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All Journal Medical Laboratory Technology Journal Jurnal Skala Kesehatan Husada Mahakam: Jurnal Kesehatan Medika Kartika : Jurnal Kedokteran dan Kesehatan Jaringan Laboratorium Medis
Dinna Rakhmina
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Anemia dan Lama Konsumsi Obat Anti Tuberculosis Anny Thuraidah; Rima Agnes Widya Astuti; Dinna Rakhmina
Medical Laboratory Technology Journal Vol. 3 No. 2 (2017): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (841.815 KB) | DOI: 10.31964/mltj.v3i2.157

Abstract

Tuberculosis is an infectious disease due to Mycobacterium tuberculosis germ that can infect several organs, including the lungs, kidneys, and bones. The goal of treatment of tuberculosis is tuberculosis bacilli destroy quickly and prevent recurrence. First category treatment of tuberculosis is isoniazid, rifampin, streptomycin, ethambutol, and pyrazinamide. Although the most anti-tuberculosis drug is acceptable in therapy, but have potentially toxic effects hematologic reactions such as agranulocytosis, eosinophilia, thrombocytopenia, and anemia. This research aims to know the correlation between anti-tuberculosis drug consumption in pulmonary TB patients against anemia. Method of this research was Analytical Survey with a Cross-Sectional design. The average results of red blood cell count for 0 months 5,16 106/uL, 2 months 4,39 106/uL and 6 months 4,61 106/uL, haemoglobin levels for 0 month 15,17 g/dL, 2 months 12,73 g/dL and 6 months 13,28 g/dL as well as hematocrit value for 0 month 44,26 %, 2 months 38,24 % and 6 months 39,04 %. From Spearman statistics analytical was obtained significant of red blood cell count 0.004 < α (0.05), levels of hemoglobin 0.007 < α (0.05) and the value of hematocrit 0.015 < α (0.05), it was concluded there was correlation between long consumption of anti-tuberculosis drug with anemia and the value of the correlation coefficient count of red blood cells -0.531, levels of hemoglobin-0.479 as well as the value of hematocrit -0.440 means has the power correlations are medium. Further research is recommended to use different parameters such as the number of platelets, AST/ALT levels and should use the same patient sample or from 0 months up to 6 months
Immune Response to anti-HBs Antibodies in Health Workers Following Hepatitis B Vaccination Dinna Rakhmina; Wahdah Norsiah; Tini Elyn Herlina; Norhafizah Mulia Sari; Reza Pertiwi; Rizka Ariani; Sahri Rahman
Medical Laboratory Technology Journal Vol. 7 No. 2 (2021): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.363 KB) | DOI: 10.31964/mltj.v7i2.418

Abstract

According to Regulation No. 53 of 2015 of the Minister of Health of the Republic of Indonesia, a high risk of HBV infection in health workers is a problem that requires attention, and vaccination knowledge is critical to reducing these risk factors. Furthermore, because some people do not produce a sufficient antibody-forming (anti-HBs) response to HBsAg, testing for evidence of protective immunity against hepatitis B vaccination is required (Hepatitis B Surface Antigen). The purpose of the study was to determine the mapping of the characteristics of anti-HBs antibodies response after hepatitis B vaccination in health workers in terms of age, gender, ethnicity, smoking habits, obesity, vaccination frequency, last time of vaccination. Sixty vaccinated health workers were used to creating the research sample. Anti-HBs levels/titers in serum were measured using the Enzyme-Linked Immunosorbent Assay (ELISA) method, and a questionnaire was used to compile the data for this study. Age, gender, smoking, obesity, and vaccination dose were all used to map the outcomes of the anti-HBs antibody immune response study. Anti-HBs antibody response in health workers was graded as poor in 36 people (60%) and strong in 24 (40%). Regarding ethnic origin, lifestyle, obesity, and vaccination dose (frequency), there was no significant link between post-vaccination anti-HBs antibody response in health workers. In terms of age and gender, there is a strong association between post-vaccination anti-HBs antibody responses in health workers. Low antibody titers should be revaccinated to enhance anti-HBs titers, and health workers who smoke should quit because it reduces the levels of anti-HBs titers produced clinically.
Sputum Quality of The Anytime And Outset for Examination Acid-Resistance Bacilli Leka Lutpiatina; Wahidah Wahidah; Nurhilaliah Nurhilaliah; Dinna Rakhmina; Rifqoh Rifqoh
Medical Laboratory Technology Journal Vol. 4 No. 1 (2018): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (894.538 KB) | DOI: 10.31964/mltj.v4i1.183

