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Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
Arjuna Subject : -
Articles 932 Documents
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RELATIONSHIP BETWEEN NEUTROPHIL LYMPHOCYTE RATIO AND CLINICAL SPECTRUM OF COVID-19 PATIENTS AT RSUD TUGUREJO SEMARANG Shafa Salina Amirah
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 3 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i3.37911

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is an infectious respiratory disease caused by infection novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 patients has different clinical spectrum, it depends on individual susceptibility and virus ability to infect. Supporting examination that can be used to screening, monitoring and evaluating COVID-19 patient is Neutrophil to Lymphocyte Ratio. Elevated NLR result indicates an imbalance immune response because neutrophilia and lymphopenia occurs.Objective: This study to determine whether there is a relationship between neutrophil lymphocyte ratios with clinical spectrum of COVID-19 patients at Tugurejo Hospital, Semarang.Methods: The research conducted at Tugurejo Hospital Semarang in November 2022. This study was an analytical observasional study with cross sectional design and used consequtive sampling. Total samples are 99 fit into the inclusion criteria carried out by data from medical records. Data analysis used Chi Square Test to assess whether there is a relationship between both variable. Results: The age of COVID-19 patients who hospitalized was 19 – 91 years old. Most of the clinical spectrum patients was moderate (49.5%) and neutrophil lymphocyte ratio result was ≥3.13 (high risk). On Chi Square test found the result of p-value is 0.045 (<0.05) between neutrophil lymphocyte ratio with the clinical spectrum of COVID-19 patients. Which meant that there was significant relationship between both variables.Conclusion: There is significant relationship between neutrophil lymphocyte ratio with clinical spectrum of COVID-19 patients at Tugurejo Hopsital Semarang.
An Overview of Chemotherapy Side Effects on Patients with Prostate Cancer, Bladder Cancer, and Testicular Cancer at Haji Adam Malik General Hospital Medan from 2020-2022 Felicia Jesslyn
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 3 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i3.37095

Abstract

Background: Chemotherapy is an alternative anticancer therapy. In general, side effects that will occur are hair loss, decreased appetite, weight loss, headache, fatigue, mouth ulcer, diarrhea, nausea and vomiting, constipation, nosebleed, skin rash, painful urination, muscle pain, and heartburn.Objective: To identify the most and least chemotherapy side effects in patients with prostate cancer, bladder cancer, and testicular cancer.Methods: The method used is descriptive quantitative with a total sampling technique. The study population was patients with prostate cancer, bladder cancer, and testicular cancer at Haji Adam Malik General Hospital Medan in 2020-2022, with a total of 38 people. Results: From the calculation of the frequency distribution, the sequence of side effects of prostate cancer chemotherapy was hair loss (94.1%), fatigue (88.2%), decreased appetite (76.5%), nausea and vomiting (70,6%), constipation (58.8%), muscle pain (47.1%), diarrhea (47.1%), weight loss (41.2%), skin rash (35.5%), painful urination (35.3%), headache (23.5%) %), mouth ulcer (23.5%), and heartburn (17.6%). Bladder cancer namely, fatigue (100%), decreased appetite (90.9%), nausea and vomiting (90.9%), muscle pain (63.6%), weight loss (63.6%), painful urination (54.5%), hair loss (45.4%), headache (45.4%), diarrhea (45.4%), constipation (45.4%), heartburn (36.4%), mouth ulcer (18.2%), and skin rash (18.2%). Testicular cancer namely, hair loss, decreased appetite, nausea and vomiting (100%), muscle pain (80%), weight loss (70%), fatigue (70%), heartburn (60%), mouth ulcer (50%), constipation (50%), headache (40%), skin rash (40%), painful urination (40%), and diarrhea (30%).Conclusion: Most to the least chemotherapy side effects are studied in patients with prostate cancer, bladder cancer, and testicular cancer. Keywords: Bladder Cancer, Chemotherapy, Prostate Cancer, Side Effects, Testicular Cancer
Giving Olive Oil to Diaper Rash in Infants Aged 6-12 Months in The Work Area Of The Nambo Health Center Suhartati Suhartati; Isra Wati; Fath Irtaniyah Rahman; La Ode Liaumin Azim
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 3 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i3.38562

Abstract

Background: Diaper rash is one of the most common skin diseases experienced by infants and toddlers with a high incidence and prevalence. Diaper rash occurs because the cause of diaper rash is fungus and bacteria. Treatment of diaper rash can be done in a non-pharmacological way, one of which is by using olive oil. Objective: The purpose of this study was to determine the effect of giving Olive Oil on diaper rash in infants aged 6-12 months in the working area of the Nambo Health Center. This type of research is a quasi-experimental design with one group pretest-posttest on 16 respondents through total sampling. Result: The results of this study indicate that before administration of olive oil, the most diaper rash in infants was moderate, namely 8 respondents (50%) while after administration of olive oil, diaper rash in infants recovered the most (no diaper rash). Namely 6 respondents (37.5%). Wilcoxon test shows the P value = 0.001 (≤ 0.05). Conclusion: So it can be concluded that there is an effect of giving olive oil to reduce the degree of baby diaper rash.
Association between Systole, Diastole, Sex, Age, Blood, and Urine Profile in Older Adults with Hypertension Desy Armalina; Neni Susilaningsih; Bambang Witjahjo; Ratna Damma Purnawati; Akhmad Ismail; Fanti Saktini
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 3 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i3.37060

