Ahmad Dahlan Medical Journal
Ahmad Dahlan Medical Journal is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Letters and commentaries of our published articles are welcome. Subjects suitable for publication include, but are not limited to the following fields of Allergy and immunology, Anesthesiology, Cancer and stem cells, Cardiovascular, Cell and molecular biology, Child health, Dermato-venereology, Geriatrics, Histopathology, Internal medicine, Neuro-psychiatric medicine, Ophthalmology, Oral medicine, Otorhynolaryngology, Physical medicine and rehabilitation, Physio-pharmacology, Pulmonology, Radiology, Surgery including orthopedic and urology, and Women’s health.
Articles
44 Documents
<![CDATA[Risk Factors of Kidney Failure Patients in Sardjito Hospital Yogyakarta ]]>
<![CDATA[Dewi Yuniasih]]>;
<![CDATA[Novi Wijayanti Sukirto]]>;
<![CDATA[Barkah Djaka Purwanto]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v1i2.3109
<![CDATA[The purpose of this study is to identify patients at high risk of kidney failure in order to plan treatment. Cross-sectional research method, carried out at the CAPD Outpatient Installation of Dr. Sardjito General Hospital, from October 2018 to November 2018. The results showed three major risk factors for kidney failure, namely hypertension (49.1%), diabetes (17.5%) %) and nephrotoxic (15.8%). The conclusion from the study is hypertension is the highest risk factor for kidney failure.]]>
<![CDATA[Characteristics of Kidney Failure Patients in Sardjito Hospital Yogyakarta ]]>
<![CDATA[Nuni Ihsana]]>;
<![CDATA[Dewi Yuniasih]]>;
<![CDATA[Barkah Purwanto]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v1i2.3127
<![CDATA[Chronic kidney disease (CKD) has become a serious public health problem. The aim of this study was to identify the characteristics of patients at high risk of developing kidney failure. The research subjects were analyzed as many as 57 subjects, showing that male sex (61.4%) suffered more from CKD than women (38.6%). The mean age was 37.84 ± 16.16 with a median length of  Continuous Ambulatory Peritoneal Dialysis (CAPD) of 36 months. Our study found 45.6% of the patients had an undergraduate degree, followed by 38.6% of the patients had a high school education. Further analysis is needed with more age groupings so that the characteristics of patients with kidney disease (CKD) can be known in detail from various elements of society. ]]>
<![CDATA[Swallowed dentures causing sigmoid perforation: a case report ]]>
<![CDATA[Mochammad Junaidy Heriyanto]]>;
<![CDATA[Triyoga Triyoga]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v1i2.3129
<![CDATA[We report the case of a 72-year-old man who accidentally swallowed his dental bridge. He did not realize his artificial teeth were swallowed. The patient was taken to the emergency room with complaints of abdominal pain. At the time of initial exploration, the patient was diagnosed with kidney colic. After a radiological examination, a foreign object was found. The patient undergoes laparotomy to evacuate a foreign body and find dentures. At the time of surgery, the operator observed the sigmoid perforation. ]]>
<![CDATA[Risk Factor for Erythropoietin Resistance in Hemodialysis Patient : Literature Review ]]>
<![CDATA[Rachma Greta Perdana Putri]]>;
<![CDATA[Amanatus Sholikhah]]>;
<![CDATA[Novi Sukirto]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v1i2.3131
<![CDATA[Anaemia become the complication of chronic kidney disease (CKD) which was caused by decreasing of erythropoietin. Erythropoietin stimulating agent (ESA) therapy is one of therapy to overcome the problem, but until 34% of patients have lack of response to ESA treatment. Anaemia in CKD related to the worsen of the diseases, quality of life, and mortality of patients. Decreasing of the response to erythropoietin need to be evaluated to correct anaemic condition. This review is aim to explain the risk factor for erythropoietin resistance. The literature for this review was collected through PUBMED and google scholar. Erythropoietin is glycoprotein secreted 90% by interstitial cells of kidney and 10% by liver cells. The functions of erythropoietin are stimulate the proliferation and cells differentiation in bone marrow, and enhance erythropoiesis. Renal damage can inhibit the secretion of erythropoietin. In patients with ESA treatment, risk factors for resistance are iron deficiency, inadequate haemodialysis, inflammation, hyperparathyroid, nutrition disturbance, antibody mediated Pure Red Cell Aplastic (PRCA). The risk factor can be influenced by genetic variation. Conclusion of this review, there are several factor that influence the response of erythropoietin in hemodialisa patients. Hence, study related anaemia in CKD need further study to optimalize the treatment.]]>
<![CDATA[The Protective Effect of Tropical Fruit Juice on Histopathological of Kidney Wistar Rats After Exposed Cigarette Smoke ]]>
<![CDATA[Novi Febrianti]]>;
<![CDATA[Haris Setiawan]]>;
<![CDATA[Rahmat Krestianto]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v1i2.3132
