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Seorang Pria 21 Tahun dengan Urin Berwarna Gelap Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 5 No 1 (2019): Nommensen Journal of Medicine
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.955 KB) | DOI: 10.36655/njm.v5i1.82

Abstract

First published by Strubing in 1882, Paroxysmal Nocturnal Hemoglobinuria (PNH) is a chronic acquired disorder characterized by the occurrence of intravascular hemolysis and hemoglobinuria which commonly occurs when patients sleep at night, caused by cellular abnormalities due to somatic mutations that cause intrinsic damage on the red blood cell membrane, making it more susceptible to complement lysis. The incidence of PNH varies greatly in various populations and is more common in Southeast Asia. In general, the incidence is estimated to be 1 -1.5 cases / million population. This case is more common in young adults, but can also be found in children and parents. In general the clinical picture of PNH includes symptoms of anemia, hemoglobinia, signs of bleeding, and gastrointestinal complaints. Diagnosis can be determined through blood, urine, bone marrow and cytogenetic examination. We reported the case of a 21-year-old man with complaints of pale face, easy fatigue and tea colored urine in the morning. After several laboratory tests and aspiration of the bone marrow, PNH diagnosis is made. Glucocorticoids used as therapy, and patients are discharged with clinical improvement.
Uji Aktivitas Antibakteri Dari Air Perasan Bawang Putih Terhadap Bakteri Salmonella Typhi Olivia Yolanda Pasaribu; Ade Pryta Simaremare; Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.231 KB) | DOI: 10.36655/njm.v6i1.233

Abstract

Background : Garlic is a plant which is used to treat various types of diseases, especially the ones caused by bacterial infection. Allicin in garlic is one of the active compounds which has an antibacterial effect. Some studies found that garlic has an inhibitory effect on Salmonella typhi. Objective : This study aimed to determine the antibacterial effect of garlic juice against Salmonella typhi. Methods : This study was an experimental-laboratory research using disc diffusion method on MHA media. This study used five concentrations, namely 12.5%, 25%, 50%, 75%, and 100%. Amoxicillin and aquadest were used as positive and negative controls. The inhibition zone was determined by observing the clear zone around the disc then the results of the study were compared with positive control with CLSI 2017 guidance table where Salmonella typhi was susceptible when the amoxicillin inhibitory diameter zone was ≥ 17 mm, intermediate was 14-16 mm, and resistant was ≤ 13 mm. Results : The results showed that garlic juice has an antibacterial effect on various consentration. The minimum concentration of garlic juice to inhibit the growth of Salmonella typhi is on 50% with 19.25 mm diameters. Conclusion : There was an antibacterial effect of garlic juice on Salmonella typhi.
Pengaruh Pemberian Alpukat terhadap Kadar Kolesterol LDL Darah pada Mahasiswa/i Obesitas di Fakultas Kedokteran Universitas HKBP Nommensen Medan Komandaniel Simanullang; Joseph Partogi Sibarani
Nommensen Journal of Medicine Vol 6 No 1 (2020): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (287.11 KB) | DOI: 10.36655/njm.v6i1.237

Abstract

Background: Low Density Lipoprotein (LDL) is a lipoprotein that contains more cholesterol. High levels of blood LDL cholesterol are associated with obesity and increased of risk factor of cardiovascular disease. Avocado (Persea americana) is a well known and popular fruit in society. The active ingredient (omega 9-oleic acid) of avocados can be use to decrease LDL cholesterol levels and increase HDL (High Density Lipoprotein) cholesterol levels in blood in order to reduce the risk factor of cardiovascular disease. Objective: This study aims to determine the effect of avocado consumption on blood LDL cholesterol levels in obese students in Medical Faculty of Universitas HKBP Nommensen. Method: This study used a pre-experimental design one group pretest and posttest study. Subjects were 20 obese students of Medical Faculty of Universitas HKBP Nommensen and selected by simple random sampling technique. For the first 14 days, samples are given dietary intervention and the next 14 days given dietary intervention and avocado juice. Measurement of LDL cholesterol levels was done before and after 14 days given avocado juice. Data analysis used paired T test to analyze differences in blood LDL cholesterol levels before and after being given avocado juice. Results: The results are average value of blood LDL cholesterol levels on pretest was 137.1 mg / dL and posttest was 128.25 mg / dL with mean reduction was 8.85 mg / dL. Paired T test analysis shows that the avocados effect to blood LDL cholesterol is significantly influenced with value of p = 0.036 (p <0.05). Conclusion: There is an effect of avocado consumption on blood LDL cholesterol levels.
Pengaruh Pemberian Alpukat Terhadap Kadar Kolesterol Total Darah Pada Mahasiswa/i Obesitas Di Fakultas Kedokteran Universitas HKBP Nommensen Medan Tahun 2019 Syupiarni Putri Waruwu; Joseph Partogi Sibarani; Saharnauli Janna Verawaty Simorangkir
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.113 KB) | DOI: 10.36655/njm.v6i2.240

