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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Pembelajaran dan Biologi Nukleus Indonesian Journal of Pharmaceutical and Clinical Research Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Farmanesia Jurnal ABDIMAS MUTIARA
Yosy Cinthya Eriwaty Silalahi
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Journal : Jurnal Farmanesia

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UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli, Shigella dysentriae, DAN Salmonella typhi Sitompul, Erly; Hafizullah, Ahmad; Silalahi, Yosy Cinthya Eriwaty; Telaumbanua, Realisni
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2705

Abstract

One of the medicinal plants is the areca nut (Areca catechu L.) from the Arecae family which has the potential as an anticancer having antioxidant and antimutagenic, astringent, and anthelmintic effects. Areca nut seeds contain alkaloids, such as arekoline, arekolidine, arekain, guvakolin, guvasine and isoguvasine. This study aims to determine the characteristics of the betel nut (Areca catechu L.) simplicia, class of compounds, and the antibacterial activity of the ethanol extract of areca nut (Areca catechu L.) against the growth of Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria. The method used is the ethanol extract of areca nut (Areca catechu L.) obtained from the maceration process with 96% ethanol. The results of phytochemical screening showed that the ethanolic extract of areca nut (Areca catechu L.) contains a group of alkaloid compounds, tannins, flavonoids, saponins, and triterpenoids. The effect of giving young betel nut ethanol extract to Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria was indicated by the formation of an inhibition zone of optimum concentration. The ethanol extract of old betel nut against Escherichia coli, Shigella dysentriae, and Salmonella typhi bacteria was characterized by the formation of an optimum concentration inhibition zone. Based on the results, it can be concluded that the ethanol extract of areca nut (Areca catechu L.) has antibacterial activity against Escherichia coli, Shigella dysentriae, and Salmonella typhi.
FORMULASI DAN EVALUASI SEDIAAN LIP BALM DENGAN PEWARNA EKSTRAK UBI JALAR UNGU (Ipomoea batatas (L.) Lamk.) Supartiningsih, Supartiningsih; Sitorus, Elly Nurita; Silalahi, Yosy Cinthya Eriwaty; Khairunnisa, Khairunnisa
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2707

Abstract

Lip balm is a cosmetic preparation with the main components such as wax, fat, and oil from natural or synthesized extracts with the aim of preventing dryness of the lips by increasing lip moisture and protecting the adverse effects of the environment on the lips. The use of purple sweet potato as a dye is because purple sweet potato (Ipomoea batatas (L.) Lamk.) has an attractive color, the color of purple sweet potato is due to the presence of anthocyanin pigments which are derivatives of flavonoid compounds which are generally soluble in polar solvents. This study aims to formulate and evaluate lip balm preparations using purple sweet potato extract at concentrations of 3%, 6%, 9%, and without using purple sweet potato extract. This research is experimental research. Lip balm preparations were made by adding purple sweet potato extract with various concentrations (F1) 3%, (F2) 6%, (F3) 9%, and blank formula (F0) as the basis for lip balm preparations without purple sweet potato extract. Evaluation of the preparation includes homogeneity test, stability test, smear test, adhesion test, spreadability test, and pH test. The test results showed that purple sweet potato extract can be formulated in lip balm preparations that have a homogeneous composition, have good smearing power, good adhesion F0 (1 minute), F1 (1 minute 3 seconds), F2 (1 minute 8 seconds). seconds), F3 (1 minute 11 seconds), spreadability (5-5.7cm), pH test on all preparations showed a pH that was in accordance with the pH of the skin. And obtained formula 3 is the best formula.
PENENTUAN KONSENTRASI HAMBAT MINIMUM (KHM) DARI EKSTRAK BUAH SAWO TERHADAP Salmonella typhi Nurbaya, Siti; Silalahi, Yosy Cinthya Eriwaty; Nurussakinah, Nurussakinah; Purba, Trionaldo
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2713

Abstract

Sapodilla fruit (Manilkara zapota) belongs to the Sapotaceae family. Sapodilla fruit is traditionally used in traditional medicine to cure typhoid and sapodilla fruit is not only made medicine but also the sap is taken as raw material for making chewing gum. The purpose of the examination was to determine the minimum inhibitory concentration (MIC) of sapodilla fruit extract against Salmonella typhi bacteria. The method used is the agar diffusion method using Mueller Hinton Agar (MHA) as a growth medium and paper backing. The results of the examination of the effective inhibition at a concentration of 300mg/ml with a diameter of 15.4 mm while the minimum inhibitory concentration (MIC) was at a concentration of 50mg/ml against Salmonella typhi with the smallest inhibitory diameter of 11.5 mm. From the data above, sapodilla fruit extract has a great inhibitory power against Salmonella typhi
ANALISA KADAR CEMARAN LOGAM MERKURI PADA IKAN SARDEN (Sardinella lemuru) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Silalahi, Yosy Cinthya Eriwaty; Thaib, Cut Masyithah; Nurbaya, Siti
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2714

