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Tingkat Pengetahuan Siswi SMA Muhammadiyah I Palangka Raya tentang Penyakit Kanker Payudara Syahrida Dian Ardhany; Guntur Satrio Pratomo; Siti Jamilah
Jurnal Surya Medika (JSM) Vol 4 No 1 (2018): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Breast cancer is the number 2 cause of death in the world. The incidence of breast cancer is mostly in women. Student knowledge is expected to reduce the impact of breast cancer. The purpose of this study is to know the level of knowledge of Muhammadiyah I senior high school students of Palangka Raya about breast cancer. Methode of this research was the descriptive method by using a questionnaire. The results obtained from 48 female students the percentage of correct answer was 69.99%. It can be concluded the level of knowledge of Muhammadiyah I senior high school students of Palangka Raya included in the category enough knowledge.

Tingkat Pengetahuan Masyarakat Desa Anjir Mambulau Tengah terhadap Penggunaan Antibiotik Guntur Satrio Pratomo; Nuria Ayu Dewi
Jurnal Surya Medika (JSM) Vol 4 No 1 (2018): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Medicine is all substances such as chemical, animal or vegetative in a possible dose that could heal, assuage or prevent the disease and its symptoms. Infectious disease is still the most of health society problem, especially in developing country. Antibiotics are chemical substances generated by microorganisms which have the ability to obstruct the growth or eliminate another microorganism. Antibiotics are the most widely used medicine for infectious which caused by bacteria. The accurate recipe and good consumption of antibiotics use will give well beneficial and effective for the patient. Otherwise, using antibiotics which not suitable for the instruction will conduct the decrease of the medicine function itself (antibiotics resistance), and could make new disease caused by the wrong application. Anjir Mambulau village is located in Province of Central Kalimantan, particularly the part of Kapuas Hilir district, Kapuas. These villagers mostly obtain the medicines from a small shop and consume it based on the experiences and family suggestions only. The purpose of this research is to know the knowledge level of Anjir Mambulau villagers about antibiotics use, using the descriptive method with the valid questionnaire, to the sample of the village's population by purposive sampling technique, the questionnaire contains any questions with semi-open way which made by the researchers that should be answered by the respondent. This research sourced from 309 respondents results that 35,5% villagers of AnjirMambulau have not the cognize of using antibiotics.

Sosialisasi Gerakan Keluarga Sadar Obat (GKSO) di Desa Tabore Kecamatan Mantangai Kabupaten Kapuas Kalimantan Tengah Guntur Satrio Pratomo; Dewi Sari Mulia; Nurul Qamariah
Jurnal Surya Medika (JSM) Vol 2 No 1 (2016): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Gerakan Keluarga Sadar Obat (GKSO) adalah program yang dicanangkan oleh Ikatan Apotoker Indonesia (IAI) yang merupakan upaya bersama untuk meningkatkan pemahaman masyarakat terhadap obat melalui sosialisasi DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang) obat dengan benar. Metode pelaksanaan kegiatan adalah dengan menggunakan metode penyuluhan. Kegiatan yang dilakukan adalah dengan memberikan penyuluhan kepada masyarakat desa Tabore. Materi yang disampaikan adalah mengenai Gerakan Keluarga Sadar Obat dengan berfokus pada DAGUPIPISIBU (Dapatkan, Gunakan, Pilih-pilih, Simpan, dan Buang) obat dengan benar, meliputi: (1) Agar obat memberikan manfaat dan keamanan bagi anda ingatlah DAGUPIPISIBU; (2) Dapatkan obat dengan benar gunakan obat dengan benar buang obat dengan benar simpan obat dengan benar; (3) Dapatkan obat dengan benar tempat pelayanan obat resmi adalah Apotik; (4) Konsultasi dengan apoteker di Apotik untuk mendapatkan obat yang aman, bermanfaat dan berkualitas; (5) Konsultasi dengan Apoteker di Apotik agar dapat menggunakan obat dengan benar; (6) Konsultasi dengan Apoteker di Apotik karena setiap obat memerlukan kondisi penyimpanan yang berbeda dan (7) Konsultasi dengan Apoteker di Apotik agar dapat membuang obat dengan benar. Kegiatan ini merupakan salah satu upaya dalam meningkatkan ketepatan Swamedikasi masyarakat yang selama ini dilakukan tanpa pengawasan sebagai salah satu upaya untuk meningkatkan derajat kesehatan masyarakat Indonesia khususnya masyarakat yang berada di daerah terpencil.

