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All Journal Jurnal Arsitektur DASENG Dentika Dental Journal SPASIAL Jurnal Elementer (Elektro dan Mesin Terapan) International Journal of Nursing and Health Services (IJNHS) Kemadha

Suryono

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Author-ID : 1157531

Arts Civil Engineering, Building, Construction & Architecture Dentistry Electrical & Electronics Engineering Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Mechanical Engineering Nursing Public Health Social Sciences

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EFFECT AMOUNT OF CIGARETTE SMOKING ON GINGIVAL EPITHELIUM THICKNESS : EFEK JUMLAH ROKOK SIGARET TERHADAP KETEBALAN EPITHEL GINGIVAL Asam Khalifa Mohammed; Suryono; Siti Sunarintyas
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Smoking is one of the most important risk factors for oral diseases. Tobacco smoking produces more than 4000 chemical materials. Gingival protects underlying tissue to oral environment. Cells of gingival epithelium are metabolic actively, and can be reacted to internal and external stimuli. The thickness of oral mucosa epithelium is related with the amount of cell or proliferation activity. This study aimed to investigate effect amount of cigarette smoking on thickness of gingival epithelium. This study was animal experimental laboratory study. This study used 40 males Rattus Norvegicus strain Spraque Dawley, and were divided into 4 groups. They were control, mild, moderate and severe smoker groups. The animal models were exposed 2 grams by pump and were euthanized with ketamine in the 7th day. Measurement of gingival epithelium thickness used hematoxylin eosin that was measured from basale to granular layer and 3 sites (in µm). Data were analyzed by one way anova. The results of this research showed that there was an increasing thickness of gingival epithelium of animal models. The highest of gingival epithelium thickness was in severe smoker groups. In conclusion, cigarette smoking influenced on gingival epithelium thickness.

C-TELOPEPTIDE PYRIDINOLINE LEVEL IN GINGIVAL CREVICULAR FLUID AS INDICATOR OF ALVEOLAR BONE RESORPTION: KADAR C- TELOPEPTIDA PIRIDINOLIN PADA CAIRAN KREVIKULAR GINGIVA SEBAGAI INDIKATOR ADANYA RESORBSI TULANG ALVEOLAR Agustin Wulan; Widjijono; Suryono
Dentika: Dental Journal Vol. 16 No. 1 (2011): Dentika Dental Journal
Publisher : TALENTA

Periodontal disease is an inflammation and degeneration of chronical dental support tissue, accumulative, and progressive that caused tooth loss. Periodontal disease is caused by bacteria that has an ability to activate host response to produce pro-inflammatory mediator. Pro-inflammatory mediator causes collagen fibers degradation or destruction in periodontal tissue. Collagen cross- link of peri odontal tissue would be broken down and released into serum, and then excreted through urine. Collagen cross-link is called pyridinium cross-link, such as pyridinoline, deoxypyridinoline, N-telopeptide, and C- telopeptide (ICTP). This study was to investiga te the level in gingival crevicular fluid as an indicator of alveolar bone resorption. This study used 24 subjects with periodontal disease and 6 healthy subjects. Dividing of periodontal disease was based on periodontal index and every subject had minimum 20 teeth in mouth. Gingival crevicular fluid was taken at mesial site of maxillary posterior tooth by paperpoint and was measured by ELISA technique. The result showedthat the lowest level of ICTP was in control group, and the highest level was in grade 3 periodontitis group. The level of ICTP increased followed by periodontal disease progression. The result of Kruskal- Wallis-H and Mann-Whitney-U test showed th at was significant difference in ICTP between subject with and without periodontitis (p<0.05). It can be concluded that ICTP level in gingival crevicular fluid can be used as indicator of alveolar bone resorption in periodont al disease subjects.

Co-Authors Agustin Wulan Anna P. Jempormase Asam Khalifa Mohammed Budiyati, Arum Claudia K. Kawengian Cynthia E. V. Wuisang David Singal Diana S. Lahengko Endro Wahjono, Endro Esli D. Takumansang Frits O. P. Siregar Geneviene N. D. Biring Geraldy M. Anaktototy Hendriek H. Karongkong Judy O. Waani Kenny M. Pangkerego Leonardo A. Kumayas Luvesto Loloangin Nafi, Nasrul Annafi Nehemia Tirajoh Ogya J. Ingkiriwang OOctavianus H. A. Rogi Pierre H. Gosal Rachmat Prijadi Rodrigo N. Kaunang Roosje J. Poluan Runjati Siti Sunarintyas Sonny Tilaar Widjijono ,

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