cover
Contact Name
Laila Susanti
Contact Email
laila.susanti@utb.ac.id
Phone
-
Journal Mail Official
laila.susanti@utb.ac.id
Editorial Address
-
Location
Kota bandar lampung,
Lampung
INDONESIA
JFL : Jurnal Farmasi Lampung
ISSN : 23552506     EISSN : 25984896     DOI : -
Core Subject : Health, Science,
The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its application.
Arjuna Subject : -
Articles 80 Documents
KOMBINASI EKSTRAK DAUN BIDARADENGAN DAUN KEMANGI SEBAGAI ANTIBAKTERI TERHADAP Staphylococcus aureus DAN Escherichia coli. Muhammad Richja As seffi; Yuli Wahyu Tri Mulyani; Annisa Mulia Anasis
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.807

Abstract

Infectious diseases are still at the top of the list of causes of illness and death in developing countries including Indonesia, Staphylococcus aureus and Escherichia coli are commonly found around the human environment, therefore prevention is needed to reduce infection by utilizing plants that have antibacterial effects such as bidara leaves with basil leaves. This study aims to determine the antibacterial activity of the combination of bidara leaf extract and basil leaves, and to determine the best combination concentration in inhibiting the growth of Staphylococcus aureus and Escherichia coli bacteria compared to single extracts and positive controls. Using the diffusion method, the combination of dau bidara extract with basil leaves is K1 (0% + 100 %), K2 (20 + 80%), K3 (40% + 60%), K4 (50% + 50%), K5 (60 %+40%), K6 (80% + 20%), K7 (100% + 0%), K(-) Aquadest and K(+) Ampicillin. In the bacterial test (well diffusion method). The variable measured in this study was the diameter of the inhibition zone formed by the combination of extracts. Data analysis was tested using One Way Anova. The sig value for Staphylococcus aureus was 0.000≤0.05, while for Escherichia coli was 0.000≤0.05, it indicated that there was a significant difference between the test groups. The results of this study obtained the largest inhibition zone on bacteria, S. aureus, namely at K7 14.46 mm had a strong inhibitory response, while in bacteria E. Coli was found in K7 with the largest average value of 17.95 mm having a strong inhibitory response. This study can be concluded that the combination of bidara leaves and basil leaves has greater antibacterial power against Staphylococcus aureus and Escherichia coli bacteria than single extracts and positive control. Keywords: Ampicillin, antibacterial, Bidara leaves, basil leaves, diffuse
STUDI FARMAKOVIGILAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI RAWAT JALAN DI DR. A. DADI TJOKRODIPO BANDAR LAMPUNG PERIODE OKTOBER–NOVEMBER 2021 Lilik Koernia Wahidah; Novita Tri Wahyuni; Dion Yongtama
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.814

Abstract

Hypertension, also known as high blood pressure, is systolic pressure140 and diastolic pressure 80 mmHg. The more blood pressure is pumped by the heart and the narrower the arteries, the higher the blood pressure. This study aims to determine the occurrence of adverse drug reactions in hypertensive patients in RSD DR. A. Dadi Tjokrodipo Bandar Lampung. This research is a descriptive research with total sampling method. Collecting data by looking at the patient's medical record data. The results showed that the female sex was more dominant in suffering from hypertension, namely 20 female patients (62.5%) and 12 male patients (37.5%). The highest age characteristics were found in the age range of 46-55 years as many as 14 patients (43.75%). The most characteristic of hypertension was in the case of stage 2 hypertension with a total of 17 patients (53.12%). The highest pattern of drug use was amlodipine (37.5%). The incidence of drug interactions was 10 cases (31.25%) with minor severity. The highest incidence of ADR was in the "moderately probable" 1-4 with a total of 15 cases (46.87%). Keywords: ADR, hypertension, drug interactions, antihypertensive drugs
PENGARUH PERAN FARMASIS TERHADAP PENGETAHUAN PASIEN TENTANG PENATALAKSANAAN PENYAKIT DIARE DI PUSKESMAS RAWAT INAP SUKARAJA KOTA BANDAR LAMPUNG Nopiyansyah Nopiyansyah; Yuli Wahyu Tri Mulyani; Tanzilla Evitasari; Riko Herdiansah
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.820

