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Jurnal Sains dan Kesehatan

jsk
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Published by Universitas Mulawarman

ISSN : 23030267 EISSN : 24076082 DOI : https://doi.org/10.25026/jsk

Core Subject : Health, Science, Agriculture,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Jurnal Sains dan Kesehatan (J. Sains. Kes) (e-ISSN 2407-6082, p-ISSN 2303-0267), is a national journal with ISSN and published four times a year in 2015. In 2016 the publishing frequency changed to twice a year. In 2021 the frequency increased to six times a year. Jurnal Sains dan Kesehatan is published online by the Faculty of Pharmacy, Mulawarman University, Samarinda City, East Kalimantan. Since 2019, the Jurnal Sains dan Kesehatan has been accredited to SINTA. Jurnal Sains dan Kesehatan publishes manuscripts (Original research Article, review articles, and Short communication) on original work, either experimental or theoretical in the following areas: Pharmaceutics, Pharmaceutical Chemistry, Pharmacology & Toxicology, Pharmaceutical Biotechnology & Microbiology, Pharmacy practice & Hospital Pharmacy, Case Study & Full clinical trials, Clinical Pharmacy, Medicine, and other related fields. The purpose of publishing the Jurnal Sains dan Kesehatan is to provide scientific information about the development of science and technology in the field of Science and Health. Lingkup naskah Jurnal Sains dan Kesehatan mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan Jurnal Sains dan Kesehatan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 19 Documents

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Search results for , issue "Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan" : 19 Documents clear

Formulasi dan Karakterisasi Nanopartikel Kitosan Ekstrak Sari Buah Juwet (Syzygium cumini) menggunakan metode Gelasi Ionik: Formulation and characterization of Chitosan Nanoparticle of Juwet (Syzygium cumini) Fruit Extract Using Ionic Gelation Method Wahida Hajrin; Wayan Cintya Ganes Budastra; Yohanes Juliantoni; Windah Anugrah Subaidah
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Syzygium cumini (S. cumini) fruits have a high potential to be developed as medicine because of their polyphenol content. Polyphenol is easily degraded so that its stability needs to be increased through the formation of nanoencapsulation. The aim of this study was to determine the formula of SBJ nanoparticles which has good characteristics. The formula was determined using a pseudoternary phase diagram based on the %transmittant and %EE. Nano SBJ was characterized for % transmittant ,% EE, polydispersity index, and zeta potential. The formula of Nano SBJ obtained chitosan, SBJ extract, and Na TPP were 0.347%, 0.627%, and 0.047%, respectively. The characterization of Nano SBJ were % EE was 30.72%, the mean diameter of particles was 138.1 ± 7.9 nm, PdI was 0.839 ± 0.043, and zeta potential was 34.9 ± 1.2 mV. Nano SBJ has nano-sized particles and has good stability, but low in entrapment efficiency.

Uji Aktivitas Antibakteri Hasil Fermentasi Bakteri Endofit Umbi Talas (Colocasia esculenta L) terhadap Bakteri Pseudomonas aeruginosa : Potential of Antibacterial Compound Fermentation of Endophytic Bacteria from Taro Tuber (Colocasia esculenta L.) againts Pseudomonas aeruginosa Desi Purwaningsih; Destik Wulandari
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Bacterial endophyte is an endosimbiont which lives within host plans without causing apparent disease on its host plans. Some endophytic bacteria found in plants have the capability to produce potential compounds as antibacterial. This study aimed to determine the antibacterial activity of the endophytic bacteria fermentation from the tubers of taro plants and determine the optimum time of fermentation which produce the highest antibacterial activity. This research was initially started by producing the suspension of the endophytic bacteria and test bacteria. The suspension that had been made then was used to characterize and identify the endophytic bacteria and test bacteria. Identification methods include colony identification, Gram staining, Spore staining and biochemical tests planted on MCH, SIM, LIA and Citrate mediums. The fermentation was then carried out to produce secondary metabolite compounds which were utilized to examine the antibacterial activity against Pseudomonas auriginosa. The antibacterial activity test was conducted by the disk diffusion assay. The results of the antibacterial activity assay showed that Bacillus siamenssis and Bacillis subtilis were both able to produce secondary metabolites that have potential as antibacterial against Pseudomonas earuginosa. The highest value was achieved by 72 hours fermentation time with a value of 8.7 by Bacillus siamensis. The endophytic bacteria Bacillus subtilis had the highest activity value at 48 hours fermentation time with an average of diameter of inhibition zone of 8.97.

