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All Journal Indonesian Journal of Science and Technology
Agung W. M. Yodha
Politeknik Bina Husada Kendari
Computer Science & IT Environmental Science

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Phytochemical Profile and Biological Activities of Ethylacetate Extract of Peanut (Arachis hypogaea L.) Stems: In-Vitro and In-Silico Studies with Bibliometric Analysis Idin Sahidin; N. Nohong; Marianti A. Manggau; A. Arfan; W. Wahyuni; Iren Meylani; M. Hajrul Malaka; Nur Syifa Rahmatika; Agung W. M. Yodha; Nur Upik En Masrika; Abdulkadir Kamaluddin; Andini Sundowo; Sofa Fajriah; Rathapon Asasutjarit; Adryan Fristiohady; Rina Maryanti; Nur Indri Rahayu; M. Muktiarni
Indonesian Journal of Science and Technology Vol 8, No 2 (2023): (ONLINE FIRST) IJOST: September 2023
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v8i2.54822

Abstract

The utilization of the stems, leaves, and hulls of peanuts (Arachis hypogea) is not as popular as the seeds. This study aimed to investigate the chemical contents and pharmacological activities of A. hypogaea stems in-vitro and in-silico. This study was also completed with bibliometric analysis. The methanol extract (ME) was reextracted by ethylacetate to get ethyl acetate extract (EAE). The chemical contents of EAE were analyzed by phytochemical screening, Liquid Chromatography-Mass Spectroscopy (LC-MS/MS), TPC (Total Phenolic Content), and TFC (Total Flavonoid Content). In-vitro and in-silico studies evaluated antioxidant potency, toxicity, and cytotoxicity toward MCF-7 cell lines. The results showed that EAE contained terpenoids, flavonoids, alkaloids, and phenolics which were supported by LC-MS/MS data. The EAE was categorized as a very strong antioxidant and moderately active in both cytotoxicity and toxicity.
Co-Authors Abdulkadir Kamaluddin Adryan Fristiohady Andini Sundowo Arfan Arfan Idin Sahidin Iren Meylani M. Hajrul Malaka Marianti A. Manggau Masrika, Nur Upik En Muktiarni, Muktiarni N. Nohong Nur Indri Rahayu Nur Syifa Rahmatika Rathapon Asasutjarit Rina Maryanti Sofa Fajriah Wahyuni Wahyuni