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Journal : Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ

FORMULASI DAN UJI EVALUASI SEDIAAN STICK BALSEM DARI MINYAK ATSIRI SERAI DAPUR (Cymbopogon citratus) SEBAGAI ANALGESIK DAN AROMATERAPI RELAKSAN Ellyza Audhina Rachman; Titi Agni Hutahaen; Ainu Zuhriyah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 6 No. 2 (2023): Vol. 6, No.2, 2023
Publisher : Sam Ratulangi University

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Abstract

Lemongrass essential oil (Cymbopogon citratus) has potential as a medicine because it contains chemical compounds citronellal, citronellol, geraniol which work as analgesics and aromatherapy. One of the pharmaceutical preparations that can be used for analgesic and aromatherapy is a stick balm preparation because it can treat mild scale pain and stress. The aim of this study was to analyze the chemical compounds in citronella essential oil using the GCMS tool, to formulate it as a stick balm which has a function as an analgesic and aromatherapy as well as to evaluate the preparation. The method in this study is true experimental laboratory. Lemongrass essential oil is formulated into 4 different preparations. The results of testing citronella essential oil using GCMS did not meet the expectations of the researchers because the results did not read the compound being sought. The results of the data read the chemical compound groups that are thought to have the same function as citronellal, citronellol, geraniol. Aldehydes and alcohols. Lemongrass essential oil can be formulated into 4 balm sticks with different concentrations. Evaluation test of stick balm organoleptic test, homogeneity test, pH test, adhesion test, spreadability test, analgesic test, aromatherapy test and irritation test. The results of all preparation evaluation tests have met Indonesian national standards.  
The Effect of taro tuber (colocasia esculenta L) infusion formulation on reducing cholesterol levels in female mice (mus musculus): Effect of taro tuber (colocasia esculenta L) infusion formulation on reducing cholesterol levels in female mice (mus musculus) intan khoiriyah; titi agni hutahaen; ainu zuhriyah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 6 No. 2 (2023): Vol. 6, No.2, 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v6i2.50557

Abstract

Cholesterol is an essential building material for the body for the synthesis of important substances such as cell membranes and insulating materials around nerve fibers, as well as sex hormones, and kidney children, vitamin D, and bile acids. This study aims to determine which group of phytochemical compounds contained in liquid extract of taro tuber (Colocasia esculenta L.) has activity as a lowering of cholesterol levels and to determine whether taro tuber infusion (Colocasia esculenta L.) can reduce cholesterol levels in female mice. The dose used was the F1 dose of 0.3 ml/30 gram BW/day, the F2 dose was 0.6 ml/30 gram BW/day and the F3 dose was 0.9 ml/30 gram BW/day, in the K+ group using simvastatin 10 mg and K- using aqua injection. The results showed that at a dose of 0.3 ml/30 grams BW/day there was a relatively high reduction in cholesterol levels, namely 61 mg/dL, at a dose of 0.6 ml/30 grams BW/day it decreased by 48.8 mg/dL and at a dose of 0.9 ml /30 gram BW/day decreased with a low average of 19.4 mg/dL. However, a dose of 0.9 ml/30 gram BW/day is the best dose because it can reduce cholesterol levels quickly