Pengaruh Jenis Media dengan Hormon Tumbuh NAA-BAP terhadap Pertumbuhan dan Kandungan Flavonoid Kalus Daun Echinaceae purpurea (L.) Moench Guntur Satrio Pratomo
Jurnal Surya Medika (JSM) Vol 1 No 2 (2016): Jurnal Surya Medika
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Echinaceae purpurea (L.) Moench merupakan tanaman obat yang mempunyai khasiat salah satunya imunomodulator dan imunostimulan. Tanaman ini mengandung metabolit sekunder salah satunya yaitu falvonoid. Penelitian ini bertujuan untuk mengetahui kemampuan media dalam menginduksi kalus dan mempengaruhi kandungan flavonoid dalam kalus daun E. purpurea (L.) Moench. Eksplan adalah daun E. purpurea (L.) Moench yang segar, sehat, dan tidak terlalu tua. Sterilisasi eksplan dilakukan dengan Dithane M-45 2 %, dengan penambahan Tween 80, Agrept 20/WP 2 % dengan penambahan Tween 80, alkohol 70 %, dan Bayclin® 10 %. Penanaman eksplan dilakukan dengan menggunakan media MS, ½ MS, dan Gamborg dengan penambahan kombinasi zat pengatur tumbuh NAA dan BAP masing-masing konsentrasi 1 ppm. Evaluasi kalus dilakukan terhadap prosentase keberhasilan pembentukan, waktu induksi, dan rata-rata berat kalus. Analisa flavonoid dalam kalus dilakukan secara kualitatif dengan reaksi warna, tes Wilstater Cyanidin, Kromatografi kertas , dan Kromatografi Lapis Tipis, serta semikuantitatif dengan KLT-Densitometri Hasil penelitian menujnukkan bahwa jenis media mempengaruhi keberhasilan pertumbuhan kalus dan kandungan flavonoid kalus daun E. purpurea (L.) Moench. Media Gamborg berpengaruh paling baik dalam menginduksi kalus sedangkan media ½ MS berpengaruh paling baik terhadap kandungan flavonoid di banding jenis media lain.

Uji Potensi Daya Hambat Ekstrak Metanol Biji Jintan Hitam (Nigella Sativa L.) Terhadap Bakteri Streptococcus Guntur Satrio Pratomo; Nurul Chusna; Muhammad Priyadi
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1615

One of the plants that are often used as medicinal plants is Black Seed, Black Seed is a medicinal plant known in Indonesia by the name of black cumin. Black cumin seeds and essential oils (Nigella sativa L.) have been widely used in traditional medicine. Many studies have proven the effects of Nigella sativa extract. In various studies, black cumin seed oil shows efficacy as an anti-cancer, anti-free radical and immunomodulator, analgesic, antimicrobial, anti-inflammatory, a spasmolytic, bronchodilator, hepatoprotective, and anti-hypertensive Advanced chemical analysis found that Black Seed contains carotene that is converted into vitamin A by heart. The purpose of this study was to determine the potential inhibition of methanol extract of black cumin seeds (Nigella Sativa L.) against Streptococcus. This research uses a quantitative approach with an experimental method. This research was conducted in the Pharmacognition and Microbiology Laboratory of the Faculty of Health Sciences, Muhammadiyah University, Palangkaraya. The sample used was a sample of plant material, namely Black Cumin Seed (Nigella sativa L) which had been dried and pollinated and then extracted and then tested against bacteria. The results of testing the antibacterial activity showed that from low concentration to high concentration the diameter of the resulting inhibition showed that the activity could inhibit the bacteria streptococcus mutants. The highest inhibition at a concentration of 6% is 0.83 mm and the lowest concentration at a concentration of 3% against Streptococcus mutants.

Identifikasi Sakarin pada Es Kelapa Muda yang Dijual di Pasar Rajawali Kota Palangka Raya Guntur Satrio Pratomo
Jurnal Surya Medika (JSM) Vol 6 No 2 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i2.2131

Saccharin is a class of food additives permitted by Indonesia Republic Minister of Health Regulation No. 33 of 2012 for use in drinks, but if consumed in excess can cause harmful effects on health such as causing allergies and bladder cancer. The purpose of this study was to determine the presence of saccharin in coconut ice drinks in Pasar Rajawali Kota Palangka Raya. The sample used was 5 samples and the sampling technique was saturated sampling. Saccharin examination is done qualitatively using the resorcinol method. The results of research that has been done show that all samples of coconut ice drinks that have been tested negatively contain saccharin sweeteners.