Abstract

Diarrheal disease in developing countries like Indonesia is still a public health problem that can cause child death in the world. Diarrhea is a condition characterized by a person having loose stools three or more times a day. This case of diarrhea needs the role of pharmacists such as education to increase patient knowledge about the management of diarrheal diseases. Education is an activity to increase individual health knowledge regarding the management of risk factors for disease and healthy living behavior in an effort to improve public health status, prevent recurrence of disease and recover from disease. Factors that influence a knowledge that is age, education, occupation and sources of information. This study aims to determine whether there is a relationship between education and the level of patient knowledge about the management of diarrheal diseases at the Sukaraja Inpatient Health Center, Bandar Lampung City. This research is a non-experimental research with an observational analytic research design, using a one group pre-test and post-test study design that can be analyzed using the Statistical Product and Service Solutions (SPSS) method. This study was conducted for 2 months with the results of the study showing the characteristics of patients based on age, the most were 26-45 years old with 19 people (47.5%), high school education as many as 20 people (50%), and the most type of work was housewives 17 people (42.5%). The level of patient knowledge after being given an education can be seen from the Wilcoxon test with a significant value <0.005, stating that there is a relationship between education and the level of patient knowledge about the management of diarrheal diseases at the Sukaraja Inpatient Health Center, Bandar Lampung. Keywords: Diarrhea, Education, Knowledge Level.
UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN ANTING-ANTING (Acalypha australis L.) PADA MENCIT YANG DI INDUKSI KARAGENIN 1% Novita Sari; Samsuar Samsuar; Cindi Liyana
JFL : Jurnal Farmasi Lampung Vol. 11 No. 2 (2022): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v11i2.825

Abstract

Inflammation is the body's defense mechanism in response to tissue injury and disturbance by external factors. Anting-anting leaf (Acalypha australis L.) contain flavonoids and tannins suspected to have antiinflammatory activity.This study aims to examine the antiinflammatory activity of Anting-anting leaf (Acalypha australis L.) ethanol extract in mice induced by carrageenin 1%. Anti-inflammatory activity test was carried out using twenty-five (25) mice and each mice was induced using 1% carrageenin subplantarly. The mice were divided into 5 groups, group I as the negative control was administered 1% Na-CMC suspension, group II as the positive control was administered mefenamic acid 65 mg/kg BW, groups III, IV and V as the treatment group were administered 83, 166 and 332 mg/kg BW of Anting-anting leaf (Acalypha australis L.) ethanol extract. Inflammation volume was measured using a caliper every 60 minutes for 6 hours. Data were analyzed statistically using ANOVA (Analysis of variance). The results showed the Anting-anting leaf (Acalypha australis L.) ethanol extract 83, 166 and 332 mg/kg BW had anti-inflammatory activity, respectively (47.39 ± 1.7), (59.53 ± 0.9) and (50.56 ± 0.3)% in mice induced by carrageenin 1%. The ANOVA test showed there was a significant difference to the negative control. Based on the results of the study, it can be concluded that the ethanol extract from Anting-anting leaf (Acalypha australis L.) ethanol extract has anti-inflammatory activity with an effective dose of 332.28 mg/kg BW. Keywords: Anti-inflammatory, Anting-anting leaf, Acalypha australis L., carrageenin
PENETAPAN NILAI SPF (SUN PROTECTION FACTOR) SEDIAAN KRIM TABIR SURYA DI KOTA BANDAR LAMPUNG DENGAN METODE SPEKTROFOTOMETRI UV-VIS Subur Widodo; Akhmad Rokiban; Lilik Koernia Wahidah; Ikhrami Nurjannah
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.978

Abstract

Nowadays people awareness of the healthy skin importance is increasing, this is evident by the increasing cosmetic brands and there are many beauty clinics. Cosmetic products marketed should have the same efficacy as those listed on the packaging. Therefore, determining the efficacy of sunscreen preparations is very important to see the compliance of cosmetics manufacturers. The purpose of this study was to determine the suitability of the SPF product efficacy. The samples are the products which have SPF 30, the sample was tested by in vitro method using UV-Vis spectrophotometer, every 5 nm with the wavelength range 290 nm - 320 nm absorbance was measured, then analyzed with the mansur equation. Also did antioxidant activity tested with vitamin C as a control positive using the DPPH method. The principle of the DPPH method is the measurement of absorbance of DPPH radicals which are degraded due to the presence of antioxidant compounds using a UV-Vis spectrophotometer. The decrease in DPPH absorbance intensity is proportional to the increase in the concentration of antioxidant compounds expressed in IC50 (Inhibition Concentration 50). Sample 4 has an SPF value close to the value written on the packaging. Samples 2, 5, 1, 3, 6, 7 and 8 have SPF values ​​smaller than those listed on the packaging. The antioxidant activity obtained is rateable to the SPF value, sample 4 has the highest antioxidant activity followed by sample 2, sample 5, sample 1, sample 3, sample 6, and sample 7 and sample 8 have the lowest antioxidant activity. Keywords: Antioxidant , DPPH, UV-Vis spectrophotometry, SPF, Sunscreen
HUBUNGAN PENGETAHUAN DAN PERILAKU IBU DENGAN KEJADIAN ISPA PADA BALITA DI PUSKESMAS KALIREJO KECAMATAN NEGERI KATON KABUPATEN PESAWARAN Akhmad Rokiban; Novita Tri Wahyuni; Anita Purnama Sari
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.980

