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All Journal Althea Medical Journal Majalah Obstetri dan Ginekologi Molecular and Cellular Biomedical Sciences (MCBS) Indonesian Journal of Obstetrics & Gynecology Science JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Pediomaternal Nursing Journal Jurnal Layanan Masyarakat (Journal of Public Service) Indian Journal of Forensic Medicine & Toxicology INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL KESANS : International Journal of Health and Science
Muhammad Ilham Aldika Akbar
Departemen Obstetri GInekologi Fakultas Kedokteran Universitas Airlangga, Surabaya, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Risk Factor of Preeclampsia in a Secondary Indonesian Hospital: A Case-Control Study Lady Aqnes Kurniawati; Muhammad Ilham Aldika Akbar; Budi Utomo; Aditiawarman
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15839

Abstract

Background: Preeclampsia is a form of hypertension in pregnancy that leads to morbidity and mortality.Although the etiology remains unclear, there are some risk factors that are suspected to be associated withthe development ofpreeclampsia. Objective: To find out the risk factors associated with the incidence ofpreeclampsia inAirlangga University Hospital. Method: This studyconducted an analytical-observationalstudy with the hospitalized unmatchedbased case-control approach. 165 pregnant women were included.Data were analyzed in univariate, bivariate, and multivariate regression logistic and performed usingstatistical package for the social science (SPSS), p < 0.05 was considered statistically significant. Results:Pregnant women with preeclampsia were about 18 to 44 years old, with the average BMIis 31.19 kg/m2.There are significant relation between family history of hypertension (p = 0.000), maternal age (p = 0.004),BMI (p = 0.000), pregnancy interval (p = 0.009), and chronic hypertension (p = 0.007) with the incidenceof preeclampsia. In the multivariate analysis using logistic regression, family history of hypertension wasthe most dominant factor with OR: 3.374 and 95% CI: 1.454 – 7.830 compared to other factors such asmaternal age (OR: 2.885; 95% CI: 1.311 – 6.347; p: 0.008) , and BMI (OR: 2.590; 95% CI: 1.525 – 4.400;p: 0.000). Conclusion: Family history of hypertension, maternal age, BMI, pregnancy interval, and chronichypertension have a significant relationship with the incidence of preeclampsia. In multivariate analysis,family history of hypertension is the most dominant risk factor among others.
Readiness of Health Workers to Provide Pregnancy Planning Program for Women Infected with Human Immunodeficiency Virus: A Case Study in Surabaya, East Java, Indonesia Made Chindy Dwiyanti Marheni Putri; Pudji Lestari; Muhammad Ilham Aldika Akbar
Althea Medical Journal Vol 8, No 1 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n1.2087

Abstract

Background: The prevalence of human immunodeficiency virus (HIV) mother-to-child infection, or vertical transmission of HIV, in Indonesia is about 90%. Ministry of Health of the Republic of Indonesia Regulation No. 21 of 2013 stated that HIV infection in sexual productive age needs integrative professional help to lower the transmissions, including voluntary counseling and testing for pregnant women as well as all people at risk. This study aimed to determine the readiness of health workers to provide pregnancy planning program service for women with HIV.Methods: This study was a descriptive study involving 30 obstetricians and 30 residents of Obstetrics and Gynecology specialist education in Surabaya, Indonesia. The respondents’ knowledge on pregnancy planning for HIV-infected women based on based on guidance released by the Ministry of Health of Indonesia in 2017 and Regulation of Ministry of Health no. 52 the year 2017, as well as their attitude and readiness to provide pregnancy planning services, was explored. Questionnaires were distributed from August to December 2019 and the data collected were analyzed using Statistical Package for the Social Science (SPSS) version 17.0 and results were described in percentage.Results: Most health workers (80%) had good knowledge on providing pregnancy planning program for HIV positive women; however, only 63.3% had good attitude towards it. The majority of respondents (90%) were ready to help HIV patients in planning their pregnancy. Conclusion: Health workers in Surabaya are ready to provide services related to pregnancy planning for women infected with HIV.
Risk factor of severe preeclampsia in Dr. Soetomo Hospital Surabaya in 2015 Amelia Rahmah Kartika; Muhammad Ilham Aldika Akbar; Pirlina Umiastuti
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.08 KB) | DOI: 10.20473/mog.V25I12017.6-9