Abstract

Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.
Manifestasi Penyakit Kulit pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Dr. Pirngadi Medan Dione Larissa Simanjuntak; Kristo Nababan; Joseph Sibarani
Nommensen Journal of Medicine Vol 6 No 2 (2021): Nommensen Journal of Medicine: Edisi Februari
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.571 KB) | DOI: 10.36655/njm.v6i2.242

Abstract

Background: Diabetes mellitus (DM) is a metabolic group with characteristic hyperglycemia that occurs due toabnormal insulin secretion, insulin action, or both. DM is often called the silent killer because the patients knowthey has DM only after the patient experiencing complications and manifestations. It is estimated that 30-70% of DM patients experience skin manifestations during the disease process. The relationship between the appearance of skin manifestations with diabetes mellitus is not yet known, but it is suspected due to chronic hyperglycemia and abnormalities of the immune system.Objective: To determine skin diseases in patients with type 2 diabetes at General Hospital Dr. Pirngadi Medan.Methods: This research was a descriptive study with a cross-sectional study design conducted at Dr. GeneralHospital Pirngadi Medan. Data collection was carried out through 29 medical records of patients with diabetesmellitus from January 2018 to December 2018. Samples were selected by total sampling.Results: From 29 samples studied, there were six types of skin manifestations. The most common skinmanifestations are Diabetic Ulcer (62.07%), followed by Steven Johnson Syndrome and diabetic gangrene, which both are equally 13.80%. The other skin manifestations are herpes zoster, gluteal abscess, and bullous pemphigoid (3.44%).Conclusion: The most common manifestation of the skin in patients with type 2 DM is Diabetic Ulcer.
MENINGKATKAN KEMAMPUAN KETRAMPILAN BERNYANYI GENERASI MUDA DI GEREJA HKBP BERASTAGI KABUPATEN KARO Junita Batubara; Jubilezer Sihite; Ken Steven; Ronald Heriko Saragih; Kamaluddin Galingging; Emmi Simangunsong; Ance J. Panggabean; Joseph Sibarani
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2023): Volume 4 Nomor 1 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i2.12034

Abstract

Huria Kristen Batak Protestan atau yang biasa disebut dengan HKBP, sebagian besar jemaatnya adalah orang Nasrani yang bersuku Batak. Sampai Sekarang gereja HKBP sudah menyebar luas hingga ke luar negeri. Pada Kesempatan ini, Pengabdian Masyarakat dilaksanakan di Gereja HKBP Berastagi, dimana gereja ini berdiri pada tahun 1940, dengan jumlah anggota jemaatnya sekitar 1424 orang (156 KK). Gereja ini melakukan kebaktian ibadah setiap Minggunya sebanyak dua kali yaitu pada pukul 08.00wib dan pukul 10.00wib. Dilihat dari jumlah jemaatnya, lebih banyak orangtua (lansia) sebagai anggota gereja daripada naposobulung atau disebut muda-mudi gereja. Kemampuan bernyanyi muda-mudinya, bisa dikatakan kurang mampu dikarenakan kurangnya pelatihan bernyanyi khususnya nyanyian dari Buku Ende. Dengan adanya fakta tersebut maka dilakukanlah pelatihan bernyanyi untuk menambah ketrampilan muda-mudi gereja sebagao songlieder. Adapun metode yang digunakan adalah dengan melakukan ceramah dan pelatihan langsung terhadap mereka dengan cara pengenalan frasering, artikulasi, vibrasi, dan intonasi. Berdasarkan uraian latar belakang di atas maka pelatih menerapkan bagaimana teknik vokal yang benar dari lagu Buku Ende Nomor 716 “Di Na Mamolus Sandok Ngoluon”di gereja HKBP Berastagi khususnya sebagai seorang song lieder, sehingga mereka mampu menyanyikan lagu tersebut ketika saat ibadah di gereja HKBP Berastagi.