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All Journal journal of internal medicine Indonesian Journal of Tropical and Infectious Disease Biomolecular and Health Science Journal CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology
Bramantono -
1. Division Of Tropical Infectious Disease, Departemen Ilmu Penyakit Dalam FK - Unair RSUD Dr. Soetomo Surabaya 2. Institute Of Tropical Disease Airlangga University
Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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PROFIL PENDERITA SEPSIS AKIBAT BAKTERI PENGHASIL ESBL Irawan, Danny; -, Hamidah; -, Purwati; EA, Triyono; -, Bramantono; V, Arfianto; U, Hadi; -, Nasronudin; -, Suharto; E, Soewandojo
journal of internal medicine Vol. 13, No. 1 Januari 2012
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (74.799 KB)

Abstract

Extended Spectrum !-Lactamases (ESBL) is plasmid enzyme which catalyzing hydrolysis and inactivation !-lactamantibiotic, including third generation of Cephaloporin, penicillin and aztreonam. This enzyme is mutation of !-lactamaseTEM-1, TEM-2, and SHV-1 which commonly found in Enterobacteriaceae and normally have resistance to penisillin andrst generation celaphorin. The incidence of infection cause by ESBL bacterial is increasing worldwide. AntimicrobialResistance in Indonesia: prevalence and prevention (AMRIN study) is showed incidence of infection ESBL bacterial 29%E. coli, and 36% K. pneumonia. This study is descriptive and restrospectively learn about prole of DMK with septicemiapatient caused by ESBL bacterial in Internal Medicine Ward RSUD Dr Soetomo within 1st January 2010 until 30th June2011. Sixty four patient were recruited and 48 patients with ESBL bacterial positive. Mortality rate is 16.7%, severe septiccondition 27.08%, septic shock 14.58%. The result of positive ESBL bacterial was found from urine culture (37.5%).Sensitivity of antibiotics results are meropenem (98.07%), amikacin (88.46%).
Profile of Pneumocystis JiroveciiPneumoia in HIV/AIDS Patients in Dr. Soetomo General Hospital of East Java Province Pius Sebastian Ginting; Bramantono; RestiYudhawati Meliana; Musofa Rusli
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i2.17933

Abstract

Background: Human immunodeficiency virus (HIV)-infected patients if not treated will experienceacquired immunodeficiency syndrome (AIDS). People with AIDS will suffer opportunistic infection.One of the common opportunistic infections is Pneumocystis jirovecii pneumonia (PCP). PCP is aninfection caused by the fungus Pneumocystis jirovecii which infects patient’s lungs. The purpose of thisstudy is to analyze the profile of HIV/AIDS patients with PCP in Dr. Soetomo Hospital.Methods: This is a retrospective descriptive study based on medical records obtained from the inpatientward of Dr. Soetomo General Hospital Surabaya. A total 21 patients enrolled in this study who met theinclusion criteria. The data are retrospectively described by demographic characteristics, CD4 count,clinical symptoms, blood gas, and lungs radiographic features.Conclusion:Major findings of PCP in HIV/AIDS patients was in the group of age 25-49 years (85,7%),male (85,7%), high school graduate (71,4%), employed and unmarried (66,7%). The most commonclinical symptoms were dyspnea (100%), PaO2 ≥70 mmHg (61,97%), CD4 count <50 cells/μL (76,2%)and the most common radiographic features was bilateral interstitial infiltrates (95,2%).
Acquired Immunodeficiency Syndrome Patient with A Dengue Hemorrhagic Fever Co-Infection Dedy Hadi Prawono; Bramantono
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15638

Abstract

Infection of human immunodeficiency virus (HIV) is the most infectious disease in tropic disease infection and co-infection of HIV is very large, one of which is DHF. Research on DENV-HIV is still limited. A patient 29-year-old, referred to Dr. Soetomo Hospital with chief complain nausea from yesterday. Accompanied epigastric pain, stomach feel full and decreased of appetite. Laboratory test finding Hb 18,6 g/dL, leukosit 2910/mm3, trombosit 9000/mm3, HCT 51,5 %, Anti dengue IgG 29,9 and IgM 10,5 on 2nd day admission, Anti dengue IgG 14,3 and IgM 13,1 on two weeks from out of admission. The most common symptom in HIV patients with co-infection DHF is fever and loss of appetite. Patients with DENV-HIV have plasma leakage. Patient with DENV-HIV found an increase in eosinophil and pulse but found a lower increase in serum hematocrit compared with DENV patients, but lower hematocrit levels in this patients can be caused in patients using zidovudine, which is associated with anemia caused by zidovudin side effects.
A Patient with Suspected Diphtheria Muhammad Vitanata Arfijanto; Siti Irma Mashitah; Prihartini Widiyanti; Bramantono Bramantono
Indonesian Journal of Tropical and Infectious Disease Vol. 1 No. 2 (2010)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (718.818 KB) | DOI: 10.20473/ijtid.v1i2.2169

