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Zahratul Aini
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dr.zahratulaini@unsyiah.ac.id
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INDONESIA
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 11 Documents
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Search results for , issue "JKKI, Vol 9, No 3, (2018)" : 11 Documents clear
HUBUNGAN UMUR, PENDIDIKAN, PEKERJAAN, PARITAS DAN RIWAYAT MASTITIS DENGAN KEJADIAN MASTITIS Anggun Hatto Hanti; Lina Handayani; Azidanti Saufi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art5

Abstract

Background: The national coverage of exclusive breastmilk did not reach its target in 2014. One reason behind this was due to the swelling of the breast to mastitis condition. Hence the baby was not getting enough breastmilk. World Health Organization WHO estimates the mastitis case between 2.6 and 33 %, with global prevalence around 10% of all breastfeeding women. In 2014, Panembahan Senopati Bantul Yogyakarta Hospital documented 5.3% women with mastitis and 4.2% in 2015. Objective: This research aims to evaluate the correlation of ages, education, employment status, parity, and mastitis history with mastitis case in Panembahan Senopati Bantul Yogyakarta Hospital.Methods: This research was an observational analytic with a case-control design. Data analytic was performed using the Chi-Square test. Results: The results of bivariate analysis showed that age (OR = 0.673; 95% CI; 0.345-1.314), education (OR = 1.288; 95% CI; 0.678-2.44), employment status (OR = 1.368; 95% CI; 0.749 -2.497), and parity (OR = 0.829; CI 95%; 0.455-1.511) did not have a significant correlation with the incidence of mastitis, but the history of mastitis showed a significant association with the incidence of mastitis (OR = 2.280; 95% CI; 1.112-1.674 ). Conclusion: There was a correlation between the history of mastitis with the recurrence of mastitis in Panembahan Senopati Bantul Yogyakarta Hospital.
Formulation peel-off gel mask of Impatiens balsamina l. as an antibactery against Staphylococcus aureus Fitriani Mahyun; Aris Perdana Kusuma; Hady Anshory
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art6

Abstract

Background: Acne is a skin disorder characterised by inflammation, accompanied by a blockage of the oil glands in the skin. One of the causes of acne is Staphylococcus aureus bacteria. Many plants have been widely studied as an antibacterial agent, including Garden Balsam Leaf (Impatiens balsamina L.) which could be formulated in a peel-off gel preparation.Objective : The purpose of this research was formulating an antibacterial peel-off gel mask with a variation of viscosity enhancing agent hydroxypropyl methylcellulose (HPMC), as well as testing its antibacterial activity on Staphylococcus aureus.Methods : HPMC 1-2% was formulated in peel-off gel mask of Garden Balsam leaf extract. Physical properties such as viscosity, pH, spreadability, and drying time were tested, while antibacterial activity test was conducted by the agar-diffusion method.Results : The viscosity of the entire formula was > 20,000 cP, pH 6, drying time > 20 minutes, and spreading power > 6 cm. Also, the peel-off gel mask also showed antibacterial activity on Staphylococcus aureus with average inhibition zone were > 10 mm, which indicated strong antibacterial inhibitory power.Conclussion : The concentration variation of HPMC had a significant effect on all physical properties test. HPMC 1.5% in the preparation showed the most optimum results.
Diagnosis dan Tatalaksana Terkini Penyakit Neurosistiserkosis Michael Carrey; Endy Suseno; Freggy Spicano Joprang; Octavianus Darmawan; Rr. Josephine Retno Widayanti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss3.art9

Abstract

Cysticercosis occurs in porcine naturally. A human can be infected by cysticercosis if they swallow Taenia solium's egg inadvertently. These eggs can be found in vegetables or unboiled water. These eggs hatch and later will become larva that becomes cysts in muscle or brain, known as cysticercus cellulose. Neurocysticercosis is an infection of the central nervous system caused by Taenia solium at its larval stage. Indonesia is a developing country with a high incidence rate of neurocysticercosis, with the highest amount of cases found in Bali and Papua. Neurocysticercosis boasts a broad array of clinical symptoms, from silent disease to a severe, debilitating illness that leads to death. The diagnosis of neurocysticercosis itself presents a great challenge, due to the unspecific clinical symptoms, in-pathognomonic radiographic findings and serologic studies with low specificity and sensitivity. The management of neurocysticercosis consists of a combination of antiparasitic agents and supportive therapies, ranging from steroid to surgeries that can be done under certain circumstances.
Characterization, formulation and evaluation of glibenclamide with ß-cyclodextrin inclusion complexes tablets Yandi Syukri; Farida Ulfa; Asih Lestari; Lelita Ayu Saputri; Rochmy Istikharah; Aris Perdana Kusuma
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss3.art3