Abstract

Objectives: to determine which of the risk factors above associated with the occurrence of severe preeclampsia at dr. Soetomo Hospital, Surabaya during 2015.Materials and Methods: The type and design of the study were analytic and retrospective. This study was held in the dr. Soetomo Hospital from April until November 2016. The instrument of the study was the medical records then being coded and analysed. The samples were 134 pregnant women, consisting of 67 pregnant women with severe preeclampsia as cases and 67 pregnant women as controls.Results: Maternal obesity (OR= 5,786; 95% CI: 2,300–14,555), history of hypertension (OR= 6,693; 95% CI: 1,848–24,237) and secondary elderly primi (OR= 6,384; 95% CI: 1,357–30,031) are associated with the development of severe preeclampsia.Conclusion: In conclusion, the significant risk factors of severe preeclampsia in dr. Soetomo Hospital Surabaya during 2015 are obesity, history of hypertension and secondary elderly primi variables.
Difference of calcium levels in Javanese, Madurese, and Chinese preeclamptic women Nuzulul Azizah Ramdan Wulandari; Ernawati Ernawati; Muhammad Ilham Aldika Akbar
Majalah Obstetri dan Ginekologi Vol. 25 No. 3 (2017): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.045 KB) | DOI: 10.20473/mog.V25I32017.86-91

Abstract

Objectives: To analyse difference of calcium levels and charac-teristics between Javanese, Madurese, and Chinese pre-eclamptic women that affects preeclampsia incidence.Materials and Methods: This was a cross-sectional study with preeclamptic patients in Dr. Soetomo Hospital, Dr. M. Soewan-dhie Hospital, and Universitas Airlangga Hospital as sample. Sample was taken by measuring total calcium level in blood serum before receiving MgSO4 using in vitro clinical chemical dimension method in the Laboratory of Clinical Pathology in Dr. Soetomo Hospital. Sample was taken using consecutive sampling. Sample size 53 preeclamptic women as participants of this study, divided into three groups of Javanese, Madurese, and Chinese.Results: There were 53 preeclampsia patients, with mean ages: Javanese 31.21±5.76, Madurese 34.20±5.58, and Chinese 28.20 ±2.16. Mean BMI: Javanese 31.19±5.99, Madurese 27.66±4.74, and Chinese 26.24±2.13. We found significant difference in total calcium levels. In Madurese it was 7.7 mg/dL, Javanese was 8.3 mg/dL, and Chinese was 9.0 mg/dL (p=.000).Conclusion: The highest severity of preeclampsia was in the Madurese with low calcium levels. The lowest the calcium level, the worst the severity of the preeclampsia.
Is it time to start COVID-19 vaccination in pregnant women? Muhammad Ilham Aldika Akbar
Majalah Obstetri dan Ginekologi Vol. 29 No. 2 (2021): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V29I22021.84-90

