Nurlindah Hamrun
Department Of Oral Biology, Faculty Of Dentistry, University Of Hasanuddin, Makassar, Indonesia

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HUBUNGAN POLIMORFISME GEN VITAMIN D RESEPTOR DENGAN PERIODONTITIS KRONIS: POLYMORPHISM OF VITAMIN D RECEPTOR GENE IS ASSOCIATED WITH CHRONIC PERIODONTITIS Nurlindah Hamrun
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.304 KB) | DOI: 10.32734/dentika.v16i2.1826

Abstract

Chronic periodontitis is caused by enhanced resorption of the alveolar bone supporting the teeth and is associated with intraoral inflammation after infection with certain bacteria. Genetic polymorphisms in vitamin D receptor (VDR) gene are associated with bone homeostasis and immunological reaction. The aim of this study was to determine whether polymorphism in VDR gene exons is associated with the incidence of chronic periodontitis. A case-controll study was performed on a group of 162 subjects whose ages ranged from 25 to 60 years, were divided into two groups : 81 healthy individuals (control group) and 81 subjects with chronic periodontitis. The polymorphism in the VDR gene was analyzed by polymerase chain reaction, followed by TaqI restriction endonuclease digestion. The result showed that the polymorphism in the vitamin D receptor gene was found in chronic periodontitis with TT genotype (86.4%), Tt genotype (12.4%), and tt genotype (1.2%). This study also determines taqI polymorphism of the VDR gene is associated with the incidence of chronic periodontitis case (OR 12.57; CI: 1.6-99.8). In conclusion, polymorphism of the vitamin D receptor gene is associated with the incidence of chronic periodontitis (OR 12.57).
Antioxidant activity of red algae extract (rhodophyta) eucheuma spinosum with DPPH (2,2-diphenyl-1- picrylhydrazyl) method Hamrun, Nurlindah; Djamaluddin, Nursyamsi; Dahri, Irvina NA.
Journal of Dentomaxillofacial Science Vol 7, No 1 (2022): (Available online: 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v7i1.1309

Abstract

Objective: To determine the results of the antioxidant concentration of red algae extract (Rhodophyta) Eucheuema Spinosum.Material and Methods: The type of research method used in this study is an experimental laboratory.Results: Antioxidant research results of red algae extract (Rhodophyta) Eucheuema Spinosum dry extract of ethanol fraction using DPPH (2,2-diphenyl-1- picrylhydrazyl) method had IC50 values of 702,387 µg / mL and Vitamin C IC50 of 2,588 µg / mL. Antioxidant levels of Vitamin C are more substantial.Conclusion: Antioxidants of red algae extract (Rhodophyta) Eucheuema Spinosum dry extract ethanol fraction IC50 value 702,387 µg / mL 
PELATIHAN PEMBUATAN PAPAN IKLAN DOT-MATRIKS BERBASIS MIKROKONTROLER DI SMKN 1 WAJO A. Arifin; Ida Laila; Muqoil Darussalam; Nurlindah Hamrun; Dahlang Tahir; Syamsir Dewang
Panrita Abdi - Jurnal Pengabdian pada Masyarakat Vol. 5 No. 3 (2021): Jurnal Panrita Abdi - Juli 2021
Publisher : LP2M Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/pa.v5i3.11254

