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All Journal Pharmascience Panrita Abdi - Jurnal Pengabdian pada Masyarakat Jurnal Ilmu Kesehatan Journals of Ners Community Journal of Health Sciences Journal of Community Empowerment for Health Abdimasku : Jurnal Pengabdian Masyarakat Caring : Indonesian Journal of Nursing Science Indonesian Journal of Cancer Lux Mensana: Journal of Scientific Health Indonesian Nursing Journal of Education and Clinic (Jurnal Pendidikan dan Praktik Keperawatan Indonesia) Equalegum International Law Journal Synthesis Global Health Journal Diversity Logic Journal Multidisciplinary
Yuanita Syaiful
Adi Husada Institute Of Health Science
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Pharmascience

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Antihiperglikemik Infus Bunga Labu Kuning (Cucurbita moschata Duch) Terhadap Kadar Glukosa Darah Mencit Terpapar Streptozotocin Mono Pratiko Gustomi; Yuanita Syaiful; Suwanto Suwanto
Jurnal Pharmascience Vol 6, No 1 (2019): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i1.6083

Abstract

ABSTRAK Indonesia merupakan negara kaya dengan kekayaan alam yang dapat dimanfatkan sebagai kesehatan, pangan, papan dan energi. Tanaman labu kuning merupakan bagian dari sumber kekayaan alam. Bunga labu kuning memiliki senyawa aktif seperti flavonoid, beta-karoten, vitamin C, dan vitamin E. Senyawa tersebut dapat dimanfaatkan sebagai pengobatan diabetes mellitus. Penelitian ini bertujuan untuk mengetahui  antihiperglikemik infus bunga labu kuning terhadap kadar glukosa darah mencit terpapar streptozotocin. 24 ekor mencit digunakan dalam penelitian dibagi 2 kelompok antara lain mencit non diabet dan mencit diabet hasil induksi streptozotocin. Analisa data menggunakan Uji t. Sedangkan untuk mengetahui perbedaan perubahan glukosa darah acak dengan kelompok perlakuan dilakukan uji Anova dan dilanjutkan dengan uji Post Hoc Duncan. Hasil penelitian bahwa induksi streptozotocin dan pemberian lard berpengaruh terhadap perubahan glukosa darah acak. Adapun nilai perubahan glukosa darah acak sebelum dan sesudah induksi streptozotocin dan lard sebanyak 120 mg/dl dan 226 mg/dl. Pemberian infus bunga labu kuning berpengaruh terhadap penurunan glukosa dara acak mencit diabet akibat induksi streptozotocin. konsentrasi 10% infus bunga labu kuning lebih efektif dibandingkan dengan konsentrasi 5% dan 20%. Berdasarkan penelitian ini bahwa induksi streptozotocin dan pemberian lard berpengaruh terhadap perubahan glukosa darah acak. Sedangkan pemberian infus bunga labu kuning berpengaruh terhadap penurunan glukosa dara acak mencit diabet akibat induksi streptozotocin dan pemberian lard.Kata kunci: Antihiperglikemik, labu kuning, streptozotocin  ABSTRACT  Indonesia is a country rich with natural resource that can be utilized as health, food, shelter and energy. Pumpkin plants are part of natural resource. Pumpkin flower have active compounds such as flavonoids, beta-carotene, vitamin C, and vitamin E. These compounds can be used as a treatment of diabetes mellitus. This study aims to determine antihyperglycemic pumpkin infusion on blood glucose levels in mice induction of streptozotocin. 24 mice were used in the study divided into 2 groups, among others, non diabetic mice and diabetic mice induced streptozotocin induction. Data were analyzed using T-test. Meanwhile, to know the difference of random blood glucose change with treatment group was done by Anova test and continued by Post Hoc Duncan test. The results of the research that the induction of streptozotocin and lard Award effect on random blood glucose change. The value of the random blood glucose changes before and after induction of streptozotocin and lard as much as 120 mg / dl and 226 mg / dl. Giving pumpkin flower infuse effect on random blood glucose lowering diabetic mice induced by streptozotocin. The concentration of 10% infusion of pumpkin flower is more effective than the concentration of 5% and 20%. Based on this research that the induction of streptozotocin and lard Award effect on random blood glucose change. While the provision of pumpkin flowers infuse effect on random blood glucose lowering induced by streptozotocin-diabetic mice and administration of lard.  Keywords: Antihiperglikemik, pumpkin, streptozotocin
Co-Authors Agus Wahyudi Aidatur Runis Arum Ayu Ning Tias Chumairotur Robi'ah Dewi Masruroh Diyah Ratnawati Dwi Wahyuni Rahmawati Dwi Wulaningsih Emi Indrawati Eni Mujafafa Esni Lailatul Khariroh Imam Burhanuddin Baharsyah Istiroha Istiroha Kusrotin Nikmah Lilis Fatmawati Lilis Fatmawati Lilis Fatmawati Lilis Fatmawati Lilis Fatmawati Lilis Fatmawati Lilis Fatmawati Lina Madyastuti Rahayuningrum LINA MADYASTUTI RAHAYUNINGRUM Mafrukahtul Firdani Maslachah Maslachah Merinne Tamada Mono Pratiko Gustomi Mukhlishotin Mukhlishotin Nur Afni Wulansari NUR HIDAYATI Nurhani Nurhani Nurwan Nurwan Qonitatin Wafiyah Ratnawati, Diyah Retno Twistiandayani Riski Aristantia Rita Rahmawati Riwahtini Riwahtini Robiatul Adawiyah Roihatul Zahroh Setya Wibawa Sheintia Prihastuti Sigit Hendro Rachmawan Siti Aminah Siti Choiriyah Siti Nur Qomariah Siti Sholichah Siti Varyal Naftalin Sri Hartutik Sumiyati Sumiyati Suwanto Suwanto Umi Barrotul Wanda Mahfuzatin Nafisah Yenny Hariyanto Zahroh, Roihatul Zahrotul Nisak