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DAYA ANTIBAKTERI EKSTRAK ETANOL BUAH PACE (Morinda citrifolia, L) TERHADAP BAKTERI Shigella dysentriae SECARA IN VITRO SERTA PROFIL KROMATOGRAFI LAPIS TIPIS Nurcahyani, Diah
Widya Warta No. 02 Tahun XL/Juli 2016
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Pace fruit (Morinda citrifolia, L) is known by people as an ingredient of beverage. In addition, the people take it as medicine for dysentery. It was carried out a study with the intention of observing the antibacterial activity of extract of pace fruit, on bacteria Shigella dysentriae. The dried fruit was pounded to powder then a filtering was made employing Soxhlet, with ethanol as the extractor. The extract had been obtained was then evaporated to achieve viscosity and it was made a serial of dilution in various concentration, namely, 2,5%, 5%, 10%, and 20% b/v by propilen glikol solvent and an examination was performed for the activity of antibacterial involved. To negative control it was used propilen glikol and while positive control it was used kanamizi. Bacteria used was Shigella dysentriae. The examination adapted the method of Nutrient gel solid diphusy to see Minimal Obstacle Rate (Kadar Hambat Minimal). The outcome of antibacterial test showed that the extract of pace demonstrated antibacterial activity on Shigella dysentriae, at a minimal obstacle rate 20% b/v. To see the chemical content of pace fruit, it was performed thin chromatography on the extract of pace fruit to observe the profile of spots involved. The outcome of examination for the content of compound under ultra violet ray 254 nm and 366 nm, showed that the extract of pace was possibly containing fenol compound.
PENGARUH KAPSUL EKSTRAK TEMULAWAK (Curcuma xanthorrhiza Roxb.) TERHADAP KADAR LDL DAN HDL KOLESTEROL PADA MENCIT HIPERLIPIDEMIA Nurcahyani, Diah
Widya Warta No. 01 Tahun XLIII/Januari 2019
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Hyperlipidemia is an increase in blood lipid levels. Hyperlipidemia is strongly associated with changes in HDL levels and increases in LDL levels. One alternative natural ingredient to  reduce cholesterol levels in the blood is ginger (Curcuma xanthorrhizaRoxb.). The purpose of this study was to determine the effect of capsules of temulawak extract (Curcuma xanthorrhizaRoxb.) on decreasing LDL and HDL cholesterol levels in hyperlipidemic mice. This study used 12 mice (Mus musculus L.). Models of hyperlipidemia animals were made with induction of egg yolk for 7 days. Therapy was carried out for 7 days with a curcuma xanthorrhizaRoxb extract capsule of 3x0.2 ml / day and 3x0.4 ml / day. The analysis used in this study is the One Way Analysis of Variance (ANOVA) with Duncan's advanced test for LDL and HDL levels. The results of the data analysis can be concluded that the curcuma xanthorrhizaRoxb Extract capsule significantly reduced LDL levels and significantly increased HDL levels in hyperlipidemic mice (Mus musculus L.).
ANALISIS MUTU PELAYANAN PETUGAS FARMASI DAN KETERSEDIAAN OBAT TERHADAP KEPUASAN PASIEN RAWAT JALAN DI RS SANTA CLARA MADIUN TAHUN 2019 Nurcahyani, Diah; Kartikaningrum, Vidya
Widya Warta No. 02 Tahun XLIII/Juli 2019
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Service quality, pharmaceutical providers, and the availability of medicines determine the outpatients’ satisfaction in the Department of Hospital Pharmaceutical Installation (IFRS). The phenomena, found in RS Santa Clara Madiun, are that and patients usually wait too long to get medicines, and the presence of empty drugs. The objective of the research was to find out the influence of the service quality pharmaceutical providers and the availability of medicines on the outpatients’ satisfaction in RS Santa Clara, in June 2019h . The research was a cross sectional method on 100 outpatients, using accidental sampling technique. The data were gathered by using questionnaires and analyzed by using bilinear regression test (α= 0,05). The result of the research showed that the variables of pharmaceutical providers and the availability of medicines influenced patients’ satisfaction (p < 0.005). The variable of the availability of medicines had the most dominant influence on outpatients’ satisfaction at the coefficient value of (β) 0.853). It is recommended that the management of RS Santa Clara Madiun furnish the availability of medicines and the facility of the IFRS waiting rooms, and pharmaceutical providers increase the dimension of the guarantee in order to improve the performance of the pharmaceutical providers and the information service about medicines.
ANALISIS MUTU PELAYANAN PETUGAS FARMASI DAN KETERSEDIAAN OBAT TERHADAP KEPUASAN PASIEN RAWAT JALAN DI RS SANTA CLARA MADIUN TAHUN 2019 Diah Nurcahyani; Vidya Kartikaningrum
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.135 KB) | DOI: 10.36387/jiis.v5i1.384

