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All Journal Indonesian Journal of Science and Technology Jurnal Surya Medika MOSIRAHA : Jurnal Pengabdian Farmasi Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Borneo Journal of Pharmacy
Adryan Fristiohady
Universitas Halu Oleo
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Analisis Kualitas Pelayanan terhadap Kepuasan Pasien Rawat Jalan di Puskesmas Puuwatu Kota Kendari menggunakan Metode SERVQUAL Adryan Fristiohady; La Ode Muhammad Fitrawan; Yusniati Dwi Pemudi; Sunandar Ihsan; Ruslin Ruslin; Mentarry Bafadal; Nurwati Nurwati; Ruslan Ruslan
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1442

Abstract

The quality of outpatient services can be measured by the SERVQUAL model that takes into account 5 dimensions, namely tangible, reliability, responsiveness, assurance, and empathy. The purpose of this study was to look at the effect of service quality on outpatient satisfaction at the Apotek Puskesmas Puuwatu Kota Kendari. The subjects in this study were 34 outpatients. The analysis technique used is gap analysis to compare expectations and reality received by patients, normality test data based on questionnaire patient satisfaction that has been tested for validation. The results of this study indicate the average value of the gap in the pharmacy of Apotek Puskesmas Puuwatu Kota Kendari amounting to 0.27. From the value of the gap, the lowest gap value in the pharmacy center of Puuwatu is the place of service, and the provision of inadequate drug information of -0.24. Based on the paired t-test where significant value> 0.05 then Ho is rejected and Ha accepted so that means a significant difference between the quality of service to the satisfaction of patients in Apotek Puskesmas Puuwatu Kota Kendari. This study concludes that there is a significant gap between expectations and reality at the Apotek Puskesmas Puuwatu Kendari City
Phytochemical Profile and Biological Activities of Ethylacetate Extract of Peanut (Arachis hypogaea L.) Stems: In-Vitro and In-Silico Studies with Bibliometric Analysis Idin Sahidin; N. Nohong; Marianti A. Manggau; A. Arfan; W. Wahyuni; Iren Meylani; M. Hajrul Malaka; Nur Syifa Rahmatika; Agung W. M. Yodha; Nur Upik En Masrika; Abdulkadir Kamaluddin; Andini Sundowo; Sofa Fajriah; Rathapon Asasutjarit; Adryan Fristiohady; Rina Maryanti; Nur Indri Rahayu; M. Muktiarni
Indonesian Journal of Science and Technology Vol 8, No 2 (2023): (ONLINE FIRST) IJOST: September 2023
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v8i2.54822

Abstract

The utilization of the stems, leaves, and hulls of peanuts (Arachis hypogea) is not as popular as the seeds. This study aimed to investigate the chemical contents and pharmacological activities of A. hypogaea stems in-vitro and in-silico. This study was also completed with bibliometric analysis. The methanol extract (ME) was reextracted by ethylacetate to get ethyl acetate extract (EAE). The chemical contents of EAE were analyzed by phytochemical screening, Liquid Chromatography-Mass Spectroscopy (LC-MS/MS), TPC (Total Phenolic Content), and TFC (Total Flavonoid Content). In-vitro and in-silico studies evaluated antioxidant potency, toxicity, and cytotoxicity toward MCF-7 cell lines. The results showed that EAE contained terpenoids, flavonoids, alkaloids, and phenolics which were supported by LC-MS/MS data. The EAE was categorized as a very strong antioxidant and moderately active in both cytotoxicity and toxicity.
SOSIALISASI PEMAHAMAN TENTANG VCO (VIRGIN COCONUT OIL) DESA LEPPE, KECAMATAN SOROPIA, KABUPATEN KONAWE Adryan Fristiohady; Muhammad Ilyas Yusuf; Asniar Pascayantri; Sahidin; Muhamad Handoyo Sahumena; Wahyuni; Laode Muhamad Mbuyang Nadia; Grasiana Eka E.Y.G; Wa Ode Norma; Yamin Yamin; Wa Kuasa Baka; Ilma Mustaqima Rianse
Mosiraha: Jurnal Pengabdian Farmasi Vol. 1 No. 1 (2023): Edisi April 2023
Publisher : Fakultas Farmasi Universitas Halu Oleo