Abstract

The main cardiovascular changes associated with aging included decreased heart rates, oxygen extraction, arterial stiffening, vasoconstriction, systolic blood pressure elevation, myocardial thickening, reduced diastolic filling rate, rhythmic rate changes, and action potential prolongation. Multifactorial risk can include the pathology of the diseased. This study aims to ascertain the relationship between systole, diastole, sex, age, blood, and urine profiles in an elderly with Hypertension. The logistic regression study found three significant associations between diastole systolic and leucocyte sedimentation with Hypertension. For the net study, various hormones are another pathological marker that can be included in hypertension screening  
The Comparison of Clinical Characteristics of Acute Decompensated Heart Failure Patients between JCARE-CARD Japan and dr. Kariadi Hospital Registry Mochamad Ali Sobirin; Kelly Kuswidi Yanto; Yan Herry; Sodiqur Rifqi; Hiroyuki Tsutsui
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 3 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i3.38665

Abstract

Background: _Heart failure (HF) is a major public health problem due to the high prevalence, poor prognosis, and huge costs contributed by frequent hospital admissions and prolonged care. Clinical characteristics of patients with HF might differ among different regions and races and low socioeconomic status was associated with increased incidence of heart failure. Indonesia dan Japan are both Asian countries with different race and socioeconomic status. No previous study has examined the difference of clinical characteristics between Indonesia dan Japanese HF patients.Objective: To investigate HF patients demographic and clinical characteristics in Indonesia and compare with Japanese  registryMethods: In this retrospective observational study, patients presenting with acute decompensated heart failure (ADHF) at dr. Kariadi Hospital (RSDK) were consecutively recruited during 2014-2015 hospitalization period. Baseline data including demographic, clinical characteristics, laboratory data on admission, medication use before hospitalization,  and length of stay during hospitalization were collected from medical record using the form of the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). The descriptive analysis was performed to compare those HF characteristics.Results: A total of 246 ADHF patients in RSDK registry were included with average age of responden was 56.4 years-old and 57.3% were male. Etiology was predominantly ischemic heart disease (IHD) in 60.6%, average left ventricular ejection fraction 40.1% and length of hospital stay was 8.8 days. Compared to Japanese registry, the characteristics of clinical status and laboratory data on admission were almost similar between studies except for higher prevalence of ischemic heart disease, renal dysfunction and dyslipidemia but lower prior stroke in RSDK study. The average length of stay at hospital was longer in Japanese registry (8.8 days vs. 33.9 days).Conclusion: Ischaemic heart disease and renal dysfunction more prevalent in RSDK registry, but prior stroke and length of stay at hospital higher in Japanese registry of hospitalized ADHF patients.
Differences of Schirmer’s Test Result In Patients With Controlled And Uncontrolled Diabetes Mellitus Atika Hazmi; Riski Prihatningtias; Hesti Triwahyu Hutami; Maharani Cahyono
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 4 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i4.37733

Abstract

Background: Diabetes Mellitus (DM) is a metabolic disease whose prevalence continues to increase every year. Peripheral neuropathy as a microvascular complication of DM can cause dry eye syndrome. HbA1c levels can determine controlled or uncontrolled DM.Objective: To determine the differences of the Schirmer’s test result for patients with controlled and uncontrolled diabetes mellitus.Methods: This study was an analytic observational study with cross sectional design. The study subjects were 44 diabetes mellitus patients consisting of 22 patients with controlled DM and 22 patients with uncontrolled DM who were selected based on inclusion and exclusion criteria, using consecutive sampling method. Data were collected from primary data that consists of name, age, gender, duration of DM, medical history, Hb, MCV, HbA1c and the Schirmer’s test result. The data were analyzed using non parametric Mann Whitney test and p < 0.05 was taken as significance.Results: The Schirmer’s test result < 10 mm which indicated the presence of dry eye syndrome was mostly found in female (71.4%), age > 45 years (85.7%), duration of DM > 10 years (78,6%), and patients with uncontrolled DM. The non parametric Mann Whitney test showed that there was a significant difference in the Schirmer’s test result (p < 0,05) between patients with controlled and uncontrolled DM.Conclusion: The Schirmer’s test result in patients with controlled DM was higher than patients with uncontrolled DM.
CASE REPORT : A 30-YEAR-OLD FEMALE IN THIRD TRIMESTER PREGNANCY WITH VARICELLA Ahmad Fikri Pulungan; Wizar Putri Mellaratna
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 4 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i4.37655

