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All Journal JURNAL WIDYA MEDIKA Majalah Obstetri dan Ginekologi Molecular and Cellular Biomedical Sciences (MCBS) Halaman Olahraga Nusantara : Jurnal Ilmu Keolahragaan JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga International Islamic Medical Journal INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL JKKI : Jurnal Kedokteran dan Kesehatan Indonesia

Aditiawarman -

Airlangga University

Author-ID : 2410124

Religion Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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THE CORRELATION BETWEEN APGAR SCORE AND GESTATIONAL AGE WITH NEONATAL SEPSIS AND ASSOCIATED MORTALITY Nabila Annisa Harum; Martono Tri Utomo; Aditiawarman -; Prastiya Indra Gunawan
JURNAL WIDYA MEDIKA Vol 7, No 2 (2021): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v7i2.3388

Background: Neonatal sepsis is increasingly recognized as an important global health problem that challenges neonatal survival. In 2018, sepsis caused approximately 15% of all neonatal deaths worldwide. Recent data regarding preterm birth and low Apgar score as risk factors for neonatal sepsis-related death have not been reported in Indonesia. Methods: This was a case-control study conducted in Dr.Soetomo General Hospital. A case group was obtained from medical records by a total sampling of all neonates diagnosed with neonatal sepsis in 2019, and a control group of non-neonatal sepsis cases was taken by random sampling. Chi-square test and logistic regression were used to analyze the data. Results: Statistical analysis showed a significant correlation between one and five-minute Apgar score

25(OH)D Inadequacy Has Different Pathway with VEGF in Increases the Risk of Severe Preeclampsia Hanifa Erlin Damayanti; Aditiawarman Aditiawarman
Majalah Obstetri dan Ginekologi Vol. 23 No. 2 (2015): Mei - Agustus 2015
Publisher : Universitas Airlangga

Objectives: To identify in vivo correlation between 25(OH)D and VEGF in severe preeclampsia.Materials and Methods: A case control, cross sectional study of 36 pregnant women which consist of 18 patients with preeclampsia and 18 patients as control with gestational age-matched. We perform 25(OH)D serum examination by chemiluminescent immunoassay (CLIA) and VEGF serum examination by sandwich ELISA to all patients.Results: All patients are in 25(OH)D insufficiency and deficiency state. Both maternal 25(OH)D and VEGF levels were inversely associated with the risk of preeclampsia (both P<0.05). There is no correlation between 25(OH)D serum level and VEGF serum level (P=0,629).Conclusion: Maternal vitamin D deficiency is associated with increased preeclampsia risk. However, our data do not support the hypothesis that the association between vitamin D deficiency and preeclampsia is mediated by impaired level of VEGF.

Comparison of serum soluble edoglin (sEng) level in eary onset preeclampsia, late onset preeclampsia and normal pregnant woman Aldika Akbar; Mita Herdiyantini; Aditiawarman Aditiawarman
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Objectives: This study aimed to compare the serum levels of soluble Endoglin (s-Eng) between early onset preeclampsia, late onset preeclampsia and normal pregnant women.Materials and Methods: This was an analytic observational study (Cross-Sectional) performed on 39 pregnant women with early-onset preeclampsia (EO-PE), late-onset preeclampsia (LO-PE), and normal pregnancy. The patients were consecutively chosen in Dr. Soetomo Hospital, Airlangga University Hospital and Dr. M. Soewandhi Hospital Surabaya in May-July 2016. The serum concentration of soluble Endoglin were collected by venous puncture taken from maternal circulation and measured by ELISA.Results: From this study, serum concentrations of soluble Endoglin was higher significantly on the early onset preeclampsia compared with late onset preeclampsia and normal pregnancy (47,65 ± 40,17 vs 13,46 ± 9,48 vs 6,11 ± 1,45 ng/mL; p=0.000). Conclusion: This study shows angiogenic imbalance was more prominent compared in early-onset than late-onset preeclampsia. This may be because the placental dysfunction, placental ischemia, which produce excessive anti angiogenic factors, whic later causing endothelial dysfunction was more related to early onset preeclampsia.

