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Rachmat Hidayat
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INDONESIA
Open Access Indonesian Journal of Medical Reviews
Published by HM Publisher
ISSN : -     EISSN : 28076257     DOI : https://doi.org/10.37275/oaijmr
Core Subject : Health,
Health Professions Medicine & Pharmacology
Open Access Indonesian Journal of Medical Reviews (OAIJMR) is a bi-monthly, international, peer-review, and open access journal dedicated to various disciplines of medicine, biology and life sciences. The journal publishes all type of review articles, narrative review, meta-analysis, systematic review, mini-reviews and book review.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 90 Documents
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Screening of Psychiatric Disorder on Plastic Surgery Patients Angeline Fenisenda
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 5 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i5.48

Abstract

Psychiatric disorders can be found pre-existing in people who seek plastic surgery or due to unsatisfied results. This literature review aimed to describe the screening of psychiatric disorders in plastic surgery patients. Using a preoperative assessment tool to identify patients with underlying psychiatric issues, inappropriate motivations, or unrealistic expectations, as well as to provide a reason for psychological referral, may help avoid such situations. Such a tool would not replace formal in-depth assessment but would alert the medical team of needing further evaluation and possible psychological consultation. Body dysmorphic disorder (BDD) is under-detected in patients presenting for cosmetic surgery, and patients with BDD are highly likely to seek cosmetic surgery. Valid and valuable screening and diagnostic instruments for BDD are available. A simple screening questionnaire (BDDQ) should be used, followed by administration of the BDD SCID for a fraction of patients with a BDDQ-positive screen result to be valuable tools to identify these patients. In conclusion, there was variable psychiatric screenings prior plastic procedure. Some adaptational screening methods will help if there is no proper guideline in the country.
Herbal Medicines as Cancer Treatment: A Narrative Literature Review Awan Rochaniawan
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 5 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i5.49

Abstract

Cancer is a devastating disease that affects millions of people around the world. Despite significant advances in cancer treatment over the years, including chemotherapy, radiation therapy, and surgery, many patients still experience significant side effects and poor outcomes. As a result, there has been growing interest in alternative and complementary therapies, including herbal medicine. Herbal medicine, also known as botanical medicine, is the use of plants and plant extracts for medicinal purposes. This practice has been used for thousands of years and is still commonly used in many cultures around the world. In recent years, there has been growing interest in the use of herbal medicine as a cancer treatment. Many herbs and plant extracts have been found to contain compounds that have anti-cancer properties. These compounds can help to kill cancer cells, prevent the growth and spread of tumors, and reduce the side effects of cancer treatment.
Herbal Medicine for Burns Injury: A Narrative Literature Review Yufimar Riza Fadilah
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 5 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i5.50

Abstract

Traditional medicine uses various phytochemicals for wound healing, supplying enhanced healing processes via anti-inflammatory or antioxidant activity. This literature review aimed to describe herbal medicine for burn injuries. The main stages of the recovery process for burned skin include the migration of blood cells from deep within the burn wound, the promotion of local inflammation, the removal of cellular debris and pathogens, the proliferation of connective tissue and extracellular matrix, the neovascular network (angiogenesis) and tissue remodeling. Therefore, the ideal medicine for burn patients should have excellent wound healing potential and show positive effects at different stages of wound repair. The antioxidant activity is a good option for treating burns. Topical antimicrobial therapy is one of the most essential methods of burn wound care. The ideal antibacterial agent for wound infection prevention and control should directly kill pathogens and reduce local inflammation and tissue destruction. Therefore, herbal products can be used successfully to treat wounds. In conclusion, herbal medicine is recommended to conduct advanced clinical and pharmaceutical research to produce new natural medicines for treating burn wounds.
Surgical Outcomes of Patients with Mental Illness: A Narrative Literature Review Muhammad Rizqi Firyal
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 5 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i5.51

Abstract

Patients with mental illness face numerous limitations when facing surgical treatment. Some of the most significant limitations include difficulty managing their mental health conditions, increased risk of complications, limited access to health facilities, anxiety and limited communication. This literature review aimed to describe the various challenges that patients with mental illness face when undergoing surgery, the impact of mental illness on surgical outcomes, and strategies to improve outcomes for this patient population. Healthcare providers can also improve outcomes by addressing the unique needs of patients with mental illness during the surgical process. This may include developing specialized protocols for anesthesia and pain management, providing additional support and monitoring during and after surgery, and ensuring that patients receive appropriate follow-up care. In conclusion, surgical outcome in patients with mental illness is a complex and challenging issue. Patients with mental illness face numerous challenges during and after surgery, including limited access to appropriate care, increased risk of complications, and difficulty managing their mental health conditions.
An Overview of Syzygium Polyanthum (Bay leaf) Extract as Dyslipidemia Treatment Satya Agusmansyah
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 5 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i5.52