<![CDATA[Cigarette smoke is a toxic compound that can interfere with physiological effects and damage the organ systems in the body. The effects of free radicals arising from cigarette smoke can be neutralized by consuming antioxidant compounds. The research aims to look at the protective effects of mixed juice from tropical fruits that grow in Indonesia to the histopathological picture of the kidney of wistar rats exposed to cigarette smoke. There were 35 rats used and divided into 5 treatment groups consisting of K (without treatment), K- (cigarette smoke exposed), P1 (strawberry and guava juice mixed juice 3ml), P2 (strawberry and papaya mixed juice 3ml), P3 (P3 (strawberry and apple mixed juice 3ml). In P1, P2 and P3 before being given a mixture of fruit juice, rats were exposed to cigarette smoke first. The treatment was carried out for 40 days by oral gavage, then on the 41st day the rats were dissected and their kidney organs were taken for observation and histopathological preparations. Histopathology preparations were made by the paraffin method and Haematoxylin Eosin staining. The cell damage data is then analyzed by comparing the kidney cells from the control group with the treatment group and scoring damage followed by the percentage of kidney damage. Data were statistically tested using ANOVA followed by Post Hoc LSD. The results showed that mixed tropical fruit juice could protect kidney cell damage by decreasing the percentage of hydropic degeneration, necrosis and infiltration of inflammatory cells compared with negative controls (P <0.05). There is no significant difference between P1, P2 and P3 in reducing cell damage. The conclusion of the study is that all combinations of tropical fruit juice can protect cell damage caused by free radicals from exposure to cigarette smoke in wistar rats.]]>
<![CDATA[Anatomical Core Material of the Superior Extremity Musculosceletal System for Medical Student Learning ]]>
<![CDATA[Cholisa Fidduha]]>;
<![CDATA[Siti Munawaroh]]>;
<![CDATA[Nanang Wiyono]]>;
<![CDATA[Yunia Hastami]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 2 No. 1 (2021): May 2021 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v2i1.3330
<![CDATA[Background: Anatomy education is the essential basic science as a physician to run the clinical practice. The global development leads to the transformation of the medical curriculum which then results in the reduced time allotment for anatomic learning. In musculoskeletal system, superior extremity is one of the sections having the wide range of material coverage which cannot be learned in a short length of time. As a result, the students find it difficult to learn the material. A large number of anatomic material in superior extremity musculoskeletal system which need to be learnt in a limited time underlies the researcher to conduct this research.Methods: This research employed qualitative study using two-round Delphi method. The research subjects were 20 general physicians in Indonesia selected by purposive sampling. The initial questionnaire was arranged by the researcher based on 3 anatomic textbooks, 1 research on core anatomic material, 1 research on the anatomic component of clinical orthopedic, the substance recapitulation of national anatomy curriculum, and nomina anatomica. In the first Delphi round, the panel was asked to select the component which is important to be learned based on the clinical cases as well as to add whether the component has not been written yet by the researcher. In the second Delphi round, the panel ranked from 1-4. The consensus determined by the researcher is 35%.Results: In the first Delphi round, there is no topic added yet 53 components are removed. Thus, a number of component in the first round was decreased from 510 to 457 components. The second Delphi round obtains 26 core anatomic material out of 457 topics.Conclusion: General physician consensus is 26 from the core material out of the entire anatomic material in the superior extremity musculoskeletal system. There are also clinical reasons or correlation from the material of superior extremity muscukoskeletal system which are considered important by the panels. The results obtained from the panels who come from various regions to represent the general physician in Indonesia. Keywords: anatomy; core material; Delphi method; general physician consensus; musculoskeletal system,]]>
<![CDATA[Kaplan Meier's Analysis of Clinical Improvement Of Defecation Frequency In Pediatrics Patient With Diarrhea That Given Vitamin D As Adjuvant Therapy ]]>
<![CDATA[Nurcholid Umam Kurniawan]]>;
<![CDATA[Sutrimo Usali R]]>;
<![CDATA[Endang Darmawan]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 2 No. 1 (2021): May 2021 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v2i1.3460
<![CDATA[Diarrhea is the second leading cause of death in children under 5 years after pneumonia with a mortality prevalence of 8%. Diarrhea is a digestive disease with signs of bowel movements with a sudden consistency of loose stools 3 times or more in 24 hours, mostly caused by microorganisms (bacteria and viruses). The cure rate for diarrhea after receiving fluid replacement therapy and antibiotics for diarrhea caused by bacteria is quite high, but the mortality rate due to diarrhea is still high, therefore there needs to be an effort to add therapy to improve patient clinical outcomes. Vitamin D is known to play a role in the body's defense function, both in natural and adaptive immunity and plays a role in the body's defense in cases of infections, allergies, and autoimmunity. This study is an experimental double blind randomized clinical trial which was analyzed using Kaplan Meier. The research subjects were children aged 6 months to 18 years who were divided into two groups, namely the treatment group (n = 35) and the control group (n = 35). The treatment group received vitamin D and for the control group received a placebo. The data taken includes the results of the frequency of defecation of patients. The results of this study indicate that vitamin D is effective in accelerating the reduction in the frequency of defecation in children with diarrhea. Â Keywords: Diarrhea, Vitamin D, Defecation, Kaplan Meier]]>