Abstract

It was reported that a mature woman, Mrs. S, 42 years old with several complaints and symptoms such as fever, swallowing painweak body, swollen tonsil with beslag, dirty uvula of mouth cavity and tongue, and bullneck. The final diagnosis indicated that thepatient was suspected diphtheria, candidiasis oris, sepsis, and pneumonia. The sudden death of the patient was probably caused bymyocarditis.
The Bacterial Pneumonia Characteristics based on Climate and Meteorological Parameters in Indonesia, the Tropical Country: A Preliminary Study Bramantono Bramantono; Brian Eka Rachman; Erika Marfiani; Neneng Dewi Kurniati; Muhammad Vitanata Arifijanto; Tuksin Jearanaiwitayakul
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.26926

Abstract

Introduction: As a tropical country, Indonesia has the potential to influence the characteristics of infectious diseases. The purpose of this study was to see how the pattern of pneumonia on various weather components such as rainfall, humidity, and temperature.Methods: This study was carried by retrospective screening in the infectious ward in one of the tertiary referral hospitals.Results: A total of 876 cases of pneumonia from eight treatment rooms were included in the study. The highest pneumonia cases occurred in February with 239 (27.2%) cases followed in April and May with 169 (19.2%) and 159 (18.2%) cases respectively. After microbiological examination, bacterial growth was found in 191 cases. The highest number of bacteria was found in February with 62 (32%), followed by May with 33 (17.2%) and April with 31 (16.2%) samples. Most of the bacterial grown were gram-negative (94.3%), dominated by Klebsiella pneumoniae (35%), followed by Acinetobacter baumanii 17.2%  and Pseudomonas aeruginosa  12%. On the examination of antibiotic sensitivity, it was found that amikacin has a consistently high sensitivity (90%) for pneumonia caused by most bacterial causes (Acinetobacter baumanii, Klebsiella pneumoniae, and Escherichia coli).Conclusion: The study did not show any remarkable bacterial patterns based on weather components such as rainfall, humidity, and temperature during the rainy season. However, increasing the surveillance period will provide a better insight into the bacterial pattern and can compare it in the rainy and dry seasons.
Tuberculous Lymphadenitis coexists with Non-Hodgkin Lymphoma Nenci Siagian; Bramantono Bramantono; Usman Hadi
Current Internal Medicine Research and Practice Surabaya Journal Vol. 1 No. 2 (2020): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE JOURNAL SURABAYA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v1i2.21458

Abstract

Tuberculous Lymphadenitis (TBLN) is most common extrapulmonary tuberculosis. The common symptom of TBLN is cervical lymphadenopathy which is known to mimic numerous pathological conditions like NHL. Coexistency TBLN and lymphoma is  a rare. A woman, 56 years old, had chief complaint of cervical masses since 2 months ago. She had history of weight loss, fever and night sweats but no history of chronic cough. From physical examination and supporting examination, the patient was diagnosed with TBLN coexists with NHL. She got antituberculosis drug (ATD) for 2 weeks before chemotherapy. The patient died of septic shock 9 days later after chemotherapy. From HPE examination, TBLN and NHL may show simillar feature so Zhiel-Neelsen staining and Immunohistochemical are important to confirm each disease. ATD was given to supress the mycobacterium activity before chemotherapy. However the patient had febrile neutropenia after chemotherapy and died of septic shock. Both TBLN and NHL may occur with simillar sign and symptom and HPE. Further examinations have to be done to confirm the diagnosis of both disesases. Although ATD had given to prevent Tb infection progresivity. On 7 days after chemotherapy she had febrile neutropenia and lead to death due to septic shock.
Diagnostic Patterns of Suspected Covid-19 Patients Using Scor Covid-19, PCR Test and Serological Test in Dr. Soetomo Hospital Surabaya, Indonesia Usman Hadi; Bramantono Bramantono; M Vitanata; Musofa Rusli; Brian Eka Rahman; Tripudi Asmarawati; Erika Marfiani; Erwin Astha Triyono
Current Internal Medicine Research and Practice Surabaya Journal Vol. 2 No. 2 (2021): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v2i2.28956

