Lita Rakhma Yustinasari
Department Of Veterinary Anatomy, Faculty Of Veterinary Medicine, Universitas Airlangga

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Mozart KV 448 Menurunkan Densitas dan Aktivitas Neuroglia Hipokampus Mencit (Mus musculus) Selama Stres Prenatal No. 416-KE Shelly Kusumarini; Lita Rakhma Yustinasari; Eka Pramystha Hestianah; Suryo Kuncorojati; Tutik Juniastuti
Jurnal Sain Veteriner Vol 35, No 1 (2017): Juni
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1258.378 KB) | DOI: 10.22146/jsv.29279

Abstract

The aim of this research was to explore the influence of Mozart KV 448 classical music therapy to the neuroglia cells of mice’s hippocampus that were exposed to stress during prenatal. This research were employing twenty female mices and twenty male mices. Female mices were estrus synchronized with PMSG and hCG then monomating to the males. Pregnant females were then divided into four groups (P0, P1, P2, P3). P0 was as control, P1 was treated by one minute forced swim test, P2 was treated by one minute forced swim test followed by thirtyminutes classical music Mozart KV 448 and P3 was treated by one minute forced swim test followed by sixty minutes classical music Mozart KV 448. This research was carried out for twenty-one days during gestation period. The neuroglia density result was analyzed using ANOVA and Duncan test. The neuroglia activity result wasanalyzed using Kruskal wallis test and Z test. The histology reading showed degradation of density and activity of hippocampus neuroglia.
Uji Aktivitas Antibakteri dari Ekstrak n-Heksana dan Kloroform Daun Sirsak (Annona muricate L.) Terhadap Pertumbuhan Bakteri Staphylococcus aureus Secara In Vitro Werenfridus Kono Lake; Iwan Sahrial Hamid; Amung Logam Saputro; Hani Plumeriastuti; Lita Rakhma Yustinasari; Maya Nurwartanti Yunita
Jurnal Medik Veteriner Vol. 2 No. 1 (2019): April
Publisher : Faculty of Veterinary Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.135 KB) | DOI: 10.20473/jmv.vol2.iss1.2019.60-65

Abstract

Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri daun sirsak terhadap Staphylococcus aureus. Ekstraksi diproses dengan metode maserasi terlebih dahulu dengan n-heksana kemudian kloroform. Aktivitas antibakteri diukur secara in vitro dengan menggunakan metode difusi agar menggunakan paperdisk. Aktivitas antibakteri diuji dengan analisis variansi (ANOVA) dengan nilai signifikansi 0,5% untuk mengetahui pengobatan mana yang memiliki efek atau berbeda secara signifikan dengan dosis masing-masing 300 mg/ml, 250 mg/ml, 200 mg/ml, 150 mg/ml, 100 mg/ml dan menghasilkan aktivitas antibakteri dengan zona hambat berturut-turut 16,70 mm; 14,05 mm; 11,45 mm; 9,85 mm; 3,00. Hasil pemeriksaan aktivitas antibakteri menunjukkan ekstrak n-heksana dan kloroform dapat menghambat pertumbuhan Staphylococcus aureus pada konsentrasi 250 mg / ml dengan diameter zona hambat 14,05 mm. Ekstrak dengan aktivitas tertinggi ditentukan konsentrasi hambat tumbuh minimum (MIC). Ekstrak kloroform daun sirsak dari bakteri Staphylococcus aureus yang berada pada konsentrasi 100 mg/ml dengan zona hambat 3,00 mm.
EFFECT OF Polygonum minus (KESUM) LEAVES ETHANOLIC EXTRACT ON HISTOPATHOLOGICAL CHANGES ON THE WALL AORTA OF MICE (Mus musculus) INDUCED BY CADMIUM CHLORIDE ANTIOXIDANT Putri Anggraheni Kusumaningrum; Lita Rakhma Yustinasari; Iwan Sahrial Hamid; Sri Agus Sudjarwo; Kuncoro Puguh Santoso; Chairul Anwar
Journal of Basic Medical Veterinary Vol. 8 No. 2 (2019): Journal of Basic Medical Veterinary, December 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v8i2.20408

Abstract

This study was conducted to investigate the protective effect Polygonum minus leaves extract on the histopathological changes on aorta wall of mice (Mus musculus) induced by cadmium chloride. Thirty male mice were divided into five groups and were administered via intragastric gavage with different treatments for 21 days. The treatment were Negative Control (CMC Na 0.5% solution + aquadest), Positive Control (CMC Na0.5% solution + 8 mg/kg bw of mercuric chloride), Treatment 1, 2, and 3 (200, 400, and 800 mg/kg bw of Polygonum minus leaves extract respectively + 8 mg/kg bw of cadmium chloride). The microscopec examine followed analyzed by One Way ANOVA continued with Duncan test for counting the amount of foam cell and the histopathological changes of wall aorta were examined by using Ifora Scoring method was analysed using Kruskal Wallis and continued with Mann-Whitney test. The result showed Polygonum minus leaves extract could protect wall aorta of mice from the damage effect of cadmium chloride. The best dose of Polygonum minus on this research was 400 mg/kg bw.
THE EFFECT OF POLYPROPYLENE PLASTIC RESIDUE ON HEATED PALM OIL AGAINST HISTOPATHOLOGICAL CHANGES OF SMALL INTESTINE ON MALE WHITE RAT (Rattus norvegicus) WISTAR STRAIN Aulia Puspa Amaris; Lita Rakhma Yustinasari; Djoko Legowo; Hani Plumeriastuti; Chairul Anwar; Nove Hidajati
Journal of Basic Medical Veterinary Vol. 8 No. 2 (2019): Journal of Basic Medical Veterinary, December 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v8i2.20409

Abstract

This study was conducted to investigate the effect of polypropylene residue on heated palm oil against histopathological changes of small intestine on male white rat (Rattus norvegicus) wistar strain. Eighteen male white rats divided into three groups and were administered via peroral gavage with different treatments for five weeks. The treatment were Control (84 grams palm oil), P1 (84 grams palm oil with 2.3 grams plastic), and P2 (84 grams palm oil with 6.81 grams plastic). The histopathological changes of small intestine were examined by using Barthel Scoring method was analysed using Kruskal Wallis and continued with Mann-Whitney test. The result showed that were significant difference (p<0.05) between treatment groups. The worse damage of polypropylene plastic residue was 6.81 grams.