Abstract

Acute Respiratory Infection (ARI) is an upper or lower respiratory tract disease, where an acute infection process that lasts for 14 days, is caused by microorganisms that attack one or more parts of the respiratory tract, from the nose to the alveoli. This study aims to determine the relationship between knowledge and behavior of mothers with the incidence of ARI in children under five at the Kalirejo Public Health Center Negeri Katon District Pesawaran Regency. This type of research is descriptive observational. This research was conducted in June. The sample in this study was 100 respondents, the sampling technique in this study was accidental sampling, in this study the validity and reliabilitas Based on the chi-square results between knowledge and maternal behavior, a value (p value = 0.020) was obtained, maternal knowledge with the incidence of ARI was obtained (p value = 0.000), maternal behavior with ARI incidence was obtained (p value = 0.041). From this study, it can be concluded that the significance value < 0.05 indicates that there is a relationship between knowledge and maternal behavior, knowledge relationship with the incidence of ARI, and behavior with the incidence of ARI. Keywords: Incidence of ARI, Knowledge, Behavior
FRAKSI ETANOL RIMPANG KENCUR (Kaempferia Galanga L.) SEBAGAI ANTIBAKTERI TERHADAP Bacillus Subtilis dan Escherichia coli Yuli Wahyu Tri Mulyani; Annisa Mulia Anasis; Ari Yanto
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.995

Abstract

Abstract People were accustomed to use natural ingredients as traditional medicine because it was more economical and has little bit side effects compared with synthetic drugs. One of the herbs that has been widely known in the community as traditional medicine was the kencur rhizome. The kencur rhizome contains flavonoid and saponins which were antibacterial. The purpose of this study was to prove that there was the inhibition in ethanol fraction of kencur rhizome towards the growth of bacillus subtilis and Escherichia coli. The extraction process of kencur rhizome was carried out by maceration method used 70% ethanol solvent and continued with fractionation by using ethanol, n-hexane and chloroform solvents. Then, antibacterial test used diffusion method with concentrations of 25%, 50%, 75%, 100%, positive control of ciprofloxacin and negative control of aquadest. The test was continued by looking at the formation of inhibition zones around the diffusion and measured by using a calipers. The highest diameter of inhibition zone antibacterial activity of kencur rhizome at concentration 100% with a diameter of 22.00 mm in E. Coli and 20.00 mm for B. Subtilis, whereas positive control diameter inhibition zone of ciproflocaxin was 40.00 mm in E. Coli and 40.0 in B. Subtilis. The conclusion of this study was the ethanol fraction of kencur rhizome 100% concentration is the best concentration in the inhibition zone. Keywords: Antibacterial, Bacillus Subtilis, Escherichia coli, Kencur.
AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN KEMANGI (Ocymum x africanum L.) DENGAN DAUN PEPAYA (Carica papaya L.) TERHADAP Staphylococcus aureus Samsuar Samsuar; Yuli Wahyu Tri Mulyani; Ayu Mirda Sari
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.996

