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All Journal JPP Jurnal Kesehatan Poltekkes Palembang Jurnal Pengabdian kepada Masyarakat (ABDIKEMAS)
Ratnaningsih Dewi Astuti
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Dentistry Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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PENGARUH SUHU PENYIMPANAN KOMBINASI AMOKSISILIN DAN ASAM KLAVULANAT DALAM SEDIAAN DRY SIRUP TERHADAP DAYA HAMBAT BAKTERI (Staphylococcus aureus) Muhamad Taswin .; Ratnaningsih Dewi Astuti; Bherta Tiara Handayani
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 16 No 1 (2021): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : POLITEKNIK KESEHATAN KEMENKES PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v16i1.690

Abstract

Sediaan dry sirup kombinasi amoksisilin dan asam klavulanat merupakan obat pilihan pertama untuk pengobatan penyakit infeksi seperti pneumonia. Sediaan dry sirup kombinasi amoksisilin dan asam klavulanat merupakan sediaan antibiotik yang perlu disuspensikan terlebih dahulu sebelum digunakan. Suhu penyimpanan dan stabiltas zat aktif didalam sediaan sangatlah penting karena dengan adanya penambahan air didalam sediaan suspensi kombinasi amoksisilin dan asam klavulanat akan mempengaruhi degradasi kimiawi, fisik dan mikrobiologi. Penelitian ini bertujuan untuk mengukur adanya pengaruh suhu penyimpanan kombinasi amoksisilin dan asam klavulanat dalam sediaan dry sirup yang telah disuspensikan terhadap daya hambat bakteri Staphylococcus aureus. Jenis penelitian ini adalah penelitian eksperimental karena adanya perlakuan terhadap sediaan antibiotik kombinasi amoksisilin dan asam klavulanat yang dipengaruhi oleh suhu penyimpanan terhadap aktivitas antibakteri. Berdasarkan hasil pengukuran diameter daya hambat pada antibiotik suspensi kombinasi amoksisilin dan asam klavulanat pada penyimpanan hari ke-7 semua sampel suspensi dry sirup mengalami penurunan. Penurunan diameter zona hambat tertinggi terjadi pada sampel suspensi dry sirup generik yang disimpan pada suhu kamar. Dari hasil penelitian dapat disimpulkan bahwa adanya pengaruh suhu penyimpanan kombinasi amoksisilin dan asam klavulanat dalam sediaan dry sirup terhadap daya hambat bakteri Staphylococcus aureus dengan adanya penurunan daya hambat di akhir penyimpanan
PENGARUH PEMBERIAN EKSTRAK ISOFLAVON TEMPE TERHADAP TINGKAT STRESS OKSIDATIF PADA TIKUS PUTIH JANTAN GALUR WISTAR (Rattus novergicus) SETELAH DIINDUKSI DENGAN DOSIS TOKSIK PARASETAMOL Muhamad Taswin; Ratnaningsih Dewi Astuti; Dewi Marlina; Ocktariyana Ocktariyana; Ade Agustianingsih
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 17 No 2 (2022): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : POLITEKNIK KESEHATAN KEMENKES PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v17i2.1513

