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All Journal Jurnal Ilmiah Manusia dan Kesehatan MAHESA : Malahayati Health Student Journal Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Detector: Jurnal Inovasi Riset Ilmu Kesehatan Lentera Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Jurnal Medika Nusantara Jurnal Malikussaleh Mengabdi
Wizar Putri Mellaratna
Universitas Malikussaleh
Religion Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Hubungan Pemberian ASI Eksklusif dengan Kejadian Dermatitis Atopik pada Balita di Rumah Sakit Umum Cut Meutia Aceh Utara Mulyati Sri Rahayu; Wizar Putri Mellaratna; Ghina Nurul Tasha
Jurnal Ilmiah Manusia Dan Kesehatan Vol 5 No 3 (2022): Jurnal Ilmiah Manusia dan Kesehatan
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v5i3.1836

Abstract

Dermatitis atopik (DA) adalah penyakit kulit inflamasi yang khas, bersifat kronis dan sering terjadi kekambuhan (eksaserbasi) terutama mengenai bayi dan anak-anak, namun dapat pula terjadi pada orang dewasa. Penyakit ini biasanya disertai dengan peningkatan kadar IgE dalam serum serta adanya riwayat rhinitis alergik dan asma pada keluarga maupun penderita. Penyakit alergi seperti dermatitis atopik pada anak-anak harus dicegah sedini mungkin karena anak memerlukan tumbuh dan kembang yang optimal. Faktor pencegah tersebut diantaranya dengan memberikan ASI eksklusif dimana selain memberikan nutrisi diduga mampu melindungi bayi terhadap penyakit alergi seperti dermatitis atopik. Penelitian ini bertujuan untuk mengetahui hubungan antara pemberian ASI eksklusif dengan kejadian dermatitis atopik pada balita di Rumah Sakit Umum Cut Meutia Aceh Utara. Metode penelitian yang digunakan adalah observasional analitik dengan pendekatan potong lintang (cross sectional) dengan teknik purposive sampling. Hasil penelitian menunjukkan terdapat 46 sampel yang terdiri dari balita perempuan 23 orang (50%) dan balita laki-laki 23 orang (50%) dengan usia terbanyak yaitu pada rentang usia 7-24 bulan (50%). Responden yang menderita dermatitis atopik lebih banyak tidak mendapatkan ASI eksklusif yaitu 14 orang (63,6%). Berdasarkan analisis uji Chi Square, didapatkan nilai OR 0,484 (95%=0,148-1,578) dan nilai p yaitu 0,226 (p>0,05). Kesimpulan dari penelitian ini adalah tidak terdapat hubungan yang signifikan antara pemberian ASI eksklusif terhadap kejadian dermatitis atopik pada balita di Rumah Sakit Umum Cut Meutia Aceh Utara.
Perbandingan Terapi Peeling Kimiawi Dengan Glycolic Acid 35% dan Mandelic Acid 30% dalam Menurunkan Derajat Keparahan Akne Vulgaris Wizar Putri Mellaratna; Anna Millizia; Bela Nurfitri Erida; Ghina Nurul Tasha
Jurnal Ilmiah Manusia Dan Kesehatan Vol 6 No 1 (2023): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v6i1.1931

Abstract

Introduction: Acne vulgaris is a pilosebaceous unit disorder which is mostly seen in adolescents and adults with approximately 85% occurs at the age of 12-25 years. Methods: The purpose of this study is to know the comparison between chemical peeling therapy with 35% glycolic acids (GA) and 30% mandelic acids (MA) to reduce the severity of acne vulgaris. A total of 30 medical students suffering from mild to severe acne vulgaris were involved in this study. The patients were randomly divided into two groups, with one group receiving 35% GA and the other group receiving 30% MA peels at an interval of 4 weeks for two sessions. The Mann Whitney test is used to analysis the difference between chemical peeling therapy with 35% GA and 30% MA to reduce the severity of acne vulgaris. The p value < 0,05 is considered statistically significant. Results and discussion: majority of the patients are females (70,0%), age 14 years olds (50,0%), duration of acne vulgaris 7,8 and 10 years (16,7%). There is no significant difference between 35% GA and 30% MA in reducing the severity of acne vulgaris (p > 0,05). Chemical peels with MA has an antibacterial effect and is used to treat others skin disorders such as acne, photoaging, and pigmentation disorders. GA peels is proven to be effective in the treatment of inflammation and non-inflammation acne. Conclusions: there is no difference between chemical peels with 35% GA and 30% MA in reducing the severity of acne vulgaris. Keywords: acne vulgaris; chemicals peels, treatment, severity of acne
Faktor-Faktor yang Berhubungan dengan Tingkat Kecacatan Penderita Kusta di Puskesmas Wilayah Kerja Kota Lhokseumawe Tahun 2016 - 2020 Nora Maulina; Najwa Zakiyya; Wizar Putri Mellaratna
Jurnal Ilmiah Manusia Dan Kesehatan Vol 6 No 1 (2023): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v6i1.1956

