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All Journal Jurnal Biologi Tropis JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Fatikha Rudia Ahda
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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HIPERTENSI, DIABETES MELLITUS, DAN OBESITAS SEBAGAI FAKTOR KOMORBIDITAS UTAMA TERHADAP MORTALITAS PASIEN COVID-19: SEBUAH STUDI LITERATUR Luh Ade Dita Rahayu; Jannatul Cahya Admiyanti; Yumna Iftinan Khalda; Fatikha Rudia Ahda; Nur Feby Febiana Agistany; Sastraningsih Setiawati; Nabila Indah Shofiyanti; Cut Warnaini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 9 No 1 (2021): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 9.1 Edisi Maret - Juli
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v9i1.342

Abstract

Background: COVID-19 patients with comorbid diseases have a higher mortality rate than patients without congenital diseases. The most common comorbids found in COVID-19 patients are diabetes mellitus, hypertension, and obesity. The prevalence of COVID-19 patients with diabetes mellitus reached 41.7%, hypertension reached 56.6%, and obesity reached 41.7%. Methods: The method used in this paper is literature review from various references and focused on the correlation of comorbid with the risk of death in COVID-19 patients. The references are being retrieved from NCBI and Google Scholar. Overall, 21 sources were used which were obtained from various data bases including PubMed, ScienceDirect, Researchgate, and WHO. Discussion: There is an increase in ACE-2 expression which causes a high susceptibility to SARS-CoV-2 infection on COVID-19 patient with hypertension. Impaired T-cell function and increased levels of interleukin-6 (IL-6) also play an important role in increasing the severity on COVID-19 patient with diabetes. Obesity can cause abnormalities in the secretion of cytokines, adipokines, and inferferon which will disrupt the immune system in the human body. Conclusion: The complex pathophysiological mechanisms of hypertension, diabetes mellitus, and obesity as comorbid in COVID-19 patients increase the severity and mortality risk.
Most Common Sexually Transmitted Infections in LGBT Baiq Henny Salim Alawiyah; Alfia Mawaddah; Annisa Diyanabila Indrasari; Ayundha Rizky Lestari; Diki Wahyudi; Fatikha Rudia Ahda; I Gede Aditya Satrya Bhuwana Cakra; Ni Made Ayu Shinta Dewi; Rida Dwi Arista; Puji Widyastuti; Talitha Syahla; Vanessa Essianda; Yunita Hapsari
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.5804

Abstract

Sexually Transmitted Infections (STIs) are infections that are transmitted through sexual contact with an infected partner through vaginal, oral and anal sex. STIs can also be transmitted from mother to child during pregnancy, childbirth, and breastfeeding. LGBT is a group at high risk of contracting STIs, especially syphilis. Syphilis rates increased every year by 28.6% from 2020 to 2021. LGBT people accounted for 47% (18,381) of syphilis cases and (44%) LGBT people who had syphilis also had HIV. This article was written with the aim of finding out more about the molecular biology, phatophysiology and clinical symptoms of syphilis. The method used is a literature review on the NCBI website, Google Scholar, and Research Gate. It can be concluded that syphilis can be cured in the early stages of infection, but if adequate treatment is not received it can become a systemic infection and progress to the latent phase. Syphilis can also increase the risk of transmitting HIV which cannot be cured but can take medication to treat the symptoms. In conclusion, LGBT is a group at high risk of contracting STIs. The reason is, they have different sexual lives in general. The sexual activities carried out are anal sex, oral sex and variations thereof. Anal sex has a potential risk of injury to the anus. Because the anus is not elastic, sexual intercourse carries a risk of injury, so syphilis is more easily transmitted if there is damage to the anal area.
Co-Authors Alfia Mawaddah Annisa Diyanabila Indrasari Ayundha Rizky Lestari Baiq Henny Salim Alawiyah Cut Warnaini Diki Wahyudi I Gede Aditya Satrya Bhuwana Cakra Jannatul Cahya Admiyanti Luh Ade Dita Rahayu Nabila Indah Shofiyanti Ni Made Ayu Shinta Dewi Nur Feby Febiana Agistany Puji Widyastuti Rida Dwi Arista Sastraningsih Setiawati Talitha Syahla Vanessa Essianda Yumna Iftinan Khalda Yunita Hapsari