Abstract

ABSTRACT Background: As a producing country and at the same time the largest consumer of tempeh in the world, Indonesia has become the largest soybean market in Asia. As much as 50% of soybean consumption in Indonesia is done in the form of tempeh. Tempe is a potential food ingredient as a hepatoprotector. The content of isoflavones in tempeh has been shown to protect rat liver function under stress conditions. Isoflavones contained in tempeh have activity as antioxidants, which can prevent oxidation reactions from occurring by working as reducing agents and protecting cell membranes from oxidation, as well as counteracting free radicals by stopping chain reactions and protecting cells from DNA activation so as to reduce cell damage. This situation has prompted the authors to investigate the effect of the isoflavone extract of tempeh on the histochemistry and histopathology of the livers of male white Wistar rats (Rattus novergicus) after being induced by toxic doses of Paracetamol. Methods: This study was an experimental study using the Randomized Posttest Only Control Group Design to determine the level of oxidative stress after administration of tempeh isoflavone extract to male white rats (Rattus novergicus) induced with a toxic dose of paracetamol. 5 groups, namely group 1 was given tempe extract 160 mg/kgBB, group 2 was given tempe extract 320 mg/kgBB, group 3 was given tempe extract 640 mg/kgBB, group 5 was given distilled water and group 6 was given 1% NaCMC solution. Each rat was treated for 14 days. On day 12, 13 and 14 rats were given paracetamol at a dose of 900 mg/kg BW in 1% NaCMC. And on the 15th day, rat blood serum was examined for levels of SGOT, SGPT and MDA. Results: It was found that tempeh at a dose of 640 mg/kgBW could significantly reduce SGOT, SGPT and MDA levels (p<0.05) compared to other doses as well as distilled water and 1% NaCMC. Conclusion: So it can be concluded that tempeh can be an alternative source of antioxidants that can protect liver cells from the effects of substances that can damage the liver. Keywords: Tempe, SGOT, SGPT, MDA
PENINGKATAN PENGETAHUAN DAN KETERAMPILAN DASAR DALAM PELAYANAN KEFARMASIAN DI APOTEK BAGI LULUSAN SMK FARMASI NOL TAHUN DI KOTA PALEMBANG Ratnaningsih Dewi Astuti; Muhamad Taswin
ABDIKEMAS: Jurnal Pengabdian Kepada Masyarakat Vol 2 No Tahun (2020): Jurnal Pengabdian kepada Masyarakat (ABDIKEMAS)
Publisher : PUSAT PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT, POLITEKNIK KESEHATAN KEMENTERIAN KESEHATAN PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (279.277 KB) | DOI: 10.36086/j.abdikemas.v2iTahun.1196

Abstract

One level of education that contributes to the workforce is vocational high school (SMK). Pharmacy Vocational School graduates do not have adequate skills and abilities in administrative management in pharmacies so that results are still not good. The impact is that graduates of Pharmacy Vocational Schools are generally not ready to work in the world of work, they need an internship first to get used to working in a pharmacy. The Department of Pharmacy, Poltekkes Palembang, as a partner institution that APMFI has always asked for as examiners at the UPK of Pharmacy Vocational Schools in South Sumatra, has improved the basic knowledge and skills of zero-year Pharmacy Vocational School graduates in the city of Palembang in pharmaceutical services at pharmacies so that they become more ready to use, through training activities in the form of theoretical presentation accompanied by individual practice and group service simulations. The pretest results of the training participants with an average point of 7.91 showed that only about 50% of the material they knew and from the posttest results obtained an average of 10.67, which is about 70% of the material. The lowest score from 4 increased to 7 and the highest score increased from 12 (1 person) to 14 (3 person). From the statistical test of paired t-test (p<0.05) it was found that the results of the pretest-posttest showed a significant change. The conclusion of community service from the Department of Pharmacy with the theme of Increasing Basic Knowledge and Skills in Pharmaceutical Services at Pharmacies for Graduates of the Zero Year Pharmacy Vocational School in Palembang City shows positive and beneficial results for its targets. In addition, this activity has also been able to introduce the Department of Pharmacy to Pharmacy Vocational School graduates so that it is expected to increase the interest of Sipenmaru Poltekkes Palembang participants in 2016 in general and in particular the Department of Pharmacy.
PENDAMPINGAN DAN PELATIHAN SENAM KOMBINASI ABDOMINAL STRETCHING EXERCISE PADA REMAJA PUTRI YANG MENGALAMI DISMENORE Heni Sumastri; Ocktariyana Ocktariyana; Indah Puji Septeria; Ratnaningsih Dewi Astuti
ABDIKEMAS: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 2 Desember (2022): Jurnal Pengabdian kepada Masyarakat (ABDIKEMAS)
Publisher : PUSAT PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT, POLITEKNIK KESEHATAN KEMENTERIAN KESEHATAN PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (406.111 KB) | DOI: 10.36086/j.abdikemas.v4i2 Desember.1472