Profile of pregnant women with preeclampsia and its termination method Vebianti Permadi; Aditiawarman Aditiawarman; Pudji Lestari
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.10-16

HIGHLIGHTS 1. Pregnancy with preeclampsia in this study was mostly terminated by cesarean section. A small percentage was with vaginal delivery.2. Most preeclamptic mothers gave birth by cesarean section exhibited severe symptoms of preeclampsia, such as severe hypertension, severe proteinuria, and visual impairment. ABSTRACT Objectives: To determine the symptoms of pregnant women with preeclampsia through the method of pregnancy termination. Materials and Methods: This study used a cross-sectional method for descriptive analysis. The total sample included 75 pregnant women with preeclampsia. The sampling techniques was carried out with purposive sampling. This study used auxiliary data in medical records of preeclampsia mothers who gave birth at Taman Husada Regional Hospital, Bontang, Indonesia, in 2019. Results: The results showed that most preeclampsia mothers delivered by cesarean section (CS). Among mothers who gave birth by cesarean section, there were severe symptoms of preeclampsia, 74.14% had severe hypertension with systolic blood pressure of > 160 mmHg or diastolic blood pressure of > 110 mmHg. Those with severe proteinuria with urine protein > 2g/24 hours or > +2 were 82.76% and 60.35% of those complained visual impairment with blurred vision. Conclusion: These data indicated that most mothers with preeclampsia gave birth by cesarean section and exhibited severe symptoms of preeclampsia.

The Maternal Risk Factors for Preterm Birth in Universitas Airlangga Hospital Surabaya in 2017-2018 Almira Maharani; Aditiawarman Aditiawarman; Widati Fatmaningrum
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 1 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I12022.31-37

Introduction: Preterm birth becomes a global problem due to its high rate of morbidity and mortality. In 2010, it is estimated approximately 15 premature birth cases per 100 lives birth in Indonesia. This study aimed to analyze the maternal risk factors towards preterm birth at Universitas Airlangga Hospital Surabaya in 2017-2018.Methods: This was observational analytic study using case-control approach to observe 178 medical records at Universitas Airlangga Hospital Surabaya. The population of this study was women who had preterm and aterm birth. The sample consisted of case group and control group which were convenient to exclusion and inclusion criteria. Univariate analysis was used to observe the relationship between dependent and independent variable. The significance value was p ≤ 0.05. The data were analysed using SPSS.Results: The research samples consisted of 89 case groups and 89 control groups. The case sample characteristic showed that 36% patients had overweight BMI; 62.9% patients had normal/hypotension; 69.7% patients gave birth to male baby; and 82% patients had no history of disease.There was no patient who used drugs and substance abuse (0%). Mothers aged 20 years old and older than 35 years old had OR = 2.13 (95% CI : 1.106-4.11) to become preterm birth. The primiparous women had risk for preterm birth 2.978 folds (95%, CI : 576-5.625) higher.Conclusion: There was a relationship between maternal age and parity to preterm birth. There was no relationship between maternal education, maternal occupation, hemoglobin levels, history of obstetric complications, and multiple pregnancy to preterm birth.

Clinical Characteristic of Congenital Fetal Anomaly In Tertiary Referral Hospital in East Java, Indonesia Fariska Zata Amani; Wardhana M. P; Cininta N. I; Aryananda R. A; Gumilar K. E; Aldika M. I; Wicaksono B; Ernawati Ernawati; Sulistyono A; Aditiawarman Aditiawarman; Hermanto T. J; Abdullah N; Dachlan E G
Jurnal Medis Islam Internasional Vol 2 No 2 (2021): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v2i2.1624

