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Istiqomah Rahmawati
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istiqomah.rahmawati@unej.ac.id
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+6285649555784
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jobc@unej.ac.id
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Jl. Kalimantan no 37 – Kampus tegal boto Jember Jawa Timur 68121, INDONESIA
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INDONESIA
Journal of Biobased Chemicals (JOBC)
Published by Universitas Jember
ISSN : 27463257     EISSN : 27462544     DOI : https://doi.org/10.19184/jobc.v2i1.116
Core Subject : Science, Engineering,
Chemical Engineering, Chemistry & Bioengineering Chemistry
The scopes of this journal include the following topics: 1. Components extract from bioresources 2. Chemical and physical processing of biomass 3. Biobased materials and composites 4. Biobased energy production 5. Catalyst technology for biomass conversion 6. Biological processing of bioresources, chemicals and waste 7. Treatment of biobased chemical waste 8. Application of the biobased chemical products to the target users 9. System analysis, management, and environmental protection of biobased chemical processing This journal does not consider the topics about organic chemicals from non-organism, crops and breeding, organism modification, metabolic engineering, bioresources and environmental management which do not relate to biobased chemical processing.
Arjuna Subject : Teknik Kimia (semua kategori) - Bioengineering
Articles 5 Documents
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Search results for , issue "Vol. 1 No. 1 (2020): Journal of Biobased Chemicals" : 5 Documents clear
Microwave Assisted-Extraction of Essential Oil from Fresh Basil (Ocium basilicium L.) Leaves Ditta Kharisma Yolanda Putri; Atiqa Rahmawati
Journal of Biobased Chemicals Vol. 1 No. 1 (2020): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (935.751 KB) | DOI: 10.19184/jobc.v1i1.105

Abstract

In this research, the extraction of essential oil from fresh basil leaves using solvent-free microwave extraction (SFME)and microwave hydrodistillation (MHD) method. Several parameters influence the extraction of basil oil using SFME method: microwave power, the ratio between the mass of raw material with a volume of distiller (F/D), material size, and length of extraction time. Besides, the components contained in basil oil and changes in oil gland conditions in basil leaves before and after being extracted were also evaluated. The optimum condition was obtained as follows: microwave power of 380 W, the ratio between the mass of raw material with a volume of distiller (F/D) of 0.1 g/mL, raw material size of intact (± 3 cm), with an extraction time of 60 min. Moreover, SFME has a shorter extraction time to produce yields than MHD methods. GC-MS analyzed the composition of basil oil, and there were 49 identified components. This study shows that SFME method more effective than the MHD method for extraction basil oil from fresh leaves based on time extraction and yield.
Natural Sources Screening for Antimicrobial Agents of Herbs, Spices, and Extract: A Semi-Qualitative Study Felix Arie Setiawan; Meta Fitri Rizkiana; Bekti Palupi; Istiqomah Rahmawati
Journal of Biobased Chemicals Vol. 1 No. 1 (2020): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (615.23 KB) | DOI: 10.19184/jobc.v1i1.107

Abstract

Indonesia has been recognized for its rich natural ingredients such as spices, herbs, and extracts for decades. Furthermore, these components also have been used as an herbal medicine for a long time ago. Meanwhile, the apparent capability comparison of several components on antimicrobial activity has not been updated yet. This study was conducting the comparison of antimicrobial activity for several materials such as noni (Morinda citrifolia), garlic (Allium sativum), celery (Apium graveolens), galangal (Alpinia galangal), ginger (Zingiber officinale), yellow turmeric (Curcuma longa), lime (Citrus aurantifolia), papaya (Carica papaya) leaf, betel (Piper betle) leaf, and cutcherry (Kaempferia galangal) using agar dilution method. Two types of bacteria are used for the test, namely gram-negative bacteria and gram-positive bacteria, with a total of seven bacteria. The media used were TSA (Trypticase Soy Agar) media for gram-negative bacteria and MRSA (Methicillin-Resistant Staphylococcus Aureus) media for gram-positive bacteria. This study had been conducted by using a fast screening method, which referred to a semi-qualitative method. Several components, such as noni, lime, and betel leaf, showed a significant result of antimicrobial activity. Otherwise, other compounds, surprisingly, could not suppress bacterial growth.
Biobutanol Production Using Fed-Batch High-Cell Density Extractive Fermentation Rizki Fitria Darmayanti; Yukihiro Tashiro; Kenji Sakai; Kenji Sonomoto
Journal of Biobased Chemicals Vol. 1 No. 1 (2020): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (782.366 KB) | DOI: 10.19184/jobc.v1i1.108