Abstract

Dyslipidemia is one of the main risk factors for cardiovascular diseases, such as heart attack and stroke. This condition can be caused by genetic factors, unhealthy lifestyles (such as unhealthy food, lack of exercise, smoking, and excessive alcohol consumption), as well as some medical conditions, such as diabetes and hypothyroidism Syzygium polyanthum or also called Indonesian bay leaf is a tropical plant that usually grows in Southeast Asia. This literature review aimed to describe the benefits of bay leaves as adjuvant therapy in dyslipidemia. Apart from being used as a spice in cooking, Syzygium polyanthum is also known to have several health benefits. These leaves contain compounds such as eugenol, tannins, and flavonoids, which have antioxidant and anti-inflammatory effects. Several studies show that bay leaves can help lower blood sugar levels, improve heart health, and strengthen the immune system. In conclusion, bay leaf or Syzygium polyanthum has various kinds of compounds, such as flavonoids, eugenol, and tannins which are useful in lowering blood cholesterol. Its use as a therapy for dyslipidemia requires further study.
Pharmacogenetics in Anesthesia Drugs: A Narrative Literature Review Al Maariz Ridhuwan
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.53

Abstract

Pharmacogenetics plays an essential role in genetic variations, which are responsible for causing a variable drug response and include the genetic polymorphism of drug transporters, drug-metabolizing enzymes, and drug receptors. This literature review aimed to describe pharmacogenetics in anesthesia drugs. Human gene-disease studies fall into two general classes; linkage studies and association studies, based on the nature of the inheritance pattern. Linkage studies are used in Mendelian disease, often in families with a high prevalence of a single disease observed early in life, in whom multigenerational trees of inheritance of disease can be traced. In conclusion, pharmacogenetics is in the initial stage of clinical practice. Its contribution to new drug development will likely become a reality. Common polymorphisms in drug targets dictate that DNA sequence variations will be considered in the genomic screening processes for new drug development. This will provide new insights for developing medications that target critical pathways in disease pathogenesis and medications that can be used to prevent diseases in individuals genetically predisposed to them.
The Pharmacogenetics of Metformin: A Narrative Literature Review Alrahman Joneri
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.54

Abstract

Metformin is one of the used medications for the treatment of type 2 diabetes. It works by reducing glucose production in the liver and improving glucose uptake and utilization in peripheral tissues. the pharmacogenetics of metformin is a rapidly evolving field with potential implications for personalized medicine. This review aimed is to explore the pharmacogenetics of metformin, including the genetic variants that may influence its efficacy and safety, as well as the potential implications for clinical practice. Genetic testing may be useful in identifying patients who are likely to benefit from metformin and those who are at higher risk for adverse effects. However, the implementation of genetic testing for metformin response in clinical practice faces several challenges, including cost, interpretation of test results, and the need for further evidence of clinical utility. In conclusion, the pharmacogenetics of metformin is a rapidly evolving field with potential implications for personalized medicine.
Obstetric Management in Maternal with COVID-19: A Narrative Literature Review Asoly Giovano
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.55

Abstract

The incidence of COVID-19 in pregnant women varies by geographic region and population. However, pregnant women may be at an increased risk of COVID-19 infection compared to non-pregnant women. Several risk factors have been identified for severe COVID-19 illness in pregnant women, including maternal age, obesity, chronic medical conditions, ethnicity, gestational age, and multiple pregnancies. Screening and testing for COVID-19 in pregnant women is essential to prevent transmission and ensure appropriate management. Pregnant women should be screened for symptoms at each prenatal visit, and those with symptoms or high-risk exposures should be tested using a PCR-based assay. Repeat testing may be necessary in certain situations, and universal testing may be implemented in some healthcare facilities. Antibody testing is not currently recommended for diagnosis or management of pregnant women. The delivery management of pregnant women with COVID-19 should be individualized based on the severity of the illness, gestational age, and fetal status. The neonatal management of infants born to mothers with COVID-19 should focus on the prevention of transmission and optimization of neonatal outcomes. Neonates should be evaluated for COVID-19 using a PCR-based assay, and respiratory support should be provided.
Review of Genetic Variants of Butyrylcholinesterase and Their Potential Impact on Human Health Nugraha, Bharmatisna Anggaharsya
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.56

Abstract

Butyrylcholinesterase (BChE) is an enzyme found in plasma and many other parts of the body. It is enzyme that hydrolyses drugs containing ester bonds such as drugs acting at the neuromuscular junction (succinylcholine) and local anaesthetics (procaine). Examination of the gene for mutations or polymorphisms causing the observed biochemical phenotypes has isolated those responsible for all the most widely known variants. The molecular bases of several genetic variants of BChE have been reported, such as the Atypical variant, fluoride-resistant variant, silent variant, K variant, J variant and C5 variant. In general, BChE polymorphisms have been shown to produce enzymes with varying levels of catalytic activity. Genetic variants of human butyrylcholinesterase were one of the first examples in the new field of pharmacogenetics when it was recognized that abnormal response to the succinylcholine was due to a mutated enzyme with low binding affinity. Beside that, variant of BChE has potential impact for Alzheimer disease patology.
Ethics in Gene Editing Diana, I Made
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.57

Abstract

For thousands of years, humans have felt the need to understand the world around them—and ultimately manipulate it to best serve their needs. There are always ethical questions to address, especially when the manipulation involves the human genome. There is currently an urgent need to actively pursue those conversations as com- mercial gene sequencing and editing technologies have become more accessible and affordable. Gene Editing has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, gene editing has been strongly resisted.

Page 3 of 9 | Total Record : 90

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