Background: Congenital fetal anomalies were defined as any structural defect present at birth. Congenital fetal anomalies are an important causes of neonatal morbidity and mortality in developed and developing countries that affect health care system. Reliable data on these congenital anomalies are still lacking, especially in Indonesia. Objective: This study aims to determine the characteristic profile of congenital fetal anomaly in single tertiary hospital in East Java, Indonesia. Methods: Retrospective cross-sectional by using medical record data of dr. Soetomo General Hospital on January – December 2017. Results: There were 58 cases (4,3%) with fetal congenital anomaly from 1360 deliveries in 2017. The majority of cases were referral cases (51 cases; 88%) and only seven cases were booked cases in obstetric outpatient dr. Soetomo General Hospital. Most of these congenital fetal anomaly cases ( 25 cases / 43,1%) were born from mother with ages 20 – 30 years old. Most cases (34 cases; 58,64%) were diagnosed first at third trimester (gestational age > 28 weeks). There were 36 cases (62%) had active termination of pregnancy. Thirty eight percent (22 cases) were born at 37-42 weeks and majority were born section caesaria. The three highest proportion of organ systems involved in fetal congenital anomalies were those of abdomen (22 cases; 37,9%); head (20 cases; 34,5%); thorax and muskuloskeletal (each 12 cases; 20,7%). Conclusion: The incidence of congenital fetal anomaly in dr. Soetomo Hospital at 2017 was 4,3%. Omphalocele and CTEV were two most common types of congenital fetal anomaly found. Most cases of congenital fetal anomalies have a poor prognosis, 67% cases born died. Further research about risk factors and comprehensive database are needed on cases of congenital anomaly to establish appropriate prevention and management.

Plasma Level of Umbilical Cord Hemeoxygenase-1 (HO-1) and Neonatal Outcome in Early Onset and Late Onset Severe Preeclampsia Muhammad Ilham Aldika Akbar; Indah Mayang Sari; Ernawati Ernawati; Aditiawarman Aditiawarman
Molecular and Cellular Biomedical Sciences Vol 3, No 1 (2019)
Publisher : Cell and BioPharmaceutical Institute

Background: Many studies had discovered that early onset severe preeclampsia (EO-PE) has worst maternal and neonatal outcome compared to late-onset type (LO-PE), related to its placental involvement. Severe preeclampsia was defined as newly onset severe hypertension developed after 20 weeks gestation in previously normal blood pressure women, with coexistence of proteinuria, or maternal organ or uteroplacental dysfunction. Hemeoxygenase-1 (HO-1) is an enzyme with multiple effect which is protective to pregnancy.Materials and Methods: The total study subjects were 40 pregnant women consisted of 10 EO-PE, 10 normal early onset pregnancy (EO-NP), 10 LO-PE, and 10 normal late onset pregnancy (LO-NP). As much as 5 cc of plasma from umbilical cord was taken as soon as the baby was born, and the HO-1 level was examined by enzyme-linked immunosorbent assay (ELISA). The primary outcome were umbilical cord HO-1 level and neonatal composite morbidity (low Apgar score, low birthweight, length of stay >5 day, respiratory distress syndrome, jaundice and neonatal death).Results: The plasma level of HO-1 in EO-PE subjects were lower than EO-NP (0.96±0.37 ng/mL vs. 2.43±0.58 ng/mL, p<0.001). There were no significant differences in the level of HO-1 in LO-PE and LO-NP (2.18±1.07 ng/mL vs. 3.02±0.64 ng/mL, p=0.277). Plasma level of umbilical cord HO-1 of EO-PE patients was lower compared to LO-PE (0.96±0.37 ng/mL vs. 2.18±1.07 ng/mL, p=0.034). Neonatal outcome of EO-PE was worse than EO-NP (p=0.033), and LO-PE (p=0.003), while in LO-PE did not different with LO-NP (p=0.211).Conclusion: EO-PE is associated with lower plasma umbilical cord level of HO-1 and worse neonatal outcome compared to LO-PE. This indicating abnormal placental blood vessel development, placental ischemia in EO-PE, lead to reduced uteroplacental perfusion and significantly worse neonatal outcome compared to LO-PE.Keywords: severe preeclampsia, early onset preeclampsia, late onset preeclampsia, hemeoxygenase-1