Abstract

Background Varicella (chickenpox) is a common childhood disease, but if it develops during pregnancy, it can have serious and undesirable consequences, including congenital varicella syndrome, maternal VZV pneumonia, and neonatal varicella infection; this can lead to feto-maternal morbidity and mortality. Antiviral therapy and appropriate supportive care improve maternal and neonatal outcomes. This case report provides an overview of varicella-zoster virus infection during pregnancy.Case Presentation: We present a case, a 30-year-old woman in the third trimester of pregnancy came to the emergency department of Cut Meutia Hospital with complaint of vesicle with that was very itchy on the face and all over the body. The patient also complained fever, had no appetite, itching in the throat and coughing up phlegm.Conclusion: The patient was diagnosed with varicella caused by varicella zoster virus and treated with acyclovir.
THE RELATIONSHIP OF PERSONAL HYGIENE ON THE SEVERITY OF ACNE VULGARIS IN MEDICAL STUDENTS WAHID HASYIM UNIVERSITY Ariska Oktaviani; Fatinah Shahab
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 4 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i4.38034

Abstract

Background: Acne vulgaris generally occurs in men and women, adolescents, and young adults. it is caused by propionibacterium acnes, which is an anaerobic bacteria that is gram-positive. There are other factors that cause acne such as hormones, oily, and dirty skin from dust and air pollution. The incidence of acne vulgaris can be influenced by the level of poor personal hygiene. Objective: This study aims to determine the relationship between personal hygiene and the severity of acne vulgaris among students of Faculty Medicine, Wahid Hasyim University, Semarang. Methods: The study was conducted on 45 students in the Faculty of Medicine, Wahid Hasyim University, Semarang using a cross-sectional method with a simple random sampling technique. The instruments used in this study were questionnaires. Results: There was a significant relationship between personal hygiene and the degree of severity of acne vulgaris. The chi-square statistical test obtained a p-value of 0.015 (p-value< 0.05). Conclusion: Students should always maintain and improve personal hygiene by bathing regularly 2 times a day, changing clothes 2 times a day, washing hands after activities, using personal towels and drying in the sun after use, and always maintaining the cleanliness of the bed by changing bed sheets regularly and periodically. 
Case Report: Enterocutanic Fistle Syafruddin Syafruddin; Della Vega Nisha Ayuna; M Fathul Arif
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 4 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i4.37649

Abstract

Fistula is an abnormal connection between a channel with another channel (internal fistula), or a channel with the outside through the skin (externa fistula). A male, 48 years old, came to the RSUCM Hospital with complaints of discharge from the wound after a hernia operation on the left hip since 1 month at the SMRS. The liquid comes out in small increments, spontaneously, in lumps the size of corn kernels, blackish brown and sometimes greenish yellow, and smells bad. Surgical scars are often inflamed since 6 months after hernia surgery and have often been constipated since the operation. History of hypertension and diabetes mellitus since 4 years ago, not in control and not taking medication regularly. On physical examination, vital signs revealed hypertension. On physical examination, the status of the left iliac a/rillois was seen, an open wound measuring 1x1.5 cm, smelly discharge (+), felt warm, edema (+), NT (+). On complete blood laboratory examination, found within normal limits. At the time of colonoscopy. 
Association Between Stunting and Anemia Among Toddlers: Stratified by Characteristic of Family and Immunization Status in Mlonggo District, Jepara Regency Arwinda Nugraheni; Muflihatul Muniroh; Yora Nindita; Firdaus Wahyudi; Bambang Hariyana
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 4 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i4.38561

Abstract

Background: The risk of anemia in stunted toddlers is higher than in normal toddlers. There is limited research on anemia in children under 3 years old in the community and there is a need for supporting research to prove the possibility of controlling stunting and anemia together. Previous studies have shown that family characteristics and immunization status are associated with the stunting and anemia.Objective: This study aims to analyze the association between anemia and stunting in toddlers that are stratified by characteristics of family and Immunization status.Methods: This study used a cross-sectional design study and was conducted on September-October 2020 in the Mlonggo District, Jepara Regency. One hundred two respondents were selected by cluster random sampling technique. The questionnaire was applied to collect the data on stunting, anemia, immunization status, age, mother's occupation and education status, SCREEM score, and APGAR score. This study used the Chi-Square statistic test.Results: The anemia status was measured by the Hb meter. The characteristics of stunting status (stunting = 17.7%, no stunting= 82.3%), anemia status (Yes = 63.7%, No = 36.3%). The association between stunting and anemia was stratified by the child age (6-23 months) (PR=1.667; 95%; CI=1.103-2.519; P=0.123), employed mother (PR=1.593; 95%CI=1.265-2.005; P=0.154), incomplete and inappropriate immunization status (PR=1.636; 95%CI= 1.132-2.366; P=0.133) and highly internal family function; (PR=1.512; 95% CI=1.270-1.799; P=0.029).Conclusion: There was an association between stunting and anemia in toddlers from child age of 6-23 months, employed mother, incomplete and inappropriate immunization, and highly family function groups.

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