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All Journal Jurnal Berkala Epidemiologi Folia Medica Indonesiana Care : Jurnal Ilmiah Ilmu Kesehatan Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology
Hermina Novida
Department Of Internal Health, Faculty Of Medicine, Universitas Airlangga, Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : Indian Journal of Forensic Medicine

 1 
Nonsurgical Management of a Patient with Hypopituitarism Secondary to Nonfunctioning Pituitary Macroadenoma: A Case Report Martino Handoyo; Hermina Novida
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16960

Abstract

Pituitary adenoma is a benign neoplasm of pituitary gland. Pituitary adenoma, particularly a macroadenoma,may produce mass effect symptoms by compressing surrounding tissues. Due to pituitary function as aneuroendocrine organ, pituitary adenoma may also cause multiple endocrine disturbances. The authors reportthe case of a 39-year-old male patient presenting with chronic headache and history of seizure. MRI imagingrevealed pituitary macroadenoma with optic chiasm compression. Further diagnostic workup indicatedsecondary hypogonadism and adrenal insufficiency. The patient was given hormone replacement therapyand was then advised for surgery, but the patient refused any surgical procedure. Subsequent follow-upswere somewhat difficult due to poor patient adherence. Nevertheless, appropriate management of pituitaryadenoma is needed to achieve optimal result.
Diabetic Ketoacidosis in Pregnancy: A Case Report Febrian Daru Setiawan; Hermina Novida
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17498

Abstract

A 31-year-old pregnant woman complained of vomiting, shortness of breath, fever, general weakness,painful and frequent urination with sign of hypertension, tachycardia, Kussmaul breathing. Laboratorystudies showed neutrophilia, leukocytosis, hyperglycemia, hypokalemia, ketonuria, metabolic acidosis,low C-peptide, low Thyroid Stimulating Hormone, high FT4 and Staphylococcus in blood culturewas diagnosed with Diabetic Ketoacidosis, pregestational Type 1 Diabetes Mellitus, hyperemesisgravidarum, 14 weeks of pregnancy, suspect Urinary Tract Infection, hypokalemia, hypertension, andsubclinical hyperthyroidism. Besides, the patient blamed the fetus on causing the disease and financialproblem so that the patient also was diagnosed with episode of moderate depression. The patient receivedKVT1 diet therapy, fluid replacement therapy, insulin therapy, correction of hypokalemia, correctionof acidosis metabolic antibiotic and anti-hypertension. The therapies aimed to prevent maternal andfetal morbidity. Supportive psychotherapy therapy, relaxation therapy, and family psychoeducationwere also needed to improve patient’s compliant. The patient was also suggested to consult for familyplanning and glucose control before conception.
A Prediction Model of Mortality in Patients Hospitalized with Diabetic Ketoacidosis in a Tertiary Referral Hospital in Surabaya, Indonesia Hermina Novida; Fajar Setiyawan; Soebagijo Adi Soelistijo
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14751

Abstract

Background: The mortality rate of diabetic ketoacidosis (DKA) remains high in Indonesia. Differentpatterns were contributing to DKA mortality from previous studies. We aim to identify clinical and laboratoryfindings as mortality predictors of DKA.Methods: This retrospective study was conducted in a tertiary referral hospital in Surabaya. Medical recordsof DKA patients from January 2016 to December 2018 were analyzed. Clinical and laboratory data wereobtained from medical records for three years period. Clinical outcome was defined as either dischargedhome or death.Results: Fifty-six among 116 DKA patients did not survive during hospitalized. Age of 60 or older, thedepressed mental state with GCS below 13, potassium serum less than 3.5 mmol/L, and bicarbonate serumless than 15 mmol/L are found to be significant as independent factors of mortality in DKA patients.Conclusion: The mortality rate of DKA patients in this study is still high. It independently associatedwith the age of 60 years or older, depressed mental state, hypokalemia, and low bicarbonate level. Earlystratification of these predictors would help to treat patients accordingly.
In-Vitro Differentiation Adipose-Derived Mesenchymal Stem Cells into Pancreatic Progenitor Cells Hermina Novida; Agung Pranoto; Askandar Tjokroprawiro; Sony Wibisono; Purwati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14752