Abstract

Food packaging in cans is a food preservation technology using high-temperature sterilization. Mercury is a heavy metal that can have a toxic effect on the body so it can cause death. This study aims to determine the levels of mercury contamination in canned sardines. The samples used in this study were 6 different brands of canned sardines. The method used to determine mercury (Hg) levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained from 6 samples of canned sardines that were positive for heavy metal mercury (Hg) were indicated by the formation of orange color with KI reagent, yellow precipitate with NaOH, white precipitate with HCl. The wavelength used is 253.7 nm. The results showed that Brand A mercury 4.9814 ± 0.0301 mg/kg, Brand B 0.8757 ± 0.0308 mg/kg, Brand C 1.4899 ± 0 mg/kg, Brand D 1.4175 ± 0 mg/kg , Brand E 0.7527 ± 0 mg/kg, and Brand F 0.5270 ± 0 mg/kg. This study concludes that the mercury content in canned fish circulating in the Medan Brastagi Supermarket is above the maximum limit allowed by the National Standardization Agency (2016) in SNI 8222-2016, which is 0.5 mg/kg.
UJI AKTIVITAS EKSTRAK ETANOL DAUN SAWO MANILA (Manikara zapota L.) TERHADAP BAKTERI Bacillus cereus Manurung, Kesaktian; Adiansyah, Adiansyah; Silalahi, Yosy Cinthya Eriwaty; Hayati, Sry
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Sawo manila (Manikara zapota L.) merupakan salah satu bahan alam sebagai obat alternatif yang telah banyak dimanfaatkan oleh masyarakatnya juga untuk mengobati berbagai penyakit dan sawo merupakan tanaman dari family Sapotaceae yang digunakan dalam pengobatan tradisional. Ekstrak daun sawo manila mengandung alkaloid, tanin, flavonoid, dan saponin yang diketahui memiliki aktivitas antibakteri. Tujuan penulisan surat ini adalah untuk mengetahui aktivitas antibakteri sawo manila (Manikara zapota L.) terhadap bakteri Bacillus cereus. Penelitian ini menggunakan metode eksperimen, dengan metode ekstraksi maserasi dan metode chakra difusi untuk aktivitas antibakteri. Hasil penelitian menunjukkan bahwa simplisia memiliki kadar air 9,30%, larut dalam air 23,72%, kadar larut air ekstrak 31,15%, kadar abu total 1,11%, dan kadar ask tidak larut asam. 0,30%. Percobaan aktivitas anti bakteri ekstrak etanol daun sawo terhadap daya hambat bakteri bacillus cereus pada konsentrasi 20%, 40%, 60%, 80% dan 100% yaitu 12,62 mm, 15,0 mm, 15,74 mm, 16,9 mm , dan 18,78 mm, control positif menggunakan kotrimoksazol dan luas zona hambat 21,5 mm daun sawo manila dapat menghambat Bacillus cereus.
PEMERIKSAAN ZAT WARNA MERAH PADA MINUMAN BOTOL YANG BEREDAR DI SEKITAR JALAN KAPTEN MUSLIM MEDAN SECARA KROMATOGRAFI KERTAS Silalahi, Yosy Cinthya Eriwaty; Wiratma, Dicky Yuswardi; Sianipar, Artha Yuliana
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2737

Abstract

Drinks are materials that are needed by living things, which are useful for survival. Therefore, many manufacturers are innovating with drinks, one of which is bottled drinks and adding colorants to drinks to attract buyers. The purpose of this study was to determine whether or not the use of red dye is not allowed in bottled drinks sold around Jalan Captain Muslim Medan. This study uses a descriptive method, namely by conducting examinations in the laboratory. Drinks that are red were taken as samples, namely as many as 5 samples. Samples were purified using wool absorption, followed by identification using paper chromatography compared with tables. The results of the observations showed that from the 5 samples tested, none of the bottled drinks containing red dye were prohibited.
FORMULASI KRIM ANTI-AGING DARI EKSTRAK KULIT BUAH JERUK LEMON (Citruslimon) Silalahi, Yosy Cinthya Eriwaty; Sinaga, Eka Margaret; Thaib, Cut Masyithah
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Anti-aging is a preparation that is useful for preventing or slowing down the effects of aging such as wrinkles, dark spots, rough skin, and enlarged pores. Lemon peel contains flavonoids, namely hesperidin which can prevent aging and can improve skin health. This study aims to formulate anti-aging cream preparations, test the anti-aging effect, and determine the best concentration of anti-aging cream from lemon peel extract. The concentration of lemon peel extract used as a cream ingredient are: 2.5%, 5%, 7.5%, 10%. The tests carried out were homogeneity test, determination of emulsion type, pH, stability observation, skin irritation test. The test was carried out for 4 weeks. The results showed that the anti-aging cream preparations produced were homogeneous and showed an o/w type. The pH test when the cream was made was: 6-7 and after 12 weeks of storage, it was: 5-7. Anti-aging cream preparations have shown a significant increase in skin effects after 1 week, 2 weeks, 3 weeks, and 4 weeks. F5 (10% cream) provides the best anti-aging effectiveness. Lemon peel extract can be formulated into an o/a cream preparation that is able to provide anti-aging effects on the skin. Formula 5 (F5) with a concentration of 10% lemon peel extract was the most.
PENGGUNAAN PATI KENTANG (Solanum tuberosum) LOKAL PREGELATINASI SEBAGAI BAHAN PENGEMBANG PADA TABLET PARASETAMOL GRANUL SECARA KEMPA LANGSUNG Dalimunthe, Agusmal; Thaib, Cut Masyithah; Silalahi, Yosy Cinthya Eriwaty; Tarigan, Mira Eka Diana Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Potatoes have a high nutritional content such as carbohydrates, starch, fat, protein, and water. Almost 90% of medicinal raw materials, both active substances and additives are obtained through imports and abroad, even though Indonesia's natural resources can be developed. This study aims to determine the effect of using pregelatinized local potato starch (Solanum tuberosum) as a developer in paracetamol tablets by direct compression. This research was conducted experimentally using five formulas with certain concentrations of F1 (4%), F2 (6%), F3 (8%), and F4 (10%). Then the tablet evaluation test was carried out, namely the weight uniformity test, tablet hardness test, tablet friability test, tablet disintegration time test. The results showed that the paracetamol tablets with local pregelatinized potato starch developer were made to meet the requirements for weight uniformity test, tablet hardness test, tablet friability test, and tablet disintegration time test. It can be concluded that local pregelatinized potato starch (Solanum tuberosum) can be used as a developer in paracetamol tablets.
ANALISIS TIMBAL (Pb) DAN KADMIUM (Cd) PADA KERANG BULUYANG DIPEROLEH DARI PASAR SEI SIKAMBING MEDAN SECARA KUALITATIF Maimunah, Siti; Sianipar, Artha Yuliana; Zuhairiah, Zuhairiah; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2748

