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JFL : Jurnal Farmasi Lampung
Published by Universitas Tulang Bawang
ISSN : 23552506     EISSN : 25984896     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health
The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its application.
Arjuna Subject : -
Articles 80 Documents
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ANALISIS KADAR NITRIT PADA SOSIS SAPI KEMASAN YANG BEREDAR DI PASAR TRADISIONAL KOTA BANDAR LAMPUNG SECARA SPEKTROFOTOMETRI UV-VIS Samsuar Samsuar; Akhmad Rokiban; Dodo Hardoyo
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.331

Abstract

Abstract The use of nitrite as a preservative and provider of the stable red color, aroma as well as taste for the meat is allowed within processed meat products, such as beef sausage. However, it should be noted that its use does not exceed the maximum permitted limit so as not to negatively impact human health. Excess nitrite in the human body can cause acute poisoning, namely methemoglobinemia and chronic poisoning as a result of the formation of carcinogenic nitrosamine derivatives. This research aims to determine whether the levels of nitrite contained in the packaged beef sausage distributed in the traditional market of Bandar Lampung is in accordance with the regulations of The Indonesia Food and Drug Authority or Indonesia FDA No. 36 of 2013 which is not more than 30 mg/kg. The analysis of nitrite levels in the sample was carried out using with UV-Vis Spectrophotometry method based on diazotation reaction between nitric acid and sulfanilamide forming diazonium salts. The products were then reacted again with naphthyl ethylenediamine to form a purplish red compound whose absorbance was measured at a wavelength 0f 543,8 nm. From the results of the analytical methods validation, it was obtained that the value of the correlation coefficient was 0,9997, the coefficient of determination 0,9994, the coefficient of variation 1,2121%, the range of percent recovery between 98,630-101,240%, and the detection and the quantitation limit respectively at 0,0187 ppm and 0,0623 ppm. This indicates that all test parameters meet the requirements for their use. The result of determining the average levels of nitrite in the samples show that there were two samples that had levels exceeding the maximum allowed limit, i.e sampel C=40,407 mg/kg and sample D=33,181mg/kg while sample A=18,963 mg/kg, sample B=9,427 mg/kg, sample E=9,423 mg/kg and sample F=8,689 mg/kg did not exceed the maximum allowed limit. Keywords: Beef Sausage, Nitrite, UV-Vis Spectrophotometry, Method AnalysisValidation
EVALUASI PENGGUNAAN OBAT PADA PENDERITA DIARE AKUT PASIEN PEDIATRI DI INSTALASI RAWAT INAP RUMAH SAKIT ADVENT BANDAR LAMPUNG PERIODE JULI – DESEMBER 2019 Subur Widodo; Novita Tri Wahyuni; Lea Yekti Utami
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.333

Abstract

Abstract Acute diarrhea is diarrhea that lasts less than 14 days. Regarding its severity, acute diarrhea is classified as mild, moderate or severe. Mild when signs of dehydration are not observed, moderate when there are mild or moderate signs of dehydration and rehydration can be done orally and severely when it results in more intense dehydration with or without electrolyte disturbances, and requires intravenous therapy. Diarrhea disease in the Inpatient Installation Bandar Lampung Adventist Hospital is the 10 biggest diseases and has never been evaluated on the use of drugs in pediatric patients. This study aims to evaluate the use of drugs in patients with acute diarrhea inpatients installation at the Bandar Lampung Adventist Hospital calculated from July to December 2019 data. This research is a descriptive study with retrospective data collection. The data collection process begins by tracing medical records of acute diarrhea patients. The population of acute diarrhea cases was 152 patients and then the number of samples obtained was then selected according to the inclusion criteria as a sample of 60 patients. From the research results it is known that the use of drugs in patients with acute diarrhea in pediatric patients includes antibiotics, electrolyte solutions, analgesic/antipyretics, antidiarrheals and other drugs (antihistamines, supplements and probiotics). The validation of drug use on the right indicators, the right patient and the right dose has reached 100%, the right indicator is 37% and the drug is 63% incorrect, this is due to the use of antibiotics without laboratory results that show acute diarrhea due to infection. Keywords: acute diarrhea, evaluation of drug use, pediatric
EVALUASI RASIONALITAS PENGGUNAAN OBAT DIABETES MELITUS TIPE II PADA PASIEN RAWAT JALAN DI PUSKESMAS PASIR SAKTI TAHUN 2019 Dwi Aulia Ramdini; Lilik Koernia Wahidah; Dwi Atika
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.334