Abstract

Abdominal stretching exercise merupakan latihan peregangan otot perut dan dapat digunakan untuk mengurangi rasa nyeri pada menstruasi. Berdasarkan studi pendahuluan di SMA Kota Palembang didapatkan bahwa masih banyak siswi yang mengalami nyeri haid (dismenore) dan pada saat mengalami nyeri haid beberapa siswi meminta izin pulang ke rumah dan akhirnya tidak dapat mengikuti proses pembelajaran di sekolah. Tujuan dari kegiatan Pengabdian kepada masyarakat ini untuk membantu Remaja Putri mengatasi nyeri haid dengan melakukan senam kombinasi dismenore dan abdominal stretching exercise. Metode dalam kegiatan ini dengan Pelatihan dan Pendidikan kesehatan. Hasil yang didapat pada kegiatan pengabdian kepada masyarakat ini adalah duta abdominal stretching exercise mampu mempraktikkan kembali senam kombinasi abdominal stretching exercise dengan benar. Selain itu, siswi yang mengalami dismenore mampu mengatasi keluhan nyeri selama menstruasi yang cara melakukan senam kombinasi abdominal stretching exercise. Kami menyarankan bahwa kegiatan ini sebaiknya dilakukan secara terus menerus dan berkesimbungan oleh pihak Mitra sehingga tingkat pada remaja putri dapat mengatasi dismenorea dengan cara senam kombinasi Abdominal Stretching Exercise. Senam ini dapat dilakukan pada siswa SMA dengan keluhan nyeri haid secara teratur sesuai dengan standar operasional protokol (SOP) dan video senam dismenorre. Kata kunci: Abdominal stretching exercise. Dismenore, Pelatihan, Senam, Siswa.
PENDAMPINGAN KESIAPTERAPAN DESA SIAGA DAN PEMANFAATAN RUMAH PINTAR SEDERAHANA DI DESA LALANG SEMBAWA KECAMATAN SEMBAWA KABUPATEN BANYUASIN Marta Pastari; Heni Sumastri; Ratnaningsih Dewi Astuti
ABDIKEMAS: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 2 Desember (2022): Jurnal Pengabdian kepada Masyarakat (ABDIKEMAS)
Publisher : PUSAT PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT, POLITEKNIK KESEHATAN KEMENTERIAN KESEHATAN PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (590.241 KB) | DOI: 10.36086/j.abdikemas.v4i2 Desember.1514

Abstract

Abstract The condition of Lalang Sembawa Village, which is a division area, still needs guidance from several sectors, especially in the health, education and community economic sectors. Moreover, the condition of the village area has quite a large percentage of poor families and there is a risk of dropping out of school for children from these families. Lalang Sembawa Village is also a fostered partner village of the Palembang Ministry of Health Poltekkes which is planned to become an Alert Village especially in the education and health sectors. Based on the potential and existing problems, several efforts were made to solve the problem: a) Formation and strengthening of standby villages; b) Increasing access to education; through the establishment of a “Simple Smart Home”. Activities related to the strengthening of the standby village are realized through the commitment of the standby village and management can be made. Apart from that, the planned simple smart house has also been realized with the supervisor coming from the local PAUD leaders and teachers. Activities focused on getting students used to group study and increasing creativity have also been realized. Keywords: Standby Villages, Simple Smart Home, dropping out of school for children
Co-Authors Ade Agustianingsih Bherta Tiara Handayani Dewi Marlina Heni Sumastri Indah Puji Septeria Marta Pastari Muhamad Taswin Muhamad Taswin . Ocktariyana, Ocktariyana