Abstract

Background: Adult stem cells are currently reliable sources of mesenchymal stem cells for regenerativetherapy, include diabetes mellitus. The aim of this study is to develop endocrine pancreatic progenitor cellscharacterized by Pdx1 and insulin expression from rat adipose-derived mesenchymal stem cells using twosteps in-vitro differentiation.Methods: In this experimental study, ADMSCs were isolated from rat adipose tissue and exposed toinsulinogenic differentiation medium containing nicotinamide, activin A and glucagon-like peptide-1 (GLP1). After induction, the existence of pancreatic progenitor cells (PPCs) was confirmed by immune-stainingassay of Pdx1 and insulin.Results: After three weeks of in-vitro differentiation, expression of Pdx1 and insulin proteins showed upas green in the immunofluorescence assay. Immunofluorescence intensity of Pdx1 was higher in PPCs thanin ADMSCs control (p<0.05). Immunofluorescence intensity of insulin was also higher in PPCs than inADMSCs control (p<0.05). Therefore, in-vitro differentiation was successful to develop PPCs from ratADMSCsConclusion: This study has demonstrated the in-vitro differentiation of ADMSCs into PPCs that expressedPdx1 and insulin
Overview of Lifestyle and Anthropometry of Students of the Faculty of Medicine Airlangga University During COVID-19 Pandemic Jihadna Prima Santika Ruslan Musanip; Hermina Novida; Gadis Meinar Sari; Reny I’tishom
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 3 (2022): Indian Journal of Forensic Medicine and Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i3.18283

Abstract

Background: The COVID-19 pandemic has spread worldwide, forcing governments to implement quarantines asa preventive measure against the spread of the virus. Quarantine causes changes in lifestyle and anthropometrystatus among communities.Objective: To describe the lifestyle and anthropometric status of medical students batch 2018 FM UA during thepandemic. Methods: This was a descriptive study using online questionnaires from September 2020 to February2021.Results: There were variations in students’ anthropometry. Students’ average height is 161.110 cm, the averageweight is 60.308 cm, the average body mass index is 23.193 cm, the average upper arm circumference is 27.846 cm,and the average abdominal circumference is 79.621 cm. Furthermore, 145 respondents (81.9%) stated that theyexperienced changes in their lifestyle during the pandemic. A total of 89 respondents (50.3%) continued to exerciseand the other 88 respondents (49.7%) did not. Regarding the sleep pattern, 108 respondents (61%) had quitegood sleep quality and 50 respondents (28.2%) had quite poor sleep quality. For the food consumption pattern,46 respondents (26%) ate more sweet foods. Furthermore, 156 respondents (88.1%) did sedentary activities, with77 respondents (43.5%) doing sedentary behavior for more than 6 hours a day.Conclusion: During the COVID-19 pandemic, the anthropometric status of medical students batch 2018 FMUAvaried; and tend to maintain their physical activity, have quite good sleep quality, prefer eating sweet foods, anddo a sedentary behavior for a longer duration
Co-Authors AGUNG PRANOTO Alviano Satria Wibawa Anandia Nafisah Putri Andriati Andriati Ari Sutjahjo Arisvia Sukma Hariftyani Aryati Aryati Askandar Tjokroprawiro Caesar Lagaliggo Givani Deasy Ardiany Delfitri Lutfi Desak Gde Ushadi Bulan Dewata Dian Galuh Maharani Dian Ristanti Dicky Febrianto Drestha Pratita Windriya Fajar Setiyawan Febrian Daru Setiawan Gadis Meinar Sari Gatot Soegiarto HERAWATI, LILIK I'tishom, Reny Indira Syahraya Jihadna Prima Santika Ruslan Musanip kholidatul husna Martino Handoyo Meisy Andriana, Meisy Mouli Edward Muhammad Faizi Nurul Bashirah Aminy Pawana, I Putu Alit Purwati Purwo Sri Rejeki Puspa Wardhani Rizki Adrian Hakim Soebagijo Adi Soelistijo Soenarnatalina Melaniani Sony Wibisono Stepanus Massora Troy Fonda