Pediatric Sciences Journal
Pediatric Sciences Journal (PedSciJ) is published by the Medical Faculty of Brawijaya University, Indonesia, as an Open Access & Peer Reviewed Multidisciplinary Journal. The aims and scope of the Journal include pediatric, neonatal healthcare, and perinatology/ The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions that promote the exchange of ideas and rational discourse between practicing educators and medical researchers worldwide. Pediatric Sciences Journal (PedSciJ) publishes peer-reviewed clinical research articles, case reports, serial case reports, systematic reviews, meta-analyses, and letters to the editor twice a year in June and December. Articles published in the Pediatric Sciences Journal (PedSciJ) embrace the full scope of the manuscript related to the health and diseases of infancy, neonates, children, adolescents, and those related to pediatric topics. The Journal also explores legal and ethical issues, neonatal technology, and product development based on COPE. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians, pediatric subspecialists, obstetrics, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists
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<![CDATA[Relationship between inhaled steroids and anthropometric status of pediatric patients with chronic asthma ]]>
<![CDATA[Harjoedi Adji Tjahjono]]>;
<![CDATA[Ery Olivianto]]>;
<![CDATA[Alfidha Muntaz]]>;
<![CDATA[Irfan Agus Salim]]>;
<![CDATA[Fadilah mutaqin]]>
<![CDATA[ Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023) ]]>
Publisher : <![CDATA[Medical Faculty of Brawijaya University, Indonesia ]]>
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DOI: 10.51559/pedscij.v4i1.53
<![CDATA[Background: Asthma is a chronic inflammatory respiratory disease characterized by breathlessness, wheezing, and coughing symptoms. Asthma management aims to control the frequency of asthma exacerbations and ensure optimal growth and development in children. Inhaled steroids are anti-inflammatory medications that inhibit the synthesis of pro-inflammatory cytokines such as IL-4, IL-9, IL-13, and IL-17, which play a role in the pathogenesis of asthma. However, using inhaled steroids at high doses and for a long duration can have side effects on children's height. This research aims to examine the relationship between the use of inhaled steroids and the growth in height of children with asthma. Methods: simple linear regression analysis and multiple linear regression analysis. Results: the analysis indicate a correlation between daily dose and height increment in children aged 5-10 years (p = 0.005 < 0.05), but no significant correlation was found in children aged 10-18 years (p = 0.722 > 0.05). The analysis of total duration shows a correlation with height increment in both age groups (5-10 years, p = 0.035 < 0.05; 10-18 years, p = 0.001 < 0.05). The analysis also reveals a correlation between the simultaneous total duration and total dose with height increment in both age groups (5-10 years, p = 0.005 < 0.05; 10-18 years, p = 0.008 < 0.05). Conclusion: this study found a correlation between daily dose and height in both age groups, a correlation between total duration and height in the 5-10-year-old age group, and a correlation between simultaneous total duration and total dose with height in both age groups.]]>
<![CDATA[The correlation between levels of vitamin D (25(HD)D) and the occurrence of necrotizing enterocolitis (NEC) in preterm infants ]]>
<![CDATA[Eko Sulistijono]]>;
<![CDATA[Brigitta Ida Resita Vebrianti Corebima]]>;
<![CDATA[Yesi Adisti Pramitasari]]>
<![CDATA[ Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023) ]]>
Publisher : <![CDATA[Medical Faculty of Brawijaya University, Indonesia ]]>
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DOI: 10.51559/pedscij.v4i1.48
<![CDATA[Introduction: One of the causes of gastrointestinal emergencies in newborns is necrotizing enterocolitis (NEC). A fetus is fully dependent on transfer from the mother as it lacks endogenous 25(OH)D production. Transplacental vitamin D transmission mainly occurs due to the elevated risk of vitamin D insufficiency in preterm newborns during the third trimester of pregnancy. This research is important to raise awareness about the importance of early initial screening of vitamin D levels in preterm infants in Indonesia. Methods: This study used an observational research design which is a cohort study, taking place during March–May 2020 in the neonatology inpatient ward of dr. Saiful Anwar General Hospital Malang. The enzyme-linked immunosorbent assay (ELISA) technique was used to measure the amount of vitamin D in the blood. The