Abstract

Technological development in the manufacture of microcontroller-based dot-matrix billboards carried out in the form of counseling and training for students at Wajo 1 State Vocational High School (SMK). The implementation of this training aims to increase the insight, knowledge, and skills of vocational school students, which are an educational level that must have different knowledge from the level of education in general. The method of implementing this activity includes site observation, preparation, counseling, and provision of materials related to physics and energy, entrepreneurship, optoelectronic technology, as well as the implementation of training on making Arduino microcontroller-based dot-matrix billboards and evaluating the training implementation. The result of this activity is an increase in the knowledge and insight of students in terms of making a series of dot-matrix billboards using electronic components, understanding program code, running the Arduino Integrated Development Environment (IDE) program, conducting simulations on circuits using the Arduino microcontroller and students have successfully demonstrated and run the running text panel that was created using an Android smartphone. --- Pengembangan teknologi dalam pembuatan papan iklan dot-matriks berbasis mikrokontroler yang dilakukan dalam bentuk penyuluhan dan pelatihan kepada siswa-siswi di Sekolah Menengah Kejuruan (SMK) Negeri 1 Wajo . Pelaksanaan pelatihan ini bertujuan untuk meningkatkan wawasan, pengetahuan dan keterampilan siswa-siswi SMK yang merupakan tingkat pendidikan yang harus memiliki pengetahuan yang berbeda dari tingkat pendidikan pada umumnya. Metode pelaksanaan kegiatan ini meliputi peninjauan lokasi, persiapan, penyuluhan dan pemberian materi terkait fisika dan energi, kewirausahaan, teknologi opto-elektronika, serta pelaksanaan pelatihan pembuatan papan iklan dot-matriks berbasis mikrokontroler arduino dan evaluasi pelaksanaan pelatihan. Hasil dari kegiatan ini adalah adanya peningkatkan pengetahuan serta wawasan siswa dalam hal pembuatan rangkaian papan iklan dot-matriks menggunakan komponen elektronika, memahami kode program, menjalankan program arduino Integrated Developement Environment (IDE), melakukan simulasi pada rangkaian menggunakan mikrokontroler arduino serta siswa telah berhasil mendemonstrasikan dan menjalankan panel running text yang telah dibuat dengan menggunakan smartphone android.  
Measuring sodium alginate content of brown algae species padina sp. as the basic matter for making dental impression material (irreversible hydrocolloid impression material) Nurlindah Hamrun; Suci A. Rachman
Journal of Dentomaxillofacial Science Vol. 1 No. 2 (2016): (Available online: 1 August 2016)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v1i2.11

Abstract

One of the most important procedures in denture fabrication and orthodontic treatment is molding the patient’s detail oral cavity to determine the treatment planning. This procedure was done by using alginate impression material or irreversible hydrocolloid in which the basic material is sodium alginate imported from abroad because it is extracted from brown algae which its habitat is not in Indonesia so that it is causes the impression material is relatively expensive roomates is impact to high cost of dental treatment. Indonesia as the archipelago country has availability of abundant brown algae Padina sp. Especially in Puntondo-Punaga seashore, South Sulawesi, but it has not Cultivate yet by the local society because it is never discovered by alginate industry so it is just grow wild and its potency is useless. This experiment identified the purposes of how much sodium alginate is produced from Padina Sp. Extraction as the basic matter of irreversible hydrocolloid. The design of this study is experimental design with one shot case study method. In early stage research, extraction of alginate in the form of sodium alginate. After that, they are weighted by using analytical weight in milligrams (mg) unit. Then, it is compare with the standard sodium alginate to observe the similarity of molecules by using FTIR (Fourier Transform Infra Red) device. Data were Analyzed using mean differences. Based on Padina extracted, produced 12.86 g of sodium alginate content or 28.4% from the cleaning algae was used roomates total weight is 45 g. Based on FTIR test, showed that sodium alginate is extracted similar to the standard sodium alginate with the found of hydroxyl, carboxylic acid, ether group and the which is the composer of sodium alginate. In conclusion, from both of infra red spectrum pattern, it was observed unsignificant difference. Extracted sodium alginate Padina is same with the standard sodium alginate and it has 12.86 g content. 
Perbandingan status gizi dan karies gigi pada murid SD Islam Athirah dan SD Bangkala III Makassar Nurlindah Hamrun; Mughny Rathi
Journal of Dentomaxillofacial Science Vol. 8 No. 1 (2009): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v8i1.209

