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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Kedokteran Syiah Kuala Berkala Kedokteran The Indonesian Biomedical Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Panrita Abdi - Jurnal Pengabdian pada Masyarakat Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Acta Biochimica Indonesiana Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Jurnal Pengabdian Kesehatan Komunitas (Journal Of Community Health Service) Engagement: Jurnal Pengabdian Kepada Masyarakat Prosiding Seminar Nasional Unimus

Siregar, Fajri Marindra

Department Of Biochemistry, Faculty Of Medicine, Universitas Riau, Pekanbaru, Indonesia

Author-ID : 958586

Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Gambaran Keterampilan Teknologi Informasi Mahasiswa di Fakultas Kedokteran Universitas Riau afdhal cahya pratama; Zahtamal Zahtamal; Fajri Marindra Siregar
Jurnal Ilmu Kedokteran Vol 14, No 2 (2020): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v14i2.2020.94-102

Information technology is a general term that describes any technology that assists humans in creating, modifying, storing, communicating funds or disseminating information. Information technology is useful in the field of education, it can especially help support the lecture process at the Faculty of Medicine. The purpose of this study was to describe the information technology skills of students at the Faculty of Medicine, Universitas Riau. The type of this research is a descriptive research. The research data is the result of the observation of students in class 2017, 2018 and 2019, totaling 126 students by researchers through a number of tests. The result of this study showed that information technology skills in the use of email at the Faculty of Medicine, Universitas Riau were the most mastered, while information technology skills in the use of number processing software, especially Microsoft Excel, were the most unmastered by students.

Immunosenescence : Penuaan Pada Sel Makrofag Fajri Marindra Siregar
Jurnal Ilmu Kedokteran Vol 13, No 1 (2019): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Immune function will decrease with age. The weakening of immune system is known as immunosenescence. Macrophages that play a major role in carrying out innate and adaptive immune functions have potential to undergo aging (macrophaging). Some potential mechanisms that can affect the aging of macrophages include telomere shortening, oxidative damage and impaired DNA repair processes. The impact of macrophaging can be a decrease number of macrophages in bone marrow, changing cytokine secretion, decreasing class II MHC expression, changing macrophages polarization, decreasing ability of phagocytosis, and decreasing ability of wound repair and tissue regeneration.

KORELASI ANTARA PANJANG TULANG STERNUM DENGAN TINGGI BADAN BERDASARKAN JENIS KELAMIN PADA RAS MONGOLOID USIA 18-45 TAHUN DI PROVINSI RIAU Dedi Afandi; Khodijah Khodijah; Fajri Marindra Siregar; Maysarah Elnas
Jurnal Kedokteran Syiah Kuala Vol 19, No 2 (2019): Volume 19 Nomor 2 Agustus 2019
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v19i2.18062

Abstrak. Penentuan tinggi badan memiliki peran penting dalam menentukan identitas personal pada kasus penemuan jenazah yang tubuhnya sudah tidak utuh lagi. Perkiraan tinggi badan pada jenazah yang tidak utuh dapat diketahui dengan mengukur panjang bagian tubuh tertentu dari jenazah tersebut, salah satunya adalah panjang tulang sternum. Tujuan penelitian ini adalah untuk mengetahui korelasi dan menentukan rumus perkiraan tinggi badan berdasarkan jenis kelamin menggunakan panjang tulang sternum. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Untuk mengetahui korelasi dan menentukan rumus regresi linier dilakukan uji statistik dengan menggunakan software IBM SPSS 26.0. Pada penelitian ini dilakukan pengukuran tinggi badan dan panjang tulang sternum pada 230 responden (115 pria dan 115 wanita) yang berusia 18-45 tahun di Provinsi Riau. Didapatkan korelasi bermakna antara panjang tulang sternum dengan tinggi badan (p0,01) pada responden pria dan wanita. Nilai koefisien korelasi pada responden pria (r = 0,33) dan wanita (r = 0,24) menunjukkan kekuatan korelasi lemah. Rumus regresi tinggi badan pada pria didapatkan yaitu: TB = 144,35 + 1,13(PS) ± 6,44 cm dan pada wanita: TB = 139,20 + 0,96(PS) ± 4,87 cm. Hasil penelitian ini menunjukkan bahwa panjang tulang sternum memiliki nilai forensik terbatas dan keandalan yang relatif rendah dalam memperkirakan tinggi badan manusia.Kata Kunci: Identifikasi, sternum, tinggi badan, korelasi, formula regresiAbstract. The determination of body height possesses a great and important role in establishing personal identities when founding an incomplete human corpse. The estimation of body height can be determined by measuring certain parts of the body, one of which is the length of the sternal bone. The purpose of this study was to understand the correlation and determining the approximate height equation based on sex using the sternal length. An analytical study with a cross-sectional approach was used in this research. To perceiving the correlation and determining the linear regression formula, a statistical test was performed using IBM SPSS 26.0. In this study, height measurement and the sternal length were recorded from 230 respondents (115 males and 115 females), aged between 18-45 years old in Riau Province. A significant correlation was obtained between sternal length and body height (p 0,01) in male and female respondents. The correlation coefficient (r) score for male (r = 0,33) and female (r = 0,24) respondents indicates a weak correlation strength. Height regression formula in men is obtained, namely: Body Height = 144,35 + 1,13(Sternal Length) ± 6,44 cm and in women: Body Height = 139,20 + 0,96(Sternal length) ± 4,87 cm. The result of this study shows that the length of the sternum bone has limited forensic value and relatively low reliability in estimating human height.Keywords: Identification, sternum, height, correlation, regression formula