Abstract

Abstract Diabetes mellitus is a metabolic disease characterized by hyperglycemia, due to abnormal insulin secretion, insulin action or both. Hyperglycemia is a condition in which blood glucose levels increase or exceed normal limits. This study aims to evaluate the treatment of type II diabetes mellitus in outpatients in Puskesmas Pasir Sakti. This research is a nonexperimental research with a descriptive design taken retrospectively. The sample in this study were all outpatients with a diagnosis of type II diabetes mellitus at Puskesmas Pasir Sakti 2019. The sampling technique used was Total sampling. The sample of this study is the medical record data of patients with type II diabetes mellitus in 2019 adjusted for inclusion criteria. Characteristics based on gender of patients with type II diabetes melitus there are 23 male patients that is 29% and 57 female patients that is 71 %. Characteristics based on the age of most patients in the Elderly (46-65 years) as many as 65 patients (81%). cases of type II diabetes mellitus patients without complications were 39 patients (49%) cases of type II diabetes mellitus patients with complications of 41 patients (51%). The results of the rationality of antidiabetic use in outpatients at the Puskesmas Pasir Sakti in 2019 According to PERKENI 2015 obtained the use of drugs based on the exact parameters indicated as much as 97.5%, the right drugs as much as 98.75%, the right dosage as much as 100%, the right way of administration as much as 100%, the exact time interval of 100%, and medication adherence of 100%. Treatment of type II diabetes melitus who received rational therapy was 96,25% while irational therapy is 3,75%. Keywords: Diabetes Mellitus, Evaluation, Medicine, Rationality.
PENGARUH KRONOFARMAKOLOGI TERHADAP KADAR KOLESTEROL TOTAL DAN TRIGLISERIDA DALAM DARAH PASIEN PENGGUNA OBAT GOLONGAN STATIN DAN FIBRAT Resna Sari Asih; Ilham Alifiar; Yedy Purwandy
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.335

Abstract

ABSTRACT Chronopharmacology is a therapy based on circadian rhythms that can be said to be relevant if the risk and symptoms of the disease are predicted to vary over time. This study aims to determine the effect of chronopharmacology on total cholesterol and triglyceride levels in the blood of patients with fibrates and statin groups, so that patients with certain diseases are encouraged to take drugs according to the organ picket hours or circadian rhythms. This study was an observational descriptive study with a cross sectional study design involving 18 patients. Primary data were obtained through interviews and checking total cholesterol and triglyceride levels while secondary data were obtained from the patient's medical record. Based on the results of the analysis using SPSS for statin drug use in the morning and at night getting a value of P = 0.003. whereas for drug use in the fibrat group in the morning and evening, P = 0.083 was obtained. Based on the results of the research that has been done, it can be concluded from 18 patients using statins and fibrates in RSUD Dr. Soekardjo Tasikmlaya, for the use of statin drugs at night is more beneficial, but in the use of fibrates in the morning or evening the same effectiveness. Keyword : chronopharmacology, statin, fibrat
EVALUASI PENGGUNAAN OBAT PADA PASIEN HIPERTENSI RAWAT JALAN DI RUMAH SAKIT UMUM WISMA RINI PRINGSEWU TAHUN 2019 Ramadhan Triyadi; Akhmad Rokiban; Anggun Carima
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.336

Abstract

Abstract Hypertension is a non-communicable disease characterized by the increase of systolic blood pressure is >140 mmHg and diastolic blood pressure is >90 mmHg. Hypertension is also the major risk factor of other cardiovascular disease. The incidence rate of hypertension with or without complications increases every year, so the potential for inaccurate use of drugs is increasing. The purpose of this research is to determine the characteristics of hypertension outpatients and the proper hypertension drug use in hypertension outpatients at Wisma Rini General Hospital Pringsewu in 2019 based on the proper patient, the proper indication, the proper drug, and the proper dose using the standard reference of Guidelines JNC VIII. This research is descriptive research, the data was collected retrospectively based on medical records. The sample collection technique in this research is using a purposive sampling technique. The results in this study obtained from 110 patient samples diagnosed with the hypertension showed that most of hypertension patients are women (55,46%), mostly aged 56-65 years old (40%), and the most taken hypertension drug is CCB group amlodipine with 78 patients (71%). The evaluation of antihypertensive drug use obtained is proper patient with 110 patients (100%), proper indication with 110 patients (100%), proper drug with 92 patients (75,6%), and proper dose with 110 patients (100%). Keywords: Antihypertensive, Hypertension, Accuracy drug use.
PENGARUH METODE PERMAINAN BOARDGAME EDUCATION “PHARMAPOLEIN” TERHADAP PEMAHAMAN MATERI KEFARMASIAN MAHASISWA Ilham Alifiar; Vidya Febrasca Tenderly; Annisa Nurhayati
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.337