Abstract

Diagnosis Tuberculosis (TB) can establish by microscopic examination of acid-resistant bacilli in the patient's sputum. Sputum quality greatly affects the diagnosis of TB, but the sputum collected by patients at community health centers sometimes does not meet the sputum quality requirements. The objective of this study was to assess the quality of sputum anytime and outset sputum on acid-resistant bacilli examination, from volume, color and viscosity parameters. The type of research used is descriptive observational. Respondents were suspected TB patients at the Marabahan and Aluh-aluh Public Health Centers of South Kalimantan province, Indonesia. Sputum samples taken were sputum anytime the first and outset sputum. The variables in this study are volume, color, and viscosity of sputum. The coloring of acid-resistant bacilli method Ziehl Nielsen. The results of the acid-resistant bacilli examination on sputum (86 specimens) found positive one (13%), positive three (2%), negative (85%). In morning sputum (86 specimens) found positive one (14%), positive three (2%), negative (84%). Sputum quality when with the good category as much as 36% and the quality of morning sputum with the good category as much as 55%. Conclusion Sputum outset has better quality than sputum at the anytime.
Gambaran Pemeriksaan Hbsag Pada Narapidana Di Lembaga Pemasyarakatan Perempuan Kelas IIA Martapura dewi ratih apriyanti; dinna rakhmina; wahdah norsiah
Jurnal Skala Kesehatan Vol 12 No 2 (2021): JURNAL SKALA KESEHATAN
Publisher : Politeknik Kementerian Kesehatan Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jsk.v12i2.327

Abstract

Hepatitis B adalah suatu penyakit hati yang disebabkan oleh virus hepatitis B, yang dapat menyebabkan peradangan hati akut atau menahun yang dapat berlanjut menjadi sirosis hati atau kanker hati. Untuk mengidentifikasi infeksi awal oleh virus hepatitis B dilakukan pemeriksaan HBsAg yang merupakan antigen permukaan yang ditemukan pada virus hepatitis B. Salah satu kelompok berisiko terinfeksi hepatitis B adalah narapidana. Narapidana di Lembaga Pemasyarakatan Perempuan Kelas IIA Martapura mempunyai risiko tinggi terhadap penyakit menular seperti hepatitis B dikarenakan kondisi Lapas yang melebihi kapasitas tampung serta tinggal dengan narapidana yang menderita hepatitis B pada Blok Anyelir. Tujuan penelitian ini untuk mengetahui gambaran HBsAg dan persentase narapidana yang terinfeksi hepatitis B di Lembaga Pemasyarakatan Perempuan Kelas IIA Martapura. Jenis penelitian ini adalah survei deskriptif. Populasi adalah narapidana yang tinggal di Blok Anyelir dengan teknik sampel berupa Accidental sampling sebanyak 26 orang. Sampel berupa serum yang diperiksa dengan metode Immunochromatographic Assay (ICA). Berdasarkan hasil penelitian yang telah dilakukan didapatkan persentase HBsAg non reaktif (-) sebanyak 100% dan HBsAg positif 0%. Bagi peneliti selanjutnya disarankan untuk melakukan penelitian dengan populasi sampel yang lebih banyak dan diharapkan dapat melanjutkan dengan mendeteksi anti-HBsAg. Keyword : Narapidana; Hepatitis B; Immunochromatographic assay
Uji Efektivitas Air Perasan Daun Jeruk Limau Kuit ( Citrus hystrix ) Sebagai Insektisida Nabati Terhadap Mortalitas Kutu Rambut Pediculus humanus capitis Secara In Vitro Nidha Pusvita; Anny Thuraidah; Rifqoh Rifqoh; Dinna Rakhmina
Jaringan Laboratorium Medis Vol 4, No 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8579

