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Meity M Laut
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Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Public Health Veterinary

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Resistensi Larva Strongyle sp. Terhadap Albendazole pada Kambing Kacang (Capra hircus) di Indonesia Natasha Imanuelle; Meity M Laut; Dede Rival Novian
Jurnal Veteriner Nusantara Vol 6 No 1 (2023): Februari 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i1.2791

Abstract

Nematodiasis is a disease of livestock which caused by nematode infestation. Nematodes in the digestive tract inhibit livestock productivity and increase mortality in young animal. Generally speaking, control of nematodiasis is done by administering anthelmintic from benzimidazole group. Albendazole is the most commonly used anthelmintic. However, continuous use of albendazole in ruminants leads to the development of resistance. The present study aims to not only investigate and evaluate Strongyle sp. larvae resistance to albendazole in Indonesia but also to determine the incident rate of albendazole resistance. This study and references were obtained through Google Scholar and PubMed then arranged using Mendeley. The references are scientific journals, scientific articles, Ebooks and proceedings with "keywords" resistance of Strongyle sp. larvae to albendazole. All references were analyzed and evaluated systematically. The result show that the resistence of Strongyle larvae against albendazole occurred in West Java, East Java, and Yogyakarta with the results of the resistence test was 67%to 89%; 77% and 83%. This results shows that the ability of the drug to treat nematodiasis is no longer optimal. The risk factors of strongyle larvae resistence to albendazole are administering sntihelmintic from the same group continously with inapropriate dose and the ability of worms to develop resistence genes against albendazole.
Studi Kepustakan Uji Sensitivitas Antibiotik terhadap Escherichia coli Isolat Kecoak Monycha Bumbungan; Meity M Laut; Novalino H. G. Kallau
Jurnal Veteriner Nusantara Vol 5 No 1 (2022): Februari 2022
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v5i1.2987

Abstract

Kecoak merupakan vektor mekanis yang hidup berdampingan dengan manusia. Kecoak bertindak sebagai vektor karena terkait erat dengan keberadaan bakteri yang dibawa pada permukaan tubuhnya. Escherichia coli adalah bakteri yang tersebar di lingkungan yang dapat mengkontaminasi air dan tanah disekitarnya sehingga dapat disebarkan melalui vektor seperti kecoak. Penelitian ini bertujuan untuk mengetahui prevalensi Escherichia coli isolat kecoak dan profil uji sensitivitasnya terhadap antibiotik. Penelitian ini menggunakan pendekatan studi kepustakaan dengan melakukan penelusuran dan pengumpulan informasi dan data dari data base Google Cendekia. Data dan informasi dianalisis secara deskriptif dan dibahas berdasarkan hasil penelitian dari berbagai sumber. Hasil studi kepustakaan menunjukkan 100% (7/7) literatur penelitian dapat mengisolasi Escherichia coli dari tubuh kecoak dengan prevalensi rata-rata Escherichia coli 40,22%. Hasil uji sensitivitas beberapa literatur penelitian menunjukkan Escherichia coli isolat kecoak telah resisten terhadap antibiotik ampicillin, piperacillin, amoxicillin, penicillin, cloxacilin, ceftriaxone, cefuroxime, cephotaxime, cefepime, ceftazidime, erythromycin, gentamycin, streptomycin, amikacin, nalidixic acid, ciprofloxacin, ofloxacin, tetracycline, chloramphenicol dan vancomycin. Beberapa literatur penelitian juga melaporkan Escherichia coli isolat kecoak masih sensitif terhadap antbiotik vancomycin, ciprofloxacin, ofloxacin, imipenem, cefoperazone, gentamycin, ampicillin, methylaxone, tetracycline, chloramphenicol dan erythromycin.
Efektifitas Ekstrak Serai Dapur (Cymbopogon citratus) Sebagai Larvasida Nyamuk Culex Sp di Kota Kupang Agatha Sada Ua; Julianty Almet; Meity M Laut
Jurnal Veteriner Nusantara Vol 6 No 1 (2023): Februari 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i1.3022

