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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 471 Documents
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Prediktor Komplikasi Dengue Shock Syndrome (DSS) pada Pasien Pediatri dengan Dengue Hemorrhagic Fever (DHF) Ahmad Arkan Ichsan; Khairun Nisa Berawi; Neema Putri Prameswari; Ratu Nirmala Wahyunindita
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.42

Abstract

Dengue Hemorrhagic Fever (DHF) are tropical infectious diseases prevalent in tropical, subtropical and temperate climate countries, complications of DHF that leads to Dengue Shock Syndrome (DSS) may have drastic implications towards the mortality of pediatric patients. Ongoing assessment is still proceeding on Risk factors for the patient’s progression to DSS and there are several predictors utilized on patient follow-up that may indicate high risk of clinical symptom progression to DSS. Several predictors are identified to be the female gender, age between 6-10 years, hepatomegaly, late clinical management, heavy plasma leakage, obesity, spontaneous bleeding, gastrointestinal bleeding and presentations of ascites and pleural effusion. Several lab examinations include leucopenia, prolonged aPTT, low platelet count, thrombocytopenia, hematocrit of ≥ 40, low lipid profile, hypoalbuminemia, hypoproteinemia. There are also other predictors identified such as high Troponin T levels, NS1Ag expression, NK and NKT gene expression, elevated Vitamin D levels, Fatty acid levels. high sTM levels, elevated Chymase enzyme serum levels and elevated lactate serum levels. The usage of machine learning and algorithms may also prove useful in predicting DSS complications through pattern identification. There is a wide array of current and new methodologies to predict DHF progression to DSS, and further review analysis may be needed to determine concrete indicators for predicting DHF progression to DSS. Newer methods may prove useful, and would need further testing to ensure its capabilities on predicting DSS.
Pengaruh Pemberian Ekstrak Etanol Rimpang Lengkuas (Alpinia galanga) terhadap Gambaran Histopatologi Testis Mencit (Mus musculus L.) jantan yang Diinduksi Monosodium Glutamat Annisa Shafira Pramono; Muhartono; Rizki Hanriko; Eca Cania
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.43

Abstract

Monosodium Glutamate (MSG) may form free radicals that cause damages to the organs of the body, one of which is the male reproductive organs, i.e. testes. Galangal rhizome is one of the natural ingredients with antioxidant content that can neutralize free radicals. The purpose of this research was to determine the effect of ethanol extract of galangal rhizome on testicular histopathology of MSG-induced male mice. The design of this research was experimental research with 5 treatment groups, each group consisted of 5 mice (Mus musculus L.) DDY strain. Group K (-) was not treated; k (+) was provided with 4 mg/ grBB MSG; P1 was provided with 4 mg/ grBB MSG + 14 mg/ 20 grBB ethanol extract of galangal rhizome; P2 was provided with 4 mg/ grBB MSG + 28 mg/ 20 grBB ethanol extract of galangal rhizome; P3 was provided with 4 mg/ grBB MSG + 56 mg/ 20 grBB ethanol extract of galangal rhizome. Assessment used Johnsen score in group K(-) was 48,4, K(+) was 47,4, P1 was 47,4, P2 was 47,4, and P3 was 48. Kruskal-Wallis test result was p=0,085 (p>0,05). The conclusion was that ethanol extract of galangal rhizome did not effect significantly (p>0,05) on the testicular histopathology of monosodium glutamate-induced mice.
Uveitis Intermediet dengan Glaukoma Sekunder Okuli Sinistra Desty Marini; Rani Himayani; Helmi Ismunandar
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.44

Abstract

Uveitis is inflammation that occurs in the uvea tract. Intermediate uveitis is inflammation of the vitreous body, the retinal blood vessels. The most caused of secondary glaucoma is inflammation of the eye. Glaucoma is one thah cause increases intraocular pressure causing optic nerve damage and interference with the visual loss. Case description, female patients within 32 years came with the main complaint that the left eye visual loss since one week ago. Complaints the patients are headache, nausea, vomiting at three times, and glare when the eyes exposed to sunlight. Headache especially in the left eyelid. Wearing glasses (+), red eye history (+). Ophthalmological examination found on right eye visus 2/60, left eye visus 1/300, right eye intraocular pressure 10mmHg and left eye 58mmHg. Examination of the anterior segment of the right eye was within normal, anterior segment of the left eye was palpebra pseudoptosis, fornix and bulbi, tarsal conjunctiva injection, ciliary injection, corneal edema, precipitous keratic, deep anterior chamber, hypopion of zero point five millimeters, pupil dilatation, iris kripta, pupillary reflexes, the lens, vitreous not visible because the media was heavy. The mechanism of IOP increase in open-angle glaucoma caused by uveitis were hypersecretion, blockage of the trabecular meshwork, inflammation of the trabecular meshwork, trabeculum and endothelium damage, and glaucoma caused long-term use corticosteroids. Treatment used was carbonic anhydrase inhibitors, beta adrenergic inhibitors, topical and systemic anti-inflammatory drugs.
Glaukoma yang Diinduksi Steroid Oculi Dextra Et Sinistra Rahmanindya Defiyandini Puteri; M. Yusran
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.45