Abstract

Objective: To find out the diagnostic pattern of COVID-19 using RT-PCR or a rapid antibody test in the suspected group of patients.Method: The study was conducted in  Dr. Soetomo General Hospital (referral hospital for covid-19, 1500 beds). The study used data on patients with suspected covid-19 who were hospitalized at the Dr. Soetomo General Hospital in Surabaya.Result: There were 200 suspected COVID-19 patients enrolled in this study, the main complaints of cough, fever, dyspnoea, around 69.5%, 75%, and 76.5%, respectively. Although not a common symptom, it seems that anosmia (14%) is typical for COVID-19. Based on this scoring system, a total of 196 patients had a high risk of being infected with COVID-19, and 125 (64%) of them finally showed a positive PCR test. PCR test mostly positive (62.5%), while serological test (rapid immunoglobulin test) mostly nonreactive, but there were no significant differences between PCR and Serological test (p=0.16 OR: 1.5(0.84-71). Furthermore, if we compare the various existing variables, namely the covid-19 score, immunoglobulin rapid test, and radiological examination, only the radiological examination results can be used as a strong predictor of positive PCR results (p=0.005, OR: 1.68 (0.17-16.43).In this study, we found that abnormal chest radiographs are a good parameter for diagnosing COVID-19, (OR: 2.92; 95% CI, 1.34 -6.34).Conclusion: The initial radiological examination combined with the clinical symptoms of Covid-19 is the most important thing to predict the presence of this disease.
EXPANDED DENGUE SYNDROME Agustinus Vincent; Bramantono -; Usman Hadi; Muhammad Vitanata Arifijanto
Current Internal Medicine Research and Practice Surabaya Journal Vol. 3 No. 1 (2022): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v3i1.32536

Abstract

ABSTRACTDengue viral infection (DVI) is a debilitating arthropod-borne disease that has been rapidly spread in several regions of the world in recent years. The spectrum of disease varies from mild self-limiting illness to dengue fever (DF) to more severe and fulminating forms, i.e., dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS),and expanded dengue syndrome (EDS). The pathogenesis of EDS is not clear amid lack of studies on animal models. In the absence of in vitro experiments, disease spectrum is difficult to be elucidated and mimicked for humans.Recent advances on research on atypical complications of EDS demonstrate the involvement of other major organs such as the kidney, lung, heart, and central nervous system. Histopathological findings demonstrate the presence of hemorrhage, edema, and inflammatory infiltrates in these organs.The spectrum of Dengue viral infection varies from mild self-limiting illness to dengue fever to more severe and fulminating forms, i.e., dengue hemorrhagic fever, dengue shock syndrome, and expanded dengue syndrome.  Apart from the classical presentation, dengue infection can result in a myriad of unusual clinical manifestations, which are grouped under the title expanded dengue syndrome. These findings urge more focused and comprehensive investigations to explore such relationships so that high-risk patients could be identified immediately during their presentation to the hospitals.Keywords: Expanded dengue syndrome, Pathogenesis, Organ-specific manifestation
Co-Authors Agustinus Vincent Arfianto V Brian Eka Rachman Brian Eka Rahman Danny Irawan Dedy Hadi Prawono Erika Marfiani Erwin Astha Triyono Hadi U Hamidah - M Vitanata Muhammad Vitanata Arfijanto Muhammad Vitanata Arifijanto Muhammad Vitanata Arifijanto Musofa Rusli Nasronudin Nasronudin Nenci Siagian Neneng Dewi Kurniati Pius Sebastian Ginting Prihartini Widiyanti Purwati - Resti Yudhawati Siti Irma Mashitah Soewandojo E Suharto - Tripudi Asmarawati Triyono EA Tuksin Jearanaiwitayakul Usman Hadi Usman Hadi Usman Hadi