Correlation between Dimension of Fingers Phalannx Proximal and Height in the Age of 18-45 Years Old Talitha Lailatul Hafizah; Dedi Afandi; Chunin Widyaningsih; Fajri Marindra Siregar
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Height is one of the data needed in forensic identification process of a remains that is difficult to identify in an incomplete condition. Height estimation can be determined by the proximal phalanx of the fingers which are long bones. This study was conducted on 113 men and 125 women in several places in Riau Province age 18 - 45 years. The height and dimensions of the proximal phalanx of the fingers are measured to get the correlation and linear regression formula for height. There are 6 dimensions measured on the fingers of the left and right hand. The study design was cross sectional. The statistical test used is Pearson correlation to determine the correlation between dimensions of the proximal phalanx on fingers with height and linear regression analysis for height regression formula. The results show that some dimensions of the proximal phalanx of the fingers are significantly correlated with height. Keywords: identification, height, dimensions of the proximal phalanx bone fingers, correlation, regression formula.

Negative Correlation between Cytoglobin Expression and Intracellular ROS Levels in Human Skin Keloid Fibroblasts Fajri Marindra Siregar; Novi Silvia Hardiany; Sri Widia Azraki Jusman
The Indonesian Biomedical Journal Vol 11, No 1 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i1.488

BACKGROUND: In our previous study, we found higher cytoglobin (Cygb) expression in keloid than normal tissue. Cytoglobin is a new globin family protein which function is still being studied to date. The purpose of this research is to elucidate the function of Cygb in human skin keloid fibroblasts (KFs), especially its role in intracellular reactive oxygen species (ROS) levels.METHODS: The study was conducted on human skin KFs obtained from primary culture. Inhibition of Cygb expression was achieved by using siRNA targeting Cygb. We compared the relative expression of Cygb between treatment and control group, and its effect on intracellular ROS levels. Gene expression was measured using quantitative real-time polymerase chain reaction (qRT-PCR) while the ROS level counted by dichlorodihydrofluorescein diacetate (DCFHDA) assay.RESULTS: There was an increase in intracellular ROS levels in the small interfering RNA (siRNA) (+) Cygb group compared to control group (1.673 vs. 1.260; 1.773 vs. 1.393; 1.710 vs. 1.360; respectively). There is a negative correlation between Cygb expression and ROS level (p<0.05; r=-0.651).CONCLUSION: There is a negative correlation between Cygb expression and intracellular ROS levels, we suggest Cygb acts as a ROS scavenger in human skin KFs.KEYWORDS: skin keloid fibroblasts, cytoglobin, siRNA, ROS

Identifikasi gen kariogenik glukosiltransferase Streptococcus mutans pada pasien karies gigiIdentification of Streptococcus mutans cariogenic gene glucosyltransferase (gtf) in dental caries patients Rita Endriani; Fajri Marindra Siregar; Elita Rafni; Rahmat Kemal Azhari; Jefrizal Jefrizal
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 33, No 1 (2021): April 2021
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v33i1.30397

