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Journal : Journal of Fundamental and Applied Pharmaceutical Science

Formula Optimization of Feminine Liquid Soap from Garlic (Allium sativum Linn) Extract Ingenida Hadning; Astri Yunika
Journal of Fundamental and Applied Pharmaceutical Science Vol 1, No 2 (2021): February
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v1i2.10295

Abstract

Leucorrhoea is a condition frequently experienced by women. If it is not appropriately treated, it can become a more severe problem. Leucorrhoea is caused by “Candida albicans” fungus infection. Garlic (Allium sativum Linn) has antibacterial and antifungal activity, where garlic can inhibit the growth of the Candida albicans. This study aims to determine the optimal formulation of feminine liquid soap from garlic extract (Allium sativum Linn) with good physical quality; thus, garlic in treating Leucorrhoea can be practically easier. Optimization of liquid soap formulation used carbopol and sodium lauryl sulfate with various concentration variations. The method included organoleptic observation, pH, and specific gravity for one-month storage to obtain a good physical quality of liquid soap. The result showed that the formula with 10% sodium lauryl sulfate met the physical quality test requirements of feminine liquid soap; thus, the formulation of feminine liquid soap with 10% sodium lauryl sulfate was optimal.
The Formulation of Lotion Preparations of Betel Leaf Extract (Piper betle) Ingenida Hadning; Putri Kurnyaningtyas; Muhammad Thesa Ghozali
Journal of Fundamental and Applied Pharmaceutical Science Vol 1, No 1 (2020): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.010104

Abstract

Betel leaf (Piper betle) contains an essential oil that has extreme antiseptic power (bactericidal and fungicidal). Betel leaf (Piper betle) can be used in the treatment of Tinea versicolor or known in the community as panu. However, its use in the form of leaves is considered impractical by the public and also difficult to obtain. This research formulated betel leaf (Piper betle) into lotion preparations, so its use in the community can be more practical. This study aims to determine the type and concentration of the suspending agent used to produce lotion preparations from betel leaf extract (Piper betle), which has optimal physical quality. This research was an experimental study. The distillation of betel leaf (Piper betle) was carried out to get essential oils. The essential oils of betel leaf (Piper betle), which was used as an active substance in formulations, was 5%. Suspending agents that were used in this study were Arabic gum with concentrations of 10%, 15%, 20%, and CMC Na, with concentrations of 0.25%, 0.5%, and 1%. The formulation of lotion preparations included organoleptic observation, pH test, homogeneity test, and adhesion test. Based on the physical quality test of the lotion preparations that had been conducted, it can be concluded that the lotion preparations of betel leaf extract with 20% concentration of Arabic Gum suspending agent had physical qualities in accordance with lotion dosage criteria.