Sel Endotel Hiperkholesterolemia Suhatri, .; Yanwirasti, .; Dachriyanus, .; Ellyza, .
Jurnal Farmasi Indonesia Vol 6, No 2 (2012)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.529 KB) | DOI: 10.35617/jfi.v6i2.128

Abstract

The protective effects of isolated compounds of ethylacetate fraction of surian's leaf (Toona sureni BL Merr) towards endothelial cell dysfunction on hypercholesterolemia have been investigated. Hypercholesterolemia was induced by atherogenic cocktail for the duration of 60 days. The protective effect was determined by Endothelia Derivate Relaxing Factor 9EDRF/NO) concentration. The result showed that isolated compounds oe ethyl acetate fraction of surian's leaf was able to protect the endothelia cell damage in hypercholesterolemia that can be seenn by increasing the bioavailability of NO serum (P<0.05).Keywords : flavonoid, cocktail, hypercholesterol and nitrogen mono oxide (EDRF)
Co-Authors . Dachriyanus . Ellyza Amri Bakhtiar Dian Handayani Ellyza Nasrul Suhatri Suhatri Yufri Aldi