Abstract

Kusta atau yang biasa dikenal dengan lepra atau Morbus Hansen merupakan penyakit menular menahun yang diakibatkan oleh Mycobacterium lepra. Kusta jika tidak segera ditangani akan bisa menimbulkan cacat pada bagian tubuh, seperti wajah, anggota gerak, dan saraf tepi. Risiko adanya kecacatan ini dapat dipengaruhi oleh beberapa faktor. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan tingkat kecacatan penderita kusta di puskesmas wilayah kerja Kota Lhokseumawe pada tahun 2016-2020 yaitu usia, jenis kelamin, tingkat pendidikan, tipe kusta dan lama sakit. Metode penelitian ini adalah observasional analitik dengan desain penelitian cross sectional. Teknik pengambilan sampel menggunakan total sampling dengan jumlah sampel 47 responden. Seluruh proses pengolahan data dan analisis menggunakan SPSS 25. Hasil penelitian ini didapatkan karakteristik responden sebagai berikut : usia produktif (74,5%), laki-laki (61,7%), tingkat pendidikan rendah (46,8%) dan sedang (46,8%). Hasil uji statistik menggunakan uji Kolmogorov-Smirnov dengan α = 0,05 didapatkan faktor usia (p=1,000), jenis kelamin (p=1,000), tingkat pendidikan (p=1,000), tipe kusta(p=0,905) dan lama sakit (p=0,982) tidak memiliki hubungan dengan tingkat kecacatan kusta. Dari hasil ini dapat disimpulkan bahwa tidak terdapat hubungan antara usia, jenis kelamin, tingkat pendidikan, tipe kusta dan lama sakit terhadap tingkat kecacatan penderita kusta di puskesmas wilayah kerja Kota Lhokseumawe. Kata kunci : kusta, tingkat kecacatan kusta, karakteristik
PATOGENESIS SINDROM STEVENS-JOHNSON (SSJ) DAN NEROLISIS EPIDERMAL TOKSIK (NET) Wizar Putri Mellaratna
Lentera : Jurnal Ilmiah Sains, Teknologi, Ekonomi, Sosial, dan Budaya Vol 5 No 2 (2021): Lentera, Mei 2021
Publisher : LPPM Universitas Almuslim

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Nekrolisis Epidermal Toksik (NET) dan Sindrom Stevens-Johnson merupakan reaksi mukokutaneus akut yang mengancam jiwa dengan karakteristik terjadinya pengelupasan epidermis. Perkembangan terkini dalam studi farmakogenomik menemukan bahwa terdapat predisposisi genetic untuk SSJ/NET. Khususnya, terdapat hubungan genetik yang kuat antara Human Leucocyte Antigen (HLA) dan obat-obatan tertentu menjadikan perlunya pemeriksaan tess krining terlebih dahulu terhadap faktor genetic ini untuk mencegah terjadinya SSJ-NET. Sindrom Steven Johnsons/Nekrolisis Epidermal Toksik di kelompokkan ke dalam reaksi hiper sensitivitas tipe IVc. Terdapat tiga model dalam terjadinya SSJ/NET yaitu model hapten-prohapten, konsep p-idanaltered repertoire. Granulisin merupakan protein sitolitik yang dihasilkan dan disekresikan oleh limfosit T sitotoksik (CTLs) dan sel NK. Patogenesis SSJ/NET terjadi melalui kerentanan genetik tertentu (terkait HLA) dan melalui mekanisme imunologik. Model reaksi hiper sensitivitas yang terjadi umumnya berkaitan dengan hiper sensitivitas tipe IVc, yang umumnya didominasi oleh sel T CD8 sitotoksik dan sel T CD4, sertasel NK.
Furunkel Folikulitis Et Tinea Corporis Wizar Putri Mellaratna; Indri Yustati Ritonga
Jurnal Anestesi Vol. 1 No. 4 (2023): Oktober : Jurnal Anestesi
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v1i4.509