Hubungan Usia dengan Stadium Saat Diagnosis Penderita Kanker Kolorektal di RSUD Abdul Wahab Sjahranie Samarinda: Relationship of Age and Stadium when Diagnosed of Cholorectal Cancer at RSUD Abdul Wahab Sjahranie Samarinda Sri Jatul Zannah; Ignatia Sinta Murti; Sulistiawati Sulistiawati
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Abstract Background: Colorectal cancer is a malignancy originating from the colon tissue. The incidence of colorectal cancer was recorded at 396,914 new cases with 234,511 deaths and the fourth rank of all types of cancer cases in Indonesia. This study aims to determine the relationship between age and histopathological features and stage when diagnosed with colorectal cancer at Abdul Wahab Sjahranie Hospital, Samarinda. Methods: The study design was retrospective analytic with a cross sectional study approach. The research data came from the medical records of colorectal cancer patients at Abdul Wahab Sjahranie Hospital, Samarinda in 2017-2020. Results: A total sample size of 71 samples. Data analysis statistically showed the relationship between age and stage at diagnosis with p = 0.004 (p = 0.05). Conclusion: The relationship between age and stage at diagnosis of colorectal cancer patients at Abdul Wahab Sjahranie Hospital, Samarinda. Keywords: Colorectal Cancer, Age, Stage

Aktivitas Fisik dan Risiko PPOK pada Pengemudi Becak di Surabaya: Physical Activities and COPD Risks in Pedicab Drivers in Surabaya Amelia Lorensia; Rivan Virlando Suryadinata; Noer Lailatul Istiqomah; I Nyoman Yoga Diputra
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Pedicab drivers have low economic level and smoking is a social habit that very risk of experiencing lung function disorders, but are also classified as having routine physical activity while pedaling the rickshaw. The purpose was to determine physical activity and risk of COPD from the value of lung function in pedicab drivers in Surabaya. The research design was cross-sectional research in March-December 2018. The location used was in the vicinity of the Surabaya area. The research variables included: pulmonary function disorders by measuring spirometry and physical activity using the International Physical Activity Questionnaire (IPAQ). The data analysis was descriptive. The total respondents were men, amounting to 188 people. Most of the respondents had moderate lung function disorders at 82.45%. Respondents with impaired lung function had high physical activity profile of 1 person (0.61%); moderate physical activity profile was 155 people (95.09%) and and low physical activity profile was 7 people or 4.29%. Respondents with non-impaired lung function have a moderate physical activity profile of 25 people (100%). Therefore, it was necessary to further research the factors that can affect the decline in lung function of pedicab drivers in addition to physical activity.

