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Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS)
Published by Universitas Muhammadiyah Gresik
ISSN : -     EISSN : 27150518     DOI : http://dx.doi.org/10.30587/herclips.v1i02
Core Subject : Health, Science, Social,
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Medicine & Pharmacology Physics Public Health
The purpose of this journal is to facilitate Pharmacist, Scientist, and Researcher to publish research articles or articles reviews. This journal basically contains of topics on Herbal, Pharmaceutical, Clinical, and Sciences. This journal is managing by health faculty Pharmaceutical diploma study program University of Muhammadiyah Gresik
Arjuna Subject : Kedokteran - Biokimia, Kedokteran
Articles 58 Documents
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Pembuatan Produk Camilan Keripik Sehat dan Higienis Berbasis Daun Pepaya (Carica papaya L.) Di UPT Materia Medica Batu Sholikha, Rizkia Ayu; Tiadeka, Pemta; Na’imah, Janatun
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 01 (2019): HERCLIPS VOL 01 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (495.762 KB) | DOI: 10.30587/herclips.v1i01.1022

Abstract

Usually, papaya leaf can be used as malaria disease treatment, prevent acne, appetite enhancer, milk supplement even making a toothache. In this research, papaya leaf is made as snack chips. The ingredients of papaya leaf’s chips are papaya leaf’s, rice flour, tapioca flour, red chili pepper, salt, eggs, guava leaf’s, clay, coriander, candlenut, flavorings, cooking oil, garlic, and water. The papaya chips also treat by organoleptic tests that consist of 5 criteria includes color, smell, texture, appearance, a taste of spices and moisture content test. The process of making papaya leaf’s chips include wash the papaya leaf, cutting, boiling used clay and guava then add salt to remove the bitter taste. The next step is making flour dough, frying, and slicing. The results of the organoleptic test 90% mean that consumers are very like papaya chips and the results of moisture content test are 4.564%.
Analisa Pelayanan Kefarmasian Pada PAsien Rawat Jalan Di Depo Farmasi RSUD IBNU SINA Gresik Berdasarkan Waktu TUnggu Pelayanan Resep Sholikhah, Nur Anisaus; Tiadeka, Pemta; Aisiyah, Siti Nur
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 01 (2019): HERCLIPS VOL 01 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.645 KB) | DOI: 10.30587/herclips.v1i01.1023

Abstract

Usually, response time is a waiting time that counts from patient giving prescription until they receive the medicine. Response time colud influence patients satisfied if took a long time to get the medicine. Besides that, those phenomena could decrease patient satisfaction dan they will think twice to come back to the hospital. Ibnu Sina Hospital tries to increase the pharmacy service with the observation of response time in Depo Pharmacy Pavilion. The purpose of that observation is to optimized pharmacy service by medicine prescription to dispended medicine prescription. This observation is done by retropective methode from January to March 2018. The result of this observation showed that respon time average for medicine prescription is 26 minutes and the average response time for dispende medicine is 36 minutes. This result is suitable with Phramcacautical Service Standart from Kepmenkes No.129/Menkes/SK/II/2008 about prescription services that said respon time for less medicine prescription is than 30 minutes meanwhile for the other one is less than 60 minutes.
Pengaruh Konsentrasi PVA Terhadap Analisa Merkuri Menggunakan MEtode Spektrofotometer UV-Vis Dewi, Listiyana Candra
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 01 (2019): HERCLIPS VOL 01 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.833 KB) | DOI: 10.30587/herclips.v1i01.1012

Abstract

Not all mercury complex compounds can be stable for a long time. Some require additional stabilizers to keep mercury concentrations in the sample unchanged due to interference from outside factors such as measurement time, temperature, humidity, and light. One of the stabilizing compounds commonly used in the analysis of complex compounds is Polyvinyl Alcohol (PVA). Addition of certain substances in the sample solution will have an influence on the character of the sample solution. In this article we will discuss the effect of PVA concentration on the results of analysis of mercury iodide-rhodamine B complex using a UV-Vis spectrophotometer method. The research in this article is experimental. Measurements are made by changing the Hgcation2+ to anion [HgI4]2-. The anion was reacted with rhodamine B and PVA compounds with varying concentrations, then analyzed using a UV-Vis spectrophotometer. The presence of mercury in solution gives rise to new peaks in the wavelength range of 592-606 nm. The concentration of PVA added as a stabilizing agent affects the measurement results. The more concentrated PVA concentration is used, the lower the peak of the mercury iodide-Rhodamine B complex on the spectrum.
Pembuatan Produk Instan Minuman Herbal Bir Pletok Alif, Hefni Henidar; Tiadeka, Pemta
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 01 (2019): HERCLIPS VOL 01 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.561 KB) | DOI: 10.30587/herclips.v1i01.1074