Abstract

Folliculitis is a bacterial skin infection caused by Staphylococcus aureus and Streptococcus sp. If the surrounding tissue is also affected, it is called a furuncle. About 20% of individuals have S. aureus colonization, while S.aureus carriers are found in 60% of healthy individuals.
Erisipelas Wizar Putri Mellaratna; Rizqa Shafrina
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 1 No. 3 (2023): Agustus : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Politeknik Pratama Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v1i3.2271

Abstract

Erysipelas is an infection of the nonnecrotic superficial skin accompanied by lymphangitis. This infection will cause a clinical picture in the form of well-defined erythematous plaques. Most cases of erysipelas are caused by bacteria, most often the normal skin flora such as Streptococcus bacteria but erysipelas can also be caused by S. aureus and group C or G Streptococcus. Erysipelas can occur at any age. Erysipelas is closely related to the patient’s physical condition and cellular immune status which underlies or facilitates the occurrence of infections, including chronic systemic diseases suffered by these patients, such as diabetes mellitus, immunocompromised states. The lower extremities are the most common predilection for erysipelas. Most erysipelas patients come for treatment with the main complaint of swelling, redness, and pain experienced by the patient accompanied by other complaints such as burning and itching which are predisposing factors to the occurrence of this infection. The diagnosis of erysipelas is based on anamnesis, physical examination and laboratory tests. The management of erysipelas is the administration of antibiotics and wound care.
Analisis efektivitas Probiotik Oral Sebagai Antibakteri Terhadap Bakteri Stapylococcus epidermidis Muhammad Ezyra Widya Aqshal; Cut Sidrah Nadira; Wizar Putri Mellaratna
Jurnal Ilmiah Manusia Dan Kesehatan Vol 6 No 3 (2023): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v6i3.2293

Abstract

Staphyloccus epidermidis merupakan salah satu bakteri yang menyebabkan acne vulgaris. Angka kejadian Acne vulgaris berkisar 85 % dan terjadi pada usia 14- 17 tahun pada wanita dan 16-19 tahun pada laki laki. Acne vulgaris umumnya lebih banyak terjadi pada laki - laki dibandingkan dengan wanita pada rentang usia 15-44 tahun yaitu 34 % pada laki - laki dan 27 % pada wanita. Tujuannya adalah mengetahui perbedaan efek probiotik dengan konsentrasi 18x108 CFU/ml,21x108 CFU/ml dan 30x108 CFU/ml terhadap diameter zona hambat pertumbuhan antibakteri Staphyloccus epidermidis. Metode menggunakan tiga konsentrasi probiotik yang mengandung Lactobacillus acidophilus yang diulang lima kali untuk melihat efek zona hambat pertumbuhan Staphyloccus epidermidis yang ditumbuhkan pada Mueller-Hinton Agar. Pengukuran zona hambat dilakukan setelah kultur selama 48 jam. Perbedaan zona hambat antara kelompok uji dianalisis dengan one-way ANOVA. Hasil analisis menunjukkan bahwa probiotik dengan konsentrasi 18x108 CFU/ml mempunyai rata-rata zona hambat 17,56 mm, konsentrasi 21x108 CFU/ml mempunyai rata-rata zona hambat 13,56 mm, dan konsentrasi 30x108 CFU/ml memiliki rata-rata zona hambat 13,1 mm. Kesimpulan ialah terdapat perbedaan zona hambat Lactobacillus acidophilus terhadap pertumbuhan bakteri Staphyloccus epidermidis dengan zona hambat terbesar pada konsentrasi 18x108 CFU/ml
ANALYSIS OF FACTORS INFLUENCING ADHERENCE TO ANTIRETROVIRAL MEDICATION (ARV) IN HIV/AIDS PATIENTS BASED ON INFORMATION, MOTIVATION, BEHAVIORAL SKILLS AT CUT MEUTIA GENERAL HOSPITAL Yuziani; Mulyati Sri Rahayu; Harvina Sawitri; Wizar Putri Mellaratna; Anna Millizia; Yofinda Aurelia Rizkita; Rani Mulya Safitri
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 4 No. 2 (2023): June
Publisher : PT. Radja Intercontinental Publishing | ISSN: XXXX-XXXX