Abstract

Background: Glibenclamide is an oral antidiabetic drug which is practically insoluble in water. Formation of ß-cyclodextrin inclusion complex was able to increase glibenclamide solubility. Objective: Aims of this study are to characterize, formulate and evaluate  inclusion complex tablets of glibenclamide to meet the requirements in Pharmacopeia.Methods: Inclusion complex was prepared in a 1: 1 and 1: 2 molar ratio  by spray drying method. Characterization were performed by using Fourier Transform Infrared (FTIR) spectroscopy and Scanning Electron Microscope (SEM). Further, it was formulated into tablets by direct compression technique using primojel and crospovidone as disintegrants.   Uniformity weight, hardness, friability, disintegration, and tablets were evaluated include dissolution. Dissolution studies of inclusion complex were performed by using United States Pharmacopeia (USP) II apparatus.  Drug concentration dissolution was determined with high pressure liquid chromatography (HPLC).Results: Result of FTIR and SEM provided evidence of  glibenclamide and ß-cyclodextrin complex formation after using spray drying methods. The tablet evaluation with primojel and crospovidone as disintegrant showed that increase concentration of disintegrant would increase disintegration time of the tablets. All of the formulas meet the requirements in the Pharmacopoeia.Conclusion: The inclusion complex of glibenclamide–ß cyclodextrin successfully used for enhancing the solubility of glibenclamide. The tablets meet the requirements in Pharmacopeia.
Comparison of meloxicam, tamsulosin and combination of both drugs with 16 Fr and 20 Fr catheter on trial without catheter successfulness in patients with benign prostatic hyperplasia Hasroni Fathurrahman; Doddy Moesbadianto Soebadi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art4

Abstract

Background: Acute urinary retention, is one of the main complications of Benign Prostatic Hyperplasia (BPH) in elderly patients. Trial Without Catheter (TWOC) is a way to evaluate whether a patient can urinate spontaneously after an episode of urinary retention. Objective: To prove that the combination of meloxicam 15 mg and tamsulosin 0.4 mg orally once daily for three weeks with 20 Fr catheter is more effective in the TWOC successfulness in BPH patients than meloxicam 15 mg or tamsulosin 0.4 mg alone with 16 Fr catheter. Methods: Patients BPH who had the first episode of urinary retention and fulfil the inclusion criteria were randomised. There were six treatment groups (n=6). The treatment group are meloxicam 15 mg + catheter 16 Fr (K1), combination of meloxicam 15 mg and tamsulosin 0.4 mg + catheter 16 Fr (K2), tamsulosin 0.4 mg + catheter 16 Fr (K3), meloxicam 15 mg + catheter 20 Fr (K4), combination of meloxicam 15 mg and tamsulosin 0.4 mg + catheter 20 Fr (K5), tamsulosin 0.4 mg + catheter 20 Fr (K6). For each group, drugs were given orally once daily for seven days. Efficacy of TWOC was assessed by the ability of spontaneous urinary after the first 24 hour post urethral catheter treatment, with Q-max result on uroflowmetry = 5 cc/sec and PVR = 100 cc. Result: All subjects from K1 and K4 experience a recurrent episode of urinary retention (100%), 83.3% in K3 and 66.7% in K6. In the combination group, K2 had 50% incidence of repeat urinary retention, while K5 had16.7%. From the whole group, a statistically significant difference with p <0.05 only can be found in K1 and K5 (p = 0.02).Conclusion: The combination of meloxicam 15 mg and tamsulosin 0.4 mg + 20 Fr catheter had a better effect in TWOC efficacy compared with the meloxicam 15 mg + catheter 16 Fr group.
Universal Health Coverage and a pledge to empowering persons with disabilities and ensuring inclusiveness and equality; how does this year’s theme benefit the deaf/dumb Juliet Mwale Musabula
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art1

Abstract

No Abstract
The comparison of transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) Yuliana Yakobus
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art2

Abstract

No Abstract
The effect of kersen's skin infusion (Muntingia calabura L.) on blood uric acid levels of the rats (Rattus novergicus) Asril Burhan; Usmar Usmar; Zulham Zulham; Ana Andarwiyati
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss3.art7