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Abstract

Buah kelapa di wilayah pesisir Desa Leppe Kecamatan Soropia kabupaten Konawe, Provinsi Sulawesi Tenggara hanya dijual secara gelondongan. Tujuan pelatihan untuk memotivasi masyarakat agar berdaya dengan memanfaatkan potensi alamnya menjadi  lebih ekonomis dan meningkatkan pemahaman tentang VCO Khalayak sasarannya adalah 20 orang masyarakat Desa Leppe. Kegiatan ini melibatkan mitra, baik dari pihak masyarakat yang bergiat di bidang pembuatan produk VCO, ibu-ibu penggerak Pemberdayaan Kesejahteraan Keluarga (PKK), Kegiatan pengabdian dilakukan melalui metode penyuluhan dan telah berlangsung dengan baik, lancar, serta mendapat respon yang positif dari para peserta. Transfer pengetahuan, baru ini telah memotivasi masyarakat untuk berwirausaha dengan membuat VCO murni bagi kesehatan tubuh seperti antibakteri, antivirus, dan anti jamur. Proses pembuatan VCO adalah dengan cara fermentasi tidak mengalami proses pemanasan dan tidak ada penambahan zat zat kimia. Diharapkan pelatihan ini ditindak lanjuti dengan pelatihan pembuatan produk VCO agar bisa dikemas dan bisa di perjual belikan.
Sosialisasi Paradigma Hidup Sehat Sebagai Konsep Promotif dan Preventif Penyakit Menular dalam Upaya Mendukung SDGs di SMA Negeri 2 Kendari Adryan Fristiohady; Nita Trinovitasari; Rifa'atul Mahmudah; Intan Permata Putri
Mosiraha: Jurnal Pengabdian Farmasi Vol. 1 No. 2 (2023): Edisi Agustus 2023
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/mosiraha.v1i2.25

Abstract

Penyakit menular yang masih tinggi di Sulawesi Tenggara adalah DBD (Demam Berdarah Dengue). Salah satu cara mencegah penyakit DBD adalah dengan melakukan 3M (Menguras, Mengubur, dan Menutup) yang merupakan program arbovirosis pemerintah. Tujuan kegiatan ini adalah memberikan pemahaman sejak dini kepada siswa SMA Negeri 2 Kendari tentang penyakit menular demam berdarah dan cara pencegahan penyakit DBD dengan gerakan 3M. Metode yang digunakan adalah ceramah dan tanya jawab dengan media leaflet. Hasil dari kegiatan ini adalah meningkatnya pemahaman peserta yang dapat dilihat dari perubahan nilai pretest dan posttest. Pada saat pretest peserta yang pemahamannya dikategorikan rendah sebanyak 30 siswa, sedang 20 siswa dan tinggi 10 siswa. Pada saat posttest jumlah peserta yang pemahamannya dikategorikan rendah dan sedang menurun menjadi 5 siswa dan 15 siswa, sedangkan yang dikategorikan tinggi meningkat menjadi 40 siswa. Kesimpulan dari kegiatan ini adalah penyelenggara berhasil memberikan edukasi dan sosialisasi terkait penyakit menular DBD dan cara pencegahannya dengan 3M.
Apotek Hidup: Upaya Pelestarian Penggunaan Obat Tradisional di Masyarakat melalui Pemanfaatan Tanaman Obat Keluarga Idin Sahidin; Gusti Ray Sadimantara; Muhammad Hajrul Malaka; Muhammad Azdar Setiawan; Nur Saadah Daud; Adryan Fristiohady; Yulianti Fauziah; Sernita Sernita; Musdalipah Musdalipah; Agung Wibawa Mahatva Yodha; Wahyuni Wahyuni
Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Vol 1 No 1 (2023): NADIKAMI: Januari 2023
Publisher : POLITEKNIK BINA HUSADA KENDARI

