Article Per Year (5 Year)
p-Index From 2019 - 2024
1.405
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Pengabdian Pada Masyarakat Jurnal SOLMA JFIOnline JURNAL ILMU KEFARMASIAN INDONESIA J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Jurnal Insan Farmasi Indonesia Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Vivi Anggia, Vivi
UIN Syarif Hidayatullah Jakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health Other

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Pharmaciana: Jurnal Kefarmasian

 1 
Antioxidant and alpha-amylase inhibitory study of Sansevieria trifasciata Prain. leaves extract Vivi Anggia; Lusi Putri Dwita; Istikomah Istikomah
Pharmaciana Vol 9, No 1 (2019): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.847 KB) | DOI: 10.12928/pharmaciana.v9i1.11902

Abstract

Diabetes is one of the chronic diseases whose prevalence is increasing all over the world, including in Indonesia. Diabetes mellitus is characterized by high blood glucose levels that can be overcome by, for instance, inhibiting the alpha-amylase enzymes that play a role in carbohydrate hydrolysis. Several studies have proved that active antioxidant substances can also support the treatment of diabetic patients. Snake plant (Sansevieria trifasciata Prain.), or locally known as lidah mertua in Indonesia, is a traditional herbal used to treat diabetes. This study investigated the activity of the ethanol extract of S. trifasciata leaves in inhibiting α-amylase. The leaves were extracted by maceration with ethanol 70%, followed by phytochemical screening. The antioxidant activity was determined using the DPPH method, while the inhibition of α-amylase was measured using UV-Vis spectrophotometer at 524nm wavelength. The results showed that IC50 of the antioxidant activity was 1527.55 ppm, five times greater than the positive control, i.e., vitamin C. In the case of α-amylase enzyme, the IC50 of the ethanol extract of S. trifasciata leaves was 158.31 μg/ml and 0.26 times more potential than acarbose. The study has proved that the crude extract of S. trifasciata leaves has the potential as one of the antidiabetics and antioxidants that can be studied further. 
Co-Authors Amri Bakhtiar DAYAR ARBAIN Elfia Siska Yasa Putri Eureka Qurrotul Ainiyah Fauziah Ulfa Ramadhany Istikomah Istikomah Lusi Putri Dwita Nelly Suryani Nia Fachrunisa Nora Wulandari Rindita Rindita Supandi Supandi Tuti Wiyati Wiyati, Tuti Wulandari, Nora