Abstract

ABSTRACT Mission of pharmacy education is to develop and nurture skills in lifelong learning. Broad insight, skills in communication, and teamwork is a must for the pharmaceutical profession. The learning method greatly affects the results of understanding each individual, especially in understanding pharmaceutical material which is considered difficult. Educational games are used as a teaching method because they help complement and strengthen the material being taught. Board games have continued to grow in popularity and the pedagogical value of the games has been supported many times. So, this board game is designed to have enough challenging elements to nurture student interest. The game tactic used collaboration and competition in the classroom. Competition has been found to increase motivation. Thus, that motivation can be used to understand the pharmaceutical material contained in the game. Aim this study is to determine the potential modification of the monopoly board game in increasing student comprehension of pharmaceutical material. The pharmapolein game was examined on both pharmacy and non-pharmacy student respondents (n = 12). From the test, it was obtained a correlation value of and 0.885 and a significance value of 0.000, so the conclusion was that the board game game could increase student knowledge in mastery of pharmaceutical science. Keywords: Board Games, Pharmapolein, Pharmacy
EVALUASI PENGGUNAAN ANTIBIOTIK PNEUMONIA DENGAN METODE ATC/DDD PADA PASIEN PEDIATRI DI INSTALASI RAWAT INAP RSUD. DR. A. DADI TJOKRODIPO BANDAR LAMPUNG TAHUN 2019 Lilik Koernia Wahidah; Novita Tri Wahyuni; Deska Maharani Putri
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.338

Abstract

ABSTRACT Pneumonia is an inflammation of the lungs that causes pain during breathing and limited oxygen intake. Antibiotics are the main therapy for pneumonia, appropriate and rational antibiotic therapy will determine the success of treatment to avoid bacterial resistance. The purpose of this study was to evaluate the use of pneumonia antibiotics in pediatric patients with the ATC / DDD method in pediatric patients in the Hospital Dr. Hospital. A. Dadi Tjokrodipo Bandar Lampung in 2019. This research is descriptive in nature with retrospective data collection. The sampling technique used was purposive sampling with a sample size of 70 patients with pediatric pneumonia. The data obtained were analyzed by using ATC / DDD and DU 90% methods. The results showed that from 70 samples studied, it was found that the patient characteristics were based on gender, namely 61.42% of them were male and based on age, namely 65.71% were infant patients aged 1 month - 2 years. The total use of antibiotics was 65.92 DDD / 100 days of hospitalization and antibiotics that entered the 90% DU segment, namely ampicillin (27.53 DDD / 100 days of hospitalization), gentamicin (8.39 DDD / 100 days of hospitalization), azithromycin (7 , 13 DDD / 100 days of care), amoxicillin (6.88 DDD / 100 days of hospitalization) and ampicillin sulbactam (6.6 DDD / 100 days of hospitalization). Then evaluated the use of antibiotics and the results were 100% correct, 100% correct indication, 57.4% correct dose and 100% correct time interval of administration. The use of antibiotic pneumonia in Dr. A. Dadi Tjokrodipo still needs to be improved again, especially regarding the administration of antibiotic doses. Keywords: Antibiotics, ATC, DDD, Pediatrics, Pneumonia.
ANALISIS WAKTU TUNGGU PELAYANAN RESEP PADA PASIEN RAWAT JALAN DI RSUD DR. H. ABDUL MOELOEK PROVINSI LAMPUNG Subur Widodo; Masyuri Yusuf; M. Desirwan Dinata
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.339

