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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Matematika & Sains Jurnal SOLMA Pharmaceutical Sciences and Research (PSR)
Lusi Putri Dwita
universitas Muhammadiyah Prof. DR HAMKA (UHAMKA)
Mathematics Medicine & Pharmacology Other

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Penanganan Rehidrasi Setelah Olahraga dengan Air Kelapa (Cocos nucifera L.), Air Kelapa ditambah Gula Putih, Minuman Suplemen, dan Air Putih Samsul Bahri; Joseph Iskendiarso Sigit; Tommy Apriantono; Rini Syafriani; Lusi Putri Dwita; Yoza H. Octaviar
Jurnal Matematika & Sains Vol 17, No 1 (2012)
Publisher : Institut Teknologi Bandung

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Abstract

Telah diteliti pengaruh rehidrasi menggunakan air kelapa dan air kelapa ditambah gula putih, dibandingkan terhadap minuman suplemen yang telah beredar di pasaran. Penelitian ini dilakukan dengan metode double blind cross over design  sebanyak empat kali penelitian dengan masa washout selama satu minggu. Pertama dilakukan pengkondisian status hidrasi, kemudian atlet diminta berlari pada 75% VO2maks selama 1 jam sehingga mengalami dehidrasi. Penggantian cairan tubuh dilakukan setelah berlari yaitu pada periode rehidrasi dengan volume minuman uji yang setara dengan 120% cairan yang hilang selama berolah raga. Rehidrasi menggunakan air kelapa dan air kelapa ditambah gula putih mengembalikan berat badan tubuh dan hematokrit kembali ke normal (mencapai tahap euhidrasi), dengan indeks rehidrasi lebih baik dari pada air biasa (kontrol), yaitu 2,09±0,32, 2,40±0,45,  2,14±0,38 dan 3,02±0,52 berturut-turut  untuk air kelapa, air kelapa ditambah gula putih, minuman suplemen “X”, dan kontrol. Selain itu air kelapa menginduksi produksi urin lebih sedikit dibandingkan air kelapa ditambah gula putih dan minuman suplemen “X”, namun air kelapa ditambah gula putih lebih baik dalam mempertahankan kadar glukosa darah atlet selama periode rehidrasi. Kata kunci: Indeks rehidrasi, Dehidrasi, Air kelapa, Air kelapa ditambah gula putih, Glukosa darah.   Treatment for Rehidration After Exercise with Coconut Water (Cocos nucifera L.), White Sugar Enrichted Coconut Water, Suplement Beverage and Water Abstract The influences of coconut water and white sugar enriched coconut water compared to commercial supplement beverage to heal dehydration, have been investigated. Method used in this assesment was double blind cross over design in four times experiment  and one week washout period. After conditioning athletes’ hydration, athletes ran at 75% VO2max  for one hour until reached dehydration state. Then body fluid loss recovered during rehydration period equal to 120% fluid lost during exercise. Rehydration used coconut water recovered athletes’ condition back to normal through body weight and hematocrit recovery, with rehydration index better than control, which were 2,09±0,32, 2,40±0,45,  2,14±0,38 and 3,02±0,52 respectively for coconut water, enriched coconut water, “X” supplement beverage and plain water (control). Coconut water induced urine production less than sugar enriched coconut water and “X” supplement beverage, but enriched coconut water was better in maintaining athletes blood sugar levels during the rehydration period. Keywords: Rehydration index, Dehydration, Coconut water, White sugar enriched coconut water, Blood glucose.
Penerapan Pola Konsumsi Makanan dan Aktivitas Fisik untuk Mencegah Penyakit Tidak Menular Dwita, Lusi Putri; Maifitrianti, Maifitrianti
Jurnal SOLMA Vol 7 No 2 (2018)
Publisher : Uhamka Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29405/solma.v7i2.1048

