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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Published by Universitas Gadjah Mada
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
Arjuna Subject : -
Articles 6 Documents
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Search results for , issue "Vol 10, No 3" : 6 Documents clear
Evaluasi Kualitas Hidup Pasien Kanker Serviks yang Mendapat Regimen Kemoterapi Cisplatin-Vinkristin-Bleomisin dan Carboplatin-Paklitaksel Suwendar Suwendar; Achmad Fudholi; Tri Murti Andayani; Herri S. Sastramihardja
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.44475

Abstract

Cervical cancer is one type of cancer with a high prevalence in women. Quality of life of someone with cervical cancer will decrease. Quality of life can also decrease because of chemotherapy regimens. The purpose of this study was to evaluate the impact of cisplatin-vincristine-bleomycin and carboplatin-paclitaxel regimens on the quality of life of patients. Through this research how the difference in quality of life of patients with cervical cancer before and after chemotherapy could be known. Additionally, the  differences impact on the quality of life of the two regimens also were observed.  The study was conducted by using cross sectional design in hospitalization patients. Data were taken prospectively by conducting field observations. Measuring the quality of life was done using the EORTC QLQ-C30 questionnaire. Differences of domain values before and after chemotherapy in each regimen were analyzed by paired t-test (p <0.05). Quality of life difference between two regimens were analyzed by unpaired t test (p<0.05). The results showed that there was an increasing trend of the value of the functional domain, impairment of symptoms domain and an increase in the value of global health status domain after three cycles of chemotherapy of two regimens, except the symptoms of nausea and vomiting and loss of appetite that showed an increasing trend. Patients who received cisplatin-vincristine-bleomycin regimen showed a significant increasing (p = 0.009) in decreased of appetite symptom’s scores. No significant differences in the quality of life of patients who delivered chemotherapy regimen of cisplatin-vincristine-bleomycin compared to carboplatin-paclitaxel regimen.
Evaluasi Perencanaan Persediaan Antibiotik Secara Kuantitatif Di Instalasi Farmasi Rumah Sakit Tipe A Venna Laurensia; Gusti Noorrizka Veronika Achmad; Raswita Diniya; Ivonne Soeliono
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.49035

Abstract

Planning an inventory of antibiotics that are not good will cause problems in planning, which are over-supply of antibiotics (stagnant) and lack of antibiotic stock (stockout). In this study an quantitative evaluation of antibiotic inventory planning was carried out using the Economic Order Quantity (EOQ) and Maximum-Minimum Stock Level (MMSL) control methods in 2017 at Type A Hospital’s Pharmacy Department. The EOQ method aims to minimize the number of orders while the MMSL method is used to determine the minimum and maximum stock of antibiotics that must be ordered. The results were compared with the need for 2018 then calculations are carried out to determine the amount of stagnant and stockout antibiotics. The number of antibiotics that were stagnant by EOQ method simulation was 44.73% and by MMSL method was 48.02%, while the number of antibiotics stocked by EOQ method was 38.15% and by MMSL method was 42.76%. The category of antibiotic supplies in 2018 in real terms which was included in a stagnant state was 23.68%, stockout ie 55.26% of 152 antibiotics. Evaluation of antibiotic inventory planning using the EOQ method results in the calculation of lower order quantities while the number of orders with MMSL is higher. To find out more broadly about the evaluation of inventory planning in the hospital needed further research by taking into account all drugs not just antibiotics.
Evaluasi Penggunaan Aspirin Jangka Panjang terhadap Fungsi Ginjal Pasien Penyakit Jantung Koroner Ema Pristi Yunita; Puji Astuti Nur Hidayanti; Cholid Tri Tjahjono
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.53312

Abstract

Low-dose aspirin (75-100 mg/day) is a long-term platelet antiaggregation therapy for certain coronary heart disease (CHD) patients. This study aims to evaluate the long-term use of aspirin on kidney function by examining the changes in the levels of serum creatinine, blood urea nitrogen (BUN), and creatinine clearance of CHD patients. The research method used was a prospective observational cohort analysis. The number of study subjects was 37 CHD patients who took 80 mg/day of aspirin and never experienced kidney disease. Serum creatinine and BUN levels were examined in the 1st and 3rd month of the study. Patient creatinine clearance values were calculated using the Cockcroft-Gault equation. The results of the study showed that the mean levels of serum creatinine, BUN, and creatinine clearance on the 1st and 3rd month were 1.03 ± 0.27 mg/dL and 1.03 ± 0.29 mg/dL; 13.05 ± 4.10 mg/dL and 14.65 ± 4.44 mg/dL; 73.16 ± 18.14 mL/min and 72.92 ± 19.76 mL/min, respectively. The paired t-test results showed that the differences in the mean of creatinine serum, BUN, and creatinine clearance on the 1st and 3rd month were not statistically significant (p > 0.05). The One Way ANOVA test results on the effect of the duration of aspirin use on kidney function were also not statistically significant (p > 0.05) however there is a tendency to decrease creatinine clearance and increase in serum creatinine and BUN. Long-term use of low-dose aspirin has the potential to cause a decrease in kidney function that is seen from a decrease in creatinine clearance as well as an increase in serum creatinine and BUN.
The Effectiveness of Zoledronic Acid and Ibandronic Acid in Delaying Skeletal-Related Events in Multiple Myeloma in Indonesia Nutrisia Aquariushinta Sayuti; Tri Murti Andayani; Dwi Endarti; Kartika Widayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.55943