Pendahuluan: Streptococcus mutans (S. mutans) merupakan bakteri yang mempunyai glukosiltransferase surface (GTFs) yang berperan pada proses perlekatan dan virulensi bakteri pada permukaan gigi. Enzim GTFs terdiri atas tiga jenis enzim GTFs yaitu GTFB, GTFC dan GTFD dan masing-masing enzim ini dikode oleh gen gtfB, gtfC dan gtfD yang juga berperan sebagai prekursor dalam adhesi seluler plak gigi yang dapat menyebabkan karies gigi. Tujuan penelitian adalah mengidentifikasi gen gtfC dan gtfD S. mutans pada pasien karies gigi. Metode: Penelitian dilakukan dengan consecutive sampling. Sampel penelitian diambil dari kerokan jaringan karies gigi, diisolasi, dikultur, dan diidentifikasi di laboratorium Mikrobiologi dan Sentral FK UNRI. Identifikasi S. mutans dan gen kariogenik gtfC dan gtfD menggunakan metode Polymerase Chain Reaction (PCR). Data ditampilkan dalam bentuk tabel distribusi frekuensi dan dinyatakan dalam persentase Hasil: Dari 60 kerokan jaringan karies didapatkan S. mutans sebanyak 10 isolat, sedangkan gen gtfC dan gen gtfD didapatkan masing-masing 4 (40%) isolat. Simpulan: Gen kariogenik teridentifikasi gen gtfC dan gtfD pada isolat S. mutans dari pasien karies gigi sebanyak 40%.Kata kunci: gtfC, gtfD, kariogenik glukosiltransferase Streptococcus mutans. ABSTRACTIntroduction: Streptococcus mutans (S. mutans) is a bacterium with a glucosyltransferase (Gtfs) surface, which plays a role in the attachment process and bacteria virulence on the tooth surface. The Gtfs enzyme consists of three types of Gtfs enzymes, namely GtfB, GtfC, and GtfD. These enzymes are encoded by the GtfB, GtfC, and GtfD genes, which also act as precursors in the cellular adhesion of dental plaque that can cause dental caries. This study was aimed to identify the GtfC and GtfD of S. mutans in dental caries patients. Methods: This study was conducted with consecutive sampling. Research samples were taken from dental caries tissue scrapings, isolated, cultured, and identified in the Microbiology and Central Laboratory of the Faculty of Medicine University of Riau. Identification of S. mutans and GtfC and GtfD cariogenic genes using the Polymerase Chain Reaction (PCR) method. The data was displayed in the form of a frequency distribution table and expressed as a percentage. Results: From 60 caries tissue scrapings, ten isolates were obtained, while the GtfC gene and GtfD gene were obtained 4 (40%) isolates each. Conclusion: Forty percents of S. mutans isolates from dental caries patients were identified as the GtfC and GtfD cariogenic genes.Keywords: GtfC, GtfD, cariogenic, Streptococcus mutans glucosyltransferase.

SEMINAR AWAM BAHAYA SINDROMA METABOLIK DAN CARA PENCEGAHANNYA DI KOTA SIAK SRI INDERAPURA, KABUPATEN SIAK, RIAU Fajri Marindra Siregar; Hendra Asputra; Mukhyarjon; Imelda Tresia Pardede
Panrita Abdi - Jurnal Pengabdian pada Masyarakat Vol. 5 No. 1 (2021): Jurnal Panrita Abdi - Januari 2021
Publisher : LP2M Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/pa.v5i1.7847

Abstract This community service was carried out at Siak Sri Inderapura, Siak Regency, Riau Province. The activity was done in the form of a lay seminar on metabolic syndrome hazards and how to prevent it which targeting the general public. This activity aims to educate the public about metabolic syndrome, its danger to health, and how to prevent it so that people are expected to be able to recognize the signs as early as possible. The service activity begins with filling out the pretest questionnaire, delivery of talks by a health expert and discussion between participants and speaker, then at the end of the event the participants return to fill in the posttest questionnaire. The results of this community service showed a significant increase in knowledge from participants of lay seminars "The dangers of metabolic syndrome and how to prevent it" in Siak Sri Inderapura, Siak Regency, Riau. Abstrak. Pengabdian masyarakat ini dilaksanakan di Kota Sri Inderapura, Kabupaten Siak, Provinsi Riau. Kegiatan ini berupa seminar awam dengan topik bahaya sindroma metabolik dan cara pencegahannya dengan sasaran masyarakat umum. Kegiatan ini bertujuan untuk mengedukasi masyarakat mengenai gejala sindroma metabolik, bahayanya terhadap kesehatan, dan cara pencegahannya sehingga diharapkan masyarakat dapat mengenali tanda-tandanya sedini mungkin. Kegiatan pengabdian diawali dengan pengisian kuisioner pretest, penyampaian materi oleh pakar kesehatan dan dilanjutkan proses tanya jawab antara peserta dan narasumber, selanjutnya pada akhir acara para peserta kembali diminta untuk mengisi kuisioner posttest. Hasil pengabdian masyarakat menunjukkan terdapat peningkatan pengetahuan yang signifikan dari peserta seminar awam “Bahaya sindroma metabolik dan cara pencegahannya” di Kota Siak Sri Inderapura, Kabupaten Siak, Riau.