Abstract

Lemongrass leaves are a typical plant of South Kalimantan which contain anti-insecticide, namely secondary metabolites such as alkaloids, saponins, tannins, steroids and triterpenoids. Pediculosis is a disease caused by a tick infection which is still neglected and becomes a health problem. One way to get rid of head lice is to use natural ingredients that contain anti-insecticide substances. This study aims to examine the possibility of using natural ingredients in lime leaves as vegetable insecticides against head lice mortality. The research method used is experimental, with a research design that is a post-test only control group, which measures and compares the mortality variable of Pediculus humanus capitis after being treated with lime leaf juice with concentrations of 10%, 30%, 60%, 100% during 1, 6, 12 and 24 hours and compared them with the negative control group with aquadest and the positive control with pemethrin. The sample of this study was lime leaf extract which was extracted by the method of squeezing using water. From the results of the study obtained the highest percentage of death at 12 and 24 hours with 100% mortality at a concentration of 100%. Based on the results of statistical tests using mortality observation data, the LC99 values were obtained within 1 hour (197.678%), 6 hours (126.055%), 12 hours (89.847%), and 24 hours (60.758%). Based on the results of the analysis of the data obtained, it can be concluded that there is effectiveness of lime leaf juice (Citrus hystrix) on the mortality of head lice (Pediculus humanus capitis) in vitro. Then the juice of lime leaves can be used as an alternative to getting rid of head lice with natural ingredients.
PROFIL ANTI-HBS PADA MAHASISWA TEKNOLOGI LABORATORIUM MEDIS POLTEKKES KEMENKES BANJARMASIN Dinna Rakhmina; Aini Luthfiah Hayati; Tini Elyn Herlina
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 5 No 3 (2022): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hepatitis B adalah infeksi yang disebabkan oleh virus Hepatitis B dan menyerang jaringan hati. Virus Hepatitis B dapat menular melalui darah dan cairan tubuh penderita. Infeksi Hepatitis B dapat dicegah dengan melakukan vaksinasi. Kekebalan tubuh terhadap infeksi virus Hepatitis B ditandai dengan adanya kandungan Anti-HBs. Anti-HBs merupakan antibodi protektif terhadap infeksi virus Hepatitis B. Kadar protektif Anti-HBs terhadap infeksi virus Hepatitis B sebesar ≥10 mIU/mL. Penelitian ini bertujuan untuk mengetahui profil anti-HBs pada mahasiswa Teknologi Laboratorium Medis Poltekkes Kemenkes Banjarmasin. Metode penelitian menggunakan survei deskriptif dengan rancangan cross sectional. Teknik penelitian yang digunakan yaitu purposive sampling. Populasi penelitian ini adalah mahasiswa Teknologi Laboratorium Medis, dengan jumlah sampel penelitian sebanyak 41 responden. Anti-HBs dalam darah dideteksi menggunakan rapid test HBsAb. Hasil penelitian menunjukkan pada 19 mahasiswa yang telah melakukan vaksinasi didapatkan hasil pemeriksaan Anti-HBs sebanyak 17 orang positif dan 2 orang negatif. Sedangkan, pada 22 mahasiswa yang belum melakukan vaksinasi didapatkan hasil pemeriksaan anti-HBs negatif pada seluruh responden. Sehingga diketahui bahwa antibodi anti-HBs pada mahasiswa muncul karena vaksinasi. Bagi penelitian selanjutnya disarankan menghitung titer anti-HBs kuantitatif menggunakan metode ELISA pada responden yang telah melengkapi dosis vaksinasi. DOI : 10.35990/mk.v5n3.p265-274
KARAKTERISTIK DAN PEMERIKSAAN RAPID TES ANTIBODI COVID-19 PADA IBU HAMIL DI PUSKESMAS WILAYAH MARTAPURA Dinna Rakhmina; Aina Nurvita Sari; Ratih Dewi Dwiyanti
Husada Mahakam Vol 11 No 2 (2021): Nopember 2021
Publisher : Poltekkes Kemenkes Kalimantan Timur (URL: http://poltekkes-kaltim.ac.id/)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35963/hmjk.v11i2.258