Abstract

Background: Uric Acid or Gout is the results of purine metabolism, i.e. the enzymatic reshuffle of body cells from dinucleotide or ribonucleotide acids. High uric acid levels can be settled in the central joints and mesenchymal tissues such as the kidney.Objective: To determine an effect of administering the Kersen's (Muntingia calabura L.) ripe skin infusion against uric acid levels in the rats which have been induced with caffeine.Methods: Eighteen rats was divided into six groups, i.e. three as a control group (negative, positive and normal) and three as a treatment group (0,5%, 1%, and 2% doses). The measurements of blood uric acid levels were performed before induction, after induction and after treatment on 9th, 12nd, and 15th days. Results: There was a reduction of the uric acid levels in the rats which administered by ripe Kersen's fruit skin infusion at 1% with 3,43 mg/dL and 2% with 3.32 mg/dL doses. However, this reduction is not equivalent to the effect of allopurinol control decreased at 2.9 mg/dL. Statistical analysis results with Complete Randomized Design (RAL) revealed that positive control group, infusion in 1% and 2% dose did not have a significant difference with normal controls, that means allopurinol and both doses test give an effect to return the uric acid to normal conditions.Conclusion: The ripe Kersen's (Muntingia Calabura) fruit skin infusion provides a reduction effect on blood uric acid levels in the rats (Rattus Novergicus) that have been induced by caffeine. Concentration of infusion that reduced effect of blood uric acid levels in the rats are at 1% ( 1 g/ 200 gBW) and 2% (2 g/200 gBW). However, the reduction is not equivalent to the positive control of Allopurinol.
Vaccines distribution system at primary healthcares in the special region of Yogyakarta Dian Medisa; Diesty Anita Nugraheni
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art8

Abstract

Background: Vaccine cold-chain distribution system must be monitored to guarantee the vaccine quality. Improper vaccine distribution system can cause damage and loss of efficacy. Therefore, the Indonesian government released some regulations to manage the vaccine cold-chain system, including the Good Distribution Practices for Pharmaceutical Products (Cara Distribusi Obat yang Baik/CDOB) in 2012 and Regulation of the Minister of Health Number 42 in 2013 (PMK 42/2013). Objective: The purpose of this study was to evaluate the implementation of the vaccine distribution system in primary healthcare (PHCs). Methods: A survey was conducted in 30 PHCs in the Special Region of Yogyakarta. Data were collected by observing the vaccine distribution system in PHCs using checklists developed based on CDOB 2012 and PMK 42/2013.Results: The study showed that the personnel in 24 PHCs (80%) checked the condition of the temperature monitoring device and Vaccine Vial Monitor (VVM) while receiving the vaccines. Furthermore, all PHCs (100%) had both cool packs and vaccine carriers, whereas those having cold packs were only 2 (7%). First expired - first out (FEFO) and first in - first out (FIFO) systems were implemented in 30 (100%) and 28 (93%) PHCs, respectively. Conclusion: The results indicated that most of the PHCs in Yogyakarta Special Region had implemented a good vaccine distribution system, yet they still need improvement especially in vaccine recording procedures.
Handsewn perineal rectosigmoidectomy (Altemeier) for complete full-thickness rectal prolapse: a case study Adeodatus Yuda Handaya; Aditya Rifqi Fauzi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jkki.vol9.iss3.art10

Abstract

Rectal prolapse is a condition in which the entire rectal wall layers protrude through the anal canal. This condition rarely occurs, and the management is still a challenge for both clinician and patient. Rectal prolapse management can be done transabdominally or transperineally. Full-thickness rectal prolapse in principle should have more attention to the rectum function and anal sphincter to prevent recurrence and erectile dysfunction. The Altemeier transperineal recto-sigmoid resection has become the most common for surgical management of rectal prolapse.We report four cases of rectal prolapse, two males and two females with chief complaints had lumps out from their anus. All patients displayed comorbidities. We performed the handsewn Altemeier procedure. All surgeries resulted in minimal intraoperative bleeding. Patients experienced neither incontinence, postoperative fistula, bleeding nor infection. One month after surgery, no patients experienced a recurrence of their complaints.Handsewn Perineal rectosigmoidectomy for the treatment of complete full-thickness rectal prolapse in patients who are having comorbidity can be considered to be an alternative treatment because the procedure is relatively more accessible, safe, and has fewer complications.

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