The Effect Of Progressive Muscle Relaxation and Slow Deep Breathing Combinations on Sleep Quality of Pregnant Women Mufidah Sheena Andani Prastini; Lilik Herawati; Endyka Erye Frety; Aditiawarman Aditiawarman
Halaman Olahraga Nusantara : Jurnal Ilmu Keolahragaan Vol 5, No 1 (2022): Halaman Olahraga Nusantara (Jurnal Ilmu Keolahragaan)
Publisher : Universitas PGRI Palembang

Several studies suggest that poor sleep quality has an impact on both the mother and the fetus. Providing relaxation exercises in the form of progressive muscle relaxation and slow deep breathing can be a non-pharmacological effort to improve sleep quality in pregnant women. This study aims to analyze the effect of a combination of progressive muscle relaxation and slow deep breathing in pregnant women of third trimester. This research method is pre-experimental designs with a pretest-posttest control group design. The number of samples was 24 pregnant women trimester III with the sampling technique using consecutive sampling. The independent variable is the provision of progressive muscle relaxation and slow deep breathing exercises which are carried out for 3 times on a week over a period of 3 weeks. The dependent variable is sleep quality which is measured using the Pittsburgh Sleep Quality Index questionnaire. Data analysis used the Wilcoxon signed rank test. The results showed a decrease in the mean value in the direction of improved sleep quality by a difference of 4.5 in the experimental group. Whereas in the control group there was an increase in the value which led to a deteriorating sleep quality by a difference of 1.42. The test results showed a difference in the pretest and posttest of the two groups p = 0.000 (p <0.05). These data indicate that there is an effect of a combination of progressive muscle relaxation and slow deep breathing on the sleep quality pregnant women of third trimester.

FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN PERSALINAN PREMATUR DI RSUD DR SOETOMO Noza Loviana; Ninik Darsini; Aditiawarman Aditiawarman
Indonesian Midwifery and Health Sciences Journal Vol. 3 No. 1 (2019): Indonesian Midwifery and Health Sciences Journal, January 2019
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v3i1.2019.85-97

AbstrakLatar Belakang: Secara global, persalinan preterm menjadi penyebab utama kematian neonatus usia dini 0-7 hari pertama kehidupan dengan menimbulkan dampak morbiditas yang tinggi juga. Indonesia menempati urutan negara ke 5 estimasi persalinan preterm tertinggi di dunia. Beberapa faktor yang dapat berpengaruh terhadap persalinan preterm yaitu idiopatik, iatrogenik, sosio-demografi, maternal dan genetik. Penelitian ini bertujuan untuk melihat hubungan antara usia ibu, pendidikan ibu, pekerjaan ibu dan riwayat persalinan preterm terhadap kejadian persalinan prterm di RSUD Dr. Soetomo Surabaya. Metode: Metode penelitian ini adalah analitik observasional dengan rancang bangun case control. Jumlah populasi sebanyak 1311 orang pada periode 1 Januari - 31 Desember 2018. Sampel dibagi dalam dua kelompok yaitu kelompok kasus (ibu yang bersalin preterm) dan kelompok kontrol (ibu yang bersalin tidak preterm) sebanyak masing-masing kelompok 137 orang yang disesuaikan dengan kriteria inklusi dan eksklusi dan berdasarkan teknik pengambilan sampel yaitu simpel random sampling. Variabel independen terdiri dari usia ibu, pendidikan, pekerjaan dan riwayat persalinan preterm sedangkan variabel dependen adalah persalinan preterm. Analisis data bivariat menggunankan uji Chi-Square test dengan taraf signifikansi α = 0,05 (95% CI). Hasil: Hasil uji Chi-Square menunjukkan bahwa tidak ada hubungan bermakna antara usia ibu bersalin (nilai p = 0,259), pendidikan (nilai p = 1), pekerjaan (nilai p = 0,225) dan riwayat persalinan preterm (nilai p = 0,191) dengan kejadian persalinan preterm. Kesimpulan: Faktor risiko seperti usa ibu bersalin, pendidikan ibu, pekerjaan ibu dan riwayat persalinan preterm tidak memiliki hubungan terhadap kejadian persalinan preterm. Abtract Background : Globally, preterm labor is the main cause of neonatal mortality in the first 0-7 days of life with a high impact of morbidity. Indonesia ranks 5th in the highest estimate of preterm labor in the world. Several factors that can influence preterm labor are idiopathic, iatrogenic, socio-demographic, maternal and genetic. This study aims to look at the relationship between maternal age, maternal education, maternal occupation and a history of preterm labor against the incidence of prenatal labor in RSUD Dr. Soetomo Surabaya. Method : The method of this study is observational analytic with a case-control design. The total population is 1311 people in the period January 1 - December 31, 2018. Samples were divided into two groups, namely the case group (preterm maternity) and the control group (mothers who were not preterm) as many as 137 groups each according to the inclusion criteria and exclusion and based on sampling techniques, namely simple random sampling. Independent variables consisted of maternal age, education, occupation and a history of preterm labor while the dependent variable was preterm labor. Bivariate data analysis used the Chi-Square test with a significance level of α = 0.05 (95% CI). Results : The Chi-Square test results showed that there was no significant relationship between maternal age (p = 0.259), education (p = 1), employment (p = 0.225) and preterm labor history (p = 0.191) with the incidence of preterm labor. Conclusion: Risk factors such as maternal age, maternal education, maternal occupation and a history of preterm labor have no relationship to the incidence of preterm labor.