Abstract

Steroids are a group of anti-inflammatory drugs, commonly used to treat ocular and systemic conditions. Unmonitored use of steroids especially in eye drop formulations is common in situations when it is easily available over-the-counter, resulting in undesirable side effects. Ms. L, 17 years old, both eyes could not see without red eyes since 8 months ago. Initially the patient feels increasingly blurry until finally unable to see. Before experiencing this the patient had a history of using eye drops cointaing steroid for almost 1 year because her eyes were often red. Ophthalmological examination obtained vision oculus dextra: ½/60, vision oculus sinistra 1/300, no injection of right and left conjunctiva, deep right and left front chambers, pupillary light reflexes decreased in both eyes, right and left clear lens, oculi tension N+1 per palpation, narrow vision field, and in fundoscopic examination found cupping of the optic disc with cup disc ratio of 0.9, nasalisation of blood vessels and lamina cribosa were clearly seen in both eyes. Therapy given to this patient was Timolol maleate 0,5% eye drop 1 drop /12 hours and Latanoprost 0.005% eye drop 1 drop /24 hours. Patients were also planned for trabeculectomy surgery.
Pengaruh Suplementasi Zinc dan Vitamin C terhadap Pasien Malaria yang Anemia Januar Ishak Hutasoit; Intanri Kurniati
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.46

Abstract

Malaria is one of disease that has a high incidence in Indonesia. This disease is caused by the Plasmodium parasite which can attack and damage red blood cells. Things that can occur in patients infected with Plasmodium are anemia. Anemia is a condition where there is a decrease in hemoglobin and erythrocyte levels in the blood. Anemia that occurs in malaria generally is normocytic, normochromic, and hemolytic anemia. Hemolytic anemia occurs because of the process of hemolysis, which is an increase in destruction of erythrocytes or premature breakdown of erythrocytes. Vitamin C and Zinc are known as minerals that can help iron activity. Iron is included in the formation of hemoglobin, but in malaria patients giving iron tablets can worsen the patient's condition, therefore it is done giving vitamin C and Zinc in preventing and helping to overcome anemia in malaria patients.
Penatalaksanaan Holistik Dermatitis Kontak Iritan Pada Pekerja Bangunan Muhammad Ega Alfarizi; Azelia Nusadewiarti
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.47

Abstract

Irritant contact dermatitis is a skin disorder that can be found in about 85-98% of all skin diseases caused by work in Indonesia. Symptoms of burning, stinging and pain relief after exposure to cement and wood dust which are irritating. Pharmacologic treatment and preventive measures using personal protective equipment (PPE) are important in the management of occupational dermatitis. Study analysis in this case report identified risk factors and clinical problems in patients by implementing a holistic and comprehensive family doctor approach and its management with holistic and comprehensive, patient centered, family focused, and community oriented by conducting health promotion intervention methods, applying healthy behaviors with precaution adoption process model and treatment of irritant contact dermatitis based on evidence based medicine. Primary data obtained through history taking, physical examination and home visits to complete family data, psychosocial and environmental data. Assessment is based on a holistic diagnosis from the beginning, process, and end of study quantitatively and qualitatively. Patients have aspects of internal risk lack of knowledge about irritan contact dermatitis, curative treatment patterns, behavior that does not use personal protective equipment when working. The external risk aspect for patients is the lack of knowledge and family support in treatment. Furthermore, holistic management of patients and families is carried out through health promotion intervention methods in the form of information about irritan contact dermatitis such as educating the precipitating factors and emphasizing the importance of using personal protective equipment (PPE) when working. In the evaluation it was found that the patient’s complaints were reduced, sufficient knowledge of the disease, changes in patient behavior, and application of personal protective equipment (PPE) at work. Holistic management can improve knowledge, attitudes, and behavior in patients.
Hubungan Tahap Pengobatan dengan Kualitas Hidup Pasien Multidrug-resistant Tuberculosis di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Muhammad Rifki Pratama; Asep Sukohar; Khairun Nisa Berawi
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.48