Abstract

Abstract Infectious diseases are one of the diseases that have suffered by many Indonesian people for a long time. S. aureus bacteria is the cause of pyogenic infections. Basil plants (Ocymum x africanum L.) and papaya plants (Carica papaya L.) can be used as antibacterial. This study aims to determine the antibacterial activity of the combination of basil and papaya leaf extracts against S. aureus bacteria. Using the Experimental Method with a combination of extract concentrations, namely K1 (0+100%), K2 (20%+80%), K3 (40%+60%), K4 (50%+50%), K5 (60%+40% ), K6 (80%+20%), K7 (100%+0%), K(-) aquadest, K(+) Oxfloxacin, followed by a test for S. aureus bacteria using the well method. The test results were analyzed using One Way Annova. with sig value (0.000) < p-value (0.05) followed by Tukey's further test which showed the combination of concentrations showed significant differences between the test groups. From this explanation, it can be concluded that the combination of basil leaf extract and papaya leaf extract can increase the inhibition zone, the largest inhibition zone is in K4 (50% basil leaf extract + 50% papaya leaf extract) the inhibitory response that appears 19.69 mm belongs to the strong category. inhibit the growth of S. aureus bacteria. Keywords: Antibacterial, basil leaf, papaya leaf, Staphylococcus aureus.
EVALUASI PENGGUNAAN OBAT HIPERTENSI PADA PASIEN RAWAT JALAN DI RUMAH SAKIT BHAYANGKARA POLDA LAMPUNG TAHUN 2020 Lilik Koernia Wahida; Novita Tri Wahyuni; Niluh Suastini
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.999

Abstract

ABSTRACT Hypertension is a condition in which a person experiences an increase in blood pressure above normal, which is higher than 140 mmHg systolic or 90 mmHg diastolic. Hypertension plays a very important role in causing the death of thousands of people, due to its dangerous side-effects, such as stroke, heart attack, heart failure, and kidney failure. The purpose of this study is to evaluate the use of hypertension drugs in outpatient hypertension patients at Bhayangkara Polda Hospital Lampung. Evaluation of drug use is a quality assurance process in the use of drugs in hospitals aimed at ensuring the drugs used are appropriate, safe and effective. The data collection technique in this study began with the selection process of outpatient medical records who had a primary diagnosis of hypertension. The population in this study were all patient medical records at the Bhayangkara Polda Lampung Hospital in the period of 2020, the use of hypertension drugs based on the right patient was 103 patients, which was 100% correct, the use of Antihypertensive drugs based on the right indication was 103 patients, which was 100% correct. the use of antihypertensive drugs based on the right drug was 82 patients with a percentage (79.61%) of the right drug and as many as 21 patients (20.39%) the wrong drug because the drug given was not in accordance with the standard used, the use of antihypertensive drug was based on the right dose as much as 103 patients were 100% on the right dose, because the dose given was in accordance with the range of antihypertensive drug therapy based on JNC VIII. Keywords: hypertension, drug evaluation, drug use.
FORMULASI LOSION EKSTRAK DAUN SALAM (Syzygium polyanthum) SEBAGAI REPELLENT TERHADAP NYAMUK Aedes aegypti Nopiansyah Nopiansyah; Elia Agustiana
JFL : Jurnal Farmasi Lampung Vol. 12 No. 1 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i1.1020

Abstract

ABSTRACT  Bay leaf is part of the bay plant that contains potentially terpenoid compounds as mosquito's natural repellent. The purpose of this study was to determine the formula composition and effectiveness of repellent n-hexane bay lotion extract with concentrations of 0%, 40%, 50, and 60%. This research is an experimental research. The making of bay leaf extract is used by maceration method. Lotion is made in 4 formulas on the basis of nonionic formula namely FI with extract concentration of 0%, FII with extract concentration of 40%, FIII extract concentration of 50% and FIV with extract concentration of 60%. The results of the non-specific parameter test obtained 2.9% water content, total ash content of 5% and acid insoluble ash content of 0.6% then proceed with organoleptic test, homogeneity, pH, centrifugation, dispersion, viscosity and cycling test. Repellent activity testing is done by counting the number of mosquitoes that alight and not, the average percentage of repellent power of Aedes aegypti at a concentration of 40% is 65.3%, at a concentration of 50% that is 78.6%, and at a concentration of 60% that is 90 8%, the most effective is 60% concentration. From the results of the Anova One Way test, the value of p was 0,000 ≤ 0.05 so it was proven that there were differences in various concentrations of bay leaf extract as repellent to Aedes aegypti mosquitoes. The results of this study indicate that bay leaf extract can be made in a nonionic-based lotion lotion with various concentrations. The physical properties of lotion preparations with variations in bay leaf extract levels did not affect the physical stability of the lotion and did not change during testing and had the effectiveness of mosquito repellent.  Keywords: Aedes Aegypti, N-Hexane,  Repellent, Salam Leaf Extract