Abstract

HIGHLIGHTS1. Pregnant women infected with COVID 19 have a higher risk of maternal fetal mortality and morbidity.2. The available evidences show a safety profile in all type of COVID vaccines in pregnancy.3. Vaccination in pregnant women will decrease pregnancy complications, adverse pregnancy outcomes, and maternal death risk.4. The benefit of COVID vaccination exceeds the potential risk in pregnant women.5. Pregnant women are strongly recommended to receive COVID vaccine. ABSTRACTCOVID-19 pandemic has been lasting for years, and pregnant women encounter an increased risk of mortality and morbidity. Until now, vaccine COVID-19 has been developed and shows a promising result. Unfortunately, pregnant women are consistently excluded from receiving a new vaccine. Because pregnant women are excluded from participating in a clinical trial of vaccines related to safety issues, this exclusion cycle prevents pregnant women from receiving the vaccine that may benefit them. In this review article, the author provides evidence, data, and the reason why vaccination of pregnant women should be started in Indonesia, at least in a clinical trial, especially for health workers and women with comorbidities.
Low-Hemoglobin Levels During Pregnancy with Low-Birth Weight: A Systematic Review and Meta-Analysis Lucyana Septia Pramita; Widati Fatmaningrum; Martono Tri Utomo; Muhammad Ilham Aldika Akbar
Pediomaternal Nursing Journal Vol. 7 No. 1 (2021): VOLUME 7 NO 1 MARCH 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/pmnj.v7i1.24184

Abstract

Introduction: Low birth weight (LBW)  is one of the main risk factors for neonatal morbidity and mortality. Anemia in developing countries is still quite high compared to developed countries. Low hemoglobin levels in pregnancy can affect the birth of low birth weight babies.Methods: This study used a systematic review method. Studies published between 2015 and 2019. Search for articles was reviewed systematically through Scopus, ScienceDirect, Cochrane, and PubMed databases. The final results obtained 10 articles following the inclusion and exclusion criteria. Calculation result using Meta-Analysis with help of Comprehensive Meta-Analysis (CMA) software.Results: Compare the odds ratio and confidence interval of hemoglobin levels compared to low birth weight events. The results obtained OR 1.449 (95% CI 0.964 – 2.177) and p-Value 0.074 so that there is no relationship of hemoglobin levels in pregnant women ≤ 11gr / dL with the incidence of low birth weight babies. In the heterogeneity test results, I-Squared results obtained by 79.191%, which indicates the value of I-squared heterogeneity> 50% so that the sample used is heterogeneous. Maternal age less than 20 years or more than 35 years, number of parity, pregnancy spacing, and number of problems in the assessment of pregnancy and previous labor.Conclusion: There is no correlation between low maternal hemoglobin levels with the incidence of low birth weight because there are other factors that can affect outcomes such as different respondent characteristics, number of samples, different research countries, different trimester of pregnancy and other factors that can cause research bias.
Correlation between Anemia and Preeclampsia in Universitas Airlangga Hospital in 2017 Haris Rasyid Ridho; Muhammad Ilham Aldika Akbar; Widati Fatmaningrum; Budi Santoso
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 12 No. 2 (2021): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V12I22021.66-71

Abstract

Introduction: One of the causes of acute kidney injury that is increasingly soaring is preeclampsia syndrome. Globally, the maternal mortality rate reaches 287,000 per year, and preeclampsia is a major contributor. From East Java Provincial Health Office data, per 100,000 pregnancies, 114 had preeclampsia syndrome. Anemia is one of the highest causes of maternal death, the global prevalence of anemia in pregnant women reaches 55.9%. There have not been many significant studies on the effect of anemia with the incidence of preeclampsia.Methods: This was observational analytic study with a case and control design which used a chi-square and fisher exact measurement tool. The data samples were patients of pregnant women who had preeclampsia syndrome categorized as cases, and those who did not have preeclampsia were categorized as controls. The data has been obtained from medical records; these include ages, the number of parities, the number of pregnancies, body mass index (BMI), the number of childbirths, types of preeclampsia, and hemoglobin levels. The data has been obtained from the result of the medical record observations that were processed and analyzed in descriptive of statistics which used percentage and cross tab.Results: The case study group or preeclampsia pregnant women who experienced anemia were 34 patients or 50% of 68 pregnant women and in the control group were 53 patients or 39% of anemia patients out of 136 patients. The chi-square statistical test obtained values (p = 0.133). The samples needed were 68 case groups and 136  cases as controls.Conclusion: There was no relationship between anemia and preeclampsia.
Early- and Late-Onset Preeclampsia at a Tertiary Hospital in 2016 Hapsari Kinanti; Muhammad Ilham Aldika Akbar; Pudji Lestari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 1 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I12022.6-8