Abstract

Tuberculosis (TB) is the number one infectious disease in the world as the most frequent cause of death. TB infects 10 million people each year and becomes the 10th highest cause of death in the world.Multidrug-resistant Tuberculosis (MDR-TB) is a type of TB germ resistance against at least two first-line anti-tuberculosis (OAT) drugs. MDR-TB treatment certainly takes longer than 18 months. This very long treatment can affect the quality of life of MDR-TB patients. This study is to determine the correlation between the treatment phases with the quality of life of patients with Multidrug-resistant Tuberculosis in Dr. H. Abdul Moeloek Hospital Lampung Province. This study used 68 respondents who had been diagnosed with MDR-TB by pulmonary specialists. Primary data was taken using SF-36 questionnaire to measure the quality of life of MDR-TB patients, then secondary data based on the treatment phases using the medical record of the patient who had filled out the questionnaire. The data is processed and analyzed by the program in the computer. Data were tested by chi-square test and the results were obtained from 30 respondents in the initial treatment phases, 22 people (73.3%) quality of life was poor and 8 people had good quality of life (26.7%), while from 38 respondents at the continued treatment phases, as many as 12 people (31.6%) quality of life is bad and 26 people have good quality of life (68.4%). The result of bivariate analysis showed the variable had a correlation with p-value=0,001. There is a correlation between the treatment phases with the quality of life of patients with Multidrug-resistant Tuberculosis in RSUD Dr. H. Abdul Moeloek.
Hubungan Konsumsi Suplemen Kalsium yang Kurang Selama Kehamilan sebagai Risiko Kejadian Preeklampsia di Rumah Sakit Umum Daerah (RSUD) Kota Agung Kabupaten Tanggamus Rendika Oktavia Widiastuti; Dyah Wulan Sumekar; Ratna Dewi PS; Rodiani
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.49

Abstract

Preeclampsia is one form of hypertension in pregnancy. The proportion of hypertension in pregnancy as the leading cause of maternal mortality is increased compared with bleeding and infection. There are potential benefits from the consumption of calcium supplements during pregnancy that decrease preeclampsia. The Purpose of this study was to determine the risk of consuming fewer calcium supplement during pregnancy to the incidence of preeclampsia at RSUD Kota Agung Kabupaten Tanggamus. The design of this study is case-control. The case population was pregnant women with preeclampsia and the control population was pregnant women without preeclampsia. The sample of case consists 46 respondents and sample of control consists 46 respondents. Incidence of preeclampsia data was obtained from the KIA book, while consumption of calcium supplement from the questionnaire. Bivariate analysis using Chi-square. In pregnant women with preeclampsia more who consuming less calcium (65.2%) than the control group (34.8%). Based on bivariate analysis, p = 0.004 and OR 3.875 (95% CI: 1.632 – 9.203). Consumption of fewer calcium supplements during pregnancy may increase the risk of preeclampsia by 3.8 times when compared with those consuming enough calcium supplements during pregnancy.
Osteochondritis Dissecans Helmi Ismunandar
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.50

Abstract

Osteochodritis dissecans (OCD) is a focal change in the subcondral bone. This alteration results in either partial or complete osteochondral fragmentation. OCD usually suffered by athletes (children, adolescents, or adults). Osteochondritis dissecans is source of pain and knee dysfunction during adolescent growth. It need to detected early to avoid secondary osteoarthritis. It most commonly occurs in the knee (75%), elbows (5%), and ankles (4%). Total incidence of OCD in the distal femur is 6,09 per 100.000 people per year. Male’s incidence (8,82-10 per 100.000) is higher than women’s (3,32- 4,04 per 100.000). Juvenile type knee OCD usually occurs at age 11,3-13,4 years. The average age on adult OCD is 17- 36 years. The pathogenesis of OCD is still not fully understood. Impact injuries can cause edema or bleeding in the subarticular bone. Local ischemic arises due to capillaries squeezing or thrombus formation. In certain circumstances, osteochondral fractures or fragmentation can occur. OCD can be treated both nonoperatively and operatively.
Penatalaksanaan Gout Arthritis dan Hipertensi Grade I pada Wanita Lansia Obesitas melalui Pendekatan Dokter Keluarga Intan Hardianti; Diana Mayasari
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.51

Abstract

Gout or commonly known as gout arthritis is a disease caused by the accumulation of monosodium uric crystals in the body. Gout is estimated to occur in 840 people out of 100,000 people. Hypertension is a state of systolic blood pressure of more than 140 mmHg and diastolic of more than 90 mmHg. Based on blood pressure measurements, the prevalence of hypertension in the population aged 18 years and above in 2013 in Indonesia is 25.8%. The use of evidence-based medicine of family doctor services is done by identifying risk factors, identifying clinical problems, and patient management based on the framework of solving patient problems through a patient-centered and family approach. This is a case report study. Assessment is done based on initial diagnosis, process, and end of study qualitative and quantitatively. The patient was a 63-year-old female, a housewife. Patients were diagnosed with Class I Gout Arthritis and Hypertension, and Class II Obesity. Patients and families have less knowledge about the disease and unhealthy lifestyles. This is a risk factor for disease complications in patients. Gout Arthritis and hypertension with less knowledge about risk factors, adherence to routine drug use, and compliance with periodic control to the doctor can cause acute and advanced complications. Complications can be prevented by the family doctor approach.

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