Abstract

Pengabdian ini merupakan pendekatan non-farmakologi untuk penanganan dan pencegahan penyakit tidak menular. Mitra yang terdiri dari ibu-ibu Aisyiah pengurus cabang Duren Sawit 1 berserta guru-guru TK Aisyiah 71 termasuk dalam kelompok umur 40-70 tahun. Hasil pemeriksaan awal menunjukkan hasil 100% peserta pengabdian memiliki peresentase lemak diatas nilai normal. Hasil perhitungan body mass index (BMI) menunjukkan 75% peserta dengan BMI melebihi nilai normal. Selain itu, dilakukan juga periksaan tekanan darah, dimana 58% perserta memiliki tekanan darah diatas 120/70 mmHg. Data-data tersebut menunjukkan ibu-ibu Aisyiah memiliki resiko tinggi terkena penyakit tidak menular dan membutuhkan penangan untuk pencegahan hal tesebut. Meskipun sebagian peserta telah mengkonsumsi obat-obatan, namun tetap dibutuhkan penanganan dari segi non farmakologi untuk mendukung keberhasilan pengobatan.  Hasil diskusi dengan peserta pengabdian menunjukkan masalah kesehatan terkait dengan ketidak seimbangan konsumsi makanan. Hasil pengabdian menunjukkan peningkatan pemahaman ibu-ibu Aisyiah dan guru TK Aisyiah terkait pola gizi yang baik, meskipun hasil pengukuran parameter BMI, %tase lemak dan tekanan darah sebulan setelah pemberian materi gizi seimbang dari narasumber menunjukkan perubahan yang belum signifikan. Hal ini menunjukkan bahwa pengabdian ini perlu dilanjutkan ketahap pelatihan untuk dapat memotivasi lebih lanjut perubahan gaya hidup yang lebih sehat.
Neuropharmacological Activity of Nut Grass (Cyperus Rotundus L.) Rhizome Fraction Dwita, Lusi Putri; Dewanti, Ema; Ladeska, Vera; Sediarso, Sediarso; Muntashir, Adnan; Safni, Ulfa; Sari, Rahma Wulan
Pharmaciana Vol 8, No 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.145 KB) | DOI: 10.12928/pharmaciana.v8i2.8938

Abstract

Research in the area of herbal neuropharmacological effects has increased markedly over the past decades. This research was aimed to further investigate neuropharmacological properties of Cyperus rotundus rhizomes fraction by measuring hypnotic-siccative and anticonvulsant activities. The exploratory behavior test was performed using Hole Board method while motor coordination was assessed using Rotarod Test. The result showed that the 70% ethanol fraction of Cyperus rotundus rhizome in has significant (p <0,05) neuropharmacological activities. All three fractions tested (ethanol, ethyl acetate, and n-hexane), the ethanol fraction showed the best hypnotic-sedative and anticonvulsant activities. Ethanol Cyperus rotundus rhizome fraction could decrease the duration of HLE equal to sodium valproate and potentiated the phenobarbital-induced sleep by decreasing the onset and prolonging the duration of sleep. The highest dose of 70% ethanol fraction of Cyperus rotundus rhizome (356.7 mg/kg) showed the best anxiolytic activity comparable to diazepam (p> 0.05). In conclusion, Teki ladang (Cyperus rotundus) rhizome appeared as potent neuropharmacological drug candidate with abilities comparable to synthetics drugs. 
Pembuatan Sirup Jahe Merah dan Pemafaatannya dalam Kesehatan Dwita, Lusi Putri; Maifitrianti, Maifitrianti; Viviandhari, Daniek
Jurnal SOLMA Vol 8 No 1 (2019): Jurnal SOLMA
Publisher : Uhamka Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.831 KB) | DOI: 10.29405/solma.v8i1.3080

Abstract

Pengurus Pembinaan Kesejahteraan Keluarga (PKK) of Pondok Bambu, East Jakarta, was attended by members ranging in age from 30 to 70 years. There had been training on ginger planting by other parties in Pondok Bambu's RPTRA, but there was no follow-up to this activity so that the ginger plants were not well maintained. These PKK members are used to using traditional ginger medicines to maintain health, but the processing is only limited to hereditary knowledge. As educators and practitioners in the pharmaceutical field, we feel that we have an obligation to provide additional knowledge related to the proper way of treating and utilizing ginger for health. This community service activity aimed to increase the knowledge of PKK members about ginger, improve skills in processing ginger into syrup products in the hope of improving the health as well as using this knowledge to run a business in order to increase the economy of the residents. This activity was held at RPTRA Pondok Bambu Berseri using interactive and demonstration methods. The evaluation results showed an increase in knowledge of PKK members of processing ginger syrup and got the benefits of ginger for the health.
Pembuatan Sirup Jahe Merah dan Pemafaatannya dalam Kesehatan Lusi Putri Dwita; Maifitrianti Maifitrianti; Daniek Viviandhari
Jurnal SOLMA Vol. 8 No. 1 (2019)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.831 KB) | DOI: 10.29405/solma.v8i1.3080

