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All Journal JURNAL WIDYA MEDIKA Majalah Obstetri dan Ginekologi Molecular and Cellular Biomedical Sciences (MCBS) Halaman Olahraga Nusantara : Jurnal Ilmu Keolahragaan JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga International Islamic Medical Journal INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL JKKI : Jurnal Kedokteran dan Kesehatan Indonesia

Aditiawarman -

Airlangga University

Author-ID : 2410124

Religion Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

Published : 12 Documents Claim Missing Document

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25(OH)D Inadequacy Has Different Pathway with VEGF in Increases the Risk of Severe Preeclampsia Hanifa Erlin Damayanti; Aditiawarman Aditiawarman
Majalah Obstetri dan Ginekologi Vol. 23 No. 2 (2015): Mei - Agustus 2015
Publisher : Universitas Airlangga

Objectives: To identify in vivo correlation between 25(OH)D and VEGF in severe preeclampsia.Materials and Methods: A case control, cross sectional study of 36 pregnant women which consist of 18 patients with preeclampsia and 18 patients as control with gestational age-matched. We perform 25(OH)D serum examination by chemiluminescent immunoassay (CLIA) and VEGF serum examination by sandwich ELISA to all patients.Results: All patients are in 25(OH)D insufficiency and deficiency state. Both maternal 25(OH)D and VEGF levels were inversely associated with the risk of preeclampsia (both P<0.05). There is no correlation between 25(OH)D serum level and VEGF serum level (P=0,629).Conclusion: Maternal vitamin D deficiency is associated with increased preeclampsia risk. However, our data do not support the hypothesis that the association between vitamin D deficiency and preeclampsia is mediated by impaired level of VEGF.

Comparison of serum soluble edoglin (sEng) level in eary onset preeclampsia, late onset preeclampsia and normal pregnant woman Aldika Akbar; Mita Herdiyantini; Aditiawarman Aditiawarman
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Objectives: This study aimed to compare the serum levels of soluble Endoglin (s-Eng) between early onset preeclampsia, late onset preeclampsia and normal pregnant women.Materials and Methods: This was an analytic observational study (Cross-Sectional) performed on 39 pregnant women with early-onset preeclampsia (EO-PE), late-onset preeclampsia (LO-PE), and normal pregnancy. The patients were consecutively chosen in Dr. Soetomo Hospital, Airlangga University Hospital and Dr. M. Soewandhi Hospital Surabaya in May-July 2016. The serum concentration of soluble Endoglin were collected by venous puncture taken from maternal circulation and measured by ELISA.Results: From this study, serum concentrations of soluble Endoglin was higher significantly on the early onset preeclampsia compared with late onset preeclampsia and normal pregnancy (47,65 ± 40,17 vs 13,46 ± 9,48 vs 6,11 ± 1,45 ng/mL; p=0.000). Conclusion: This study shows angiogenic imbalance was more prominent compared in early-onset than late-onset preeclampsia. This may be because the placental dysfunction, placental ischemia, which produce excessive anti angiogenic factors, whic later causing endothelial dysfunction was more related to early onset preeclampsia.

Profile of pregnant women with preeclampsia and its termination method Vebianti Permadi; Aditiawarman Aditiawarman; Pudji Lestari
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.10-16

HIGHLIGHTS 1. Pregnancy with preeclampsia in this study was mostly terminated by cesarean section. A small percentage was with vaginal delivery.2. Most preeclamptic mothers gave birth by cesarean section exhibited severe symptoms of preeclampsia, such as severe hypertension, severe proteinuria, and visual impairment. ABSTRACT Objectives: To determine the symptoms of pregnant women with preeclampsia through the method of pregnancy termination. Materials and Methods: This study used a cross-sectional method for descriptive analysis. The total sample included 75 pregnant women with preeclampsia. The sampling techniques was carried out with purposive sampling. This study used auxiliary data in medical records of preeclampsia mothers who gave birth at Taman Husada Regional Hospital, Bontang, Indonesia, in 2019. Results: The results showed that most preeclampsia mothers delivered by cesarean section (CS). Among mothers who gave birth by cesarean section, there were severe symptoms of preeclampsia, 74.14% had severe hypertension with systolic blood pressure of > 160 mmHg or diastolic blood pressure of > 110 mmHg. Those with severe proteinuria with urine protein > 2g/24 hours or > +2 were 82.76% and 60.35% of those complained visual impairment with blurred vision. Conclusion: These data indicated that most mothers with preeclampsia gave birth by cesarean section and exhibited severe symptoms of preeclampsia.

Co-Authors Abdullah N Aldika Akbar Aldika M. I Almira Maharani Aryananda R. A Chiquita Febby Pragitara Cininta N. I Dachlan E G Endyka Erye Frety Ernawati Ernawati Fariska Zata Amani Fitri Indah Pratiwi Gumilar K. E Hanifa Erlin Damayanti HERAWATI, LILIK Hermanto T. J I'tishom, Reny Indah Mayang Sari Izzati Dwi Martono Tri Utomo Mita Herdiyantini Mufidah Sheena Andani Prastini Muhammad Ilham Aldika Akbar Nabila Annisa Harum Ninik Darsini Noza Loviana Nurmaliatul Firdaus Prastiya Indra Gunawan Pudji Lestari Risa Etika, Risa Sulistyono A Vebianti Permadi Wahyul Anis Wardhana M. P Wicaksono B Widati Fatmaningrum

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