Abstract

Shellfish (Anadaraantiquata) is one type of shellfish that has the potential to be used as a food source in fulfilling the nutrition of the Indonesian people. Feather clams (Anadaraantiquata) belong to the class Bivalvia which are edible and have economic value. The purpose of this study was to determine the content of lead and cadmium in feather shells. Samples were taken from two fur shell traders at the Sei Sikambing market in Medan using a random sampling method with qualitative testing using disodium sulfide, potassium iodide, potassium chromate, potassium cyanide, and sodium hydroxide reagents, in accordance with work procedures. used in the Medan Regional Health Laboratory. The results showed that of the two samples tested, both samples did not contain lead (Pb) and cadmium (Cd). Keywords: Feather shells, lead (Pb), Cadmium (Cd), Qualitative.
ANALISA KADAR CEMARAN MERKURI (Hg) PADA IKAN TUNA (Thunnus sp.) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Adiansyah, Adiansyah; Silalahi, Yosy Cinthya Eriwaty; Ritonga, Ahmad Hafizullah
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2750

Abstract

Mercury is a heavy metal that can have a toxic effect on the body so that it can cause death. Mercury metal contamination in food is regulated in SNI number 7387 of 2009 regarding the Maximum Heavy Metal Limit. Some metal waste disposal ends up in river, lake, or sea waters so that metal pollution can occur in the ecosystem. This study aims to determine the levels of mercury metal contamination in canned tuna. Sample preparation was carried out using the wet digestion method with a microwave digestion device. The results of the analysis showed that from the six samples of canned tuna fish according to the maximum limit and meet the standard maximum limit of 1.0 mg/kg SNI. Mercury analysis was carried out using the AAS (Atomic Absorption Spectrophotometry) method. The wavelength used is at 253.7 nm. The results showed that the mercury in tuna brand A was 0.9030±0 mg/kg tuna brand B 0.1029±0 mg/kg, tuna brand C 0.4524±0 mg/kg, tuna brand C D 0.0967±0 mg/kg, tuna brand E 0.9567 ± 0 mg/kg, and tuna brand F 0.8034±0 mg/kg.
Co-Authors Adiansyah Adiansyah, Adiansyah Asmaradhani, Dian Dalimunthe, Agusmal Dicky Yuswardi Wiratma Ginting, Nahitma Harefa, Karnerius Hayati, Sry Hutabarat, Vitrilina Jansen Silalahi Khairunnisa Khairunnisa Lida Karo Karo Manurung, Kesaktian Marpaung, Jon Kenedy Nasution, Dinda Juita Nasution, Khairina Nurussakinah, Nurussakinah Purba, Trionaldo Purwandari, Vivi Rahmi, Sofia Rayhana, Rayhana Sianipar, Artha Yuliana Sinaga, Eka Margaret Sinaga, Lia Rosa Veronika Siti Maimunah Siti Morin Sinaga Siti Nurbaya Sitompul, Erly Sitorus, Elly Sitorus, Elly Nurita Supartiningsih - - Tambunan, Rika Puspita Tarigan, Malemta Tarigan, Mira Eka Diana Br Telaumbanua, Realisni Thaib, Cut Masyithah Turnip, Icha Wahyuni Zuhairiah, Zuhairiah