Kolmogorov-Smirnov test and the Levene test were used to determine whether the data were normal and homogeneous, respectively. Result: It was found that vitamin D levels in preterm infants with NEC were lower (10.18 ± 4.07 ng/mL) than in preterm infants without NEC (16.95 ± 4.45 ng/mL). The bivariate analysis result showed that vitamin D deficiency increased the risk of NEC by 10.7 times with p-value = 0.033 (95% CI 1.2-24.9). Furthermore, multivariate analysis found that vitamin D deficiency increased the occurrence of NEC by 19.4 times with a p-value = 0.043 (95%CI 0.7-21.7) and respiratory distress could increase the incidence of NEC by 9.4 times with a p-value =0.02 (95%CI 1.2-70). Conclusion: Vitamin D (25(OH)D) levels were lower in preterm infants with necrotizing enterocolitis compared to preterm infants without necrotizing enterocolitis. This study showed a significant correlation between vitamin D(25(OH)D) levels and the case of necrotizing enterocolitis in preterm infants.]]>
<![CDATA[Coronavirus disease 2019 (COVID-19) and polyarthritis juvenile idiopathic arthritis (JIA) comorbidity in children at emergency Wisma Atlet Kemayoran: the first case report with two months follow up ]]>
<![CDATA[Nia Fitriyani]]>;
<![CDATA[Fitria Mahrunnisa]]>;
<![CDATA[Tiona Romauli]]>
<![CDATA[ Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023) ]]>
Publisher : <![CDATA[Medical Faculty of Brawijaya University, Indonesia ]]>
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DOI: 10.51559/pedscij.v4i1.50
<![CDATA[Background: Infection with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is often mild and asymptomatic in youngsters. However, in other circumstances, such as juvenile rheumatoid arthritis (JRA), COVID-19 necessitates special consideration because of the general immune system harm associated with autoimmune disorders and the iatrogenic side effects of corticosteroids. The multisystem inflammatory syndrome in children (MIS-C), which manifests 4-6 weeks after infection as a high fever, organ dysfunction, and markedly elevated markers of inflammation, is one manifestation of the COVID-19 disease that can cause secondary vasculitis or present with vasculitis or hyperinflammation manifestations. The association between MIS-C and SARS-CoV-2 infection shows that post-infectious immunological dysregulation plays a role in the pathogenesis. This study aimed to present a case of COVID-19 and JRA comorbidity in children at emergency Wisma Atlet Kemayoran. Case Report: A 10-year-old boy was admitted to COVID-19 Emergency Hospital Wisma Atlet Kemayoran with complaints of anosmia. The patient had a history of polyarthritis JRA, has been diagnosed since January 2020 and has routinely received methylprednisolone 4 mg/day and one tablet of calcium lactate once daily. No abnormalities were discovered during a general physical examination or a Pediatric Gait, Arms, Legs, and Spine (pGALS) assessment. On laboratory testing, leukocytosis and thrombocytosis are present. Thorax and extremities were radiologically examined within acceptable bounds. According to national guidelines for mild COVID-19 in children, the patient got routine treatment, which included a multivitamin. The patient also continued receiving methylprednisolone and calcium lactate while he was treated. After 12 days of treatment, the patient tested negative for COVID-19. One month after treatment, there was no hyperinflammatory reaction or recurrence of JRA. Conclusion: In pediatric patients diagnosed with COVID-19 and JRA, it is important to continue corticosteroid treatment with an adjusted dose. Even though this treatment has the possibility of causing immunosuppression which can complicate the healing process of COVID-19, we need to prevent the recurrence of JRA in patients.]]>
<![CDATA[Correlation of Vitamin D and nutritional status in pediatric systemic lupus erythematosus ]]>
<![CDATA[Muhammad Zulfikar Mahfudz]]>;
<![CDATA[Harjoedi Adji Tjahjono]]>;
<![CDATA[Irfan Agus Salim]]>;
<![CDATA[Fadilah Mutaqin]]>
<![CDATA[ Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023) ]]>
Publisher : <![CDATA[Medical Faculty of Brawijaya University, Indonesia ]]>
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DOI: 10.51559/pedscij.v4i1.56