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Economic status has an impact in life aspect, including nutrition status, caries, andoral hygiene. The aim of this study was to compare the nutritional status, dentalcaries and oral hygiene of Islam Athirah elementary school representing higheconomic status and Bangkala III elementary school, representing low economicstatus. Samples were 120 children of aged 10-11 years. Study design was crosssectional study. The criteria of school chosen, was based on annual tuition fee,contribution fee, entrance school fee, and the presence of school operational aid(Dana BOS). Nutrition status was accessed using Z-score, dental caries using def-tindex, and oral hygiene status accessed using OHI-S (DI-S and CI-S). Data of eatinghabitual, type of food, education and occupation of parents, frequency and method oftooth brushing were obtained from questionnaire. The results of this study showed nosignificant difference of nutritional status and oral hygiene status for both schools(Mann-Whitney, p = 0.281 and 0.936), whereas significant difference was found fordental caries status between Islam Athirah and and Bangkala III elementary school(p=0.01).
Ukuran mesiodistal dan servikoinsisal gigi insisivus sentralis suku Bugis, Makassar, dan Toraja tidak menunjukkan perbedaan yang bermakna Size of mesiodistal and cervicoincisal maxillary central incisors between Buginese, Makassarese, and Torajanese showed no significant difference Irene Edith Rieuwpassa; Nurlindah Hamrun; Fitrian Riksavianti
Journal of Dentomaxillofacial Science Vol. 12 No. 1 (2013): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v12i1.339

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Every tribe and race has size of tooth mesiodistal and cervicoincisal different from each other. The most obviousdifference is the size of the teeth between female and male. This study aimed to determine differences in size ofmesiodistal and cervicoincisal maxillary central incisors between male and female of Buginese, Makassarese andTorajanese. The sample consisted of 30 Buginese, 30 Makassarese, and 30 Torajanese aged frem 18-25 years-old.After impression of the upper and lower jaw was taken, and size of mesiodistal and cervicoincisal tooth weremeasured. After the data were analyzed by t-test and ANOVA test, it appears that males have a larger size thanfemales. Makassarese has the longest mesiodistal size (8.41 mm), Buginese has the longest cervicoincisal size (9.83mm), whereas Torajanese has the smallest size of mesiodistal and cervicoincisal among the other tribes. It was concluded that the average sizes of mesiodistal and cervicoincisal of maxillary central incisors showed no significantdifference. While there are significant differences in the average size of the mesiodistal and cervicoincisal maxillarycentral incisors between the males and females, and based on tribe lines.
Ekstrak buah kaktus pir berduri menghambat pertumbuhan Staphylococcus aureus, Streptococcus mutans, dan Candida albicans Extract of cactus prickly pear inhibits the growing of Staphylococcus aureus, Streptococcus mutans, and Candida albicans Irene Edith Rieuwpassa; Nurlindah Hamrun; St. Rahma Lukman; Reski Y. S; Soelistia Ramadhani
Journal of Dentomaxillofacial Science Vol. 12 No. 3 (2013): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v12i3.367

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The study aimed to determine the effect of prickly pear cactus extract in inhibiting the growth of Staphylococcusaureus, Streptococcus mutans and Candida albicans. The laboratory experimental study using diffusion method. Theconcentration of the prickly pear cactus fruit extract used was 25%, 50%, 75%, 100%, whereas bacterial samplesderived from the laboratory of Microbiology, Faculty of Medicine, University of Hasanuddin. The observation ofseveral concentrations showed a decrease in the number of colonies contained S.aureus, S.mutans, C.albicanssignificant with increasing concentrations of the prickly pear cactus fruit extract. From these observations, thelargest inhibitory concentration present in a concentration of 100%. The conclusion is the fruit of the prickly pearcactus extract can inhibit the growth of S.aureus, S.mutans, and C.albicans. The higher the concentration of theextract, the more reduced the growth of S.aureus colonies, S.mutans, and C.albicans and vice versa.
Physical characteristics test (water content and viscosity) of extraction sodium alginate brown algae (phaeophyta) species padina sp. as basic material for production dental impression material Nurlindah Hamrun; Bahruddin Thalib; Dahlang Tahir; Syaharuddin Kasim; Ahmad F. Nugraha
Journal of Dentomaxillofacial Science Vol. 3 No. 2 (2018): (Available online: 1 August 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v3i2.625

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Objective: This research aims to explore the potential of brown algae species padina sp. as a dental impression material by examining the physical characteristics of the sodium alginate extraction of brown algae species padina sp.Material and Methods: This research is a quasi-experimental with one-shot case study design. Samples are brown algae species padina sp. from Punaga and Puntondo beach in South Sulawesi. Brown algae species padina sp. is extracted to obtain sodium alginate and further tested for physical characteristics including viscosity test and water content.Results: The extraction of brown algae species padina sp. resulted in 250 grams (25%) of brown powdered sodium alginate that smelled fishy. Physical characteristic tests revealed the water content of sodium alginate species from brown algae padina sp. was 8%. This result is acceptable for sodium alginate water content as set by the Food Chemical Codex that requires less than 15% water content. The measurement of the viscosity obtained is 13.33 cps.Conclusion: These results indicate that the species of brown algae padina sp. has the potential to be one of the basic materials of dental impression material.
Analysis of genotoxic and cytotoxic effects of oral mucosa in smokers and non-smokers after exposed to digital intraoral radiography Dwi P. Wulansari; Aryadi Arsyad; Irene E. Rieuwpassa; Nurlindah Hamrun; Rafikah Hasyim
Journal of Dentomaxillofacial Science Vol. 4 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.046 KB) | DOI: 10.15562/jdmfs.v4i3.961

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Objectives : To analyze genotoxic and sitotoxic indicators of buccal epithelial cells by measuring the number of cells contain micronucleus, pycnosis, karyorrhexis, karyolysis and to determine the change in oxidative stress of  oral mucosa cells using salivary MDA levels between smokers and nonsmokers before and after exposure to intraoral radiographs during endodontic treatment.Material and Methods : This research was an analytic observation research with cross-sectional design. The sample was divided into smokers (n = 5) and non-smokers group (n = 5). The buccal epithelial cells was taken with cytobrush and unstimulated saliva in each group were taken by the draining method shortly before intraoral radiography, 10±2 days after first  day exposure, 10±2 days after second day exposure. The cells were stained using Papanicolau (PAP) kit and observed by pathologist. Genotoxic and cytotoxic indicator measured by counted the number of cells contain mironucleus, pyknosis, karyorrhexis and karyolysis under light microscope with 400X magnification according to the Tolbert criteria in 1000 cells. While oxidative stress of cell measured by salivary MDA with Thiobarbitoric Acid (TBA) assay.Result : The number of micronucleus, pyknosis, karyorrhexis, karyolysis in buccal epithelial cells and salivary MDA levels in smokers was higher than non-smokers (p<0,05). There were no significant differences in genotoxic and cytotoxic indicators and salivary MDA levels before and after the last exposure in smokers and non-smokers (p>0,05).Conclusion : The results of this study indicate that the use of intraoral radiographs is within safe limits despite repeated exposure after several days.
Constructing halitosis sensor for early detection in periodontal diseases Nurlindah Hamrun; Filzah Azalia; Nurul Auliya; Muhammad Riswan
Journal of Dentomaxillofacial Science Vol. 5 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v5i2.1080

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Objective: The purpose of this research is to create a halitosis sensor device that can detect periodontal disease through bad breath.Material and Methods:The method used is MQ 136 gas sensor which possesses high sensitivity to H2S gas and can monitor organic vapor including sulfur well.Results: The result of the resistance value obtained in the sensor is changed to the concentration value of the substance and displayed in the LCD. When the power button is switched on then the power supply from the battery is flowing in the Arduino and LCD. When the “result” button is pressed it will appear the desired result on the LCD in the form of H2S element concentration and also predicted the status of periodontal disease suffered by the patient.Conclusion:This halitosis sensor can detect early periodontal disease experienced by a person so that patients with a suspected periodontal disease can be treated as soon as possible.