Abstract

Introduction: Preeclampsia is still one of the major causes of maternal morbidity and mortality worldwide. Preeclampsia nowadays has another classification, early-onset preeclampsia and late-onset preeclampsia. This study aimed to evaluate the differences between early-onset and late-onset preeclampsia in Dr. Soetomo General Hospital, Surabaya in 2016.Methods: This was an analytic observational study, evaluating the difference between early- and late-onset preeclampsia in terms of maternal data, medical history, and obstetric history. The samples were taken from the medical record of Dr. Soetomo General Hospital, Surabaya from January until December 2016.Results: In maternal data, early- and late-onset preeclampsia mostly happened in productive age, consisted of 34 patients of early-onset preeclampsia (77.3%) and 31 patients of late-onset preeclampsia (73.8%). Early-onset preeclampsia tended to happen in nullipara (42.2%) and primigravida (35.6%) women, and late-onset preeclampsia usually happened in multipara (43.9%) and multigravida (85.4%) women. In medical and obstetric history, early-onset preeclampsia mostly had a history of hypertension (61.7%), rather than late-onset preeclampsia (32.7%). Moreover, there were no significant differences in other variables.Conclusion: Early-onset and late-onset preeclampsia had a significant difference in parity, gravidity, and hypertension disease.
KNOWLEDGE IMPROVEMENT AMONG MIDWIVES AS CHAMPIONS IN THE PREVENTION AND MANAGEMENT OF MATERNAL COVID CASES IN EAST JAVA Muhammad Ardian Cahya Laksana; Muhammad Ilham Aldika Akbar; Dwi Izzati
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 5 No. 2 (2021): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v5i2.2021.333-337

Abstract

AbstrakTingginya angka kematian ibu disebabkan oleh masalah kualitas pelayanan kesehatan yang dipengaruhi oleh faktor organisasi, personal dan lingkungan (Kemenkes, 2018a; Mahmood et al., 2018). Pandemi Covid-19 di Indonesia terus berlanjut, dan kemungkinan akan menyebabkan peningkatan kematian ibu lebih lanjut, sehingga diperlukan kepemimpinan dan bantuan klinis. Metode yang digunakan dalam program pengabdian masyarakat ini adalah dengan memberikan pelatihan dan pendampingan kepada bidan dalam pencegahan dan penanganan kasus ibu hamil di rumah sakit. Pelatihan ini berhasil meningkatkan pengetahuan bidan tentang penanganan kasus covid ibu, pencegahan dan kepemimpinan bidan dalam pelayanan ibu sebesar 35%. Implikasi dari hasil pengabdian kepada masyarakat ini adalah perlu adanya pelatihan pengetahuan dan keterampilan bidan dalam penanganan kasus ibu covid pada masa pandemi dengan mempertimbangkan aspek kebijakan internal rumah sakit, alur pelayanan ibu, kompetensi petugas, APD, sarana dan prasarana rumah sakit, sehingga diperlukan berbagai metode pendekatan dalam melakukan intervensi kebidanan dalam asuhan ibu hamil dengan konfirmasi COVID-19.Kata Kunci : Bidan, COVID-19, Maternal, Pengetahuan AbstractThe high incidence of maternal mortality is caused by problems in the quality of health services which are influenced by organizational, personal, and environmental factors. The Covid-19 pandemic in Indonesia continues and is likely to lead to a further increase in maternal mortality, so clinical leadership and assistance are needed. The method used in this community service program was providing training and assistance to midwives in preventing and handling maternal COVID cases in hospitals. This training succeeded in increasing the knowledge of midwives about handling maternal covid cases, prevention, and midwives’ leadership in maternal services by 35%. The implication of the results of this community service is the need for training on the knowledge and skills of midwives in handling maternal covid cases during the pandemic by considering aspects of hospital internal policies, maternal service flow, officer competence, PPE, hospital facilities and infrastructure, so we need various methods of approach in conducting midwifery interventions in the care of pregnant women with confirmed COVID-19.Keyword : COVID-19, Knowledge, Midwife, Maternal
Plasma Level of Umbilical Cord Hemeoxygenase-1 (HO-1) and Neonatal Outcome in Early Onset and Late Onset Severe Preeclampsia Muhammad Ilham Aldika Akbar; Indah Mayang Sari; Ernawati Ernawati; Aditiawarman Aditiawarman
Molecular and Cellular Biomedical Sciences Vol 3, No 1 (2019)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1056.632 KB) | DOI: 10.21705/mcbs.v3i1.57