Abstract

Service quality, pharmaceutical providers, and the availability of medicines determine the outpatients’ satisfaction in the Department of Hospital Pharmaceutical Installation (IFRS). The phenomena, found in RS Santa Clara Madiun, are that and patients usually wait too long to get medicines, and the presence of empty drugs. The objective of the research was to find out the influence of the service quality pharmaceutical providers and the availability of medicines on the outpatients’ satisfaction in RS Santa Clara, in June 2019. The research was an cross sectional method on 100 outpatients, using accidental sampling technique. The data were gathered by using questionnaires and analyzed by using bilinear regression test (α= 0,05). The result of the research showed that the variables of pharmaceutical providers and the availability of medicines influenced patients’ satisfaction (p < 0.005). The variable of the availability of medicines had the most dominant influence on outpatients’ satisfaction at the coefficient value of (β) 0.853).
PENGENALAN DAGUSIBU OBAT BERSAMA PKK KELURAHAN/KECAMATAN KARANGREJO KABUPATEN MAGETAN Diah Nurcahyani; Vidya Kartikaningrum; Andita Nur W; Cristina Indrasari
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Knowledge of medicine is a must for all levels of society. DAGUSIBU is one of those attempts to increase public knowledge in using and managing drugs amidst the widespread of counterfeit drugs and drugs abuse. The purpose of this community service is to provide DAGUSIBU counseling to the community, especially PKK in the Karangrejo Sub-district, Magetan Regency. This counseling is expected to increase knowledge of the use of drugs. Participants in this counseling were given material about DAGUSIBU directly and supported by teaching aids in the form of medicine as an example of the application of DAGUSIBU in active discussion. The result achieved is the increase in this counseling participants about drugs through DAGUSIBU by 44.31% from 46.27 to 90.59 forming DAGUSIBU cadres in the community. Therefore, this counseling needs to be continued to improve cadres as quality information agents to the general public, especially in the Karangrejo Sub-district, Magetan Regency.
The Effect of Curcuma (Curcuma xanthorrhiza Roxb.) Extract Capsule Treatment on Mice Blood Glucose Level: Pengaruh Pemberian Kapsul Ekstrak Temulawak (Curcuma xanthorrhiza Roxb.) terhadap Kadar Glukosa Darah pada Mencit Diah Nurcahyani
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 7 No. 2 (2022): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v7i2.280

Abstract

Diabetes melitus is a metabolic disorder with escalating blood glucose level (hyperglycemic) symptom. One of endemic plant in Indonesia which have antidiabetic properties potency is curcuma. This background leads to this research that was conducted to determines the effect of various curcuma extract capsule dose treatment to lowering mice blood glucose. This research was used glucose induced mice that were grouped into three groups: Group I (Negative control) aqua destilata treated group, Group II (Dose 1) curcuma extract capsule dose 18 mg/kgBW treated group, and Group III (Dose 2) curcuma extract capsule dose 20 mg/kgBW treated group. After 7 days of treatment, blood glucose level negative control group is 185 mg/dl, curcuma extract capsule dose 1 is 123 mg/dl, and dose 2 is 101 mg/dl. Curcuma extract capsule treated groups showed significant different blood glucose level with negative control treated group. This could be concluded that curcuma extract capsule has effect as antihyperglycemic on glucose 5% induced mice.
Pengembangan Obat Tradisional Menjadi Produk Permen Bersama PKK Kelurahan/Kecamatan Karangrejo Kabupaten Magetan Bida Cincin Kirana; Antonius Budiawan; Levi Puradewa; Vidya Kartikaningrum; Diah Nurcahyani; Erlien Dwi Cahyani; Maria Fatmadewi Imawati; Christina Indriasari; Andita Nur Wijayanti
Jompa Abdi: Jurnal Pengabdian Masyarakat Vol. 1 No. 4 (2022): Jompa Abdi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jompaabdi.v1i4.297

Abstract

Tahun 2021 telah dilaksanakan program pengabdian kepada masyarakat bekerjasama dengan PKK di lingkungan Kelurahan/Kecamatan Karangrejo Kabupaten Magetan, melalui kegiatan edukasi dan pelatihan pemanfaatan tanaman obat untuk meningkatkan daya tahan tubuh serta membuat produk jamu instan. Produk sediaan yang mudah untuk dibuat selain jamu instan adalah permen. Obat tradisional dalam bentuk permen memiliki keunggulan dalam bentuk yang menarik, dan bahan bakunya mudah diperoleh serta dapat dijadikan cemilan. Kegiatan ini bertujuan untuk meningkatkan pengetahuan mitra mengenai pemanfaatan tanaman krokot dan limbah kulit buah semangka sebagai obat tradisional serta meningkatkan keterampilan mitra dalam pengolahan obat tradisional menjadi produk permen yang memiliki nilai ekonomis. Kegiatan pengabdian kepada masyarakat ini dilakukan melalui edukasi pemanfaatan krokot dan kulit buah semangka sebagai obat tradisional dan pelatihan pembuatan permen obat tradisional. Hasil dari pengabdian ini adalah mitra dalam hal ini PKK Kelurahan Karangrejo, Kecamatan Karangrejo, Kabupaten Magetan yang mengikuti pelatihan, sebagian besar dapat membuat permen obat tradisional berdasarkan formula yang telah diberikan. Pengetahuan mitra tentang obat tradisional, manfaat kulit buah semangka dan herba krokot sebagai obat tradisional meningkat sebesar 14,58 dari 84,38 menjadi 98,96 setelah mengikuti pelatihan.
PENGENALAN DAGUSIBU OBAT BERSAMA PKK KELURAHAN/KECAMATAN KARANGREJO KABUPATEN MAGETAN Diah Nurcahyani; Vidya Kartikaningrum; Andita Nur W; Cristina Indrasari
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jbn.v2i2.958