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v4i2.77

Abstract

HIV (Human Immunodeficiency Virus), included in the Retroviridae family, is a virus that causes AIDS (Acquired Immunodeficiency Syndrome), a syndrome caused by a decrease in the body's immune system. Compliance with taking medication on HIV/AIDS clients is very important, non-adherence in implementing therapy will reduce the effectiveness of ARV drugs and even increase viral resistance in the body. Information, motivation and ability to behave are fundamental determinants of a behavior in adherence to taking medication. This study will analyze the factors associated with adherence to taking ARV medication in HIV/AIDS patients to find out the causes of nonadherence to taking ARV medication. This type of research uses descriptive research methods while based on the time dimension the research uses a cross sectional design. The research was conducted at Cut Meutia General Hospital. This research was conducted from 2018-2019. The sampling technique in this study used the total sampling method. The population in this study were all HIV/AIDS patients who were treated at the VCT and CST clinics at Cut Meutia Hospital, North Aceh District, which were recorded until 2018-2019, totaling 62 people. The results of this study found that respondents at Cut Meutia Hospital had low information of 90.0% regarding adherence to ARV drug use. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. The sampling technique in this study used the total sampling method. The population in this study were all HIV/AIDS patients who were treated at the VCT and CST clinics at Cut Meutia Hospital, North Aceh District, which were recorded until 2018-2019, totaling 62 people. The results of this study found that respondents at Cut Meutia Hospital had low information of 90.0% regarding adherence to ARV drug use. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. The sampling technique in this study used the total sampling method. The population in this study were all HIV/AIDS patients who were treated at the VCT and CST clinics at Cut Meutia Hospital, North Aceh District, which were recorded until 2018-2019, totaling 62 people. The results of this study found that respondents at Cut Meutia Hospital had low information of 90.0% regarding adherence to ARV drug use. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. The population in this study were all HIV/AIDS patients who were treated at the VCT and CST clinics at Cut Meutia Hospital, North Aceh District, which were recorded until 2018-2019, totaling 62 people. The results of this study found that respondents at Cut Meutia Hospital had low information of 90.0% regarding adherence to ARV drug use. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. The population in this study were all HIV/AIDS patients who were treated at the VCT and CST clinics at Cut Meutia Hospital, North Aceh District, which were recorded until 2018-2019, totaling 62 people. The results of this study found that respondents at Cut Meutia Hospital had low information of 90.0% regarding adherence to ARV drug use. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. Respondents at Cut Meutia Hospital had low motivation of 96.7% for adherence to ARV drug use. Respondents at Cut Meutia Hospital had low behavioral skills of 96.7% for compliance with the use of ARV drugs. .
Pemfigus Vulgaris Wizar Putri Mellaratna; Cut Winda Agustia
Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Vol. 2 No. 2 (2023): Oktober: Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v2i2.1758

Abstract

Pemphigus vulgaris (PV) is a chronic intraepidermal bullous disease that causes extensive skin lesions. Pemphigus vulgaris initially appears in the form of vesicles and loose-walled bullae that break easily on normal skin, which then develop into bullae with an erythematous base, then rupture, causing erosion, excoriation, which is usually accompanied by crusting and pain. Bullae occur due to damage or damage to intercellular adhesion due to IgG autoantibodies to desmoglein 3, causing epithelial cells called acantholysis (epidermal cell separation reaction). The hallmark of pemphigus is erosion that extends into normal skin by pulling on remnants of the blister wall or rubbing on the periphery of an active lesion. Erosion can be induced on normal-appearing skin away from the active lesion by mechanical stress or shear, a phenomenon known as the Nikolsky sign. Prognosis before corticosteroids are used, death occurs in 50% of patients within the first year. Treatment with corticosteroids makes the prognosis better. Pemphigus vulgaris in the early stages will be easier to control than those with widespread manifestations, the mortality rate will increase if there is a delay in therapy.
Gambaran Karakteristik Sosiodemografi Penderita Kusta di Kabupaten Aceh Utara Tahun 2017-2021 Islah Salsabila; Cut Khairunnisa; Wizar Putri Mellaratna
MAHESA : Malahayati Health Student Journal Vol 3, No 11 (2023): Volume 3 Nomor 11 (2023)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v3i11.11481