Abstract

Background: Many studies had discovered that early onset severe preeclampsia (EO-PE) has worst maternal and neonatal outcome compared to late-onset type (LO-PE), related to its placental involvement. Severe preeclampsia was defined as newly onset severe hypertension developed after 20 weeks gestation in previously normal blood pressure women, with coexistence of proteinuria, or maternal organ or uteroplacental dysfunction. Hemeoxygenase-1 (HO-1) is an enzyme with multiple effect which is protective to pregnancy.Materials and Methods: The total study subjects were 40 pregnant women consisted of 10 EO-PE, 10 normal early onset pregnancy (EO-NP), 10 LO-PE, and 10 normal late onset pregnancy (LO-NP). As much as 5 cc of plasma from umbilical cord was taken as soon as the baby was born, and the HO-1 level was examined by enzyme-linked immunosorbent assay (ELISA). The primary outcome were umbilical cord HO-1 level and neonatal composite morbidity (low Apgar score, low birthweight, length of stay >5 day, respiratory distress syndrome, jaundice and neonatal death).Results: The plasma level of HO-1 in EO-PE subjects were lower than EO-NP (0.96±0.37 ng/mL vs. 2.43±0.58 ng/mL, p<0.001). There were no significant differences in the level of HO-1 in LO-PE and LO-NP (2.18±1.07 ng/mL vs. 3.02±0.64 ng/mL, p=0.277). Plasma level of umbilical cord HO-1 of EO-PE patients was lower compared to LO-PE (0.96±0.37 ng/mL vs. 2.18±1.07 ng/mL, p=0.034). Neonatal outcome of EO-PE was worse than EO-NP (p=0.033), and LO-PE (p=0.003), while in LO-PE did not different with LO-NP (p=0.211).Conclusion: EO-PE is associated with lower plasma umbilical cord level of HO-1 and worse neonatal outcome compared to LO-PE. This indicating abnormal placental blood vessel development, placental ischemia in EO-PE, lead to reduced uteroplacental perfusion and significantly worse neonatal outcome compared to LO-PE.Keywords: severe preeclampsia, early onset preeclampsia, late onset preeclampsia, hemeoxygenase-1 
Co-Authors Aditiawarman Aditiawarman - Amelia Rahmah Kartika Amila Anasantrianisa Atika Atika Atika Atika Bayu Agung Sangkara Putra Budi Santoso BUDI UTOMO Ernawati Ernawati Ernawati Ernawati Fadhilah Rahmawati Faqihati Husna Hapsari Kinanti Haris Rasyid Ridho Indah Mayang Sari Indra Yuliati Intan Dewi Angia Sari Ivon Diah Wittiarika Izzati Dwi Lady Aqnes Kurniawati Lucyana Septia Pramita Made Chindy Dwiyanti Marheni Putri Martono Tri Utomo Monika Mongang Manuk Muhammad Ardian Cahya Laksana Nadira Zahra Maulidya Permana Nuzulul Azizah Ramdan Wulandari Pudji Lestari Pudji Lestari Pudji Lestari Pudji Lestari Rize Budi Amalia Umiastuti, Pirlina Widati Fatmaningrum Widati Fatmaningrum