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Hypoglycemic effect of banana peel extract (Musa Paradisiaca Var Kepok) in New Zealand White Diabetes Hyperlipidemia Samiasih, Amin; Subagio, Hertanto Wahyu; Dharmana, Edi; Susanto, Hardono
Health Notions Vol 2 No 11 (2018): November 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Introduction: banana peels just end up in the trash to date. It needs to be thought of waste processing into a more useful product for health. This study aims to determine the effect of peel extract (Musa Paradisiaca var. kapok) toward the blood sugar level of New Zealand White (NZW) rabbits which have diabetes hyperlipidemia. Method: 27 male New Zealand White rabbit, age 4 months, average weight 1.5-2 kg. The raw materials of the ethanol extract were Musa Paradisiaca Var Kepok peels that were obtained from Traditional Market, Demak, Central Java Indonesia. Type of experimental laboratory research was conducted with a randomized control design pre-posttest design. The 104-day study was conducted at LPPT unit 4 UGM that has been standardized internationally. Results: The test results of repeated ANOVA on the blood sugar group 1 (O1) shows that at least 2 measurement times that had significantly different mean values with p-value= 0.003 <0.05. The result of the Friedman test on the blood sugar level for group 2 (O2) showed that at least 2 measurement times having mean value was significantly different with p-value= 0.001 <0.05. The group 3 (O3) indicated that at least 2 measurement times had significantly different value mean with p-value= 0.045 <0.05. There are the differences on blood sugar levels in each group and at each measurement time. Administration of ethanol extract of musa paradisiaca var kepok peels in the group (O1) with dose 200mg / kg bb and dose of 400mg / kg bb in group 2 (O2) have the same effect of hypoglycemia. Conclusion: an ethanol extract of musa paradisiaca var kepok peels have a hypoglycemia effect on New Zealand White rabbit with Diabetic Hyperlipidemia.

Hypoglycemic Effect of Banana Peel Extract (Musa Paradisiaca Var Kepok) in New Zealand White Rabbits with Diabetes Hyperlipidemia Amin Samiasih; Hertanto S. W.; Edi Dharmana; Hardono Susanto
Health Notions Vol 2, No 11 (2018): November
Publisher : Humanistic Network for Science and Technology (HNST)

Introduction: banana peels just end up in the trash to date. It needs to be thought of waste processing into a more useful product for health. This study aims to determine the effect of peel extract Musa Paradisiaca var. kepok(MPvK) toward the blood sugar level of New Zealand White (NZW) rabbits which have diabetes hyperlipidemia. Method: 27 male New Zealand White rabbit, age 4 months, average weight 1.5-2 kg. The 104-day study was conducted at LPPT unit 4 UGM that has been standardized internationally. Results: The test results of repeated ANOVA on the blood sugar group 1 (O1) shows that at least 2 measurement times that had significantly different mean values with p-value= 0.003

HUBUNGAN OBESITAS DENGAN RANGE OF MOTION SENDI PANGGUL DAN FLEKSI LUMBAL PADA DEWASA MUDA Anita Sari Budi Rahardjo; Tri Indah Winarni; Hardono Susanto
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Latar belakang : Obesitas masih menjadi permasalahan kesehatan masyarakat yang mendunia yang dapat menjadi faktor risiko beberapa penyakit termasuk gangguan mobilitas. Obesitas diketahui sebagai faktor yang dapat mempengaruhi besarnya gerakan sendi. Namun, belum ada penelitian mengenai obesitas pada dewasa muda dengan range of motion (ROM) sendi panggul dan fleksi lumbal.Tujuan : Mengetahui hubungan obesitas dengan ROM sendi panggul dan fleksi lumbal pada dewasa muda dan mengetahui perbedaan ROM sendi panggul dan fleksi lumbal pada obesitas kelompok laki-laki dan perempuan.Metode : Penelitian dilakukan pada April-Mei 2016 dengan rancangan penelitian adalah cross-sectional. Subjek penelitian terdiri dari 37 laki-laki dan 23 perempuan usia 18-22 tahun dengan BMI ≥ 25 kg/m2. Data antropometri dan ROM sendi didapatkan dengan mengukur subjek secara langsung. ROM diukur menggunakan goniometer.Hasil : Didapatkan hasil korelasi negatif yang signifikan antara BMI dan fleksi panggul, adduksi panggul dan fleksi lumbal, serta korelasi positif yang signifikan BMI dengan endorotasi panggul. Hasil uji beda ROM laki-laki dan perempuan menunjukkan adanya perbedaan yang signifikan ROM adduksi, endorotasi, dan eksorotasi panggul (p = 0.004, p = 0.000, dan p = 0.000).Kesimpulan : Obesitas dapat menurunkan ROM fleksi panggul, adduksi panggul, dan fleksi lumbal, serta terdapat peningkatan ROM endorotasi panggul. Ada perbedaan yang signifikan pada ROM adduksi, endorotasi, dan eksorotasi panggul dengan rerata ROM yang lebih besar pada kelompok laki-laki dibanding perempuan.

COMPARISON OF DURATION PLAYING DEFENSE OF THE ANCIENTS-2 VIDEO GAME WITH REACTION TIME Yosua Arif Hadi; Yuswo Supatmo; Novi Kusumaningrum; Hardono Susanto
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 6 (2020): DIPONEGORO MEDICAL JOURNAL (Jurnal Kedokteran Diponegoro)
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v9i6.29332

Background: DotA-2 is the most popular MOBA video game, which ranks the second most sold on the steam platform. Reaction time as a physiological parameter to find out how quickly to respond to a stimulus. Some research states that video games can increase reaction time. Objective: To know the correlation of playing video game Defense of the Ancients-2 with the duration of reaction time. Method: The study used cross-sectional design. This study was conducted in the area of the Faculty of Medicine, Diponegoro University. In this study found 42 respondents participated. Score of reaction time is measured using a ruler dropped from the respondent's fingertips. Analysis using Shapiro-Wilk test and Pearson test. Results: There is significant relationship between playing a DotA-2 status and reaction time. The duration of playing DotA-2 video games to the reaction time there were significant differences between the 3 groups. Conclusion: There is a significant relationship between the status of playing video game DotA-2 with reaction time.

Protein Content Test of Tilapia Fish Extract (Oreochromis Mossambicus) before and after Freeze Dry Using Biuret Method Walin; Hardono Susanto; Bagoes Widjanarko; Nurjazuli Nurjazuli
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 3 (2022): Indian Journal of Forensic Medicine and Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i3.18312

Objective: To determine the difference in protein content of tilapia extract before and after drying process.Materials and Methods: This study was designed with a true experimental design. The research sample wastilapia fish extract with 3 replications in each sample. The measurement of protein content was carried out onsamples before and after drying. The drying process of tilapia extract was carried out for 48 hours using a freezedryer. Furthermore, the dried samples were tested for protein content using the biuret method supported by theUV-Vis Spectrophotometer instrument. The testing stages include making the standard solution, determining themaximum wavelength, determining the operating time, and making a standard curve.Results: Showed that the protein content of tilapia extract before and after drying was 2.23% and 27.4%,respectively. The results of statistical analysis showed that there was a significant difference between the proteincontent of tilapia fish before and after drying.Conclusion: There was an increase in protein content of tilapia fish extract after drying by 25.17%.

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