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INDONESIA
Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
Arjuna Subject : -
Articles 932 Documents
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The Role of Midazolam on Status Epilepticus: Systematic Review Azizah Amimathul Firdha; Vania Ayu Puspamaniar; Abduloh Machin
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 6 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i6.38806

Abstract

Background: Status epilepticus is a condition that results either in the failure of the mechanisms responsible for stopping seizures or in initiating mechanisms that cause seizures to be abnormally prolonged. Benzodiazepine is the first-line therapy for status epilepticus. The three usually used Benzodiazepines are Lorazepam, diazepam, and midazolam. Objective: This systematic review was undertaken to determine midazolam's role in managing patients with status epilepticus. Methods: A systematic search from PubMed, Science Direct, and Cochrane was conducted with predetermined keywords. Studies in randomized controlled trials assessing the impact of midazolam on epileptic status were included in the inclusion criteria. Articles are published in English, and the full text is accessible. The authors independently extracted data and assessed the risk of bias for each included study. Results: Of 6410 studies obtained from the search results, 13 studies were found that were relevant and matched the inclusion criteria. Benzodiazepines are the first line of SE therapy in an emergency. This group works by inhibiting GABA receptors and has a rapid effect in stopping seizures. Midazolam can be given intravenously, intramuscularly, or transmucosal (nasal, buccal, or rectal). Intravenous midazolam may be a good choice because of its short onset of action and, therefore, can effectively stop seizures. Conclusion: Effective and safe results have been seen with each Midazolam administration method. This suggests that Midazolam may be an excellent therapeutic option for SE. However, the type of Midazolam administration can be adjusted according to the guidelines and drug availability in each country. 
Emerging Frontiers in Cardiovascular Diagnostics: A State-of-the-Art Review Roy Novri Ramadhan; Dewi Ratna Sari; Muh Akram; Farhan Nurdiansyah
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 6 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i6.40838

Abstract

Background: The cardiovascular diagnostic landscape is rapidly evolving, with novel and advanced techniques and technologies continually emerging. Detection, monitoring, and management of cardiovascular diseases (CVDs) are quickly changing, which are leading mortality cause globally. Objective:This review aims to provide a comprehensive and up-to-date assessment of the current cardiovascular diagnostic modalities. It seeks to elucidate novel and promising technologies, address their advantages, limitations, and potential integration into clinical practice. Methods: This literature review discusses the recent cardiovascular diagnostics which were obtained from various sources such as PubMed, EMBASE, and Web of Science for articles published in the last decade. Results: The review identified vital emerging frontiers in cardiovascular diagnosis, including advancements in multi-modal imaging (such as PET-MRI), novel biomarkers, artificial intelligence applications, and the growing utility of wearable and remote monitoring technologies. Conclusion: Emerging techniques integration inroutine clinical practice requires careful consideration of their advantages and potential for improving patient outcomes. The review highlights the pressing need for continued research and guideline to ensure these innovations realize their full potential for the future of cardiovascular medicine.

Page 94 of 94 | Total Record : 932

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