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Abstract

Penduduk Desa Lamomea Kecamatan Konda Kabupaten Konawe Selatan Provinsi Sulawesi Tenggara sebagian besar masyarakatnya berpendidikan minimal rata-rata lulusan SMA, sehingga pengetahuan tentang budidaya dan pemanfaatan tanaman obat masih sangat kurang. Salah satu upaya yang dapat dilakukan untuk membantu pelaksanaan program pemerintah terkait pemanfaatan tanaman obat. Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk menyampaikan informasi tentang tanaman obat melalui sosialisasi, diskusi, dan praktik langsung budidaya tanaman obat keluarga di pekarangan rumah. Evaluasi peningkatan pengetahuan masyarakat dilakukan dengan pre-test dan post-test. Hasil dari kegiatan ini menunjukkan adanya peningkatan pengetahuan dasar tentang jenis, manfaat, dan cara membuat ramuan. Kegiatan pengabdian ini menunjukkan adanya keberhasilan dan sangat bermanfaat, karena adanya peningkatan pengetahuan dengan skor rata-rata lebih dari 60 yaitu skor rata-rata post-test 86.11 dibandingkan saat sebelum kegiatan dari nilai rata-rata pre-test 59.72. Masyarakat menunjukkan keterampilan yang memadai saat melakukan praktik langsung mulai dari penanaman, hingga pemeliharaan tanaman. Hasil budidaya tanaman obat ini, selain merupakan upaya pelestarian tanaman obat tradisional, juga mampu menghasilkan produk kosmetik yang kemudian dapat di manfaatkan sebagai produk herbal atau dijual untuk menambah nilai ekonomi.
Anti-inflammatory Activity of Pharmaceutical Gel of Ethanolic Extract from Marine Sponge Xestospongia Sp Wa Ode Sitti Zubaydah; Wahyuni Wahyuni; Sahidin Sahidin; Tian Amalia Halik; Rina Andriani; Astrid Indalifiany; Adryan Fristiohady
Borneo Journal of Pharmacy Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i1.694

Abstract

The aim of this study was to determine the characteristics of the gel formula based on it’s organoleptic properties, pH, viscosity, dispersion and homogenity by stability test carried out using the cycling test method and to determine the anti-inflammatory activity of the Xestospongia Sp. in male white mice (Mus musculus) by creating an artificial edema on the mice left foot induced by 1% λ-carrageenan. The gel formula from the ethanol extract of Xestospongia Sp. sponge was physically stable in terms of its organoleptic observation, homogenity, pH and viscosity test. However, the results that were obtained after dispersion test did not fulfill the requirements. In this study, the gel formula of the ethanol extract of Xestospongia Sp. sponge was administered on the mice left foot by using the variations in extract concentration of 0.02%, 0.03%, and 0.04%, and the gel without extract as a negative control and Galtaren®gel (1% Diclofenac Sodium) as a positive control. The evaluated data were in the form of mice leg edema volume measured based on its percent of inflammation and percent of inflammatory inhibition and observed for 360 minutes. The data were analyzed by using the Kruskal-Wallis test followed by the Mann-Whitney test with a confidence level of 95%. The results of this study showed that the gel formula of ethanol extract of Xestospongia Sp. sponge has an anti-inflammatory effect on each concentration and the formula that has a large anti-inflammatory effect was obtained at extract concentration of 0.04%.
Immunomodulator Activity of Effervescent Granule of Wualae Fruit (Etlingera elatior (Jack) R.M. Smith) Based on Specific Phagocytic Activity Adryan Fristiohady; Wa Ode Siti Zubaydah; Wahyuni Wahyuni; Mirda Mirda; Saripuddin Saripuddin; Rina Andriani; La Ode Muhammad Julian Purnama; Sahidin Sahidin
Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i2.868

