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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Penelitian Kesehatan Media Ilmu Kesehatan JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Farmasi Indonesia JFIOnline Abdimas Altruis: Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Kunir: Jurnal Farmasi Indonesia (KJFI)

Wiwin Herdwiani

Unknown Affiliation

Author-ID : 3553280

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 19 Documents Claim Missing Document

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UJI AKTIVITAS SITOTOKSIK EKSTRAK KULIT BATANG KAYU MANIS (Cinnamomum burmannii) TERHADAP KULTUR SEL T47D Wiwin Herdwiani; Endang Sri Rejeki
Jurnal Farmasi Indonesia Vol 12 No 2 (2015): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Cinnamon is plant commonly used as an aroma enhancer in cooking. Cinnamon can be used as an alternative cancer treatment. The content of cinnamon bark essential oil including, safrole, cinnamaldehyde, eugenol, tannins, flavonoids, saponins. This study aimed to examine the cytotoxic activity of ethanol extract skin cinnamon to inhibit T47D breast cancer cell activity. Ethanol extract skin cinnamon was obtained through maceration method by 96% ethanol. The content of flavonoids and cinnamaldehyde was detected by Thin Layer Chromatography (TLC). Cytotoxic test on breast cancer cells T47D used 3-[4,5-dimetilthiazol-2yl]-2,5-difeniltetrazolium bromide (MTT) method and the absorbance was read at ELISA reader. Parameter single cytotoxic test is IC50.and its cytotoxic activity was compared with doxorubicin. The result showed that ethanol extract skin cinnamon had cytotoxic effect on breast cancer T47D with IC50 71,157 Î¼g/ml. The ethanol extract skin cinnamon has the potential to be developed as a cemoprefentive agency.

Aktivitas Sitotoksik Ekstrak Etanol Kulit Buah Pinang (Areca catechu) dan Daun Kayu Manis (Cinnamomum burmanni) Wiwin Herdwiani; Soemardji AA; Elfahmi .; Tan MI; Nabila K; Anita K
Jurnal Farmasi Indonesia Vol 15 No 1 (2018): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

The areca plant (Areca cathecu) and cinnamon (Cinnamomum burmannii) haveanticancer properties. The aim of this research is to know the cytotoxic effect of Areca catechuof ethanol extract on T47D breast cancer cell culture and Cinnamomum burmannii leaves ofethanol extract on WiDr colon cancer cell culture.The obtained simplicia macerated to obtain ethanol extract of pinang peel and cinnamonleaves. The method used in testing cytotoxic activity was MTT (3- [4,5-dimethylthiazol-2yl] -2, 5-diphenyltetrazolium bromide) to obtain IC50 values.The results showed that ethanol extract of pinang peel and cinnamon leaf did not havecytotoxic effect on T47D culture with IC50 467,34 μg/mL and on WiDr culture with IC50 405,69μg/ml.

Perbandingan Efek Afrodisiaka Infusa dan Ekstrak n-Heksana Kuncup Bunga Cengkeh (Syzygium aromaticum L.) pada Tikus Putih Jantan Galur Wistar ARIKA WIDYARINI; YUL MARIYAH; WIWIN HERDWIANI
Jurnal Farmasi Indonesia Vol 9 No 1 (2012): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Clove (Syzygium aromaticum L.) flower bud is one of medicinal plant that is used as aphrodisiac. The study was aimed to find out the aphrodisiac effect of infuse and n-hexane extract of clove flower buds on climbing frequency of white male rats wistar strain and to know a higher aphrodisiac effect between infuse and n-hexane extract of clove flower buds. The test animals used were divided into four test groups. Group I (negative control) was given CMC 1%. Group II (positive control) was given Dji Wo capsul dose of 9 mg/200 g BW. Group III was given the n-hexane extract dose of 350 mg/200 g BW. Group IV was given the infuse dose of 350 mg/200 g BW. All preparations were given orally twice a day (morning and evening) for 5 days. At day-5, climbing frequency was observed and making vaginal smear to observe the male rat sperms. The climbing frequency data was analyzed using two ways Anova followed by Dunnett T3 test at 95% confidence. The result showed that infuse and n-hexane extract of clove flower buds had aphrodisiac effect on white male rat wistar strain and the infuse of clove flower buds had aphrodisiac effect similar with n-hexane extract.

Uji Efek Tonikum Infusa Batang Pasak Bumi dan Campuran Batang Pasak Bumi, Rimpang Jahe Merah dan Buah Cabe Jawa terhadap Mencit Putih Jantan MELINDA WIDIANINGRUM; - SUHARTINAH; WIWIN HERDWIANI
Jurnal Farmasi Indonesia Vol 9 No 1 (2012): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Eurycoma longifolia Jack. stem, Zingiber officinale Rosc. Var. Rubrum rhizome and Piper retrofractum fruits are traditional medicine plants, one of which is to overcome fatigue (tonic). This aim of the experiment was: first to find out whether infuse formula of single Eurycoma longifolia Jack. stem powder and infuse formula of a mixture of Eurycoma longifolia Jack., Zingiber officinale Rosc. rhizome, and Piper retrofractum fruit had tonic effect on male white mouse; the second, to obtain the most effective formula as tonic on for male white mouse. In this study the test animals were divided in 5 groups, and each group consisted of 5 male white mice, i.e. Group 1 F1 was Eurycoma longifolia Jack. stem, group II F2 was a mixture of (2:1:1), group III F3 was a mixture (1:1:1), group IV was positive control (caffeine), group V was negative control (distilled water). The study was conducted by making the orally given male white mice to swim, and then the exhausted times were observed and recorded before and after the treatment. The experiment concluded that first: infusa of single Eurycoma longifolia Jack. stem powder and infuse of a mixture of Eurycoma longifolia Jack., Zingiber officinale Rosc. rhizome, and Piper retrofractum fruit had tonic effect on male white mouse; the second, infuse of formula 3 (1:1:1) to have the best tonicum effect.

Hubungan Kepatuhan Penggunaan Obat terhadap Tekanan darah dan Kualitas Hidup Peserta Prolanis Hipertensi di Kabupaten Demak Galih Kurniawan; Ika Purwidyaningrum; Wiwin Herdwiani
Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i2.1704

Optimal quality of life for people with hypertension is very important so as not to reduce patient productivity. Adherence drug use is one of the factors thought to be associated with blood pressure and quality of life. This study aims to determine the relationship between adherence to medication use on blood pressure and quality of life of patients with hypertension in Prolanis . participants at the First Level Health Facility of the Klinik Pratama. This study used a cross sectional design involving hypertensive patients participating in Prolanis who met the inclusion and exclusion criteria at seven Primary Clinics in Demak Regency. Data on medication adherence were obtained using the MARS-5 questionnaire, quality of life data using the EQ-5D-5L questionnaire, and blood pressure data using a digital sphygmomanometer. The relationship between the level of compliance with blood pressure and the relationship between the level of compliance with quality of life was tested using Spearman rho analysis. The results of the study with a total of 87 respondents showed that most of them had moderate levels of adherence (52%), systolic blood pressure (64%) and diastolic blood pressure (57%) were not controlled and the average utility score was 0.845. There is a relationship between drug use adherence to systolic and diastolic blood pressure (P = 0.009), (P = 0.032) with a weak correlation level (r = 0.27), (r = 0.23) and there is a relationship between drug use adherence on quality of life (P = 0.000) with a moderate level of correlation (r = 0.42).

Co-Authors - SUHARTINAH Anita K ARIKA WIDYARINI Dina Maryati Doso, Tri Elfahmi . Endang Sri Rejeki Fransiska Leviana Galih Kurniawan Ika Purwidyaningrum Jamilah Sarimanah Jason Merari Peranginangin Lidia Kurniawati Imanuel Lola’ Tulak Rerung lrfan Zamzani Maryati, Dina Masyitah Novia Yanti Maulita Saraswati MELINDA WIDIANINGRUM Nabila K Nuraini Harmastuti Opstaria saptarini Patricia Alfayu Velix Puspitasari, Ismi Putri Rinda Pratiwi RA. Oetari Rahayu Rahmawati, Ismi Rica Rica Rica Rica, Rica Sari R Sari R, Sari Sarimanah, Jamilah Soemardji AA Syamsul Ma'arif Tan MI Titik Sunarni Titik Sunarni Tri Wijayanti Triana Hertiani Yolanda Yolanda Yolanda Yolanda, Yolanda Yul Mariyah Zahra Zahra Zahra Zahra Zakiyyah Qurrotul Aini Zamzani, Irfan

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