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Analysis of secondary metabolite compounds from leaves extract kesambi (Schleichera oleosa) and antioxidant activity test Boima Situmeang; Weny Nuraeni; Agus Malik Ibrahim; Saronom Silaban
Jurnal Pendidikan Kimia (JPKim) Vol 8, No 3 (2016): Desember
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (411.191 KB) | DOI: 10.24114/jpkim.v8i3.4479

Abstract

Abstract. Kesambi (Schleichera oleosa) is one of plants that have the potential to treat various deasease. Kesambi plant or kusum widely spread in Asia such as India, Nepal, Malaysia and Indonesia. In Indonesia, this plant widely available in Java precisely Cilegon and Jember area. This study aimed to analyze the content of secondary metabolites from plants kesambi extract and antioxidant activity test of hexane, ethyl acetate and water fraction. Analysis of secondary metabolites is done with phytochemical and GC-MS test methods. Extraction was done by using maceration and fractionation methods. Antioxidan tactivity test using DPPH methods. The content of secondary metabolites contained in leaves kesambi (Schleichera oleosa) are flavonoids, alkaloids, tannins, phenols, and steroids. Based on IC50 values were obtained from three fraction, ethyl acetate fraction had a strong radical inhibition rate than the fraction of water and n-hexane. IC50 fraction of ethyl acetate, water, and n-hexane successively are: 206.0851; 272.2891 and 425,1143 ppm respectively. Keyword: kesambi, schleichera oleosa, DPPH, antioxidant
PENGEMBANGAN BAHAN AJAR INOVATIF RUMUS KIMIA DAN PERSAMAAN REAKSI BERBASIS MODEL PEMBELAJARAN PROBLEM BASE LEARNING (PBL) Ramlan Silaban; Saronom Silaban; Freddy T.M. Panggabean; Elsa Ginting
Jurnal Pendidikan Kimia (JPKim) Vol 7, No 1 (2015): April
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (512.229 KB) | DOI: 10.24114/jpkim.v7i1.5493

Abstract

Abstract The research aims to get an innovative chemistry teaching module on chemical formula and chemical equilibrium for X grade SMA  to improve student learning outcomes. This research conduct in some senior high school (SMA) in North Sumatera whose devide in two class, those  experiment and control class. This R&D type modifies from Borg&Gall theory, and some textbook contain this subject has been analyzing using BSNP criteria. The composed innovative teaching module trial on classroom by quasy-experiment methods. The experiment class taught using innovative teaching module and control class using textbook. The results showed that (1) Some chemistry textbook contain this subject which produced by some publisher has good quality but there are some sequences material and teaching strategy will be addition to completely them. (2) We have get a composing innovative teaching module on chemical formula and chemical equilibrium for X grade SMA on chemical formula and chemical equilibrium with combine PBL teaching model. This module have been standardization and fully criteria of BSNP. (3) There is a significant increasing of chemistry student learning outcomes using this innovative module on teaching classroom Keywords : development innovative teaching module; PBL model; learning outcomes
Kajian Ekspresi Gen Pretrombin-2 Manusia Sintetik pada Escherichia coli Secara In Silico Untuk Produksi Trombin Sebagai Komponen Lem Fibrin Saronom Silaban; Iman Permana Maksum; Sutarya Enus; Khomaini Hasan; Toto Subroto; Soetijoso Soemitro
Jurnal Pendidikan Kimia (JPKim) Vol 8, No 1 (2016): April
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (879.476 KB) | DOI: 10.24114/jpkim.v8i1.4425

Abstract

Abstrak. Pretrombin-2 merupakan prekursor trombin dan dapat berperan sebagai komponen lem fibrin (LF). LF merupakan biomaterial perekat yang dapat diaplikasikan sebagai pengganti teknik jahitan pasca operasi. Biomaterial ini terdiri dari trombin, fibrinogen dan faktor XIII sebagai komponen utamanya. Dalam LF, trombin rekombinan berperan sebagai enzim yang mengubah fibrinogen menjadi fibrin untuk membentuk benang-benang fibrin sehingga luka tertutup. Kajian ini bertujuan untuk memprediksi ekspresi gen pretrombin-2 (PT2) manusia sintetik pada Escherichia coli secara in silico. Urutan asam amino pretrombin-2 manusia yang diperoleh dari data GeneBank dirubah ke dalam bentuk wild type urutan nukleotida menggunakan software OPTIMIZER sesuai dengan kodon preferensi E. coli K12, Selanjutnya dianalisis dengan Graphical Codon Usage Analyzer dan dioptimasi secara menual berdasarkan preferensi kodon E. coli dari data Codon Usage Database. Untuk memprediksi tingkat ekspresinya pada inang E. coli, dipelajari kajian ekspresi PT2 secara in silico menggunakan perangkat lunak dalam jaringan OptimumGeneTM. Hasil analisis secara in silico urutan nukleotida PT2 hasil optimasi dan wild type terhadap kodon preferensi E. coli menunjukkan bahwa, persentase rata-rata kandungan GC hasil optimasi sebesar 54,71% sedangkan wild type 52,56%, PT2 hasil optimasi memiliki 100% kodon dengan frekuensi tinggi, sedangkan wild type hanya 67%, dan PT2 hasil optimasi memiliki nilai Codon Adaptasi Index  satu, sedangkan wild type hanya 0,89. Dengan demikian dapat diprediksi bahwa gen pretrombin-2 manusia sintetik kemungkinan akan diekspresikan tinggi di inang E. coli. Kata kunci: pretrombin-2, trombin, kodon preferensi, kajian ekspresi, E. coli
PENGARUH PENGGUNAAN MEDIA ANIMASI KOMPUTER DAN MOTIVASI BELAJAR DALAM PEMBELAJARAN REAKSI REDOKS DAN ELEKTROKIMIA TERHADAP PRESTASI BELAJAR MAHASISWA Freddy Tua Musa Panggabean; Saronom Silaban
Jurnal Pendidikan Kimia (JPKim) Vol 7, No 1 (2015): April
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (405.265 KB) | DOI: 10.24114/jpkim.v7i1.5496