Abstract

Beberapa penyakit disebabkan oleh nyamuk sebagai vektor, seperti demam berdarah dengue (DBD), malaria dan filariasis. Kota Kupang pada tahun 2018, terdapat 238 kasus DBD dan 35 kasus malaria. Berbagai upaya dilakukan untuk memutuskan siklus hidup nyamuk, salah satunya dengan menggunakan larvasida. Salah satu tanaman yang dapat digunakan sebagai larvasida adalah serai dapur (Cymbopogon citratus). Penelitian ini bertujuan untuk mengetahui nilai Lethal Concentration 50 (LC50) dari ekstrak serai dapur (Cymbopogon citratus). Pengujian ekstrak serai dapur (Cymbopogon citratus) sebagai larvasida dilakukan dengan menggunakan 25 ekor larva Culex sp pada setiap perlakuan dan diuji pada enam konsentrasi yaitu 0%; 0,2%; 0,4%; 0,6%; 0,8% dan 1% serta dilakukan pengulangan sebanyak tiga kali dan dilakukan pengamatan pada 2 jam, 4 jam, 12 jam dan 24 jam. Hasil penelitian menunjukkan kematian larva sebesar 5,3% (0%); 45,3% (0,2%); 70,6% 0,4%; 96% (0,6%); 100% (0,8% dan 1%). Hasil analisis probit menunjukkan nilai LC50 sebesar 0,412%, sehingga dapat disimpulkan bahwa ekstrak serai dapur (Cymbopogon citratus) efektif sebagai larvasida nyamuk Culex sp dan pada konsentrasi 0,412% ekstrak serai dapur (Cymbopogon citratus) mampu membunuh 50% dari jumlah larva uji.Salah satu tanaman yang dapat digunakan sebagai larvasida adalah serai dapur (Cymbopogon citratus). Penelitian ini bertujuan untuk mengetahui nilai Lethal Concentration 50 (LC50) dari ekstrak serai dapur (Cymbopogon citratus). Pengujian ekstrak serai dapur (Cymbopogon citratus) sebagai larvasida dilakukan dengan menggunakan 25 ekor larva Culex sp pada setiap perlakuan dan diuji pada enam konsentrasi yaitu 0%; 0,2%; 0,4%; 0,6%; 0,8% dan 1% serta dilakukan pengulangan sebanyak tiga kali dan dilakukan pengamatan pada 2 jam, 4 jam, 12 jam dan 24 jam. Hasil analisis probit menunjukkan nilai LC50 sebesar 0,412%, sehingga dapat disimpulkan bahwa ekstrak serai dapur (Cymbopogon citratus) efektif sebagai larvasida nyamuk Culex sp dan pada konsentrasi 0,412% ekstrak serai dapur (Cymbopogon citratus) mampu membunuh 50% dari jumlah larva uji.
Kajian Escherichia coli Resisten Antibiotik pada Lingkungan Air di Indonesia Yudith Elma Mauwalan; Novalino Kallau; Meity M Laut
Jurnal Veteriner Nusantara Vol 5 No 1 (2022): Februari 2022
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v5i1.3264

Abstract

Water is a natural resource that is needed by living things. Esherichia coli is one of the normal flora on digestive tract of humans and animals and is a parameter of drinking water quality because its presence in the water indicates the water is contaminated. Esherichia coli is abundant in water and is a reservoir associated with Antimicrobial Resistance (AMR). This literature review aims to determine the prevalence level of Escherichia coli in the water environment in Indonesia and the level of Escherichia coli resistant to β-lactam antibiotics and aminoglycoside antibiotics. This literature review is obtained from searching and collecting data and information from various reference sources using the Mendeley and Google Schoolar applications. Research data on Escherichia coli resistance were analyzed and evaluated and it was found that the prevalence of Escherichia coli in the water environment in Indonesia ranges from 33.33% to 100% and the level of antibiotic resistance in the β-lactam group (Amoxicillin 66.7%-100%, Ampicillin 100% and Penicillin 100%) and Aminoglycosides (Streptomycin 73.3%-86.7%, Tobramycin 100%, Gentamicin 100% and Kanamycin 33.3%) against Escherichia coli in the water resources in Indonesia.
Studi Literatur Uji Aktivitas Ekstrak Daun Kirinyuh (Chromolaena odorata) Sebagai Alternatif Pengobatan Myiasis yang Disebabkan oleh Chrysomya bezziana Diana Rabeka Otu; Nemay A Ndaong; Meity M Laut
Jurnal Veteriner Nusantara Vol 6 No 1 (2023): Februari 2023
Publisher : Program Studi Kedokteran Hewan, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jvn.v6i1.5370

Abstract

Myiasis is a disease in livestock caused by the larvae of the fly Chrysomya bezziana . Myiasis causes economic losses due to decreased productivity and tissue damage in livestock. Treatment of myiasis is by using synthetic insecticides, but the use of synthetic insecticides has a negative impact on animals, humans, and the environment. The use of synthetic insecticides can be replaced with botanical insecticides, one of the plants that can be used as antimyiasis is kirinyuh . Kirinyuh is a plant from the Asteraceae family which has been used as a botanical insecticide. This literature study aims to determine the potential of kirinyuh leaves as antimyiasis, the compounds contained in kirinyuh leaves and the mechanism of antimyiasis. This literature study uses 30 literature collected by browsing the Google Scholar database. Five literature states that kirinyuh leaves contain secondary metabolites of flavonoids, alkaloids, saponins, tannins and terpenoids. Meanwhile, 12 literatures describe the antimyiasis activity of these secondary metabolites. Flavonoids inhibit the nervous system and interfere with energy metabolism in the insect body, alkaloids interfere with the nervous system and reduce insect appetite, saponins as antifeedants and insect growth inhibitors, tannins interfere with insect digestion and growth, and terpenoids as inhibitors of nerve transmission in insects.
Co-Authors Agatha Sada Ua Diana Rabeka Otu Julianty Almet Kallau, Novalino Harold Geoffrey Monycha Bumbungan Natasha Imanuelle Nemay A Ndaong Novian, Dede Rival Yudith Elma Mauwalan