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All Journal MNJ (Malang Neurology Journal) Majalah Kesehatan FKUB Journal of Issues in Midwifery
Indriati Dwi Rahayu
Laboratorium Anatomi Histologi Fakultas Kedokteran Univ.Brawijaya
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Journal of Issues in Midwifery

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Pengaruh Pemberian Air Tape Ketan Putih terhadap Kadar Hemoglobin Tikus Rattus norvegicus Bunting Laili, Sauli Nur; Mayangsari, Elly; Rahayu, Indriati Dwi
Journal of Issues in Midwifery Vol 2, No 2 (2018)
Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.996 KB) | DOI: 10.21776/ub.JOIM.2018.002.02.2

Abstract

Tape merupakan hasil proses fermentasi yang akan menghasilkan alkohol. Pada beberapa daerah, banyak larangan ibu hamil untuk mengkonsumsi tape karena dipercaya dapat menyebabkan keguguran. Keguguran merupakan salah satu dampak dari anemia. Oleh karena itu penelitian ini bertujuan untuk mengetahui pengaruh pemberian air tape ketan putih terhadap kadar hemoglobin pada tikus Rattus novegicus bunting. Penelitian ini menggunakan desain experimental sejati dengan rancangan penelitian Post Test Only Control Group Design. Sampel yang digunakan sebanyak 20 tikus bunting yang dibagi menjadi 4 kelompok; kelompok kontrol (K), kelompok perlakuan dengan 3 dosis air tape ketan putih dengan kadar 2,79% (P1=20 ml/kgBB, P2=30 ml/kgBB, P3=40 ml/kgBB). Air tape ketan putih diberikan hari pertama sampai hari ke-19 kebuntingan. Kemudian pada hari ke-20 tikus dikorbankan dan diambil darahnya dari jantung untuk penghitungan kadar hemoglobin. Hasil pada penelitian ini menunjukkan bahwa kadar hemoglobin setelah perlakuan menunjukkan kecenderungan menurun tetapi tidak berbeda secara signifikan p = 0,1 (p>0,05). Namun berdasarkan hasil uji d-type effect size pada P3 menunjukkan pengaruh yang sangat besar dengan ES = 1.40540541 dalam menurunkan kadar hemoglobin. Hasil uji korelasi pearson p= 0,017 (p<0,05) menunjukkan ada hubungan yang cukup kuat dan berlawanan arah p=– 0,529 (p>0,5). Kadar hemoglobin setelah perlakuan menunjukkan kecenderungan menurun tetapi tidak berbeda secara signifikan. Kata kunci: hamil,air tape ketan putih, kadar hemoglobin
Pengaruh Pemberian Ekstrak Kulit Buah Manggis (Garcinia mangostana L.) Menghambat Flexi Cranial Embrio Ayam Umur 48 Jam Anggraeni, Yessy Mulyanur; Rahardjo, Bambang; Rahayu, Indriati Dwi
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Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.JOIM.2020.004.03.3

Abstract

Embryonic development forms three layers of germinativum that is endoderm, mesoderm and ectoderm. At the beginning of intrauterine fetus exchange of substances through diffusion, but in line with the development of the embryo, nutrition is not obtained through diffusion alone. Endoderm lining mesoderm cells will then be formed angioblasts as an early sign of vascularity. In the development of flexi cranial can be known from the development of the brain and heart which is characterized by bending the head of the embryo and decreased heart from the cranial down. The development of a normal vascular system will have an effect on organogenesis and morphogesis processes. If there are disturbances in the process of growth and development at that stage can cause congenital abnormalities. Xanthones mangosteen peel is rich in benefits, but in research on the effects of xanthones on embryos is still very limited and has not been able to explain their effects on the condition of the fetus. The study was conducted with the aim to determine the effect of mangosteen peel extract inhibiting the flexi cranial of 48 hours chicken embryos using doses of 100 µg/mL, 150 µg/mL and 200 µg/mL. Mangosteen peel extract is injected into chicken eggs less than 7 days after oviposition then incubated for 48 hours. The results showed that mangosteen peel extract inhibited flexi cranial of chicken embryos with Chi-Square test results (p = 0.002). The conclusion of the study was that exposure to mangosteen peel extract inhibited flexi cranial and gave significant results.
Co-Authors Agnestia Naning Lovita, Agnestia Naning Agustina Tri Endharti Anggraeni, Yessy Mulyanur Anik Puryatni Bambang Prijadi Bambang Rahardjo Elly Mayangsari Ernst Randy Nuralim, Ernst Randy Estiani Kusumaningrum, Estiani Laili, Sauli Nur Paundralingga, Obed Trinurcahyo Kinantyo Rachmad Sarwo Bekti, Rachmad Sarwo Sari, Vidia Purnama Vanji Budi Himawan, Vanji Budi