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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Bali Dermatology Venereology and Aesthetic Journal

Yuri Widia, Yuri

Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital Surabaya

Author-ID : 3287774

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Articles

Retrospective Study: Oral Medications for Atopic Dermatitis Widia, Yuri; Hutomo, Marsoedi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease, characterized by recurrent itch. The prevalence of AD in children is 10-20%, while in adults is as many as 1-3%. Several factors are proposed to play role in the pathogenesis of AD as well as genetics, immunological, and environmental factors. There are recent advances in the management of the AD but still not fully satisfactory. Purpose: To evaluate oral medications for AD to improve patients care in the future. Methods: Retrospective study performed in Allergy Immunology Division of Dermatology and Venereology Outpatient Clinic Dr. Soetomo th stGeneral Hospital within January 1 2009 until December 31 2011. Data was collected from medical records. Results: There were 11.7% AD patients who received oral treatment. The most antihistamine given was mebhydrolin napadisilat in 51.5% of patients. The most corticosteroids given was dexamethasone in 33.6% patients. Dexamethasone was given in tapering off in 7.9% patients. The most oral antibiotics given was erythromycin in 4.8% patients and cloxacillin in 0.3% patients. Conclusions: Oral medications mostly used in AD was antihistamine. Some patients were also given corticosteroids. Antibiotics were used if secondary bacterial infection was assessed.Key words: atopic dermatitis, retrospective study, oral medications.

Condylomata Acuminata in Children: Report of Two Rare Cases Yuri Widia; Shinta Dewi Rahmadhani; Sawitri Sawitri; Afif Nurul Hidayati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 2 (2017): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Condylomata acuminata are mostly found in adult patients through sexual contact. Non-sexual transmission should be considered in children with condylomata acuminata. There are no Food Drug Administration (FDA) guidelines approved for condyloma acuminata in children less than 12 years old. Purpose: To report two rare cases of condylomata acuminata in children. Cases: Two girls, aged 1 and 2 years old came at different times to Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Hospital with perianal tumors. Both were born by vaginal delivery. There was no history of the same disease on the genital or the skin of both parents. Physical examinations on the perianal area were multiple flesh-colored papules with ‘cauliflower’ appearance. There was no sign or symptom of sexual abuse. Histopathological examinations in both patient show epidermis with hyperkeratosis, acanthosis, papilomatosis, some epithelial cell show koilocytosis. On the dermis layer there were proliferation from capillary blood vessel, infiltration mononuclear, intact membrane basale and no sign of malignancy. Human papillomavirus (HPV) subtypes examination results were type 11. Discussion: Trichloroacetic acid (TCA) was giving different results on both cases. The patient who did not show improvement with TCA was consulted to pediatric surgery to get electrodessication therapy by hefrycauter. Conclusion: Accurate history and physical examination isneeded to determine the mode transmissions of condylomata acuminata in children. Human papillomavirus (HPV) subtypes examination is not routinely performed and has limitation to determine the mode of transmission, especially in children. Perinatal transmission should be considered in children up to 2 years old. Multiple modalities are available for the treatment of warts in children.

Metal Patch Testing with Nickel, Chromium, and Cobalt in Atopic Dermatitis Patients Yuri Widia; Evy Ervianti; Marsudi Hutomo
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 3 (2017): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Atopic dermatitis (AD) is a cutaneous inflammation characterized by skin hyperreactivity due to complex interplay between genetic susceptibility and environmental allergens. In AD, recurrences are frequent and cause problems. Although elevation of total immunoglobulin E (IgE) level; and positive specific IgE to environmental allergens and food are found in most cases, some AD patients with normal IgE level still recurred and raised the possibility of other factors as a trigger. Datas from some studies showed high frequency of positive results in metal patch testing and improvement in AD after allergen elimination and low metals diet. Based on these studies, metal is considered as a trigger of reccurrences in AD. Nickel, chromium and cobalt are the primary metals that gives high frequency of positive patch test results in patients with intrinsic AD. Purpose: To evaluate metal patch testing results with nickel, chromium and cobalt in atopic dermatitis patients at Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya. Methods: This study was observational cross-sectional descriptive study of patch testing to nickel, chromium, and cobalt at 23 AD patients who met the inclusion and exclusion criteria. Results: Patch testing to nickel sulphate metal gave positive result in 17.39% patients, potassium dichromate 8.7%, and cobalt chloride 4.35%. Four people (17.39%) showed positive patch test results; 3 people (13.04%) showed the value of the normal serum total IgE and 1 (4.35%) showed an increasing total serum IgE level. Conclusions: Metal patch testing against AD can be considered in AD patients with normal IgE values.