Penapisan Tekanan Darah Tinggi Pada Masyarakat Kota Bangkinang Sebagai Upaya Pencegahan Penyakit Ginjal Kronis: Screening for High Blood Pressure in Bangkinang City Community As an Effort to Prevent Chronic Kidney Disease Fajri Marindra Siregar; Hendra Asputra; Nanda Fito Mela
Jurnal Pengabdian Kesehatan Komunitas Vol. 2 No. 1 (2022): Jurnal Pengabdian Kesehatan Komunitas
Publisher : STIKes Hang Tuah Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25311/jpkk.Vol2.Iss1.1215

Penyakit ginjal kronis (PGK) merupakan masalah kesehatan dunia yang insidensi dan prevalensinya semakin meningkat dengan keluaran yang buruk dan biaya perawatan yang tinggi. Salah satu faktor risiko penyebab PGK adalah tekanan darah tinggi. Kegiatan pengabdian masyarakat ini bertujuan untuk melakukan penapisan tekanan darah tinggi pada masyarakat sebagai upaya pencegahan PGK. Penapisan dilakukan dengan melakukan pemeriksaan tekanan darah dan edukasi pada peserta yang terdeteksi memiliki tekanan darah tinggi. Kegiatan pengabdian ini dilaksanakan di Kota Bangkinang, Kabupaten Kampar, Provinsi Riau. Dari 100 orang masyarakat yang mengikuti kegiatan didapatkan sebanyak 19% memiliki tekanan darah normal, 33% prehipertensi, 23% hipertensi derajat 1 dan 25% hipertensi derajat 2. Tingginya angka kejadian tekanan darah tinggi yang ditemukan pada kegiatan penapisan ini menggambarkan urgensinya usaha kesehatan berbasis masyarakat sebagai upaya tindak lanjut pencegahan penyakit ginjal kronis dan penyakit lainnya yang lebih serius. Abstract Chronic kidney disease (CKD) is a global health problem that incidence and prevalence increase with poor outcomes and high treatment costs. One of the risk factors for CKD is high blood pressure. This community service activity aims to screen the community for high blood pressure to prevent CKD. Screening is done by checking blood pressure and educating participants who are detected to have high blood pressure. This service activity is located in Bangkinang City, Kampar Regency, Riau Province. Of the 100 people who participated in the program, 19% had normal blood pressure, 33% had prehypertension, 23% had hypertension grade 1, and 25% had hypertension grade 2. The high incidence of high blood pressure in this screening activity illustrates the urgency of community-based health programs as a follow-up effort to prevent chronic kidney disease and other more severe diseases.

The persistence of covid-19 infection, a golden opportunity to be observed Fajri Marindra Siregar; Sarmoko
Acta Biochimica Indonesiana Vol. 3 No. 2 (2020): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.v3i2.62

Prediksi Hasil Ujian Kompetensi Mahasiswa Program Profesi Dokter (UKMPPD) dengan Pendekatan ANFIS Fajri Marindra Siregar; Gunadi Widi Nurcahyo; Sarjon Defit
Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Vol 2 No 2 (2018): Agustus 2018
Publisher : Ikatan Ahli Informatika Indonesia (IAII)

The main objective of this study was to predict the outcome of student's competency exam of the medical profession (UKMPPD) using Adaptive Neuro-Fuzzy Inference System (ANFIS). Data obtained from the Faculty of Medicine Universitas Riau’s student database in 2015 which amounted to 170 data. Input variables were membership status, length of study, and grade point average. Furthermore, the data were analyzed using MATLAB software by setting the number of membership function 2 2 2 and Gbell membership function. The results showed that the method is able to predict the outcome of UKMPPD with Mean Average Percentage Error (MAPE) 0.07%, minimum 0.00%, and maximum 0.44%.

Co-Authors afdhal cahya pratama Astrid Faradisty Chunin Widyaningsih Dedi Afandi Dedi Afandi Elita Rafni Fikri Ruriandy Aufi Gunadi Widi Nurcahyo Hendra Asputra Hendra Asputra Imelda Tresia Pardede Jefrizal Jefrizal Khodijah Khodijah Maysarah Elnas Mela, Nanda Fito Mukhyarjon Novi Silvia Hardiany Rahmat Azhari Kemal Revinta Mozache Hardiman Riki Sukiandra Rita Endriani Sarjon Defit Sarmoko Sarmoko Sri Widia Azraki Jusman Suyanto Suyanto Talitha Lailatul Hafizah Tutut Ismi Wahidar Zahtamal Zahtamal

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