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All Journal Indonesian Journal of Tropical and Infectious Disease Care : Jurnal Ilmiah Ilmu Kesehatan Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology
Muhammad Vitanata Arfijanto
1. Division Of Tropical Infectious Disease, Departemen Ilmu Penyakit Dalam FK - Unair RSUD Dr. Soetomo Surabaya 2. Institute Of Tropical Disease Airlangga University
Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Biomolecular and Health Science Journal

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Association Between Neopterin Levels and Outcome in 30 Day HIV/AIDS Naive Patients Lydia Juanita; Usman Hadi; Vitanata Arfijanto
Biomolecular and Health Science Journal Vol. 2 No. 2 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.175 KB) | DOI: 10.20473/bhsj.v2i2.14965

Abstract

Introduction: HIV/AIDS is still a major problem throughout the world even in Indonesia. Some markers can provide information regarding the description of immune activity in HIV/AIDS. Neopterin produced by macrophages as a catabolic result of Guanosine Triphosphate (GTP) is one of them. Neopterin has been widely studied as a prognostic indicator of the course in HIV/AIDS. Until now there have been no studies examine the association between neopterin levels and outcomes in 30 days of HIV/AIDS patients.Methods: A prospective longitudinal analytic study involved 56 samples of HIV/AIDS naive patients from January to April 2019. Serum neopterin levels were measured by the Enzyme Linked Immunosorbent Assay (ELISA) method. Outcome is a living condition or death within the first 30 days of the patient being treated. Discriminant function analysis was used to determine the association between variable and controlling confounding factors using the "R" program. Outputs of p value was significant if <0.05.Results: The average age of the study subjects was 39.7 ± 11 years old with predominantly male gender (71.4%). The median serum neopterin level of the study subjects was 168.13 nmol/L with the lowest levels of 11.78 nmol/L and the highest level of 196.95 nmol/L. Outcomes were grouped live and died, each group at 50%. There was a significant positive association between serum neopterin levels and outcomes in 30 days (p=0.02)Conclusion: Role of neopterin levels still need to be proven as a prognostic factor by evaluating other factors that influence the outcome of HIV/AIDS patients.
Diagnostic Challenge Of Peritoneal Tuberculosis In Woman With Ascites Nenci Siagian; Muhammad Vitanata Arfijanto
Biomolecular and Health Science Journal Vol. 3 No. 1 (2020): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v3i1.19131

Abstract

Tuberculosis (TB) is a major health global issue including extrapulmonary tuberculosis (EPTB). The one of manifestation of EPTB is peritoneal TB that constitutes 2% from all cases of pulmonary TB around the world. The diagnosis of peritoneal TB is quite challenging because many cases have symptom that similar to other diseases and those often necessary need further specific examinations such as PCR, culture and radiologic examination. We reported a case report of peritoneal tuberculosis in woman with ascites.
Co-Authors Agung Dwi Wahyu Widodo Aryati Aryati Asmarawati, Tri Pudy Bramanton Bramantono - Brian Eka Rachman Dominicus Husada Heri Krisnata Ginting Ilham Munandar Jihan Kalishah Lydia Juanita M Thohirin Ramadhani Maria Lucia Inge Lusida Meiwinda Rizky Nurhidayah Moh. Hamzah Raka Pratama Musofa Rusli Nasronudin Nenci Siagian Prihartini Widiyanti S. Ugroseno Yudho Bintoro Siti Irma Mashitah Siti Nurul Jannah Ulfa Kholili Usman Hadi Usman Hadi