Abstract

Abstract This research aim to know how effect of computer animation instructional media and student motivation for student learning outcomes on teaching redox reaction. The quasy experiment methods conduct and achievement test using as instrument. Data was analysed using inferential statistic method. The results and hypothesis test shows: (1) there is a significant influence the use of computer animation media on learning redox reaction and electrochemical to achievement of students, in which chemistry learning achievement of students taught using computer animation media (84.38) is higher compared chemistry learning achievement of students who are taught without using the computer animation media (78.25), (2) there is a significant influence on learning motivation to achievement of students, in which chemistry learning achievement of students who have a high learning motivation (84.59) higher than chemistry learning achievement of students who have a low learning motivation (78.89), and (3) there is no significant influence of the interaction between the use of computer animation media and learning motivation of students to achievement of student.Kata kunci: Media Animasi, Motivasi, Prestasi Belajar, Kimia.
PENGARUH MODEL PEMBELAJARAN Contextual Teaching And Learning (CTL) TERHADAP HASIL BELAJAR SISWA PADA POKOK BAHASAN SISTEM KOLOID Saronom Silaban; Neeta Sri Debora Simangunsong
Jurnal Pendidikan Kimia (JPKim) Vol 7, No 1 (2015): April
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.429 KB) | DOI: 10.24114/jpkim.v7i1.5507

Abstract

AbstrakPenelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Contextual Teaching and Learning (CTL) terhadap hasil belajar siswa dalam pembelajaran kimia pada pokok bahasan sistem koloid. Penelitian ini telah dilakukan di SMA Methodist 1 Medan. Kelas sampel (kelas XI) diberikan perlakuan dengan model pembelajaran CTL. Kelas sampel telah memenuhi kriteria uji normalitas dan homogenitas. Evaluasi awal(pre-tes) siswa kelas sampel rata-rata M=16.25±6.25. Setelah perlakukan pembelajaran menggunakan model CTL, rata-rata pencapaian siswa (post-tes) meningkat menjadi M=76.39±6.09. Meningkatnya rata-rata post-tes siswa tersebut mengindikasikan bahwa pembelajaran menggunakan model CTL dapat meningkatkan hasil belajar siswa. Keberhasilan belajar ditandai dengan peningkatan hasil belajar siswa, dimana dalam perhitungan keberhasilan belajar berdasarkan %gain diperoleh rata-rata keberhasilan siswa sebesar 72% Hasil analisis uji beda atau uji t diperoleh thitung > ttabel (6,34> 1,6905) pada α = 0,05 yang berarti pembelajaran menggunakan CTL berpengaruh positif terhadap siswa dalam meningkatkan hasil belajarnya pada pokok bahasan sistem koloid.Kata Kunci: Pembelajaran CTL, sistem koloid, hasil belajar siswa
The Development of Chemical Practice Guidebook Colloid System-Based Integrated Contextual Character Values Ester Manalu; Saronom Silaban; Ramlan Silaban; Wesly Hutabarat
Jurnal Pendidikan Kimia (JPKim) Vol 8, No 2 (2016): Agustus
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (379.834 KB) | DOI: 10.24114/jpkim.v8i2.4429

Abstract

Abstract- This research is a development that aims to develop guiding chemistry lab contextually based integrated character values, knowing improving student learning outcomes in terms of cognitive and determine student learning outcomes in terms of affective and psychomotor using guiding chemistry laboratory that has been developed , The study was conducted in Cahaya Medan high school. Samples are two classes were taken by purposive sumpling using PPKBK experimental class I and class II experiment using PP available in school study instrument is a rubric validation, test and observation sheet. Research began on analytical chemistry lab at the school guidance, development, validation, revision and test laboratory guides that have been developed. The product of research is (1) based on the analysis of chemical PP book in colloidal system materials publisher grants, Pudak Scientific, Duta Nusantara and Laskar Aksara is not in accordance with BSNP, (2) based PPKBK BSNP integrated character values is more valid than the PP chemicals used in schools, 93) there is a difference in improving student learning outcomes in terms of cognitive, that learned to use the integrated PPKBK character values of 0.73, while that learned with chemicals used PP 0,63 school, (4) there are differences in student learning outcomes in terms of psychomotor aspect that learned to use PPKBK integrated character values at 91 and that learned with PP chemicals used school at 85, while in terms of affective aspects that learned to use PPKBK integrated character values of 92 and PP with chemicals schools at 81. Keywords: Development of practical guidance, based contextual character values, the colloid system
Co-Authors Boima Ramses Situmeang Elsa Ginting Ester Manalu Freddy T.M. Panggabean Freddy Tua Musa Panggabean Ibrahim, Agus Malik Iman Permana Maksum Khomaini Hasan Neeta Sri Debora Simangunsong Ramlan Silaban Soetijoso Soemitro Sutarya Enus Toto Subroto Weny Nuraeni Wesly Hutabarat