THE QUALITY OF ANTENATAL CARE BASED ON INDEX SATISFACTION OF PREGNANT WOMEN Nurmaliatul Firdaus; Aditiawarman Aditiawarman; Dwi Izzati Budiono
Indonesian Midwifery and Health Sciences Journal Vol. 5 No. 1 (2021): Indonesian Midwifery and Health Sciences Journal, January 2021
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v5i1.2021.62-72

AbstractBackground: Quality antenatal care in the MCH program is considered to be one of the effective efforts to reduce maternal and child morbidity and mortality. An indicator of the success of ANC services can be seen from the output produced, namely in the form of K4 coverage. According to Kotler there are 5 (five) determinants of service quality that can be used as a basis for assessing the level of customer satisfaction with the quality of service received including Tangibles, Reliability, Responsiveness, Assurance and Empathy. Method: This research method is quantitative descriptive with survey approach. The total sample of 149 pregnant women with total sampling techniques. The instrument used was a questionnaire. Data analysis uses univariate analysis. Results: The most valued statements both from each dimension namely; tangible: Midwife performance reliability: recording in the MCH handbook, responsiveness: responses to complaints, assurance: the nature of the Midwife, empathy of communication between midwives and patients. The most valued statements are enough from each dimension namely; tangible: examination room, reliability: service procedures, responsieness: midwife response to patients waiting for long queues, assurance: guarantee to service, empathy: suitability of waiting time and duration of service. Conclusion: The data shows that the majority of respondents considered the quality of antenatal services at the Tambakrejo Public Health Center to be good but still needed to be improved so that the assessment was sufficiently good.

Co-Authors Abdullah N Aldika Akbar Aldika M. I Almira Maharani Aryananda R. A Chiquita Febby Pragitara Cininta N. I Dachlan E G Endyka Erye Frety Ernawati Ernawati Fariska Zata Amani Fitri Indah Pratiwi Gumilar K. E Hanifa Erlin Damayanti HERAWATI, LILIK Hermanto T. J I'tishom, Reny Indah Mayang Sari Izzati Dwi Martono Tri Utomo Mita Herdiyantini Mufidah Sheena Andani Prastini Muhammad Ilham Aldika Akbar Nabila Annisa Harum Ninik Darsini Noza Loviana Nurmaliatul Firdaus Prastiya Indra Gunawan Pudji Lestari Risa Etika, Risa Sulistyono A Vebianti Permadi Wahyul Anis Wardhana M. P Wicaksono B Widati Fatmaningrum

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