Abstract

Nowaday, people have more attention for their health. They think healthy food or drink came from herbal plant. There are many ways to cultivate plant until they are ready to be harvested. UPT Materia Medica Batu is one of unit that managing plant from cultivate, harvest, making herbal product and analyxing those product. Bir Pletok is one kind of drink that made from ginger, cinnamon,lemongrass,clove, cardamom and secang wood. This herbal drink is believed can imcrease body fit. The purpose of this study is to formulate an acceptable herbal drink as bir pletok. Bir pletok is preparated into two formula (formula I and formula II). The difference between those formula is composition of ginger and secang wood. Sensory analysis is done to determine the panel’s acceptance include colour, taste and aroma characteristic. The result of this research is showed that bir pletok with formula I is getting good colour and taste. It came from secang wood that given interested red colour and low quantity of ginger so giving good taste. There is 15 panelis that participated to Sensory analysis. It can be conclude that 26,6% panelis very liked bir pletok with formula II based on colour. Then 13,3% said very like bir pletok with formula II depend on aroma and taste. This bir pletok formula II is better served hot or cold.
Penerapan Desain Eksperimen Dalam OPtimasi Formula Mikroemulsi Tea Tree Oil Nugraheni, Raditya Weka; Chasanah, Uswatun
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 01 (2019): HERCLIPS VOL 01 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.359 KB) | DOI: 10.30587/herclips.v1i01.1014

Abstract

Microemulsion is a transparent, isotropic and thermodynamically stable preparation. Tea tree oil (TTO) is an essential oil extracted from the leaves of Melaleuca alternifolia by steam distillation which has been proven to have antibacterial and fungal uses. Optimization of microemulsion preparations to obtain preparations with small and stable droplet size is also a challenge. The design of an experiment is to design an experiment with a certain pattern, with a combination of certain input variables that allow to shorten the number of experiments. Based on the research results, it is known that the most influential factor on the microemulsion particle size is the combination of surfactants polysorbate 80 with co-surfactants propyleneglycol.
Perbedaan Pelayanan IGD Berdasarkan Triase Di RUmah Sakit Petrokimia Gresik Sebelum dan Sesudah Adanya Asuransi BPJS Kesehatan Mudalifah, Efa; Ratnasari, Diah
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 01 (2019): HERCLIPS VOL 01 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.547 KB) | DOI: 10.30587/herclips.v1i01.1016

Abstract

Abstract Every hospital has emergency room (IGD) facility for 24 hours. The duty for this section is to give patirnt service with fast respond for emergency health case. In other hand, BPJS give an impact such as differences service in IGD Petrokimia Gresik Hospital. The purpose of this research is to know the different of disease based on triase and to get differences between pharmaceutical supplies in IGD Petrokimia Gresik after getting BPJS insurance. The method of this research is qualitative descriptive. Primer data is used as instrument research such as interview and direct observation. Meanwhile secondary data of this research is IDG documents. The result of this research showed that there was a differences between case or disease that happened in IGD Petrokimia Gresik,not only emergency case that handled in IGD after get BPJS insurance. The second result showed a differences between pharmaceutical supplies after BPJS insurance treatment. Patent medicine had changed to Generic medicine.
Aktivitas Analgesik Ekstrak Etanol Bulu Babi (ECHINOMETRA MATHAEI) Pada Mencit Putih Jantan Lestiono, Lestiono; Kresnamurti, Angelica; Rahmad, Effendi; Ansyori, Muhammad Riko
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 02 (2020): HERCLIPS VOL 01 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v1i02.1352

Abstract

Sea urchin (Echinometra mathaei) is a potential marine resourches that had not been explored widely. It has flavonoid, triterpenoid, alkaloid, saponin compound with high antioxidant activity. Antioxidant activity and flavonoid compound were potentially correlated with analgesic activity. This study aimed to examine e the potential of Echinometra mathaei as an analgesic in white male mice that were induced by acetic acid to produce peripheral pain in vivo (streatching in mice) with writhing test method. The amount of stretching was observed for 1 hour after administration of ethanol extract of Echinometra mathaei orally. Balb/c white mice which devided into 6 groups randomlly, as negative control group, a group that induced acetic acid 1%, Asetosal group with dose of 65 mg/kgBW, and Echinometra Mathaei groups with the dose of 100 mg/kgBW, 200 mg/kgBW, and 400 mg/kgBW. The results of this study showed that all dosage of Echinometra mathaei decrease the peripheral compared to negative control (P,0.05). The percentage inhibition of pain at 200 mg/kgBW (72.59%) was the highest among other doses was significant different from asetosal group (52.53%). This research concluded that Echinometra mathaei has the analgesic activity to inhibit peripheral pain . Keywords: Echinometra mathaei, ethanol extract, analgesic, mice, writhing test
Optimasi Formula dan Uji Antibakteri Terhadap Staphylococcus aureus dan Propionibacterium acne Pada Sediaan Emulgel Kombinasi Minyak Atsiri Cinnamomum Zeylanicum dan Citrus hystrix dengan Desain Faktorial 2^2 Anggraeni, Amaliyah Dina
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 02 (2020): HERCLIPS VOL 01 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v1i02.1410