Management of Eumycetoma Tjokorde Istri Nyndia Vaniari; Sunarso Suyoso; Linda Astari; Yuri Widia; Sylvia Anggraeni; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 3 (2020): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.3.2020.232-238

Background: Mycetoma is a chronic inflammatory disease of the skin that can extend to the fascia, tendons, muscles, and bones. Caused by a bacterium called actinomycetoma and a fungus called eumycetoma are responsible for mycetoma, both of which must be distinguished because they require different medical therapy. Eumycetoma is a localized disease, chronic, and growing slowly. Most of eumycetoma patients had delays in seeking medical care. Purpose: To provide an overview and discuss various aspects of eumycetoma, including its epidemiology, etiology, pathogenesis, classification, clinical picture, diagnosis, differential diagnosis, and therapy. Review: Eumycetoma infection begins as infectious agents enter through the skin with a minor trauma caused by objects contaminated with fungi, forming granular or granulomatous lesions with tract and sinus in there. The infection can spread from the site of inoculation into the muscles and bones. The diagnosis is based on anamnesis (chronic and painless), the triad of tumefaction, draining sinuses and grains, and laboratory investigation. It’s a difficult case, often recur and difficult to be surgical excisison, so that the best first option therapy is the combination of itraconazole and terbinafine itself as an alternative to surgical therapy at least 6 months. Conclusion: Eumycetoma is an infection caused by a fungus with granulomatous lesions with sinus formation and grains in it. The best first option therapy is the combination of itraconazole and terbinafine although it’s still an early case.

Cat Contact as A Risk Factor for Tinea Capitis Infection Evy Ervianti; Addia Salsabila; Yuri Widia; Arthur Pohan Kawilarang
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.1-4

Background: Tinea capitis (TC) is common infection caused by dermatophytes on the scalp. Cat contact is one of the TC risk factors. Microsporum canis is the most abundant fungi in cats and humans as a zoophilic infection. Cats and carrier cats can infect humans, mostly children. Purpose: To evaluate cat contact as a risk factor for TC patients at the Dermatology and Venereology Outpatients Unit of Dr. Soetomo General Academic Hospital Surabaya in January 2017 - December 2018. Methods: A retrospective study by observation and recording data. The results obtained as a result of the data recap were then processed using tabulation to obtain conclusions. Result: The results obtained from TC cases in 2017 and 2018 are 20 patients. The results were cat contact in 9 patients (45%), aged > 5 years (55,6%), male (55,6%), and lived in Surabaya (88,9%), hair loss (88,9%), crust (100%), M. canis in culture (55,6%), Grey patch type (55,6%), combination of oral Griseofulvin and Ketoconazole 2% scalp solution (88,9%), and patients’ follow up (44,4%). Discussion: More people keeping cats will increase the risk of being infected with feline dermatophytosis. Combination therapy is the best treatment for M. canis. It is important to educate parents to be careful with pet cats that can become carriers. Conclusion: Cat contact was positive in almost half patients, mostly in a male and > 5 years old. The most common signs and symptoms were crust and hair loss, and grey patch.

Epidermolysis bullosa in a twins infant: a rare case Dhea Medisika Hertanti; Ditya Indrawati; Iskandar Zulkarnain; Sawitri; Irmadita Citrashanty; Yuri Widia; Rahmadewi
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 6, Issue 1 (June 2023)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/yxcw3527

Background: Epidermolysis bullosa (EB) is a rare hereditary genodermatosis characterized by blisters due to trauma and temperature. Cases of EB in twin infants are rare. This report will discuss EB in twin infants to improve our knowledge about this genodermatosis. Case: A baby boy with a twins history aged 4 months was consulted by the Pediatric Department with complaints of fluid-filled blisters that have been present since birth. During examination, bullae appeared on the upper and lower extremities. The gram examination and culture results showed Staphylococcus aureus infection and gentamicin sensitivity. The histopathology results showed a subepidermal blister with the dermis layer showed lymphocytic infiltration, which was in accordance with EB. The baby was hospitalized for 5 days and then came back to the outpatient unit with his twin, who had the same complaint. Examination of the second infant revealed multiple erosions and hypopigmented macules on the superior and inferior extremities. Both babies were born at term, normal, adequate weight, and are the first twins. Direct immunofluorescence did not show immunoglobulin G (IgG) and complement C3 deposits in the basement membrane zone. Both infants received symptomatic therapy. Conclusion: Epidermolysis bullosa is a rare case, especially in twins. Electron microscopy is a gold standard for determining EB type. Symptomatic treatment is the main therapy in this population of EB.

Co-Authors Addia Salsabila Afif Nurul Hidayati Arthur Pohan Kawilarang Dhea Medisika Hertanti Ditya Indrawati Evy Ervianti Irmadita Citrashanty Iskandar Zulkarnain Linda Astari Marsoedi Hutomo, Marsoedi Marsudi Hutomo Rahmadewi Sawitri Sawitri Sawitri Shinta Dewi Rahmadhani Sunarso Suyoso Sylvia Anggraeni Tjokorde Istri Nyndia Vaniari

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