Abstract

ABSTRACT Introduction: Leprosy is an infectious disease which is still a health problem in Indonesia. Indonesia is ranked third as the country with the most leprosy patients in the world after India and Brazil. In 2021, it was reported that there were 10.976 new cases of leprosy in Indonesia and the prevalence of leprosy in Aceh in 2021 was found to be 321 cases of leprosy. Research objective: to describe the sociodemographic characteristics (age, sex, type of leprosy and level of disability) of leprosy patients in North Aceh District in 2017-2021. Method: descriptive study with a cross-sectional approach to leprosy patients in North Aceh District. Samples were taken by using total sampling technique. Results and Discussion: In this study, it was found that the distribution of leprosy patients based on age was mostly found in the adult age categories, which is 26-45 years with 76 people (44.4%), as many as 100 people with leprosy (58.5%) were men, people with the Multibacillary type was found in 119 people (69.6%) and there were 157 patients with grade 0 disabilities (91.8%). Conclusion: The distribution of leprosy based on age was mostly found in the adult age category (26-45 years), the majority of leprosy patients were male, the most common type of leprosy was Multibacillary leprosy and the majority of leprosy patients have grade 0 defects.  Keywords: Leprosy, Characteristic, Sociodemography  ABSTRAK Pendahuluan: Kusta merupakan salah satu penyakit menular yang masih menjadi masalah kesehatan di Indonesia. Indonesia menempati peringkat ketiga negara dengan penderita kusta terbanyak di dunia setelah India dan Brazil.  Tahun 2021, dilaporkan terdapat sebanyak 10.976 kasus baru kusta di Indonesia dan prevalensi penyakit kusta di Aceh pada tahun 2021 ditemukan sebanyak 321 kasus kusta. Tujuan penelitian: untuk mengetahui gambaran karakteristik sosiodemografi (usia, jenis kelamin, tipe kusta dan tingkat cacat kusta) penderita kusta di Kabupaten Aceh Utara tahun 2017-2021. Metode: penelitian deskriptif dengan pendekatan cross-sectional terhadap penderita kusta di Kabupaten Aceh Utara. Sampel diambil dengan teknik pengambilan sampel total sampling. Hasil dan pembahasan: penelitian ini didapatkan bahwa distribusi penderita kusta berdasarkan usia sebagian besar ditemukan pada kategori usia dewasa, yaitu 26-45 tahun sebanyak 76 orang (44,4%), sebanyak 100 orang penderita kusta (58,5%) adalah laki-laki, penderita penyakit kusta dengan tipe Multibasiler ditemukan sebanyak 119 orang (69,6%) dan terdapat 157 penderita mengalami cacat tingkat 0 (91,8%). Kesimpulan: Distribusi penderita kusta berdasarkan usia paling banyak ditemukan pada kategori usia dewasa (26-45 tahun), mayoritas penderita kusta berjenis kelamin laki-laki, paling banyak ditemukan penderita kusta dengan tipe kusta Multibasiler dan mayoritas penderita kusta mengalami cacat tingkat 0. Kata Kunci : Kusta, Karakteristik, Sosiodemografi
Co-Authors Adi Rizka Anna Millizia Bela Nurfitri Erida Cut Khairunnisa Cut Sidrah Nadira Cut Winda Agustia Ghina Nurul Tasha Harvina Sawitri Indri Yustati Ritonga Islah Salsabila Maulina, Nora Muhammad Ezyra Widya Aqshal Muhammad Naufal Arif Mulyati Sri Sri Rahayu Najwa Zakiyya Rani Mulya Safitri Rizqa Shafrina Yofinda Aurelia Rizkita Yuziani Yuziani