Abstract

Cinnamon and lime essential oils are known as antibacterial activity. It contains citronellol, geraniol, cinnamaldehyde, and Eugenol. This study aims to determine the concentration of combination Cinnamomum zeylanicum and Citrus hystrix essential oils in emulgel preparations as an antibacterial against Staphylococcus aureus and Propionibacterium acnes. Dosage formulation of emulgel made in various concentrations of combinations of C. Zeylanicum And C. Hystric Essential Oil that 0.5: 2 (FI); 0.5: 4 (FII); 1: 2 (FIII); 1: 4 (FIV) respectively. Further preparation of the emulgel evaluated physical, chemical characteristics, stability during storage, and antibacterial activity. Factorial design 2^2 used to analyze data on the test characteristics of emulgel preparations. The result showed that all formulations have the characteristics of soft, white, and smells of lime and cinnamon. Viscosity, pH, spreadability, freeze-thaw, and real-time temperature stability did not differ significantly. The F3 showed the highest antibacterial activity against Staphylococcus aureus and Propionibacterium acne with a zone of inhibition of 19.10 mm and 19.10 mm, respectively. Variation of C. zeylanicum and C. hystrix essential oils had a significant pH change in the one-month real-time stability test at various temperatures. The antibacterial activity there was no synergistic effect as an antibacterial, which is shown by the absence of interaction between the two active ingredients. Keywords: Cinnamomum zeylanicum, Citrus hystrix, Factorial design, Formulation, Antibacterial
Kitosan Teradiasi Gamma 5 kGy Mempengaruhi Muatan Permukaan Nanopartikel MikroRNA Sumadi, Firasti A.N; Perkasa, DP; Wardana, Tirta; Martien, Ronny; Harjana, Sofia Mubarika
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 02 (2020): HERCLIPS VOL 01 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v1i02.1412

Abstract

Abstract Nanoparticles are non-viral vectors with biodegradability and controlled release abilities that are widely used in gene transfer. Nanoparticles are said to be able to effectively combine and concentrate DNA and RNA in products to be delivered to various cells. Based on changes in microRNA expression in cancer, delivery using microRNA nanoparticles from outside the body is expected to be one of the therapeutic solutions. Irradiated chitosan is assumed to undergo cutting off the main polysaccharide group to produce a smaller molecular weight compared to nonirradiated chitosan. The desired irradiation process to reduce chitosan particle size so that it has better absorption efficiency into the cell needs to be further evaluated including looking at its effect on the final potential zeta. Zeta potential is important to ensure that the nanoparticles are positive enough to be able to enter the negatively charged cell membrane. Chitosan used was irradiated at a dose of 5kGy mixed with 1: 1 nucleic acid ratio. The results of zeta potential measurements showed the highest zeta potential values ​​of 15.27 mV and 13.63 mV obtained in the formula with chitosan-microRNA composition only. The measurement result of zeta potential of irradiated chitosan nanoparticles decreases the surface charge of the particles, this can reduce the potential of nanoparticles for the process of delivery into the cell. Keyword : Irradiated chitosan; nanoparticle; zeta potential
Profil Kesesuaian Penulisan Resep Pada Pasien Umum Eawat Inap Dengan Formularium Di Rumah Sakit Bedah Mitra Sehat Lamongan Nasyanka, Anindi Lupita; Maesaroh, Dewi; Arizka, Hawwin Elina
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 02 (2020): HERCLIPS VOL 01 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v1i02.1414

Abstract

The hospital minimum service standard becomes the minimum reference for assessing the services provided by the hospital. One important point is the suitability of prescribing to patients based on hospital formulary. In this study aims to determine the suitability profile of inpatient prescribing in Rumah Sakit Bedah Mitra Sehat Lamongan with hospital formulary. The research method used was cross-sectional with accidental sampling as many as 614 prescriptions from May until June 2019. The results showed that the percentage of compliance with the average prescribing in May-June did not reach the minimum service standards (100%). therefore, a periodic evaluation of the formulary and outreach is needed to all doctors who write prescriptions for inpatients Keyword : prescribing, hospital formulary, inpatient

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