Hubungan antara Penyakit Arteri Perifer dan Kadar Hba1c dengan Tindakan Amputasi Ekstremitas pada Pasien Ulkus Kaki Diabetik di RSUD Abdul Wahab Sjahranie Samarinda: Relationship between Peripheral Arterial Disease and HbA1c Levels with Amputation of Extremities in Diabetic Foot Ulcer Patients at Abdul Wahab Sjahranie Hospital Samarinda Ayu Wira Oktalia; Yuliana Rahmah Retnaningrum; Siti Khotimah
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Ulkus kaki diabetik adalah luka kronik pada daerah di bawah pergelangan kaki, yang meningkatkan morbiditas, mortalitas, dan mengurangi kualitas hidup pasien. Prevalensi penderita diabetes melitus dengan ulkus kaki diabetik di Indonesia sekitar 15% dan angka amputasi penderita ulkus kaki diabetik 30%. Dengan mengontrol kadar HbA1c, perkembangan neuropati diabetik dan penyakit arteri perifer yang merupakan faktor risiko amputasi ektremitas dapat dicegah. Penelitian ini bertujuan untuk mengetahui ada tidaknya hubungan antara penyakit arteri perifer dan kadar HbA1c dengan tindakan amputasi ekstremitas pada pasien ulkus kaki diabetik di RSUD Abdul Wahab Sjahranie Samarinda. Desain penelitian yang digunakan adalah studi analitik observasional potong lintang dengan pendekatan retrospektif. Sampel dipilih secara acak sederhana sebanyak 49 sampel. Data sampel diperoleh dari data rekam medis di RSUD Abdul Wahab Sjarharnie tahun 2017-2020. Uji statistik yang digunakan adalah uji fisher dan uji chi-square. Hasil penelitian ini menunjukkan bahwa tindakan amputasi pada pasien ulkus kaki diabetik memilki hubungan yang signifikan secara statistik dengan penyakit arteri perifer (p = 0,022; PR = 2,925; 95%CI = 1,316 – 6,501) dan kadar HbA1c (p = 0,024; PR = 4,138; 95%CI = 1,037 – 16,519).

Pengaruh Irama Sirkadian Terhadap Memori Jangka Pendek pada Mahasiswa Fakultas Kedokteran Universitas Mulawarman: The Effect of Circadian Rhythm on Short-Term Memory in Medical Study of the Medical Faculty of Mulawarman University Muhammad Fachrian Akbar; Agustina Rahayu Magdaleni; Hary Nugroho; Endang Sawitri; Arie Ibrahim
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

ABSTRACT Short-term memory is a form of cognitive function to store information in a short time, which is important to support daily work and learning activities. Circadian rhythm is a physical, mental, and behavioral changes that occurs in 24-hour daily cycle which is believed to be a factor that affecting short term memory , for example sleep-wake cycle. This study was aimed to determine the effect of routinity of aerobic on short-term memory in students at the Faculty of Medicine, University of Mulawarman. This analytic observational study with cross-sectional method used 94 male respondents at the Faculty of Medicine, Mulawarman University, consisting of the Medical Study Program, Dentistry Study Program, and Nursing with stratified random sampling technique. The research results showed the most circadian rhythm type is night chronotype as many as 71 people (76%) (p=0.031). Short-term memory scores were obtained by 41 people (44%) on good category and 53 people (56%) on bad category. It was concluded that there is an effect of circadian rhythm on short-term memory in Medical Study of The Medical Faculty of Mulawarman University. Keyword : Circadian rhythm, Short-term memory, Medical student, Scenery Picture Memory Test (SPMT) ABSTRAK Memori jangka pendek merupakan bentuk fungsi kognitif untuk menyimpan informasi yang tersedia dalam waktu yang singkat dimana hal ini penting untuk menunjang aktivitas pekerjaan maupun pembelajaran sehari-hari. Irama sirkadian adalah suatu perubahan fisik, mental, dan perilaku yang tejadi mengikuti siklus harian 24 jam yang diyakini sebagai faktor yang mempengaruhi memori jangka pendek, contohnya seperti siklus bangun tidur. Penelitian ini bertujuan untuk mengetahui pengaruh aerobik rutin terhadap memori jangka pendek pada mahasiswa di Fakultas Kedokteran Universitas Mulawarman. Penelitian observasional analitik dengan metode potong lintang ini menggunakan 94 responden laki-laki di Fakultas Kedokteran Universitas Mulawarman yang terdiri atas Program Studi Kedokteran, Program Studi Kedokteran Gigi, dan D3 Keperawatan dengan menggunakan teknik stratified random sampling. Hasil penelitian menunjukan tipe irama sirkadian terbanyak ialah kronotipe malam yaitu 71 orang (76%) dengan nilai p = 0,031. Nilai memori jangka pendek didapatkan 41 orang (44%) dalam kategori baik dan 53 orang (56%) kategori tidak baik. Disimpulkan bahwa terdapat pengaruh irama sirkadian terhadap memori jangka pendek pada Mahasiswa Fakultas Kedokteran Universitas Mulawarman. Kata Kunci : Irama sirkadian, Memori jangka pendek, Mahasiswa kedokteran, Scenery Picture Memory Test (SPMT)

Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Editor Jurnal Sains dan Kesehatan
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Rancang Bangun Pendeteksi Kadar Formalin pada Mie Basah Menggunakan Sensor Warna TCS3200 : Design and Development of Formalin Contents Detection in Wet Noodles using Color Sensor TCS3200 Rani Laras Wati; Endang Rosdiana; Valentina Adimurti Kusumaningtyas
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Wet noodles have a short shelf life because they are spoiled more quickly by microorganisms. Therefore, some irresponsible wet noodle producers add formalin so that the noodles can last longer. However, formalin is a substance that is prohibited from being used because it is dangerous to health. In this research, an instrument has been made that can detect formalin levels in wet noodles which have formalin concentrations of 0 ppm, 40 ppm, 95 ppm and 150 ppm. The instrument consists of a TCS3200 color sensor and an ATmega328P microcontroller. The color detected by the TCS3200 sensor is the color from mixing the formalin wet noodle sample withreagent schiff's. Furthermore, the sample will be selected by the instrument based on the RGB color value detected by the TCS3200 color sensor. The test results obtained the reliability of the instrument in selecting the sample of formalin wet noodles with a concentration of 0 ppm worth 92.5%, 40 ppm worth 95%, 95 ppm worth 97.5% and 150 ppm worth 100%.

Jumlah Koloni Streptococcus mutans pada Anak Asma dengan Pemberian Probiotik Lactobacillus reuteri : Total Colony of Streptococcus mutans in Asthmatic Children with Feeding Probiotics Lactobacillus reuteri Nydia Hanan; Teguh Budi Wibowo; FX Suhariadji
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Beberapa kondisi kesehatan gigi dan mulut sering dikaitkan dengan asma yang diderita oleh anak-anak. Salah satunya adalah meningkatnya kejadian karies gigi serta penurunan produksi saliva, juga perubahan kondisi rongga mulut yang berpeluang menyebabkan terjadinya karies. Tujuan penelitian ini adalah untuk mengetahui jumlah koloni Streptococcus mutans pada anak asma yang diberi pakan probiotik Lactobacillus reuteri. Penelitian ini melibatkan empat belas subjek berusia 9-12 tahun, tujuh anak penderita asma dan tujuh anak non-asma (kelompok kontrol). Plak subjek diambil kemudian dihitung koloninya. Setelah pengambilan plak, sampel diminta untuk meminum tablet probiotik dua kali sehari setelah makan. Dilakukan selama 2 minggu. Perhitungan jumlah koloni Streptococcus mutans sebelum dan sesudah pemberian tablet hisap probiotik pada anak kelompok asma dan kelompok kontrol. Rerata jumlah Streptococcus mutans sebelum pemberian probiotik pada anak penderita asma yaitu 23,71x104 CFU/ml dan setelah pemberian probiotik 10,14x104 CFU/ml. Sedangkan pada kelompok kontrol (non-asma), jumlah Streptococcus mutans sebelum pemberian probiotik adalah 14,29 x104 CFU/ml dan setelah pemberian probiotik 9,43x104 CFU/ml. Lactobacillus reuteri probiotik tablet hisap dapat menurunkan jumlah Streptococcus mutans di rongga mulut anak penderita asma.

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Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

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+6285222221907

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admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Rolan Rusli

Contact Email rolan@farmasi.unmul.ac.id

Phone +6285222221907

Journal Mail Official admin@farmasi.unmul.ac.id

Editorial Address Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location Kota samarinda, Kalimantan timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA