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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Penelitian Kesehatan Media Ilmu Kesehatan JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Farmasi Indonesia JFIOnline Abdimas Altruis: Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Kunir: Jurnal Farmasi Indonesia (KJFI)
Wiwin Herdwiani
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Media Ilmu Kesehatan

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Efektivitas rimpang kunyit hitam (curcuma caesia roxb.) terhadap penurunan glukosa darah dan perbaikan ginjal tikus diabetes nefropati Zakiyyah Qurrotul Aini; Wiwin Herdwiani; Tri Wijayanti
MEDIA ILMU KESEHATAN Vol 12 No 2 (2023): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v12i2.874

Abstract

Background: Diabetes Mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Diabetic nephropathy is a degenerative kidney vascular disorder that has a relationship with impaired carbohydrate metabolism or sugar intolerance (Diabetes Mellitus). Black turmeric (Curcuma Caesia Roxb.) is widely used by the community as a traditional medicine and has potential as an antidiabetic.Objective: This study aims to determine the effect of black turmeric extract on decreasing blood glucose levels and its effect on improving kidney histopathology in diabetic nephropathy rats.Method: This research was conducted at the Laboratory of the Center for Food and Nutrition Studies, University of Gajah Mada for the period October-November 2022 consisting of 6 groups. STZ-Na induced rats to obtain a state of hyperglycemia. Examination of blood glucose levels using the GOD-PAP method (enzymatic photometric test).Results: The percentage of blood glucose is decreased levels was 16.75% and repaired kidney histopathology was 6.67% as a score mild damage category (1).Conclusion: Black turmeric rhizome extract (Curcuma Caesia Roxb.) can reduce blood glucose levels and improve kidney function at a dose of 400 mg/kg BW.
Co-Authors - SUHARTINAH Anita K ARIKA WIDYARINI Dina Maryati Doso, Tri Elfahmi . Endang Sri Rejeki Fransiska Leviana Galih Kurniawan Ika Purwidyaningrum Jamilah Sarimanah Jason Merari Peranginangin Lidia Kurniawati Imanuel Lola’ Tulak Rerung lrfan Zamzani Maryati, Dina Masyitah Novia Yanti Maulita Saraswati MELINDA WIDIANINGRUM Nabila K Nuraini Harmastuti Opstaria saptarini Patricia Alfayu Velix Puspitasari, Ismi Putri Rinda Pratiwi RA. Oetari Rahayu Rahmawati, Ismi Rica Rica Rica Rica, Rica Sari R Sari R, Sari Sarimanah, Jamilah Soemardji AA Syamsul Ma'arif Tan MI Titik Sunarni Titik Sunarni Tri Wijayanti Triana Hertiani Yolanda Yolanda Yolanda Yolanda, Yolanda Yul Mariyah Zahra Zahra Zahra Zahra Zakiyyah Qurrotul Aini Zamzani, Irfan