<![CDATA[Neurological Manifestations of COVID-19 ]]>
<![CDATA[Andrianto Selohandono]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 2 No. 1 (2021): May 2021 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v2i1.3860
<![CDATA[COVID-19 disease has become a threat to global health. SARS-CoV-2 infection can cause damage to any other organs including the nervous system, which manifests as a neurological disorder. A number of neurological disorders have been reported in COVID-19 patients, including encephalopathy, stroke, myelitis, Guillain-Barre syndrome. The neurological manifestations in COVID-19 patients are varied and complex. A number of theories have been proposed to explain the pathomechanism behind the neurological diseases that develops in COVID-19 patients and are generally divided into direct and indirect effects of COVID-19. The direct routes involve invasion of the virus into the brain via olfactory, vascular pathways, or infiltration of infected immune cells; whereas indirect routes are the neurological consequences of systemic damage caused by viruses, such as inflammation, hypoxia, or hypercoagulable states. The neurological diseases experienced by COVID-19 patients can be caused by the pathophysiological process of the COVID-19 disease or other causes that coincide with viral infections.]]>
<![CDATA[Comparative Study on TGF-β Expression of Large Continues and Small Continues Stitch Technique Using Polyglecaprone 25 on Abdominal Skin Incision in Rattus Novergicus ]]>
<![CDATA[Dhyas Munandar AS]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 2 No. 1 (2021): May 2021 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v2i1.3914
<![CDATA[Ideal closing of the abdominal wound will provide strength and prevent infection. Abdominal wall closure method is an important aspect of effective incision closure, besides the choice of suture material. TGF-β generally involved in wound healing process. The suture technique is also important in wound healing process. This study aims to compare the large stitch technique with the small stitch technique for abdominal skin closure. Twenty rats were used in 4 groups. The small stitch group received small tissue bites of 5 mm from wound edge, and the large tissue group received large bites of 10 mm from wound edge. The incision of the skin was closed by running suture using polyglecarprone 25. Animal model were euthanized on the 4th and 7th day post incision. Tissue section were examined using immunohistochemistry method to measure TGF-β expression. The results were analyzed using t-test and the effect size. Rats in the small stitch group had higher TGF-β expression on day 4th and 7th than those in the large stitch group. TGF-β expressions in the small stitch group were 0,87 -fold greater on day 7th than day 4th and were 0,71 -fold greater in the large stitch group (p = 0,410). The significance analysis on day 4th with a result of 0,082 and day 7th with a result of 1.48, which means day 7th showed high effect (Cohen's d> 0.8) on wound healing than day 4th. In conclusion, polyglecaprone 25 use as a suture material on the day 7th showed a high effect in terms of TGF- β expression.]]>
<![CDATA[Albumin Description of Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients in Sardjito Hospital Yogyakarta ]]>
<![CDATA[Barkah Purwanto]]>;
<![CDATA[Dewi Yuniasih]]>;
<![CDATA[Metalia Puspitasari]]>
<![CDATA[ Ahmad Dahlan Medical Journal Vol. 2 No. 1 (2021): May 2021 ]]>
Publisher : <![CDATA[Universitas Ahmad Dahlan ]]>
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DOI: 10.12928/admj.v2i1.4086
<![CDATA[Albumin profile is an important sign of nutritional status as a quality-of life parameter, whereas hypoalbuminemia has been shown to be associated with a high mortality rate for patients with End Stage Renal Disease (ESRD) undergoing dialysis including CAPD. The study was conducted to determine serum albumin levels in patients with ESRD undergoing CAPD therapy. The study was conducted in a cross-sectional manner on ESRD patients who were still actively undergoing CAPD in the outpatient Installation of Dr. Sardjito Hospital Yogyakarta until November 2018. Subjects were examined for serum albumin levels. There were 57 research subjects with the category of albumin levels <3.5 g / dL as many as 19 (33.3%), between 3.5-4.0 g / dL as many as 27 (47.3%) and albumin levels> 4.0 g / dL of 11 (19.3%). There were no significant differences in all age groups, BMI and duration of CAPD. Albumin profile can be an independent parameter of quality of life and even a predictor of mortality in CAPD patients because it does not depend on age group, BMI and length of CAPD]]>