Abstract

Abstract Pharmaceutical services are health services in hospitals that are expected to meet minimum service standards (SPM) in an effort to improve the quality of services to patients. One of the pharmaceutical service categories in the minimum service standard (SPM) in hospitals is the waiting time for prescription services in the form of nonconcoction drugs is the grace period from the time the patient submits a prescription to receiving non-concoction drugs with a minimum standard set by the Ministry of Health that is ≤ 30 minutes, whereas the waiting time for prescription concoction services is the grace period from the time the patient submits the prescription until receiving the concoction drug that is ≤ 60 minutes. This research was conducted to analyze the waiting time for outpatient prescription services in Dr. H. Abdul Moeloek based on hospital minimum service standards (SPM) as an overview of prescription services, evaluation materials and pilots in an effort to improve the quality of pharmaceutical services. This research will be conducted at the pharmacy outpatients Dr. H. Abdul Moeloek in August - September 2019 with a sample of 172 recipes, consisting of 98 non-concoction recipes and 74 recipe concoctions. Based on the research that has been done, the results of waiting time for non-concoction prescription services in the Outpatient Installation of Dr. H. Abdul Moeloek is in accordance with the SPM at the Hospital with an average waiting time of 11 minutes. Waiting time for prescription concoction services in Dr. Outpatient Hospital Installation H. Abdul Moeloek is in accordance with the SPM at the Hospital with an average waiting time of 19.4 minutes. Keywords: Pharmaceutical services, waiting time, pharmaceutical service standards.
PENGARUH TINGKAT PENGETAHUAN OBAT DAN PENYAKIT HIPERTENSI TERHADAP KEPATUHAN PENGAMBILAN OBAT PENDERITA HIPERTENSI DI PUSKESMAS ROWOREJO KABUPATEN PESAWARAN LAMPUNG Dwi Efayanti; Subur Widodo; Ade Kristanto
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.340

Abstract

ABSTRACT Hypertension is a disease that contributes to death by 29.8%, factors that cause an increase in the prevalence of hypertension include patient compliance, compliance itself is influenced by one's behavior factors, one of which is knowledge. This study aims to look at the effect of the level of knowledge on the compliance of taking drugs with hypertension in Roworejo Public Health Center, Pesawaran Regency, Lampung. This research is a descriptive analysis research, conducted by giving a questionnaire that has been tested for validity and reliability and has obtained ethical permission from the ethics committee of Malahayati University, Bandar Lampung with No.485 / EC / Kep-UNMAL / VII / 2019. The level of compliance with drug taking can be seen from the recap of prescriptions for hypertension in April-June 2019. The category of adherence level uses the formula MPR (Medication Possession Ratio) which is <80% categorized as non-compliant and> 80% categorized as compliant. The data is then analyzed using linear regression, if the significant value <0.05 means that there is an influence between the variable X on the Y variable, if the significant value> 0.05 means that there is no influence between the variable X on the Y variable. The results showed that the most hypertensive patients aged> 60 years 81%, female sex 59%. The level of knowledge of the respondents mostly had medium knowledge 98% and high knowledge 2%. The level of compliance with respondent's drug taking was only 3% of respondents who were compliant and 97% of respondents were not compliant From the results of linear regression analysis in this study showed that the value of Significant value 0.000> 0.05, which can be concluded that there is an influence between the variable level of knowledge of the level of compliance with drug taking. Keywords: Hypertension, Compliance with drug uptake, Knowledge, MPR, Roworejo.
ANALISA TINGKAT PENGETAHUAN DAN PERILAKU TERHADAP PENGGUNAAN OBAT INFLUENZA DAN BATUK SECARA SWAMEDIKASI DI DESA MUARA BURNAI I KABUPATEN OGAN KOMERING ILIR Mashuri Yusuf; Subur Widodo; Aqbar Raka Irwansyah
JFL : Jurnal Farmasi Lampung Vol. 9 No. 2 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i2.341

Abstract

Abtract Many Indonesian people do self-medication as an attempt to treat complaints / pain they experience, the benefit of self-medication is safe when used according to the rules, effective for eliminating complaints, cost efficiency, can play a role in making therapeutic decisions, self-medication is usually done to overcome complaints and minor illnesses that are often experienced by people, such as fever, pain, dizziness, cough, influenza, ulcers, intestinal worms, diarrhea, skin diseases and others. This study aims to determine the level of knowledge and behavior towards the use of influenza drugs and cough by self-medication in Muara Burnai I Village, Ogan Komering Ilir district. The research analyzed was descriptive observational. The sampling technique uses the accindental sampling method. The instrument used in this study was a questionnaire. The results of the analysis of the level of knowledge and behavior analysis showed that there was a relationship between the level of knowledge and the behavior of influenza drug use and cough by self-medication was analyzed using the Chi-Square test sample of 100 respondents. The results of this study indicate that 36% have high knowledge and 64% have low knowledge in self-influencing and cough swamedication while 43% have high behavior and 57% have low behavior in influenza and cough swamedication in Muara Burnai I Village, Ogan Komering Ilir District. Based on the Chi-Square test results showed that the value of p = 0,000 (0.05). Shows that there is a relationship between the level of knowledge and swamedication behavior in Muara Burnai I Village, Ogan Komering Ilir district. Keywords : Influenza and cough, drug use behavior, swamedication, knowledge level.

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