Abstract

Butanol, as a product with specific toxicity for its producer, is necessary to be maintained in low concentration during fermentation. In-situ integrated recovery using extensive volume extraction was used in high cell density fermentation in order to prevent the lag phase in the prime condition. Clostridium saccharoperbutylacetonicum N1-4 ATCC 13564 was employed to ferment glucose in extractive fermentation with oleyl alcohol as extractant. As the results of fed-batch cultures using high cell density with different extractant to broth volume ratios (Ve/Vb), 0.8 g/l butanol concentration in the broth was maintained with a ratio of 10, which was much lower than 4.4 g/l with the ratio of 0.5. Besides, the Ve/Vb ratio of 10 demonstrated 2.7-fold higher total butanol concentration (28 g/l) than that 11 g/l obtained with a Ve/Vb ratio of 0.5. These results indicated that larger Ve/Vb improved total butanol concentration by reducing butanol toxicity in broth.
Quantitative Structure-Activity Relationship Study of Ester-Based Ferulic Acid Derivatives Against Cervical Cancer Cell (HELA) Helda Wika Amini; Istiqomah Rahmawati; Rizki Fitria Darmayanti; Boy Arief Fachri
Journal of Biobased Chemicals Vol. 1 No. 1 (2020): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (641.554 KB) | DOI: 10.19184/jobc.v1i1.109

Abstract

Quantitative structure-activity relationship (QSAR) has been studied for ferulic acid derivatives to determine the QSAR model able to predict anticancer. As the subject of this research was a set of experimentally calculated IC50 value data of 6 ferulic acid derivatives against cervical cancer cells (HELA). QSAR analysis was based on multilinear regression calculation on fitting subset using log (1/IC50) as the dependent variable, and dipole moment, partition coefficient in the n-octanol/water, and atomic net charges of the aromatic carbons as independent variables. The values of the descriptors were obtained from semiempirical PM3 quantum mechanic calculation. The relationship between log (1/IC50) and the descriptors was described by the result in the QSAR model. The QSAR model for ferulic acid derivatives against HELA cell lineswas developed with the statistical parameters of R=0.998; R2=0.999; SE=0.00857; and F=394. The calculated log (1/IC50) using QSAR Hansch Model for ferulic acid derivatives have excellent agreement with experimental data of Log (1/IC50).
Optimization of Subcritical Water Assisted by Nitrogen Before Enzymatic Hydrolisis for Reducing Sugar Production Maktum Muharja; Nur Fadhilah; Rizki Fitria Darmayanti; Dwina Moentamaria; Arief Widjaja
Journal of Biobased Chemicals Vol. 1 No. 1 (2020): Journal of Biobased Chemicals
Publisher : Program Studi Teknik Kimia Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (892.156 KB) | DOI: 10.19184/jobc.v1i1.110

Abstract

The objective of this study is to optimize the three significant parameters of the subcritical water (SCW) process for sugarproduction from coconut husk by using response surface methodology (RSM). In this study, the effect of temperature, reaction time and solvent-feed (S/F) ratio was evaluated and discussed comprehensively. The results showed that the S/F ratio had the most significant effect on sugar yield. The optimal sugar yield was obtained at the highest S/F ratio of 23.4, the shortest time of 4.8 min, and the highest temperature of 183.6 oC of the SCW process. The characterization resultsconfirmed that the lignocellulose structure was changed remarkably then contribute to the efficient processes of enzymatichydrolysis. The parameters evaluation using RSM in this study suggests that SCW hydrolysis could be subjected to commercial purposes.

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