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EFEK SAMPING EKSTRAK ETANOL 96% DAN 70% HERBA KEMANGI (Ocimum americanum L.) YANG BERSIFAT ESTROGENIK TERHADAP KADAR ASAM URAT PADA TIKUS PUTIH Rina Siti Nurul Husna; E. Mulyati Effendi; Hera Maheshwari
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 16, No 2 (2016): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v16i2.745

Abstract

The aims of study was determine the effect of 70% and 96% ethanolic extracted of estrogenic herb basil on increasing or decreasing the level of uric acid in female rats. The animals used were 24 rats that were divided into six groups which consist of four animals each. Group I was animal that were given at a dose 0,7g/200g BW of 70% ethanolic extracted basil. Group II was the same concentration of basil extract at a dose 0,8g/200g BW. Group III was also the concentration of basil extract at a dose 0,9g/200g BW. Group IV was animals that were given at a dose 0,7g/200g BW of  96% ethanolic extracted basil. Group V was the same concentration of basil extract at a dose 0,8g/200g BW. Group VI was also the concentration of basil extract at a dose 0,9g/200g BW. The result showed that the ethanol extract of the basil herb had no significantly affected uric acid, there was even a tendency  to decrease lower uric acid level after given during 15 days. Key words : Uric Acid, Estrogenic, Herb Basil
EFEKTIVITAS KOMBINASI EKSTRAK DAUN MENGKUDU (Morinda citrifolia ) dan ASAM KANDIS SEBAGAI PENURUN BERAT BADAN PADA TIKUS PUTIH JANTAN GALUR Sprague-Dawley Shinta Suci Anggraena; Min Rahminiwati; E. Mulyati Effendi
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 17, No 1 (2017): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v17i1.810

Abstract

This study aimed to determine the effect of a combination of extracts of Noni leaves (Morinda citrifolia L) and fruit kandis (Garcinia cowa Roxb) on body weight of male rats induced by high- fat calories food Test animals were used 25 rats male Sprague Dawley strain age of 2 months with body weight ± 200 g. White mice were divided into 5 groups of 4 rats each. The treatment committed agains an obesity rats. The treatment group consisted of rats doses of 1 (8,75mg/kgBB noni leaves ekstract and sour fruit kandis 7mg/kgBB), dose II (4,75 mg/kgBB noni leaves ekstract and sour fruit kandis 3,5mg/kgBB), dose III (17,5 mg/kgBB noni leaves ekstract and sour fruit kandis 14mg/kgBB), the positive control group were given Orlistat and negative group were only given food to eat and drink. The observed parameters include weight loss, abdominal width, body length, skin fold, body mass indeks. The results showed that noni leaf extract and fruit kandis can be used as a weight loss with the most effective dose is 17,5 mg /kg BB noni leaf + 14 mg/kg BB fruit kandis with the most effective treatment is 14 days. Key words : Noni Leaf and fruit kandis, Feeding a High-Fat Calories,  Obesity Parameters, Rats male Sprague Dawley.