Pharmacophore Optimization Of Berberine As HER2 Inhibitor Mohammad Rizki Fadhil Pratama; Guntur Satrio Pratomo
Jurnal Farmasi Indonesia Vol 14 No 2 (2017): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Previous research has shown that berberine, an alkaloid found in several plants such as akar kuning (Arcangelisia flava) shows the potential for inhibition of Human epidermal receptor-2 (HER2). Pharmacophore modification on the berberine was predicted could increase the affinity of berberine derivatives against HER2. The present study aims to determine the main pharmacophore of berberine with the highest influence towards berberine affinity against HER2. Molecular docking was performed on several modified pharmacophore of berberine against HER2. The docking results show that O atom at position number 23 has the most important influence on the berberine affinity towards HER2, where modification of O atom resulting in a decrease of berberine affinity. The highest affinity showed by derivate berberine-6 with the free energy of binding score and dissociation constant -10.80 kcal/mol and 12.17 nM, respectively. In contrast with other berberine derivatives, the berberine-6 derivate does not interact with the amino acid threonine at position 862. It provides a prediction that interaction of that amino acid potentially decrease the berberine activity towards active site of HER2. Further, derivate berberine-6 could be developed into HER2 inhibitor and should be potential to be developed as HER2-positive breast cancer therapy.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN RAMBUSA DAN DAUN KARAMUNTING TERHADAP Streptococcus mutans Muhammad Priyadi; Nurul Chusna; Guntur Satrio Pratomo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.875

Empirically, many natural ingredients have been used in preventive care for the treatment of dental and oral disorders. Chronic conditions on the teeth with the appearance of plaque and tooth decay are referred to as dental caries which are characterized by toothache and also digestive disorders. Streptococcus mutans is known as the bacteria that most often causes dental caries. Karamunting and rambusa plants have enough potential as antibacterials because there have been many studies that have shown their potential as antibacterial activities. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of karamunting leaves and rambusa leaves against Streptococcus mutans. Antibacterial activity test using well diffusion method by measuring the diameter of the inhibition zone. The results showed that the ethyl acetate extract of karamunting leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.6 mm, 4.1 mm, 0 mm, 0 mm, 0 mm, respectively while rambusa leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.4 mm, 8.7mm, 9.4 mm, 5.3mm and 8.8mm respectively. The ethyl acetate extract of karamunting and rambusa leaves is known to have weak antibacterial activity in the resistant category.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN RAMBUSA DAN DAUN KARAMUNTING TERHADAP Streptococcus mutans Muhammad Priyadi; Nurul Chusna; Guntur Satrio Pratomo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.875

Empirically, many natural ingredients have been used in preventive care for the treatment of dental and oral disorders. Chronic conditions on the teeth with the appearance of plaque and tooth decay are referred to as dental caries which are characterized by toothache and also digestive disorders. Streptococcus mutans is known as the bacteria that most often causes dental caries. Karamunting and rambusa plants have enough potential as antibacterials because there have been many studies that have shown their potential as antibacterial activities. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of karamunting leaves and rambusa leaves against Streptococcus mutans. Antibacterial activity test using well diffusion method by measuring the diameter of the inhibition zone. The results showed that the ethyl acetate extract of karamunting leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.6 mm, 4.1 mm, 0 mm, 0 mm, 0 mm, respectively while rambusa leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.4 mm, 8.7mm, 9.4 mm, 5.3mm and 8.8mm respectively. The ethyl acetate extract of karamunting and rambusa leaves is known to have weak antibacterial activity in the resistant category.

Sosialisasi Peran dan Aksi Muhammadiyah Disaster Management Center (MMDC) Pada Penanggulangan Bencana Hidrometeorologis di Kota Palangka Raya Rita Rahmaniati; Sari Marlina; Guntur Satrio Pratomo; Bulkani
I-Com: Indonesian Community Journal Vol 3 No 2 (2023): I-Com: Indonesian Community Journal (Juni 2023)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Kelurahan Bereng Bengkel berpotensi mengalami banjir yang cukup tinggi. Kegiatan pengabdian masyarakat ini dimaksudkan untuk: 1) mensosialisasikan keberadaan Tim MDMC Kalimantan Tengah, 2) memberikan pemahaman tentang Mitigasi bencana Hidrometeorologis, 3) membentuk Satgas MDMC di kelurahan Bereng Bengkel, dan 4) Memberikan aksi nyata MDMC berupa layanan pengobatan gratis bagi warga kelurahan Bereng Bengkel. Metode pelaksanaan melalui ceramah, diskusi, dan aksi. Sasaran peserta adalah warga desa, perangkat desa, dan mahasiswa relawan UMPR. Total peserta yang mengikuti kegiatan pengabdian adalah 50 peserta. Berdasarkan evaluasi, kegiatan pengabdian ini peserta telah memiliki pemahaman sangat baik, target terbentuknya satgas atau kader MDMC di Kelurahan Bereng Bengkel tercapai dan aksi nyata MDMC layanan kesehatan gratis terlaksana dengan sukses dan lancar. Pada dasarnya bimbingan MDMC kota Palangkaraya dan Lurah Bereng Bengkel diperlukan untuk menyusun program kerja dan monitoring sehingga aksi MDMC di masyarakat dapat di laksanakan secara berkelanjutan. Selain itu harapannya MDMC lebih dikenal masyarakat luas. Fashtabiqul Khoirat.

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