<![CDATA[Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune illness affecting various organ systems, including the skin, joints, kidneys, cardiovascular, and neurological systems. Because of its immunomodulatory properties, vitamin D has been linked to the etiology and therapy of SLE. The link between vitamin D and nutritional status in pediatric systemic lupus erythematosus (pSLE) is complicated and multifaceted. This study aims to see if there is a link between vitamin D and nutritional status in children with systemic lupus erythematosus. Method: This study design was cross-sectional to determine factors influencing children with SLE. The study was conducted at Saiful Anwar Hospital in Malang from January 1, 2021, to June 30, 2022, and was approved by the hospital's research ethics committee. Statistical analysis was performed using the Shapiro-Wilk test for normality and Pearson correlation with SPSS 25 statistical analysis software. Results: All samples (32 children) were female, with a mean age of 14.1 ± 1.5 years. The mean vitamin D level was 18.32 ± 2.15 ng/mL, mean body mass index (BMI) was 19.51 ± 1.49 kg/m2. Regarding the nutritional status of children with SLE, 10 children were classified as malnourished (30%), while 19 children had good/normal nutritional status (60%). Three children had overweight (10%). There was a positive correlation between BMI and vitamin D in children with SLE (p=0.000, r=0.630). Conclusion: The majority of SLE youngsters have inadequate vitamin D levels. Vitamin D and the nutritional health of children with pediatric systemic lupus erythematosus have a significant favorable association.]]>
<![CDATA[Global impact of climate change on children's health in the world ]]>
<![CDATA[Kurniawan Taufiq Kadafi]]>;
<![CDATA[Dimas Dwi Saputro]]>;
<![CDATA[Martinus Martin Leman]]>;
<![CDATA[Aslinar]]>;
<![CDATA[Badai Buana Nasution]]>;
<![CDATA[Dimas Tri Anantyo]]>;
<![CDATA[Niken Wahyu Puspaningtyas]]>;
<![CDATA[Fathy Zuandy Pohan]]>;
<![CDATA[I Nyoman Arie Purwana]]>;
<![CDATA[Muhammad Reza]]>;
<![CDATA[Jaya Ariheryanto Effendy]]>;
<![CDATA[Yogi Prawira]]>;
<![CDATA[Piprim Basarah Yanuarso]]>
<![CDATA[ Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023) ]]>
Publisher : <![CDATA[Medical Faculty of Brawijaya University, Indonesia ]]>
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DOI: 10.51559/pedscij.v4i1.57
<![CDATA[Climate change has a close relationship with the greenhouse effect. The greenhouse effect is needed by the earth, but if there are too many greenhouse gases in the atmosphere this will increase the earth's temperature. Children are a group of people who have a high vulnerability to climate change. Climate change will affect children's health through 4 impacts, namely direct impacts on children's health, impacts on children's health through ecosystems, impacts on children's health through human behavior, and health impacts on children due to natural disasters. To anticipate the impact of climate change on children's health, parents and the government must take anticipatory steps so that children can be saved from the extreme dangers of climate change.]]>
<![CDATA[Relationship between vitamin D levels with nutritional status and children's obesity in Saiful Anwar Hospital, Malang ]]>
<![CDATA[Anik Puryatni]]>;
<![CDATA[Harjoedi Adji Tjahjono]]>;
<![CDATA[Hanna Tetty]]>
<![CDATA[ Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023) ]]>
Publisher : <![CDATA[Medical Faculty of Brawijaya University, Indonesia ]]>
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DOI: 10.51559/pedscij.v4i1.59
<![CDATA[Background: Obesity is a condition marked by an excessive buildup of body fat tissue and is characterized by a recognizable clinical picture. An imbalance between energy intake and energy output leads to obesity. Both obesity and vitamin D insufficiency are serious health issues of the present. It was claimed that the mobilization of free fatty acids from adipose tissue might be impacted by active vitamin D (1,25-dihydroxy vitamin D). This study aimed to find a relationship between vitamin D levels with nutritional status and children's obesity in Saiful Anwar Hospital. Methods: This study used a cross-sectional approach with a consecutive sampling method. Seventy-five subjects met the inclusion criteria in the Saiful Anwar Hospital Malang pediatric ward in February-March 2022. The samples were then examined for vitamin D levels. Subjects were grouped based on good nutritional status, overweight, and obesity. The basic characteristics of the research subjects included gender, age, anthropometric status, nutritional status, and vitamin D levels. Results: The results showed that vitamin D levels were lower in overweight and obese children (median 17.6 and 14.08 kg/m2) than in normal nutrition children (median 34 kg/m2). Vitamin D and children's nutritional status had a significant relationship (p=0.001). Conclusion: Vitamin D levels and children's nutritional status were significantly correlated, with vitamin D levels being lower in overweight and obese children than in children with normal nutrition.]]>