Abstract

Pengurus Pembinaan Kesejahteraan Keluarga (PKK) Pondok Bambu, Jakarta timur,memiliki anggota dengan rentang usia berkisar 30 hingga 70 tahun. Beberapa waktu yang lalu pernah diadakan pelatihan penanaman jahe oleh pihak lain di lingkungan RPTRA Pondok Bambu, namun tidak ada tindak lanjut dari kegiatan tersebut, sehingga tanaman jahe tidak terawat dengan baik. Anggota PKK ini sudah terbiasa memanfaatkan obat tradisional jahe untuk menjaga kesehatan, namun pengolahannya baru sebatas pengetahuan secara turun-temurun. Sebagai pendidik dan praktisi di bidang farmasi, maka kami merasa memiliki kewajiban untuk memberikan tambahan ilmu pengetahuan terkait cara pengolahan dan pemanfaatan jahe untuk kesehatan secara benar. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan anggota PKK tentang jahe, meningkatkan keterampilan dalam mengolah jahe menjadi produk sirup dengan harapan dapat meningkatkan kesehatan serta dapat memanfaatkan pengetahuan tersebut untuk menjalankan usaha pembuatan sirup agar dapat meningkat perekonomian warga. Kegiatan ini dilaksanan di RPTRA Pondok Bambu Berseri. Pada kegiatan ini digunakan metode penyuluhan interaktif dan demonstrasi. Hasil evaluasi dari kegitan menunjukkan peningkatan pengetahuan ibu-ibu PKK ini terkat cara pengolahan sirup jahe dan secara langsung merasakan manfaat jahe.
Efek Xilooligosakarida (XOS) dalam Mencegah Diabetes Mellitus Tipe 2 Dwita, Lusi Putri; Rahmi, Hanifah
Pharmaceutical Sciences and Research
Publisher : UI Scholars Hub

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Abstract

Type 2 diabetes mellitus (T2DM) is one of the leading causes of death in Indonesia. Early intervention is very important to delay the development of this disease. This study aimed to determine the effect of XOS (Xylo-oligosaccharide) as prebiotic in preventing insulin resistance. The rats were divided into 5 groups: XOS 2 gr/kg, XOS 1 gr/kg, XOS 0.5 gr/kg, diabetic control, and non-diabetic control. Animals were given the test substances and standard feed for 2 weeks then induced with STZ (streptozotocin) except for non-diabetic control. On the 19th day, the data was collected. The results showed that XOS 2 gr/kg BW could prevent blood sugar elevation which is 57.84% lower than diabetic control and show a comparable cholesterol level to normal control. It can be concluded that administration of XOS showed a significant effect in preventing T2DM.
Pengaruh Variasi Konsentrasi Hidroxy Propyl Methyl Cellulose (HPMC) terhadap Stabilitas Fisik Gel Ekstrak Tembakau (Nicotiana tabaccum L.) dan Aktivitasnya terhadap Streptococcus mutans Yati, Kori; Jufri, Mahdi; Gozan, Misri; Mardiastuti, Mardiastuti; Dwita, Lusi Putri
Pharmaceutical Sciences and Research
Publisher : UI Scholars Hub

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Abstract

Tobacco extract had been proven to have antimicrobial activity against Streptococcus mutans. To maximize the use of tobacco extract on topical use as an antibacterial, it could be formulated into a pharmaceutical preparation. This study aimed to formulate tobacco extract in gel preparation by using Hidroxy Propyl Methyl Cellulose (HPMC) as a gelling agent and to test its activity on S. mutans. The tobacco extract gel was prepared in 3 formulas with variations of HPMC concentration of 1.5% (F1), 2% (F2) and 2.5% (F3). The research began with tobacco extraction, then continued with characteristics evaluation. The extract was formulated in gel form and evaluated for 12 weeks of physical stability. Antibacterial activity was tested using the diffusion method. The evaluation results of tobacco extract gel showed that all formulas were stable during 12 weeks storage. Antimicrobial activity against S.mutans showed inhibitory diameter of F1, F2 and F3, were 9,07 mm, 19,53 mm, and 11,57 mm respectively. The test was continued by determining the relative potential of F2 compared to erythromycin. The test results showed 1.2 x 10-2 relative potential compare to erythromycin. Based on the results of this study, it can be concluded that HPMC concentration difference did not give significant difference to the physical stability of tobacco gel, with the best antibacterial activity on S. mutans obtained from F2.
Co-Authors Daniek Viviandhari Ema Dewanti HANIFAH RAHMI Joseph Iskendiarso Sigit Kori Yati, Kori Ladeska, Vera Mahdi Jufri Maifitrianti Maifitrianti Maifitrianti Maifitrianti, Maifitrianti Mardiastuti Mardiastuti Misri Gozan Muntashir, Adnan Rini Syafriani Safni, Ulfa Samsul Bahri Sari, Rahma Wulan Sediarso Sediarso, Sediarso Tommy Apriantono Viviandhari, Daniek Yoza H. Octaviar