Abstract

Knowledge of medicine is a must for all levels of society. DAGUSIBU is one of those attempts to increase public knowledge in using and managing drugs amidst the widespread of counterfeit drugs and drugs abuse. The purpose of this community service is to provide DAGUSIBU counseling to the community, especially PKK in the Karangrejo Sub-district, Magetan Regency. This counseling is expected to increase knowledge of the use of drugs. Participants in this counseling were given material about DAGUSIBU directly and supported by teaching aids in the form of medicine as an example of the application of DAGUSIBU in active discussion. The result achieved is the increase in this counseling participants about drugs through DAGUSIBU by 44.31% from 46.27 to 90.59 forming DAGUSIBU cadres in the community. Therefore, this counseling needs to be continued to improve cadres as quality information agents to the general public, especially in the Karangrejo Sub-district, Magetan Regency.
PENYEBAB OBAT KEDALUARSA, OBAT RUSAK DAN DEAD STOCK (STOK MATI) DI GUDANG PERBEKALAN FARMASI GUDANG PERBEKALAN FARMASI RUMAH SAKIT X SURABAYA Diah Nurcahyani; Arina Ayuningtyas; Leo Eladisa G
Jurnal Riset Kefarmasian Indonesia Vol 5 No 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.353

Abstract

Drug processing problems in each hospital often occur nowadays, so it is necessary to carry out continuous evaluation to create optimal services in providing good quality patient health. This study aims to describe and analyze the occurrence of expired drugs, damaged drugs and dead stock, to provide policy recommendations for improving drug processing. This study uses a descriptive method, namely research that describes an object in relation to the actual situation. The sample used in this study is the number of expired drugs, damaged drugs and dead stock for the period June - August 2021 compared to the total number of drugs in the hospital. The percentage results for expired drugs were 0.002%, damaged drugs were 0%, dead stock were 0.022%, this was due to changes in prescribing patterns, expiration dates that were too short when receiving drugs from PBF and not maximally checking expired drugs in each unit, so it is necessary to do checking between planning and drug needs as well as improving the ED drug processing system and evaluating the system and evaluating the drug acceptance system in hospitals.
Manajemen Penyimpanan Obat Di Gudang Perbekalan Farmasi Rumah Sakit X Surabaya Dopy G; Diah Nurcahyani
An-Najat Vol. 1 No. 2 (2023): MEI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v1i2.26

Abstract

Obat wajib dikelola dengan baik dan benar karena merupakan aset yang berharga untuk memenuhi pelayanan kesehatan dengan jenis dan jumlah yang sesuai. Obat wajib dikelola dengan baik dan benar karena merupakan aset yang berharga untuk memenuhi pelayanan kesehatan dengan jenis dan jumlah yang sesuai. Pencatatan transaksi keluar-masuk obat harus dilaksanakan dalam proses penyimpanan obat. Sistem pencatatan obat di kartu stok yang efektif dapat mengurangi kejadian tak diingikan dan kejadian tak diharapkan. Dua dari empat indikator efisiensi penyimpanan obat adalah kesesuaian tanggal kadaluwarsa, nomor bets antara obat dan kartu stok. Nomor bets diperlukan ketika produk mengalami kualitas substandar. Penelitian ini bertujuan untuk mengetahui sistem penyimpanan obat di gudang perbekalan farmasi Rumah Sakit X Surabaya dengan parameter dari peraturan BPOM juga untuk mengetahui persentase kesesuaian tanggal kadaluwarsa dan nomor bets antara obat dan kartu stok sebagai manifestasi dari prinsip penyimpanan obat serta penyebabnya. Penelitian ini adalah penelitian deskriptif kualitatif dengan sumber data primer dan sekunder. Pengumpulan data yang dilakukan secara observatif langung menggunakan ceklis berdasarkan peraturan BPOM no 4 tahun 2018. Data sekunder diperoleh melalui observasi dan rekapitulasi hasil stok opname tahun 2020 dan 2021 untuk menghasilkanketidaksesuaian tanggal kadaluwarsa dan nomor bets. Penelitian ini menggunakan total sampling seluruh obat dan sistem penyimpanan di gudang. Dari hasil penelitian penyimpanan obat Gudang Perbekalan Farmasi Rumah Sakit X Surabaya memperolehhasil sangat baik berdasarkan penilaian Arikunto (2013) dengan persentase 88%. Ketidaksesuaian nomor bets dan tanggal kadaluwarsa berturut-turut 18,8% dan 6,42% nilai tersebut tidak memenuhi standar indikator Pudjaningsih (1996). Penyebabketidaksesuaian nomor bets dan tanggal kadaluwarsa adalah beban kerja yang naik sepanjang tahun 2021