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All Journal Jurnal Sains dan Pendidikan Fisika Kodifikasia: Jurnal Penelitian Islam JFIOnline Jurnal Ilmiah Kesehatan Diagnosis Pharmaceutical Sciences and Research (PSR)
Abdul Munim
Fakultas Farmasi, Universitas Indonesia
Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Instant Powder Formulation for Anti Anemia and Optimization Exctraction Condition of Moringa pterygosperma Gaertn Leaves Using MAE Anggraeni, Yosita; Jufri, Mahdi Jufri; Munim, Abdul
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 7, No 3 (2015)
Publisher : Indonesian Research Gateway

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Abstract

Iron supplement containing ferrous sulfate is commonly used for anaemia. Unfortunately, it has bad taste, can cause nausea, and made adverse effects if taken in large doses for long periods. It is necessary to ????ind an alternative source of raw materials, including those from plants. Moringa pterigospera Gaertn leaves was selected because it contains iron and other nutritions. The purpose of this work was to make instant powder formula for anti anaemia using Moringa leaves extract as an alternative for ferous suphate iron suplementation. The extraction was performed by Microwave Assisted Extraction method. Optimization of extraction condition was performed by creating some variations in solvent composition (0- 70% ethanol), microwave power (450 to 900 watts) and extraction time (3 to10 min). Iron content was determined by Atomic Absorption Spectrophotometer at wave length of 248 nm. Instant powder formula was made in 3 concentrations of sodium CMC as suspending agent. Results of the study showed that the most optimal extraction condition which resulted the highest iron content (2.4 mg/g extracts) achieved with 900 watts microwave power, 10 min extraction time and aqua demineralisata. According to 30 panelists of hedonic test, formula which used 5% w/w of sodium CMC got the highest scores. Its powder form had 2.31% of loss on drying and 7.74 g/sec of ????low rate for powder form and pH of 5.78, viscosity of 15.98 cps for reconstituted form.
Instant Powder Formulation for Anti Anemia and Optimization Exctraction Condition of Moringa pterygosperma Gaertn Leaves Using MAE Anggraeni, Yosita; Jufri, Mahdi Jufri; Munim, Abdul
Jurnal Farmasi Indonesia Vol 7, No 3 (2015)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.116 KB) | DOI: 10.35617/jfi.v7i3.306

Abstract

Iron supplement containing ferrous sulfate is commonly used for anaemia. Unfortunately, it has bad taste, can cause nausea, and made adverse effects if taken in large doses for long periods. It is necessary to 􏰁ind an alternative source of raw materials, including those from plants. Moringa pterigospera Gaertn leaves was selected because it contains iron and other nutritions. The purpose of this work was to make instant powder formula for anti anaemia using Moringa leaves extract as an alternative for ferous suphate iron suplementation. The extraction was performed by Microwave Assisted Extraction method. Optimization of extraction condition was performed by creating some variations in solvent composition (0- 70% ethanol), microwave power (450 to 900 watts) and extraction time (3 to10 min). Iron content was determined by Atomic Absorption Spectrophotometer at wave length of 248 nm. Instant powder formula was made in 3 concentrations of sodium CMC as suspending agent. Results of the study showed that the most optimal extraction condition which resulted the highest iron content (2.4 mg/g extracts) achieved with 900 watts microwave power, 10 min extraction time and aqua demineralisata. According to 30 panelists of hedonic test, formula which used 5% w/w of sodium CMC got the highest scores. Its powder form had 2.31% of loss on drying and 7.74 g/sec of 􏰁low rate for powder form and pH of 5.78, viscosity of 15.98 cps for reconstituted form.
Co-Authors . Andriansjah . Azizahwati Alwi, Muh. Khidri Aminuddin Syam Andita Mandasari Andita Mandasari, Andita Anggraeni, Yosita Anggraeni, Yosita Ayu Andriani, Ayu Ayu Fimani Azizahwati Azizahwati, Azizahwati Dini Hariria, Dini Effionora Anwar Endang Hanani Endang Hanani Fadlina Chany Saputri Hayun Hayun, Hayun Heni Susilowati Hidayati, Niswatul Joshita Djajadisastra, Joshita Lukman Santoso Mahdi Jufri Maria Tuntun Octaviarini Hidayah, Octaviarini Raditya Iswandana Rahmadiah, Rahmadiah Retnosari Andrajati Santi Purna Sari Santi Purna Sari Sappewali, Sappewali Sri Wulandah Fitriani, Sri Wulandah Ulfah Aunillah, Ulfah Wahyuni, Ayusari Yohanna Aristanti