Abstract

The previous study reported that Etlingera elatior (Wualae) has activity as immunostimulant with dose at 300 mg/kg BW and 400 mg/kg BW. Formulating natural product into effervescent granule (GE) can increase practicality and interest to consume traditional medicine. This study aims to investigate the immunostimulant activity of Wualae ethanolic extract in the effervescent granule. Wualae was macerated with ethanol then formulated into effervescent granule at dose 300 mg/kgBW and 400 mg/kgBW. Formulations were evaluated. Animals were divided into 4 groups and treated with: group I (positive control); group II (negative control); group III (GE dose at 300mg/kgBW); and group IV (GE at dose 400mg/kgBW) for 7 days and at days 8, groups were infected by Staphylococcus aureus intraperitoneally. Immunostimulant activity was measured by calculating the Specific Phagocytic Activity (SPA) of macrophage. Data collected from the evaluation and measurement of the SPA then analyzed using SPSS. Results from the evaluation were considered good except the moisture content of effervescent granule. Results from SPA was found that effervescent granule at dose 300 mg/kgBW and at dose 400 mg/kgBW have 26.33% and 32.5% consecutively with significance 0.02 (p<0.05). Thus, effervescent granule has comparable phagocytosis activity with positive control.
Level of Cytokine Interleukin-6 and Interleukin 1-β on Infectious Rat Model Treated with Etlingera elatior (Jack) R.M. Smith Fruit Extract as Immunomodulator Adryan Fristiohady; Wahyuni Wahyuni; Fadhliyah Malik; Muhammad Ilyas Yusuf; Wa Ode Salma; Rini Hamsidi; Fredy Talebong; Yuliansyah Yuliansyah; La Ode Muhammad Julian Purnama; Saripuddin Saripuddin; Sahidin Sahidin
Borneo Journal of Pharmacy Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i2.1318

Abstract

Etlingera elatior (Jack) R.M Smith or locally in Southeast Sulawesi known as Wualae fruit has activity as an immunomodulator by increasing phagocytosis activity. Prior studies have been conducted to observe the effect of E. elatior as an immunomodulator, thus further study is needed to observe the production of cytokines such as IL-1β and IL-6 which are responsible for the immune responses. Etlingera elatior fruit macerated with 96% ethanol for three days and produced a total of ±74.6 g concentrated extract. Experimental animals used were divided into four groups (n=4) and treated orally once a day for seven days as follows: group I (0.5% Na CMC); group II (Stimuno®); group III (E. elatior fruit extract dose of 300 mg/kg BW); and group IV (E. elatior fruit extract dose of 400 mg/kg BW). On the eight-day, animals were infected with Staphylococcus aureus intraperitoneally and left for an hour. Thereafter, blood was collected and assayed using ELISA Kit (Elabscience rat IL-1β and Elabscience rat IL-6). Results demonstrated that group IV increased levels of IL-1β and group III and IV increased level of IL-6 (p<0.05). Increased levels of IL-1β and IL-6 are associated with phagocytosis in the immune response. In conclusion, E. elatior fruit extract at doses of 300 and 400 mg/kg BW increases levels of IL-1β and IL-6.
The Effect of Quality Service Towards Outpatients Satisfaction at Poasia Community Health Centre Adryan Fristiohady; La Ode Muhammad Fitrawan; Yusniati Dwi Pemudi; Ruslin Ruslin; Sunandar Ihsan; Ruslan Ruslan; La Ode Muhammad Julian Purnama
Borneo Journal of Pharmacy Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i4.1611