Abstract

Zoledronic acid and ibandronic acid are listed in the Indonesian national formulary to prevent skeletal-related events (SRE) in patients diagnosed with bone metastasis in multiple myeloma (MM), with limited evidence to compare their effectiveness. This study aimed to investigate the effectiveness and safety of zoledronic acid and ibandronic acid in delaying SRE. The method was the retrospective, with data obtained from the multicenter study for MM patients with bone metastasis (aged over 18 years), based on medical records between January 2016 and December 2018. Patients were assigned to zoledronic acid and ibandronic acid groups. The clinical outcome was the next SRE which consists of vertebral/bone fracture, spinal cord compression leading to the need for surgery or radiation, and adverse event (AE) due to 2 years of drugs usage. Result of this research was made up of a total of seventy (70) patients with  40  in the zoledronic acid group, and 30 in ibandronic acid. At median treatment duration of 8 months (range: 2 – 24 month), SRE incident in zoledronic acid and ibandronic acid were 20.0 % and 23.3 % respectively. Furthermore, their mean SRE free survival times were 21 months [95% confidence interval (CI) 19 - 23 months], and 19 months [95% CI, 16 – 22 months], respectively. Also, their time intervals were not significantly different (p>0.05). The osteonecrosis of the jaw (ONJ) was AE which occurred more in zoledronic acid than ibandronic acid. The conclusion was zoledronic acid tends to delay SRE time compared to ibandronic acid, although more ONJ occur.
The Effect of Based Services Medication Therapy Management on Treatment Adherence and Quality of Life of Diabetes Mellitus Patients Rachma Malina; Nanang Munif Yasin; Chairun Wiedyaningsih
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.58052

Abstract

Diabetes mellitus is a chronic metabolic disorder that is characterized by hyperglycemia. Diabetes mellitus need appropriate therapeutic management, because it can cause complications. On of the services that can do to improve diabetes control is Medication Therapy Management (MTM). MTM is a new service that will help pharmacist to improve patient adherence and quality of life. This study aims to determine the effect of based services MTM on treatment adherence and quality of life in patients with diabetes mellitus. This study was an experimental study using a quasi-experimental with one group pretest and posttest design which was conducted in Tegalrejo, Jetis and Gedontengen Health Center Yogyakarta City. Variables measured were medication adherence using the Morisky-Green Levine Medication Adherence Scale (MGLS) questionnaire and quality of life using Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) before and after MTM services. The effect of MTM on medication adherence was analyzed using Wilcoxon test and the effect of MTM on quality of life using Paired T-Test. The patients participate in this study were 20 people, with average score of adherences before application of MTM was 2.20±0.410 to 1.80±0.616 after the application of MTM (P=0.005) and the average of the patient's quality of life was 73.82±7.918, increased to 76.42±5,623 after MTM service (P=0.033). Statistically mean, there is a difference in adherence and quality of life before and after MTM services. Therefore, it can be concluded that MTM-based services performed by pharmacists have a significant effect on improving medication adherence and quality of life for DM patients. Moreover, it can facilitate monitoring patient therapy, and identification of problems related to the treatment.
The Usage of Dosing GAMA Application to Evaluate the Appropriateness of Drug Doses in Hospitalized Patients with Renal Impairment Vidiya Gunarsih; Fita Rahmawati; Djoko Wahyono
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.58534

Abstract

An application named ‘Dosing GAMA’ has developed for drug doses adjustment in patients with renal and hepar impairment. Dosing GAMA is targeted for clinical Pharmacists to calculate and make dose recommendations for patients, based on renal and hepatic conditions. This study aims to identify the appropriateness of drug dosage adjustment by using Dosing GAMA application in hospitalized patients with renal impairment and to determine the risk factors for the drug dose inappropriateness. This study was a retrospective observational descriptive study, cross-sectional design, used a consecutive sampling technique. The source of the data was Medical Record of hospitalized patients with renal impairment (creatinine clearance ≤50 mL/min) from 2018 of February till 2020 of March in the Academic Hospital of UGM. The names and the doses of the drugs were filled to Dosing GAMA application, and it would evaluate the appropriateness of drug doses. There were 570 drugs of 73 medical records included in this study. This study revealed Dosing GAMA could assess 144 drugs (25,6%) need to adjust, and 82 drugs (56,9%) were inappropriate doses. There were significant correlations of the age characteristic (p=0,000) and the creatinine clearance value (p=0,012) to the drugs dose appropriateness. There were inappropriate doses need to adjust in the hospital. So, the use of health-based technology expected for pharmacists to improve the use of drugs rationally.

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