Abstract

Wuhan, China was the place where the first cases of Covid-19 were found, and 118 pregnant women with COVID-19 were identified from 50 hospitals throughout the city of Wuhan from December 2019 – March 2020. The purpose of this study was to find out the description of the Covid-19 examination in pregnant women at Puskesmas Martapura City. A descriptive survey is conducted using a cross-sectional design. All pregnant women in their third trimester who had a rapid test for Covid-19 antibodies performed at the Puskesmas Martapura City and samples taken utilizing a full sampling approach were included in this study. The study's conclusions were mostly based on their age (20-35 years) 14 individuals (70%), senior high school 12 people (60%), housewives 18 people (90%), and knowledge level (100%). The results showed that 131 people were reactive and 957 were non-reactive in the antibody rapid test examination for pregnant women in their third trimester from June 2020 to March 2021. According to the findings, 12.04% of pregnant women in their third trimester are reactive, whereas 87.96% are non-reactive. Suggestions to the public on how to better understand clinical symptoms, mechanisms of transmission, and Covid-19 prevention efforts in order to encourage good lifestyle choices. This research can be continued by observing the severity of Covid-19 symptoms in pregnant women who are infected and the effect of pregnant women infected with Covid-19 on babies born. Keywords: Covid-19, Antibody rapid test, Pregnant woman
PROFIL ANTIBODI ANTI-SARS-CoV-2 S1RBD (IgG) PASCA VAKSINASI COVID-19 PADA CIVITAS AKADEMIKA POLTEKKES KEMENKES BANJARMASIN Dinna Rakhmina; Linda Yuliana
Husada Mahakam Vol 12 No 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Kalimantan Timur (URL: http://poltekkes-kaltim.ac.id/)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35963/hmjk.v12i2.350

Abstract

The first vaccination program started in early December 2020 and as of February 15, 2021, 175.3 million doses of the vaccine had been administered. Although the clinical trial data for the Covid-19 vaccine meets the WHO standard requirements, concrete evidence relating to the efficacy and effectiveness of the vaccine still needs to be researched and developed further. Therefore, there is still a lack of research and publications on the development of the Covid-19 vaccine in Indonesia, so this research will raise the issue of the extent to which factors of age, gender, ethnicity, history of Covid-19 infection, and vaccination dose affect the formation of antibodies after Covid vaccination. -19 in the Banjarmasin Ministry of Health Poltekkes academic community and the ability to protect against Covid-19 infection. The research is an analytical survey with a cross sectional design and as a sample is the academic community of Poltekkes Kemenkes Banjarmasin who have been vaccinated against Covid-19 stages I, II and III (booster). The method of determining antibody levels uses the ELISA principle plus supporting data through a questionnaire to explore data on the characteristics of the respondents. The results of measurements with ELISA obtained levels of Anti-SARS-Cov-2 S1RBD IgG antibodies which were grouped into 3 categories, namely: low (< 5 IU/mL) 3%, moderate (5 – 99 IU/mL) 8%, high (> 99 IU/mL) 89% and there is a significant value in terms of vaccination dose where the dose up to stage III (booster) is directly proportional to the increase in the level of antibodies formed. Keywords: Covid-19 Vaccination, Antibody Level, Elisa Method
Co-Authors Aina Nurvita Sari Aini Luthfiah Hayati Anny Thuraidah dewi ratih apriyanti leka lutpiatina, leka Linda Yuliana Muhammad Rivai Nidha Pusvita Norhafizah Mulia Sari Nurhilaliah Nurhilaliah Ratih Dewi Dwiyanti Rifqoh Rifqoh Rima Agnes Widya Astuti Rizka Ariani Sahri Rahman Tini Elyn Herlina wahdah norsiah Wahidah Wahidah