Abstract

The quality of outpatient services can be measured by the SERVQUAL model that considers five dimensions: tangibles, reliability, responsiveness, assurance, and empathy. This study aimed to look at the effect of service quality on outpatient satisfaction at the Poasia community health center's pharmacy. The subjects in this study were 33 outpatients. The analysis technique used is gap analysis to compare patients' expectations and reality, normality test data based on questionnaire patient satisfaction tested for validation. This study's results indicate the average value of the gap in the Poasia community health center's pharmacy, amounting to -0.44. From the value of the gap, the lowest gap value in the pharmacy center of Poasia is the place of service and the provision of inadequate drug information of -0.88. Based on the paired t-test where a significant value >0.05, Ho is rejected, and Ha accepted, which means a significant difference between the quality of service and patients' satisfaction in the Pharmacy of Puskesmas Poasia Kendari City. This study concludes that there is a significant gap between expectations and reality at the Poasia community health center's pharmacy.
Total Phenolic and Flavonoid Content, Antioxidant, and Toxicity Test with BSLT of Meistera chinensis Fruit Fraction from Southeast Sulawesi Musdalipah Musdalipah; Selfyana Austin Tee; Karmilah Karmilah; Sahidin Sahidin; Adryan Fristiohady; Agung Wibawa Mahatva Yodha
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1686

Abstract

Zingiberaceae have a large number of species and still need research to reveal their chemical content. Meistera chinensis is one of the new generations of the Zingiberaceae family, a local and widespread plant in Konawe Regency, Southeast Sulawesi. Empirically, M. chinensis is used as a flavor enhancer in food, aches, and increases body immunity. There are no reports of chemical content or its biological activity. In this study, the fruit of M. chinensis was tested for phytochemicals, antioxidants using the ABTS test, total phenolic, total flavonoid content, and toxicity test with a lethal test for brine shrimp (BSLT). Meistera chinensis was extracted with ethanol and fractionated by ethyl acetate solvent using vacuum liquid chromatography. Phytochemical screening was carried out qualitatively by using the calorimetric method. The fraction toxicity was monitored by BSLT. These fractions for the ABTS method obtained fractions 1-8 (F1-F8) and ascorbic acid were used as controls. The results showed radical scavenging activities fraction of M. chinensis fruit was a very strong activity with IC50 of 42.7±3.53 mg/L (F8). The total phenolic and flavonoid contents were 30.72±1.07 mgGAE/g and 8.02±0.48 mgQE/g, respectively. The phytochemical evaluation contains terpenoids, saponins, phenolics, steroids, alkaloids, and flavonoids. The BSLT toxicity test was found to be very toxic, with an IC50 of 5.2±0.72 mg/L. These findings indicate that the fruit of M. chinensis acts as an antioxidant and toxicity agent.
Co-Authors Abdulkadir Kamaluddin Agung W. M. Yodha Andini Sundowo Arfan Arfan Asniar Pascayantri Astrid Indalifiany Bafadal, Mentarry Fadhliyah Malik Fitrawan, La Ode Muhammad Fredy Talebong Grasiana Eka E.Y.G Gusti Ray Sadimantara Idin Sahidin Ilma Mustaqima Rianse Intan Permata Putri Iren Meylani Karmilah Karmilah La Ode Muhammad Julian Purnama Laode Muhamad Mbuyang Nadia M. Hajrul Malaka Marianti A. Manggau Masrika, Nur Upik En Mirda Mirda Muh. Azdar Setiawan Muhamad Handoyo Sahumena Muhammad Hajrul Malaka Muhammad Ilyas Yusuf Muhammad Ilyas Yusuf Muktiarni, Muktiarni Musdalipah Musdalipah N. Nohong Nita Trinovitasari Nur Indri Rahayu Nur Saadah Daud Nur Syifa Rahmatika Nurwati Nurwati Rathapon Asasutjarit Rifa'atul Mahmudah Rina Andriani Rina Maryanti Rini Hamsidi Ruslan Ruslan Ruslin Ruslin Sahidin Sahidin Sahidin Saripuddin Saripuddin Selfyana Austin Tee Sernita Sernita Sofa Fajriah Sunandar Ihsan Tian Amalia Halik Wa Kuasa Baka Wa Ode Norma Wa Ode Salma Wa Ode Siti Zubaydah Wa Ode Sitti Zubaydah WAHYUNI Wahyuni Wahyuni Yamin Yamin Yodha, Agung Wibawa Mahatva Yuliansyah Yuliansyah Yulianti Fauziah Yusniati Dwi Pemudi