Purwantyastuti Purwantyastuti
Departemen Farmakologi Fakultas Kedokteran UI

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Lipid peroxides level in the Indonesian elderly Purwantyastuti, Purwantyastuti; Kamso, Sudijanto; Suyatna, F. D.
Medical Journal of Indonesia Vol 14, No 2 (2005): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.299 KB) | DOI: 10.13181/mji.v14i2.174

Abstract

A cross-sectional study was done to see the possible association of plasma lipid peroxides in the elderly with age and other factors. Plasma lipid peroxides is a product of free radical reactions which according to the latest theory of aging is the cause of aging process. Lipid peroxides were also found high in coronary heart disease. Four hundred forty relatively healthy elderly, age 55-85 years, were randomly chosen from free living elderly under guidance of health care centers (PUSKESMAS) in Jakarta. Anamnesis and physical examination were done in the morning in the health centers. Blood samples were taken in fasting conditions, plasma lipids and lipid peroxides were measured according to standard methods. There was an age difference of lipid peroxides level in the elderly, which increased with age up to 70 years old. Elderly 70 years old and over had low plasma lipid peroxides. The level was not related to high plasma lipids. Higher level was found when more chronic degenerative diseases were found. (Med J Indones 2005; 14: 71-7)Keywords: lipid peroxides, aging
Nutritional status of hyperlipidemics elderly in Indonesia according to body mass lndex (study in four Indonesian big cities) Kamso, Sudijanto; Purwantyastuti, Purwantyastuti; Rumawas, Yohanna S.P.; Lukito, Widjaja
Medical Journal of Indonesia Vol 14, No 2 (2005): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.283 KB) | DOI: 10.13181/mji.v14i2.184

Abstract

The objective of this study was to assess the nutritional status of hyperlipidemics elderly. A cross sectional study was undertaken in 4 big cities in Indonesia using multistage random sampling. The respondents were 656 hyperlipidemics and non hyperlipidemics elderly who were the subsample of 1261 sample of a larger population study. Data were collected through anthropometric measurements and biochemical blood analysis. To determine the nutritional status by Body Mass Index (BMI) the criteria used for elderly men and women are as follows, underweight BMI ≤ 18.5 kg/m2, normoweight BMI 18.5 - 24.9 kg/m2, overweight BMI 25 - 29.9 kg/m2, and obese BMI ≥ 30 kg/m2. To determine lipid status, the criteria used are as follows, hyperlipidemics elderly, those who had plasma total cholesterol ≥ 240 mg/dl and or triglycerides ≥ 200 mg/dl. Prevalence of hyperlipidemics in elderly women is higher then elderly men, 56.2% vs 47.0%. The BMI of hyperlipidemics is mostly overweight (60.4%) and obese (57.1%) for elderly men; and mostly normoweight (59.1%) and overweight (59.5%) for elderly women. The prevalence of hyperlipidemics among undernourished elderly men and women were also quite high, 38.7% and 31.6% respectively. (Med J Indones 2005; 14: 97-100)Keywords : BMI, hyperlipidemics, elderly
Determinants of systolic blood pressure in Indonesian elderly men: In factor analysis perspective (A study in four Indonesian big cities) Kamso, Sudijanto; Purwantyastuti, Purwantyastuti
Medical Journal of Indonesia Vol 15, No 2 (2006): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (141.753 KB) | DOI: 10.13181/mji.v15i2.224

Abstract

The objective of this study was to assess the determinants of systolic blood pressure in elderly men. A cross sectional study was undertaken in 4 big cities in Indonesia using multistage random sampling. The respondents were 320 elderly men who were the sub-sample of 981 sample of a larger population study. Data were collected through anthropometric measurements, biochemical blood analysis, nutrient intake assessment, activity index and stress score. Two type of statistical analysis techniques were used to determine the determinants of systolic blood pressure in elderly men; multiple regression analysis and factor analysis. This study shows that determinants of systolic blood pressure, analyzed with these two types of analysis, multiple regression and factor analysis, resulting in no contradictory result. Direct multiple regression analysis to all independent variables showed that there was correlation between systolic blood pressure with fat mass, and LDL cholesterol. Multiple regression analysis to components resulting from factor analysis showed that there was positive correlation between systolic blood pressure with fat mass, body mass index (BMI), sum of skin-folds and waist circumference. (Med J Indones 2006; 15:115-20) Keywords: Systolic blood pressure, fat mass, LDL cholesterol, body mass index, sum of skin-folds, waist circumference, elderly men
Socio-Economics of Childhood Pulmonary Tuberculosis with Adult Tuberculosis Household Contacts in Daerah Istimewa Yogyakarta Province Asyary, Al; Junadi, Purnawan; Purwantyastuti, Purwantyastuti; Eryando, Tris
Makara Journal of Health Research Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Since the tuberculosis (TB) disease in children constitutes a global health problem that has long been neglected, this study sought to predict socioeconomic factors as public-health determinants that could protect children who were exposed to TB in their household. Method: A case-control study of 132 children (under 14 years old) who shared their household with adults suffering from pulmonary TB was conducted in the Province of Daerah Istimewa Yogyakarta. This study consisted of an interview and anthropometry measurement for the controls screening test, while the cases were monitored by pediatricians with a scoring system childhood TB diagnosis from the secondary hospital database. A multiple logistic regression was used to analyze the results. Results: A healthy housing condition, predicted by a naturally illuminated luminary bedroom prevented the incidence of the childhood TB disease (p = 0.043) even if exposed to adult TB in their environment (p = 0.775). Conclusions: Healthy housing factors with good sunlight protected children especially at the early stage, when there were active pulmonary TB adult household contacts. Ventilation and morning sunlight facilitated air circulation, vitality and the body’s immune system towards TB protection.